KR20090121329A - 메탈로프로테아제 억제제로서 유용한 아릴-술폰아미드 구조를 갖는 화합물 - Google Patents
메탈로프로테아제 억제제로서 유용한 아릴-술폰아미드 구조를 갖는 화합물 Download PDFInfo
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- KR20090121329A KR20090121329A KR1020097019222A KR20097019222A KR20090121329A KR 20090121329 A KR20090121329 A KR 20090121329A KR 1020097019222 A KR1020097019222 A KR 1020097019222A KR 20097019222 A KR20097019222 A KR 20097019222A KR 20090121329 A KR20090121329 A KR 20090121329A
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/48—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups having nitrogen atoms of sulfonamide groups further bound to another hetero atom
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/18—Sulfonamides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
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- A—HUMAN NECESSITIES
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- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P37/02—Immunomodulators
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Cardiology (AREA)
- Immunology (AREA)
- Heart & Thoracic Surgery (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Hospice & Palliative Care (AREA)
- Physical Education & Sports Medicine (AREA)
- Psychiatry (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Vascular Medicine (AREA)
- Pulmonology (AREA)
- Urology & Nephrology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07104393.9 | 2007-03-19 | ||
| EP07104393A EP1972617A1 (en) | 2007-03-19 | 2007-03-19 | Compounds having aryl-sulphonamidic structure useful as metalloproteases inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20090121329A true KR20090121329A (ko) | 2009-11-25 |
Family
ID=38626433
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020097019222A Ceased KR20090121329A (ko) | 2007-03-19 | 2008-03-14 | 메탈로프로테아제 억제제로서 유용한 아릴-술폰아미드 구조를 갖는 화합물 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US8329751B2 (enExample) |
| EP (2) | EP1972617A1 (enExample) |
| JP (1) | JP2010521529A (enExample) |
| KR (1) | KR20090121329A (enExample) |
| CN (1) | CN101610997A (enExample) |
| AU (1) | AU2008228260B2 (enExample) |
| CA (1) | CA2680239A1 (enExample) |
| IL (1) | IL200951A0 (enExample) |
| MX (1) | MX2009009409A (enExample) |
| RU (1) | RU2488580C2 (enExample) |
| WO (1) | WO2008113756A2 (enExample) |
| ZA (1) | ZA200905263B (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2149568A1 (en) | 2008-07-22 | 2010-02-03 | Bracco Imaging S.p.A | Aryl-sulphonamidic dimers as metalloproteases inhibitors |
| EP2147684A1 (en) | 2008-07-22 | 2010-01-27 | Bracco Imaging S.p.A | Diagnostic Agents Selective Against Metalloproteases |
| WO2024102810A1 (en) | 2022-11-08 | 2024-05-16 | Montelino Therapeutics, Inc. | Bi-functional compounds and methods for targeted ubiquitination of androgen receptor |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5058026A (enExample) * | 1973-09-26 | 1975-05-20 | ||
| CA2318145C (en) * | 1998-02-04 | 2009-10-27 | Novartis Ag | Sulfonylamino derivatives which inhibit matrix-degrading metalloproteinases |
| BR9909398A (pt) * | 1998-04-03 | 2000-12-26 | Sankyo Co | Composto, medicamento, processo para impedir ou tratar a artrite, processo para inibir a metástase, a invasão ou o desenvolvimento do câncer, e, uso do composto |
| WO2006101828A1 (en) * | 2005-03-15 | 2006-09-28 | Bayer Cropscience Ag | Insecticidal alkylamino phenyl sulfonamide derivatives |
-
2007
- 2007-03-19 EP EP07104393A patent/EP1972617A1/en not_active Withdrawn
-
2008
- 2008-03-14 JP JP2010500190A patent/JP2010521529A/ja active Pending
- 2008-03-14 RU RU2009138346/04A patent/RU2488580C2/ru not_active IP Right Cessation
- 2008-03-14 CA CA002680239A patent/CA2680239A1/en not_active Abandoned
- 2008-03-14 CN CNA200880004727XA patent/CN101610997A/zh active Pending
- 2008-03-14 WO PCT/EP2008/053078 patent/WO2008113756A2/en not_active Ceased
- 2008-03-14 AU AU2008228260A patent/AU2008228260B2/en not_active Ceased
- 2008-03-14 MX MX2009009409A patent/MX2009009409A/es active IP Right Grant
- 2008-03-14 US US12/531,119 patent/US8329751B2/en not_active Expired - Fee Related
- 2008-03-14 KR KR1020097019222A patent/KR20090121329A/ko not_active Ceased
- 2008-03-14 EP EP08717820A patent/EP2121590A2/en not_active Withdrawn
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2009
- 2009-07-05 ZA ZA200905263A patent/ZA200905263B/xx unknown
- 2009-09-15 IL IL200951A patent/IL200951A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP2121590A2 (en) | 2009-11-25 |
| IL200951A0 (en) | 2010-05-17 |
| WO2008113756A8 (en) | 2008-11-06 |
| ZA200905263B (en) | 2010-06-30 |
| MX2009009409A (es) | 2009-09-14 |
| AU2008228260B2 (en) | 2012-11-22 |
| AU2008228260A1 (en) | 2008-09-25 |
| RU2488580C2 (ru) | 2013-07-27 |
| CA2680239A1 (en) | 2008-09-25 |
| US8329751B2 (en) | 2012-12-11 |
| RU2009138346A (ru) | 2011-04-27 |
| WO2008113756A2 (en) | 2008-09-25 |
| CN101610997A (zh) | 2009-12-23 |
| WO2008113756A3 (en) | 2008-12-18 |
| JP2010521529A (ja) | 2010-06-24 |
| EP1972617A1 (en) | 2008-09-24 |
| US20100087505A1 (en) | 2010-04-08 |
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