RU2539595C2 - Изоксазолины в качестве ингибиторов амидгидролазы жирных кислот - Google Patents

Изоксазолины в качестве ингибиторов амидгидролазы жирных кислот Download PDF

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RU2539595C2
RU2539595C2 RU2011151635/04A RU2011151635A RU2539595C2 RU 2539595 C2 RU2539595 C2 RU 2539595C2 RU 2011151635/04 A RU2011151635/04 A RU 2011151635/04A RU 2011151635 A RU2011151635 A RU 2011151635A RU 2539595 C2 RU2539595 C2 RU 2539595C2
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RU2011151635A (ru
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Марк Л. БЕНКЕ
Альфредо С. КАСТРО
Лоуренс К. ЧАН
Кэтрин А. ЭВАНС
Луи ГРЕНЬЕ
Майкл Дж. ГРОГАН
Ив Леблан
Тао ЛЮ
Стефан ПЕЛЮЗО
Дэниел А. СНАЙДЕР
Томас Т. ТИББИТТС
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Инфинити Фармасьютикалз, Инк.
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    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
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    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D261/04—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
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    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
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    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
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    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Dermatology (AREA)
  • Reproductive Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hematology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Pulmonology (AREA)
  • Endocrinology (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Rheumatology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Ophthalmology & Optometry (AREA)
  • Gynecology & Obstetrics (AREA)
  • Vascular Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
RU2011151635/04A 2009-05-18 2010-05-18 Изоксазолины в качестве ингибиторов амидгидролазы жирных кислот RU2539595C2 (ru)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US17928509P 2009-05-18 2009-05-18
US17928309P 2009-05-18 2009-05-18
US17928009P 2009-05-18 2009-05-18
US61/179,283 2009-05-18
US61/179,285 2009-05-18
US61/179,280 2009-05-18
PCT/US2010/035309 WO2010135360A1 (en) 2009-05-18 2010-05-18 Isoxazolines as inhibitors of fatty acid amide hydrolase

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RU2011151635A RU2011151635A (ru) 2013-06-27
RU2539595C2 true RU2539595C2 (ru) 2015-01-20

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EP (1) EP2432771A4 (cg-RX-API-DMAC7.html)
JP (1) JP2012527467A (cg-RX-API-DMAC7.html)
KR (1) KR20120042766A (cg-RX-API-DMAC7.html)
CN (1) CN102459202B (cg-RX-API-DMAC7.html)
AR (1) AR076687A1 (cg-RX-API-DMAC7.html)
AU (1) AU2010249674A1 (cg-RX-API-DMAC7.html)
BR (1) BRPI1011049A2 (cg-RX-API-DMAC7.html)
CA (1) CA2762527A1 (cg-RX-API-DMAC7.html)
IL (1) IL216420A0 (cg-RX-API-DMAC7.html)
MX (1) MX2011012263A (cg-RX-API-DMAC7.html)
NZ (2) NZ596585A (cg-RX-API-DMAC7.html)
RU (1) RU2539595C2 (cg-RX-API-DMAC7.html)
SG (2) SG10201402443PA (cg-RX-API-DMAC7.html)
TW (1) TW201043620A (cg-RX-API-DMAC7.html)
WO (1) WO2010135360A1 (cg-RX-API-DMAC7.html)
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US10954231B2 (en) 2006-10-16 2021-03-23 Bionomics Limited Anxiolytic compounds
US8927551B2 (en) 2009-05-18 2015-01-06 Infinity Pharmaceuticals, Inc. Isoxazolines as inhibitors of fatty acid amide hydrolase
US9149465B2 (en) 2009-05-18 2015-10-06 Infinity Pharmaceuticals, Inc. Isoxazolines as inhibitors of fatty acid amide hydrolase
WO2011085216A2 (en) 2010-01-08 2011-07-14 Ironwood Pharmaceuticals, Inc. Use of faah inhibitors for treating parkinson's disease and restless legs syndrome
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WO2018112843A1 (en) 2016-12-22 2018-06-28 Merck Sharp & Dohme Corp. Heteroaryl piperidine ether allosteric modulators of the m4 muscarinic acetylcholine receptor
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RU2011151635A (ru) 2013-06-27
BRPI1011049A2 (pt) 2019-09-24
MX2011012263A (es) 2012-01-30
EP2432771A4 (en) 2013-06-05
CN102459202A (zh) 2012-05-16
JP2012527467A (ja) 2012-11-08
IL216420A0 (en) 2012-03-01
SG176168A1 (en) 2011-12-29
CA2762527A1 (en) 2010-11-25
CN102459202B (zh) 2015-11-25
TW201043620A (en) 2010-12-16
EP2432771A1 (en) 2012-03-28
AR076687A1 (es) 2011-06-29
WO2010135360A1 (en) 2010-11-25
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KR20120042766A (ko) 2012-05-03
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