RU2648144C2 - КОМПОЗИЦИИ, СОДЕРЖАЩИЕ ГЕТЕРОГЕННЫЕ ПОПУЛЯЦИИ РЕКОМБИНАНТНЫХ БЕЛКОВ ЧЕЛОВЕЧЕСКОГО ФАКТОРА СВЕРТЫВАНИЯ КРОВИ Ха - Google Patents
КОМПОЗИЦИИ, СОДЕРЖАЩИЕ ГЕТЕРОГЕННЫЕ ПОПУЛЯЦИИ РЕКОМБИНАНТНЫХ БЕЛКОВ ЧЕЛОВЕЧЕСКОГО ФАКТОРА СВЕРТЫВАНИЯ КРОВИ Ха Download PDFInfo
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| PCT/IB2014/064564 WO2015044836A1 (en) | 2013-09-24 | 2014-09-16 | Compositions comprising heterogeneous populations of recombinant human clotting factor xa proteins |
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| KR20150103205A (ko) | 2013-01-31 | 2015-09-09 | 화이자 인코포레이티드 | 인자 Xa 억제를 길항하기 위한 조성물 및 방법 |
| SG11201601221XA (en) | 2013-09-24 | 2016-04-28 | Pfizer | Compositions comprising heterogeneous populations of recombinant human clotting factor xa proteins |
| EP4588932A3 (en) * | 2016-06-17 | 2025-10-01 | Alexion Pharmaceuticals, Inc. | Preparation of factor xa derivatives |
| EP3722418A1 (en) * | 2019-04-08 | 2020-10-14 | AB Enzymes Oy | Solution stable enzyme composition |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US20090175931A1 (en) * | 2005-11-15 | 2009-07-09 | Camire Rodney M | Compositions and methods for modulating hemostasis |
| RU2396347C2 (ru) * | 2004-08-17 | 2010-08-10 | Ксл Бехринг Гмбх | Модифицированные витамин к-зависимые полипептиды |
| WO2013049804A1 (en) * | 2011-09-30 | 2013-04-04 | The Children's Hospital Of Philadelphia | Compositions and methods for modulating hemostasis |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US5597799A (en) | 1990-09-04 | 1997-01-28 | Cor Therapeutics, Inc. | Recombinant agents affecting thrombosis |
| AT405517B (de) | 1997-02-27 | 1999-09-27 | Immuno Ag | Faktor x-deletionsmutanten und analoge davon |
| AT405516B (de) | 1997-02-27 | 1999-09-27 | Immuno Ag | Faktor x-analoge mit modifizierter proteasespaltstelle |
| AT410216B (de) | 1999-08-10 | 2003-03-25 | Baxter Ag | Faktor x-analogon mit verbesserter aktivierbarkeit |
| US20040102388A1 (en) | 2000-03-22 | 2004-05-27 | High Katherine A. | Modified blood clotting factors and methods of use |
| FR2831170B1 (fr) | 2001-10-19 | 2004-03-19 | Inst Nat Sante Rech Med | Proteines c modifiees activables directement par la thrombine |
| FR2841904B1 (fr) | 2002-07-03 | 2004-08-20 | Inst Nat Sante Rech Med | Analogues de facteurs x clivables par la thrombine |
| EP1728798A1 (en) | 2005-06-01 | 2006-12-06 | ZLB Behring GmbH | Coagulation factor X polypeptides with modified activation properties |
| EP1820508A1 (en) | 2006-02-21 | 2007-08-22 | CSL Behring GmbH | Coagulation factor X polypeptides with modified activation properties |
| EP2193196B1 (en) * | 2007-09-28 | 2016-07-13 | Portola Pharmaceuticals, Inc. | Antidotes for factor xa inhibitors and methods of using the same |
| PL2300497T3 (pl) | 2008-06-24 | 2013-02-28 | Octapharma Ag | Sposób oczyszczania czynnika krzepnięcia VIII |
| EP2364165B1 (en) | 2008-11-14 | 2018-01-03 | Portola Pharmaceuticals, Inc. | Antidotes for factor xa inhibitors and methods of using the same in combination with blood coagulating agents |
