RU2524643C1 - Method of preparing anti-inflammatory veterinary ointment - Google Patents

Abstract

FIELD: veterinary medicine.

SUBSTANCE: method of preparing the anti-inflammatory veterinary ointment for outward application consists in mixing while heating to the temperature of 40-50°C in the reactor of molten petrolatum, pine oleoresin, chlorophyll-carotene paste until homogenous consistency, then glycerine and olive oil is fed portionwise with continuous stirring, after which again mixing of the components is carried out for 10-30 minutes until the homogeneous mass, the resulting ointment is cooled and packaged, at that the components of the mixture are taken in the following ratio, wt %: pine oleoresin 3.0; chlorophyll-carotene paste 3.0; petrolatum 69.0; glycerine 5.0; olive oil 20.0.

EFFECT: improved efficacy of treatment.

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Description

The invention relates to veterinary medicine, in particular to a technology for producing anti-inflammatory veterinary ointment for the treatment of mastitis, burns, eczema, tissue damage, cracks.

Known methods for the preparation of ointments, including mixing medicinal or biologically active substances with the fat base of the ointment [Handbook, ed. I.E. Mozgova. Veterinary recipe with the basics of therapy and prevention. M. VO "Agropromizdat", 1988 (1)].

The known composition of the anti-inflammatory ointment for external use "Pichtoin", including pine resin, 19.0-21.0%, beeswax 16.8-17.5%, chalk 10.5-12.0%, the rest is fat [Patent RU 2097056 publ. 1997.11.27 (2)]. However, the method of its preparation is laborious and ineffective; the presence of chalk negatively affects the technology for the preparation and use of ointments based on it.

The aim of the invention is to develop the most effective, more productive technology for the production of anti-inflammatory veterinary ointments, which allows to increase the homogeneity, the main quality of the obtained ointment.

A method of preparing an anti-inflammatory veterinary ointment for external use consists in mixing, when heated to a temperature of 40-50 ° C, in a reactor molten petroleum jelly, pine resin, chlorophyll-carotene paste to a homogeneous consistency, then glycerin and olive oil are portioned with constant stirring, after which again again the components are mixed for 10-30 minutes to a homogeneous mass, then cooled and packaged, while the components of the mixture are taken in the following ratio, wt.%:

Zhivitsa pine 3.0 Chlorophyll-carotene paste 3.0 Petroleum jelly 69.0 Glycerol 5,0 Olive oil 20,0

Zhivitsa pine gives the antiseptic properties of the ointment, goes well with the components. After application to the wound and drying forms an antiseptic film.

Coniferous chlorophyll-carotene paste due to the presence in its composition of natural compounds that stimulate the healing of affected areas, and powerful antioxidants cleans the wound from dead tissue, has an anti-inflammatory effect, protects against external pathogenic microorganisms, and stimulates repair processes.

Petroleum jelly and glycerin adhere to the skin and pile (wool, bristles, etc.). It forms a protective thin layer on the surface of the wound (burn), permeable to air and resistant to moisture.

Olive oil contains a complex of vitamins: E and A are responsible for moisturizing and elasticity of the skin; B, D, K, as well as monounsaturated fats affect the improvement of the skin condition and help accelerate the regeneration of skin cells and give the oil a healing effect.

Anti-inflammatory veterinary ointment is a homogeneous mass of light yellow in color with the smell of needles. When applied to the skin, the ointment penetrates through the sebaceous glands and partially through the intercellular passages, where it passes into a soluble state and is gradually absorbed, helping to dilate blood vessels, improve blood circulation and accelerate the resolution of hematomas.

Veterinary ointment is used to treat farm animals with mastitis, wounds, burns, traumatic tissue injuries, eczema, dermatitis, bursitis, bruises, with papillomas and ulcers on the nipples of the udder.

The ointment is applied in a thin layer on a clean white cloth or gauze, which covers the affected area of the body, and then strengthened with a bandage or special glue. With bruises, mastitis, a warming dressing is applied.

Example 1. In a reactor equipped with a jacket and a mixing device, 13.8 kg of petroleum jelly are fed, it is melted and 0.6 kg of pine resin, previously purified from mechanical impurities and water, 0.6 kg of chlorophyll-carotene paste are added. The ingredients are heated to a temperature of 40-50 ° C, stirred until a homogeneous consistency, then 1.0 kg of glycerin and 4.0 kg of olive oil are slowly fed. After loading all the ingredients, the mixture is stirred until homogeneous for 10-30 minutes. The resulting ointment is cooled and packaged.

Example 2. In a reactor equipped with a jacket and a mixing device, 13.8 kg of petroleum jelly are fed, it is melted and 0.6 kg of pine resin, previously purified from mechanical impurities and water, 0.6 kg of chlorophyll-carotene paste are added. The ingredients are heated to a temperature of 40-50 ° C, stirred until a homogeneous consistency, then 1.0 kg of glycerin and 4.0 kg of olive oil are slowly fed. After loading all the ingredients, the mixture is stirred until homogeneous for 10-40 minutes. The resulting ointment is cooled and packaged.

A study of veterinary ointment was carried out at the Department of Veterinary Pathology of the Agrarian Institute of the Mordovian State University named after N.P. Ogareva ”, Saransk, preliminary results were positive. Experiments on the treatment of wounds using an ointment based on the proposed composition showed the following results: in different animals, clinical signs of the disease are expressed to varying degrees, which is explained by the nature of the wound microflora and the reaction of the animal tissues. The boundaries of individual tissues and their anatomical structure are masked by fibrin mixed with blood residues. By 5-7 days, in certain areas free of blood clots, pink-red nodules the size of millet grain that did not bleed appeared, had a granular appearance, rather dense texture, a small amount of grayish-white exudate was noted. By this time, demarcation of non-viable tissues took place, which were then rejected and lysed in the wound. The amount of discharge from the wound quickly decreased, became serous. The use of ointment based on pine gum improved the biochemical parameters of experimental laboratory animals, by the 12th day there was a tendency to normalize metabolic processes.

Studies have shown that the use of an ointment based on the proposed composition provides optimal conditions for the flow of metabolic processes in tissues by affecting local microcirculation, stimulating reparative processes in the wound, as well as preventing secondary infection of the wound, especially microorganisms that have resistance to modern antiseptics.

Information sources

1. Reference, ed. I.E. Mozgova. Veterinary recipe with the basics of therapy and prevention. M .: Agropromizdat, 1988.

2. Patent RU 2097056, publ. 1997.11.27, prototype.

Claims (1)

A method of preparing an anti-inflammatory veterinary ointment for external use, which consists in mixing, when heated to a temperature of 40-50 ° C, in a reactor molten petroleum jelly, pine resin, chlorophyll-carotene paste to a homogeneous consistency, then glycerin and olive oil are portioned with constant stirring, after which again carry out the mixing of the components for 10-30 minutes to a homogeneous mass, the resulting ointment is cooled and packaged, while the components of the mixture are taken in the following ratio ii, wt.%:
Zhivitsa pine 3.0 Chlorophyll-carotene paste 3.0 Petroleum jelly 69.0 Glycerol 5,0 Olive oil 20,0