RU2644346C2 - Система полицистронной экспрессии для бактерий - Google Patents

Система полицистронной экспрессии для бактерий Download PDF

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RU2644346C2
RU2644346C2 RU2013157300A RU2013157300A RU2644346C2 RU 2644346 C2 RU2644346 C2 RU 2644346C2 RU 2013157300 A RU2013157300 A RU 2013157300A RU 2013157300 A RU2013157300 A RU 2013157300A RU 2644346 C2 RU2644346 C2 RU 2644346C2
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promoter
gene
lactic acid
genes
endogenous
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RU2013157300A (ru
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Клаас ВАНДЕНБРОУКЕ
ХЮНЕГЕМ Каролин ВАН
Лотхар СТЕЙДЛЕР
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Интрексон Актобиотикс Н.В.
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    • C12N15/746—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for lactic acid bacteria (Streptococcus; Lactococcus; Lactobacillus; Pediococcus; Enterococcus; Leuconostoc; Propionibacterium; Bifidobacterium; Sporolactobacillus)
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RU2013157300A 2011-06-01 2012-06-01 Система полицистронной экспрессии для бактерий RU2644346C2 (ru)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP11168495.7 2011-06-01
EP11168495 2011-06-01
EP11173588.2 2011-07-12
EP11173588 2011-07-12
PCT/EP2012/060431 WO2012164083A1 (en) 2011-06-01 2012-06-01 Polycistronic expression system for bacteria

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RU2013157300A RU2013157300A (ru) 2015-07-20
RU2644346C2 true RU2644346C2 (ru) 2018-02-08

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RU2018102374A RU2766157C2 (ru) 2011-06-01 2012-06-01 Система полицистронной экспрессии для бактерий

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US (3) US9920324B2 (https=)
EP (2) EP3360967B1 (https=)
JP (3) JP6175428B2 (https=)
KR (1) KR102066292B1 (https=)
CN (2) CN103562390B (https=)
AU (2) AU2012264589B2 (https=)
BR (1) BR112013030824A8 (https=)
CA (2) CA3136084A1 (https=)
DK (1) DK2714912T3 (https=)
ES (1) ES2676877T3 (https=)
HU (1) HUE039577T2 (https=)
RU (2) RU2644346C2 (https=)
WO (1) WO2012164083A1 (https=)

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US10676723B2 (en) 2015-05-11 2020-06-09 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US10905727B2 (en) 2016-01-14 2021-02-02 Intrexon Actobiotics N.V. Compositions and methods for the treatment of type 1 diabetes
CN118813511A (zh) 2016-09-02 2024-10-22 英特瑞克斯顿阿克图比奥帝克斯有限公司 稳定表达il-10和胰岛素的遗传修饰的细菌
RU2021135949A (ru) 2016-09-13 2022-04-14 Интрексон Актобиотикс Н.В. Мукоадгезивный микроорганизм
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
US11541105B2 (en) 2018-06-01 2023-01-03 The Research Foundation For The State University Of New York Compositions and methods for disrupting biofilm formation and maintenance
GB201906775D0 (en) * 2019-05-14 2019-06-26 Res & Innovation Uk Synthetic genome
CA3156035A1 (en) 2019-09-27 2021-04-01 Intrexon Actobiotics Nv D/B/A Precigen Actobio Treatment of celiac disease
WO2024003873A1 (en) 2022-06-30 2024-01-04 Intrexon Actobiotics Nv D/B/A Precigen Actobio Single variable domain antibodies against tumor necrosis factor-alpha

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