RU2488580C2 - Соединения, имеющие арилсульфонамидную структуру, применимые в качестве ингибиторов металлопротеаз - Google Patents
Соединения, имеющие арилсульфонамидную структуру, применимые в качестве ингибиторов металлопротеаз Download PDFInfo
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- RU2488580C2 RU2488580C2 RU2009138346/04A RU2009138346A RU2488580C2 RU 2488580 C2 RU2488580 C2 RU 2488580C2 RU 2009138346/04 A RU2009138346/04 A RU 2009138346/04A RU 2009138346 A RU2009138346 A RU 2009138346A RU 2488580 C2 RU2488580 C2 RU 2488580C2
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
Landscapes
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- Oncology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07104393A EP1972617A1 (en) | 2007-03-19 | 2007-03-19 | Compounds having aryl-sulphonamidic structure useful as metalloproteases inhibitors |
| EP07104393.9 | 2007-03-19 | ||
| PCT/EP2008/053078 WO2008113756A2 (en) | 2007-03-19 | 2008-03-14 | Compounds having aryl-sulphonamidic structure useful as metalloproteases inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2009138346A RU2009138346A (ru) | 2011-04-27 |
| RU2488580C2 true RU2488580C2 (ru) | 2013-07-27 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2009138346/04A RU2488580C2 (ru) | 2007-03-19 | 2008-03-14 | Соединения, имеющие арилсульфонамидную структуру, применимые в качестве ингибиторов металлопротеаз |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US8329751B2 (enExample) |
| EP (2) | EP1972617A1 (enExample) |
| JP (1) | JP2010521529A (enExample) |
| KR (1) | KR20090121329A (enExample) |
| CN (1) | CN101610997A (enExample) |
| AU (1) | AU2008228260B2 (enExample) |
| CA (1) | CA2680239A1 (enExample) |
| IL (1) | IL200951A0 (enExample) |
| MX (1) | MX2009009409A (enExample) |
| RU (1) | RU2488580C2 (enExample) |
| WO (1) | WO2008113756A2 (enExample) |
| ZA (1) | ZA200905263B (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2149568A1 (en) | 2008-07-22 | 2010-02-03 | Bracco Imaging S.p.A | Aryl-sulphonamidic dimers as metalloproteases inhibitors |
| EP2147684A1 (en) * | 2008-07-22 | 2010-01-27 | Bracco Imaging S.p.A | Diagnostic Agents Selective Against Metalloproteases |
| US20240207415A1 (en) | 2022-11-08 | 2024-06-27 | Montelino Therapeutics, Inc. | Bi-functional compounds and methods for targeted ubiquitination of androgen receptor |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2208609C2 (ru) * | 1998-02-04 | 2003-07-20 | Новартис Аг | Сульфониламинопроизводные, которые ингибируют разлагающие матрикс металлопротеиназы |
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| JPS5058026A (enExample) * | 1973-09-26 | 1975-05-20 | ||
| HUP0102196A3 (en) * | 1998-04-03 | 2002-12-28 | Sankyo Company Ltd Chuo Ku | Sulfonamide derivatives |
| WO2006101828A1 (en) * | 2005-03-15 | 2006-09-28 | Bayer Cropscience Ag | Insecticidal alkylamino phenyl sulfonamide derivatives |
-
2007
- 2007-03-19 EP EP07104393A patent/EP1972617A1/en not_active Withdrawn
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2008
- 2008-03-14 KR KR1020097019222A patent/KR20090121329A/ko not_active Ceased
- 2008-03-14 RU RU2009138346/04A patent/RU2488580C2/ru not_active IP Right Cessation
- 2008-03-14 CN CNA200880004727XA patent/CN101610997A/zh active Pending
- 2008-03-14 EP EP08717820A patent/EP2121590A2/en not_active Withdrawn
- 2008-03-14 MX MX2009009409A patent/MX2009009409A/es active IP Right Grant
- 2008-03-14 WO PCT/EP2008/053078 patent/WO2008113756A2/en not_active Ceased
- 2008-03-14 JP JP2010500190A patent/JP2010521529A/ja active Pending
- 2008-03-14 CA CA002680239A patent/CA2680239A1/en not_active Abandoned
- 2008-03-14 AU AU2008228260A patent/AU2008228260B2/en not_active Ceased
- 2008-03-14 US US12/531,119 patent/US8329751B2/en not_active Expired - Fee Related
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2009
- 2009-07-05 ZA ZA200905263A patent/ZA200905263B/xx unknown
- 2009-09-15 IL IL200951A patent/IL200951A0/en unknown
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2208609C2 (ru) * | 1998-02-04 | 2003-07-20 | Новартис Аг | Сульфониламинопроизводные, которые ингибируют разлагающие матрикс металлопротеиназы |
Non-Patent Citations (1)
| Title |
|---|
| Armando Rossello et al.: "A new development of matrix metalloproteinase inhibitors: twin hydroxamic acids as potent inhibitors of MMP", Bioorganic & Medicinal Chemistry Letters, 2005, vol.15, p.2311-2314. Armando Rossello et al.: "N-i-Propoxy-N-biphenylsulfonylaminobutylhydroxamic acids as potent and selective inhibitors of ММР-2 and MT1-MMP", Bioorganic & Medicinal Chemistry Letters, 2005, vol.15, p.1321-1326. * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2008113756A2 (en) | 2008-09-25 |
| CN101610997A (zh) | 2009-12-23 |
| WO2008113756A8 (en) | 2008-11-06 |
| ZA200905263B (en) | 2010-06-30 |
| US8329751B2 (en) | 2012-12-11 |
| RU2009138346A (ru) | 2011-04-27 |
| CA2680239A1 (en) | 2008-09-25 |
| WO2008113756A3 (en) | 2008-12-18 |
| EP1972617A1 (en) | 2008-09-24 |
| US20100087505A1 (en) | 2010-04-08 |
| AU2008228260A1 (en) | 2008-09-25 |
| EP2121590A2 (en) | 2009-11-25 |
| MX2009009409A (es) | 2009-09-14 |
| JP2010521529A (ja) | 2010-06-24 |
| IL200951A0 (en) | 2010-05-17 |
| KR20090121329A (ko) | 2009-11-25 |
| AU2008228260B2 (en) | 2012-11-22 |
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| Date | Code | Title | Description |
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| MM4A | The patent is invalid due to non-payment of fees |
Effective date: 20140315 |