RU2521333C2 - Способы и композиции для стимулирования нейрогенеза и ингибирования дегенерации нейронов с использованием изотиазолопиримидинонов - Google Patents

Способы и композиции для стимулирования нейрогенеза и ингибирования дегенерации нейронов с использованием изотиазолопиримидинонов Download PDF

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RU2521333C2
RU2521333C2 RU2010100945/15A RU2010100945A RU2521333C2 RU 2521333 C2 RU2521333 C2 RU 2521333C2 RU 2010100945/15 A RU2010100945/15 A RU 2010100945/15A RU 2010100945 A RU2010100945 A RU 2010100945A RU 2521333 C2 RU2521333 C2 RU 2521333C2
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compound
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neurogenesis
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АНДЕРСОН Джудит КЕЛЛЕХЕР
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Ньюронасент, Инк.
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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RU2010100945/15A 2007-06-21 2008-06-20 Способы и композиции для стимулирования нейрогенеза и ингибирования дегенерации нейронов с использованием изотиазолопиримидинонов RU2521333C2 (ru)

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US94552407P 2007-06-21 2007-06-21
US60/945,524 2007-06-21
PCT/US2008/067742 WO2008157791A2 (en) 2007-06-21 2008-06-20 Methods and compositions for stimulating neurogenesis and inhibiting neuronal degeneration using isothiazolopyrimidinones

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RU2010100945A RU2010100945A (ru) 2011-07-27
RU2521333C2 true RU2521333C2 (ru) 2014-06-27

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RU2613765C1 (ru) * 2016-01-26 2017-03-21 Федеральное государственное автономное образовательное учреждение высшего образования "Северо-Восточный федеральный университет им. М.К.Аммосова" Способ лечения спиноцеребеллярной атаксии
RU2670128C2 (ru) * 2016-12-16 2018-10-18 Федеральное государственное автономное образовательное учреждение высшего образования "Балтийский федеральный университет имени Иммануила Канта" (БФУ им. И. Канта) Способ генетической регистрации и коррекции нейрогенеза на основе генетических конструкций для трансфекции нейронов
RU2675111C2 (ru) * 2017-03-31 2018-12-17 Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт фундаментальной и клинической иммунологии" Способ стимуляции нейрогенеза в гиппокампе
RU2756812C2 (ru) * 2016-08-04 2021-10-05 Сайньюрекс Интернэшнл (Тайвань) Корп. Композиции, содержащие бензоатное соединение и дубильную кислоту, для лечения нарушения центральной нервной системы

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EP2170340B1 (en) * 2007-06-21 2016-02-24 Neuronascent, INC. Methods and compositions for stimulating neurogenesis and inhibiting neuronal degeneration using isothiazolopyrimidinones
CA2737219C (en) 2008-08-11 2017-02-28 Tracy Keller Halofuginone analogs for inhibition of trna synthetases and uses thereof
RU2549441C2 (ru) * 2009-09-22 2015-04-27 Ньюронасент, Инк. Способы и фармацевтические композиции для лечения синдрома дауна
CA2861840C (en) 2012-01-13 2020-12-15 President And Fellows Of Harvard College Halofuginol derivatives and their use in cosmetic and pharmaceutical compositions
US9944644B2 (en) 2013-03-14 2018-04-17 The Trustees Of Columbia University In The City Of New York Octahydropyrrolopyrroles their preparation and use
US10273243B2 (en) 2013-03-14 2019-04-30 The Trustees Of Columbia University In The City Of New York 4-phenylpiperidines, their preparation and use
ES2700541T3 (es) 2013-03-14 2019-02-18 Univ Columbia Octahidrociclopentapirroles, su preparación y uso
US9938291B2 (en) 2013-03-14 2018-04-10 The Trustess Of Columbia University In The City Of New York N-alkyl-2-phenoxyethanamines, their preparation and use
WO2015168286A1 (en) 2014-04-30 2015-11-05 The Trustees Of Columbia University In The City Of New York Substituted 4-phenylpiperidines, their preparaiton and use
BR112020000085A2 (pt) * 2017-07-03 2020-07-07 Bayer Cropscience Aktiengesellschaft novos biciclos baseados em isotiazol, processos para sua preparação e seu uso como herbicidas e/ou reguladores de crescimento da planta.
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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2613765C1 (ru) * 2016-01-26 2017-03-21 Федеральное государственное автономное образовательное учреждение высшего образования "Северо-Восточный федеральный университет им. М.К.Аммосова" Способ лечения спиноцеребеллярной атаксии
RU2756812C2 (ru) * 2016-08-04 2021-10-05 Сайньюрекс Интернэшнл (Тайвань) Корп. Композиции, содержащие бензоатное соединение и дубильную кислоту, для лечения нарушения центральной нервной системы
RU2670128C2 (ru) * 2016-12-16 2018-10-18 Федеральное государственное автономное образовательное учреждение высшего образования "Балтийский федеральный университет имени Иммануила Канта" (БФУ им. И. Канта) Способ генетической регистрации и коррекции нейрогенеза на основе генетических конструкций для трансфекции нейронов
RU2675111C2 (ru) * 2017-03-31 2018-12-17 Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт фундаментальной и клинической иммунологии" Способ стимуляции нейрогенеза в гиппокампе

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US20140171428A1 (en) 2014-06-19
AU2008265600B2 (en) 2013-10-31
CN101842100A (zh) 2010-09-22
WO2008157791A2 (en) 2008-12-24
JP2017066166A (ja) 2017-04-06
IL202485A0 (en) 2010-06-30
KR101565971B1 (ko) 2015-11-05
PL2170340T3 (pl) 2016-06-30
JP2014196308A (ja) 2014-10-16
US9096613B2 (en) 2015-08-04
WO2008157791A3 (en) 2009-12-30
US8609840B2 (en) 2013-12-17
AU2008265600A1 (en) 2008-12-24
ES2564826T3 (es) 2016-03-29
RU2010100945A (ru) 2011-07-27
JP6081528B2 (ja) 2017-02-15
EP2170340B1 (en) 2016-02-24
EP2170340A4 (en) 2010-12-08
IL202485A (en) 2017-03-30
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EP3053584A1 (en) 2016-08-10
US9592234B2 (en) 2017-03-14
DK2170340T3 (en) 2016-03-14
IL251169A0 (en) 2017-04-30
JP2010530898A (ja) 2010-09-16
US20160022682A1 (en) 2016-01-28
EP2170340A2 (en) 2010-04-07
KR20150041668A (ko) 2015-04-16
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