RU2543325C2 - Применение аллопуринола для лечения ладонно-подошвенного синдрома - Google Patents

Применение аллопуринола для лечения ладонно-подошвенного синдрома Download PDF

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Publication number
RU2543325C2
RU2543325C2 RU2011148355/15A RU2011148355A RU2543325C2 RU 2543325 C2 RU2543325 C2 RU 2543325C2 RU 2011148355/15 A RU2011148355/15 A RU 2011148355/15A RU 2011148355 A RU2011148355 A RU 2011148355A RU 2543325 C2 RU2543325 C2 RU 2543325C2
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Russia
Prior art keywords
allopurinol
lps
palmar
drug
treatment
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RU2011148355/15A
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English (en)
Russian (ru)
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RU2011148355A (ru
Inventor
Иоланда РОДЕМЕР
Original Assignee
Нобера Фарма, С.Л.
Эдванселл Эдванст Ин Витро Селл Текнолоджис, С.А.
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/12—Keratolytics, e.g. wart or anti-corn preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Toxicology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
RU2011148355/15A 2009-04-29 2010-04-29 Применение аллопуринола для лечения ладонно-подошвенного синдрома RU2543325C2 (ru)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US21489409P 2009-04-29 2009-04-29
US61/214,894 2009-04-29
EP09382058A EP2246057A1 (en) 2009-04-29 2009-04-29 Use of allopurinol for the treatment of hand foot skin reaction
EP09382058.7 2009-04-29
PCT/EP2010/055806 WO2010125143A1 (en) 2009-04-29 2010-04-29 Use of allopurinol for the treatment of hand foot skin reaction

Publications (2)

Publication Number Publication Date
RU2011148355A RU2011148355A (ru) 2013-06-10
RU2543325C2 true RU2543325C2 (ru) 2015-02-27

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
RU2011148355/15A RU2543325C2 (ru) 2009-04-29 2010-04-29 Применение аллопуринола для лечения ладонно-подошвенного синдрома

Country Status (22)

Country Link
US (2) US8623878B2 (enExample)
EP (2) EP2246057A1 (enExample)
JP (1) JP6007101B2 (enExample)
KR (1) KR20120049848A (enExample)
CN (1) CN102421436B (enExample)
AR (1) AR076505A1 (enExample)
AU (2) AU2010243594A1 (enExample)
BR (1) BRPI1011971A2 (enExample)
CA (1) CA2759085C (enExample)
DK (1) DK2424538T3 (enExample)
ES (1) ES2434366T3 (enExample)
HR (1) HRP20131070T1 (enExample)
IL (1) IL215831A (enExample)
ME (1) ME01567B (enExample)
MX (1) MX2011011529A (enExample)
NZ (1) NZ595901A (enExample)
PL (1) PL2424538T3 (enExample)
PT (1) PT2424538E (enExample)
RS (1) RS53005B (enExample)
RU (1) RU2543325C2 (enExample)
SI (1) SI2424538T1 (enExample)
WO (1) WO2010125143A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2846440C1 (ru) * 2025-01-16 2025-09-05 Общество с ограниченной ответственностью "Мир-Фарм" Средство для профилактики и лечения ладонно-подошвенного синдрома

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AU2010306671B2 (en) 2009-10-16 2015-12-17 Duke University Compositions and methods for the treatment of drug-induced hand-foot syndrome
CA2824933A1 (en) * 2011-01-18 2012-07-26 Vicus Therapeutics, Llc Pharmaceutical compositions and methods for making and using them
CA3085013A1 (en) 2017-12-13 2019-06-20 Onquality Pharmaceuticals China Ltd. A method for preventing or treating egfr-inhibition associated diseases
CN113975264A (zh) * 2018-04-16 2022-01-28 上海岸阔医药科技有限公司 预防或治疗肿瘤疗法副作用的方法
US20200046703A1 (en) * 2018-08-09 2020-02-13 Asymmetric Therapeutics, Llc Compositions and methods for treatment of the side-effects associated with administration of therapeutic agents
US20250114362A1 (en) 2022-01-05 2025-04-10 Asymmetric Therapeutics, Llc Methods and compositions for treatment of cutaneous proliferative disorders and other skin conditions
KR20250056445A (ko) * 2023-10-19 2025-04-28 (주) 수파드엘릭사 수족증후군 또는 수족피부반응의 예방 또는 치료용 약학 조성물

Citations (1)

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WO1994005293A1 (en) * 1992-09-04 1994-03-17 Aws Shakir Mustafa Salim Skin treatment compositions containing dimethylsulphone and allopurinol or oxypurinol

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WO1994005293A1 (en) * 1992-09-04 1994-03-17 Aws Shakir Mustafa Salim Skin treatment compositions containing dimethylsulphone and allopurinol or oxypurinol

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Robert C et. all. ";Dermotologic symptoms associated with the multikinase inhibitor sorafenib";, J Am Acad Dermatol. 2009 Feb;60(2):299-305. doi: 10.1016/j.jaad.2008.06.034. Epub 2008 Nov 25., найдено в PubMed PMID:19028406. Rosenbaum SE, et. all. ";Dermatological reactions to the multitargeted tyrosine kinase inhibitor sunitinib.";, Support Care Cancer. 2008 Jun;16(6):557-66. doi: 10.1007/s00520-008-0409-1. Epub 2008 Feb 15., найдено в PubMed PMID:18274784. М.М. Хобейш, К.Н. Монахов Дайвобет - новый высокоэффективный препарат для наружного лечения ладонно-подошвенного псориаза. КЛИНИЧЕСКАЯ ДЕРМАТОЛОГИЯ 1, 2008, Найденов Интернет на сайте: http://medi.ru/doc/a795804.htm *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2846440C1 (ru) * 2025-01-16 2025-09-05 Общество с ограниченной ответственностью "Мир-Фарм" Средство для профилактики и лечения ладонно-подошвенного синдрома

Also Published As

Publication number Publication date
CN102421436B (zh) 2014-05-07
US20100280051A1 (en) 2010-11-04
RS53005B (sr) 2014-04-30
US20140080845A1 (en) 2014-03-20
PL2424538T3 (pl) 2014-05-30
DK2424538T3 (da) 2013-11-04
KR20120049848A (ko) 2012-05-17
IL215831A0 (en) 2012-01-31
CA2759085C (en) 2016-08-16
EP2246057A1 (en) 2010-11-03
ES2434366T3 (es) 2013-12-16
PT2424538E (pt) 2013-11-07
RU2011148355A (ru) 2013-06-10
NZ595901A (en) 2013-11-29
ME01567B (me) 2014-04-20
EP2424538B1 (en) 2013-08-14
US8623878B2 (en) 2014-01-07
WO2010125143A1 (en) 2010-11-04
CA2759085A1 (en) 2010-11-04
AU2016228193A1 (en) 2016-11-03
JP6007101B2 (ja) 2016-10-12
HK1168042A1 (en) 2012-12-21
MX2011011529A (es) 2012-02-08
SI2424538T1 (sl) 2013-12-31
BRPI1011971A2 (pt) 2016-04-26
IL215831A (en) 2016-02-29
CN102421436A (zh) 2012-04-18
HRP20131070T1 (hr) 2013-12-20
EP2424538A1 (en) 2012-03-07
AR076505A1 (es) 2011-06-15
AU2010243594A1 (en) 2011-11-10
JP2012525358A (ja) 2012-10-22

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Effective date: 20170430