| ES2629099T3 (es) | 2008-12-19 | 2017-08-07 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Derivados de serin proteasa y usos en la prevención o el tratamiento de y trastornos de la coagulación sanguinea |
| JP6163304B2 (ja) | 2009-07-15 | 2017-07-12 | ポートラ ファーマシューティカルズ， インコーポレイテッド | 第Ｘａ因子インヒビターの解毒剤の単位用量処方物およびその使用方法 |
| HRP20191305T1 (hr) * | 2010-07-09 | 2019-10-18 | Bioverativ Therapeutics Inc. | Preradive jednolančane molekule i polipeptidi izrađeni koristeći iste |
| FR2972114B1 (fr) | 2011-03-01 | 2013-03-15 | Univ Grenoble 1 | Un nouveau leurre moleculaire procoagulant pour le traitement des hemophiles a ou b avec ou sans inhibiteur |
| SG11201500579SA (en) | 2012-07-25 | 2015-02-27 | Catalyst Biosciences Inc | Modified factor x polypeptides and uses thereof |
| KR20150103205A (ko) | 2013-01-31 | 2015-09-09 | 화이자 인코포레이티드 | 인자 Xa 억제를 길항하기 위한 조성물 및 방법 |
| SG11201601221XA (en) | 2013-09-24 | 2016-04-28 | Pfizer | Compositions comprising heterogeneous populations of recombinant human clotting factor xa proteins |
| CA2928762A1 (en) | 2013-11-01 | 2015-05-07 | The Children's Hospital Of Philadelphia | Compositions and methods for increasing the half-life of factor xa |
| CA2937418A1 (en) | 2014-01-24 | 2015-07-30 | Pfizer Inc. | Compositions and methods for treating intracerebral hemorrhage |
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2014
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- 2014-09-16 WO PCT/IB2014/064564 patent/WO2015044836A1/en not_active Ceased
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- 2014-09-16 MX MX2016003871A patent/MX373466B/es active IP Right Grant
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| US20090175931A1 (en) * | 2005-11-15 | 2009-07-09 | Camire Rodney M | Compositions and methods for modulating hemostasis |
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| BR112016005899A8 (pt) | 2018-02-06 |
| US20170333535A1 (en) | 2017-11-23 |
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| US9757434B2 (en) | 2017-09-12 |
| MX2016003871A (es) | 2016-08-04 |
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| US20210106658A1 (en) | 2021-04-15 |
| IL244258A0 (en) | 2016-04-21 |
| AR097732A1 (es) | 2016-04-13 |
| TWI631134B (zh) | 2018-08-01 |
| CN105579468A (zh) | 2016-05-11 |
| AU2014326257A1 (en) | 2016-03-10 |
| BR112016005899A2 (pt) | 2017-09-26 |
| CA2924981A1 (en) | 2015-04-02 |
| MX373466B (es) | 2020-05-25 |
| KR20160044034A (ko) | 2016-04-22 |
| SG11201601221XA (en) | 2016-04-28 |
| CA2924981C (en) | 2020-03-31 |
| SA516370751B1 (ar) | 2018-04-05 |
| JP6429885B2 (ja) | 2018-11-28 |
| JP2016535071A (ja) | 2016-11-10 |
| IL279396A (en) | 2021-01-31 |
| US10660946B2 (en) | 2020-05-26 |
| KR101988705B1 (ko) | 2019-06-12 |
| PE20160877A1 (es) | 2016-09-11 |
| WO2015044836A1 (en) | 2015-04-02 |
| RU2016108608A (ru) | 2017-10-26 |
| AU2014326257B2 (en) | 2017-08-10 |
| TW201524996A (zh) | 2015-07-01 |
| CN112195169A (zh) | 2021-01-08 |
| HK1218760A1 (zh) | 2017-03-10 |
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