RU2540077C2 - Синтетические миметики иммунной защиты и их применение - Google Patents
Синтетические миметики иммунной защиты и их применение Download PDFInfo
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- RU2540077C2 RU2540077C2 RU2011121354/04A RU2011121354A RU2540077C2 RU 2540077 C2 RU2540077 C2 RU 2540077C2 RU 2011121354/04 A RU2011121354/04 A RU 2011121354/04A RU 2011121354 A RU2011121354 A RU 2011121354A RU 2540077 C2 RU2540077 C2 RU 2540077C2
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- butoxycarbonyl
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Classifications
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- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
- C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
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- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
Landscapes
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- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
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- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10859508P | 2008-10-27 | 2008-10-27 | |
| US61/108,595 | 2008-10-27 | ||
| US12/605,584 US8278309B2 (en) | 2008-10-27 | 2009-10-26 | Synthetic mimetics of host defense and uses thereof |
| US12/605,584 | 2009-10-26 | ||
| PCT/US2009/062147 WO2010062573A1 (en) | 2008-10-27 | 2009-10-27 | Synthetic mimetics of host defense and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2011121354A RU2011121354A (ru) | 2012-12-10 |
| RU2540077C2 true RU2540077C2 (ru) | 2015-01-27 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2011121354/04A RU2540077C2 (ru) | 2008-10-27 | 2009-10-27 | Синтетические миметики иммунной защиты и их применение |
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| Country | Link |
|---|---|
| US (2) | US8278309B2 (OSRAM) |
| EP (1) | EP2358380A4 (OSRAM) |
| JP (1) | JP2012506908A (OSRAM) |
| KR (1) | KR20110074995A (OSRAM) |
| CN (1) | CN102256614B (OSRAM) |
| AU (1) | AU2009320139B2 (OSRAM) |
| BR (1) | BRPI0920251A2 (OSRAM) |
| CA (1) | CA2741764A1 (OSRAM) |
| IL (1) | IL212275A0 (OSRAM) |
| MX (1) | MX2011004360A (OSRAM) |
| RU (1) | RU2540077C2 (OSRAM) |
| TW (1) | TWI478915B (OSRAM) |
| UA (1) | UA104875C2 (OSRAM) |
| WO (1) | WO2010062573A1 (OSRAM) |
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| RU2606128C2 (ru) * | 2011-05-16 | 2017-01-10 | Селлсьютикс Корпорейшн | Соединения для применения в лечении мукозита |
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| US20090092574A1 (en) * | 2006-12-29 | 2009-04-09 | Scott Richard W | Ophthalmic And Otic Compositions Of Facially Amphiphilic Polymers And Oligomers And Uses Thereof |
| US8278309B2 (en) * | 2008-10-27 | 2012-10-02 | Polymedix, Inc. | Synthetic mimetics of host defense and uses thereof |
| US9758607B2 (en) | 2013-10-10 | 2017-09-12 | Research Foundation Of The City University Of New York | Polymer with antibacterial activity |
| JP6047203B2 (ja) * | 2015-02-20 | 2016-12-21 | セルセウティックス コーポレイション | 消化管の炎症性疾患の予防および／または治療のための宿主防御タンパク質（ｈｄｐ）模倣薬 |
| CN107574581B (zh) * | 2017-08-03 | 2019-09-10 | 天津大学 | 一种抗菌性聚(ε-己内酯)/模拟抗菌肽电纺纤维膜及其制备方法 |
| US20230218644A1 (en) | 2020-04-16 | 2023-07-13 | Som Innovation Biotech, S.A. | Compounds for use in the treatment of viral infections by respiratory syndrome-related coronavirus |
| US11771694B2 (en) | 2020-06-05 | 2023-10-03 | Innovation Pharmaceuticals Inc. | Arylamide compounds for treatment and prevention of viral infections |
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| RU2325151C2 (ru) * | 2006-06-29 | 2008-05-27 | ООО "Научно-производственный центр "Амфион" | Способ получения системы доставки водонерастворимых и плохорастворимых биологически активных веществ и лекарственная форма на ее основе |
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| JP2005529604A (ja) | 2002-06-13 | 2005-10-06 | ザ・トラスティーズ・オブ・ザ・ユニバーシティ・オブ・ペンシルベニア | 粗粒度モデルを用いる生体膜をシミュレートするための方法、システム、およびコンピュータプログラム製品 |
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Patent Citations (1)
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| RU2325151C2 (ru) * | 2006-06-29 | 2008-05-27 | ООО "Научно-производственный центр "Амфион" | Способ получения системы доставки водонерастворимых и плохорастворимых биологически активных веществ и лекарственная форма на ее основе |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| RU2606128C2 (ru) * | 2011-05-16 | 2017-01-10 | Селлсьютикс Корпорейшн | Соединения для применения в лечении мукозита |
| US9795575B2 (en) | 2011-05-16 | 2017-10-24 | Innovation Pharmaceuticals Inc. | Compounds for use in treatment of mucositis |
| US10206894B2 (en) | 2011-05-16 | 2019-02-19 | Innovation Pharmaceuticals Inc. | Compounds for use in treatment of mucositis |
| US10603294B2 (en) | 2011-05-16 | 2020-03-31 | Innovation Pharmaceuticals Inc. | Compounds for use in treatment of mucositis |
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| AU2009320139B2 (en) | 2013-07-25 |
| US20100105703A1 (en) | 2010-04-29 |
| EP2358380A4 (en) | 2012-05-02 |
| WO2010062573A1 (en) | 2010-06-03 |
| US8278309B2 (en) | 2012-10-02 |
| CN102256614B (zh) | 2014-01-08 |
| EP2358380A1 (en) | 2011-08-24 |
| UA104875C2 (uk) | 2014-03-25 |
| IL212275A0 (en) | 2011-06-30 |
| MX2011004360A (es) | 2011-08-12 |
| TWI478915B (zh) | 2015-04-01 |
| BRPI0920251A2 (pt) | 2016-01-05 |
| CN102256614A (zh) | 2011-11-23 |
| RU2011121354A (ru) | 2012-12-10 |
| KR20110074995A (ko) | 2011-07-05 |
| JP2012506908A (ja) | 2012-03-22 |
| US8975262B2 (en) | 2015-03-10 |
| AU2009320139A1 (en) | 2010-06-03 |
| CA2741764A1 (en) | 2010-06-03 |
| US20130090345A1 (en) | 2013-04-11 |
| TW201020249A (en) | 2010-06-01 |
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