RU2562868C2 - Двойной вектор для подавления вируса иммунодефицита человека - Google Patents

Двойной вектор для подавления вируса иммунодефицита человека Download PDF

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RU2562868C2
RU2562868C2 RU2012105281/10A RU2012105281A RU2562868C2 RU 2562868 C2 RU2562868 C2 RU 2562868C2 RU 2012105281/10 A RU2012105281/10 A RU 2012105281/10A RU 2012105281 A RU2012105281 A RU 2012105281A RU 2562868 C2 RU2562868 C2 RU 2562868C2
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hiv
cells
nucleic acid
protein
expression vector
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RU2012105281/10A
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Russian (ru)
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RU2012105281A (ru
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Ирвин ЧЕН
Дон Сунн ЭН
Мишель МИЛЛИНГТОН
Маурин БОЙД
Джеффри П. САЙМОНДС
Луис Рэндол БРЕТОН
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Кэлиммьюн Инк.
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
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    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
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    • A61K38/162—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from virus
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    • A61K48/0058—Nucleic acids adapted for tissue specific expression, e.g. having tissue specific promoters as part of a contruct
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    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
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    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
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    • A01K2267/00—Animals characterised by purpose
    • A01K2267/03—Animal model, e.g. for test or diseases
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    • A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
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    • C07K2319/00—Fusion polypeptide
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    • C12N2310/53—Physical structure partially self-complementary or closed
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RU2012105281/10A 2009-07-15 2010-05-26 Двойной вектор для подавления вируса иммунодефицита человека RU2562868C2 (ru)

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US22568709P 2009-07-15 2009-07-15
US61/225,687 2009-07-15
US28759909P 2009-12-17 2009-12-17
US61/287,599 2009-12-17
PCT/US2010/036247 WO2011008348A2 (en) 2009-07-15 2010-05-26 Dual vector for inhibition of human immunodeficiency virus

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RU2012105281A RU2012105281A (ru) 2013-08-20
RU2562868C2 true RU2562868C2 (ru) 2015-09-10

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RU2015133046A RU2015133046A (ru) 2009-07-15 2010-05-26 Двойной вектор для подавления вируса иммунодефицита человека

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US (3) US20120201794A1 (enExample)
EP (4) EP3659435A1 (enExample)
JP (4) JP5828838B2 (enExample)
AU (1) AU2010274031B2 (enExample)
CA (1) CA2767972A1 (enExample)
DK (2) DK3329772T3 (enExample)
ES (3) ES2657737T3 (enExample)
RU (2) RU2562868C2 (enExample)
WO (1) WO2011008348A2 (enExample)

Cited By (6)

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RU2768032C1 (ru) * 2021-09-02 2022-03-23 Федеральное бюджетное учреждение науки "Государственный научный центр вирусологии и биотехнологии "Вектор" Федеральной службы по надзору в сфере защиты прав потребителей и благополучия человека (ФБУН ГНЦ ВБ "Вектор" Роспотребнадзора) Генетическая конструкция для экспрессии генов mNG_CD4-CXCR4, рекомбинантная плазмида rVSV_mNG_CD4-CXCR4 и рекомбинантный штамм вируса везикулярного стоматита rVSV_mNG_CD4-CXCR4, обеспечивающий таргетный виролизис клеток, экспонирующих на своей поверхности белки gp120/gp 41 ВИЧ-1 тропности X4
RU2769125C1 (ru) * 2021-09-02 2022-03-28 Федеральное бюджетное учреждение науки "Государственный научный центр вирусологии и биотехнологии "Вектор" Федеральной службы по надзору в сфере защиты прав потребителей и благополучия человека (ФБУН ГНЦ ВБ "Вектор" Роспотребнадзора) Генетическая конструкция для экспрессии генов mNG_CD4-CCR5, рекомбинантная плазмида rVSV_mNG_CD4-CCR5 и рекомбинантный штамм вируса везикулярного стоматита rVSV_mNG_CD4-CCR5, обеспечивающий таргетный виролизис клеток, экспонирующих на своей поверхности белки gp120/gp41 ВИЧ-1 тропности R5

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