RU2420268C2 - Способ программируемой плавучей доставки - Google Patents

Способ программируемой плавучей доставки Download PDF

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Publication number
RU2420268C2
RU2420268C2 RU2009112396/15A RU2009112396A RU2420268C2 RU 2420268 C2 RU2420268 C2 RU 2420268C2 RU 2009112396/15 A RU2009112396/15 A RU 2009112396/15A RU 2009112396 A RU2009112396 A RU 2009112396A RU 2420268 C2 RU2420268 C2 RU 2420268C2
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RU
Russia
Prior art keywords
core
active agent
pharmaceutically active
agents
polymer layer
Prior art date
Application number
RU2009112396/15A
Other languages
English (en)
Russian (ru)
Other versions
RU2009112396A (ru
Inventor
Амарджит СИНГХ (IN)
Амарджит Сингх
Сарабджит СИНГХ (IN)
Сарабджит Сингх
Шивананд ПУТХЛИ (IN)
Шивананд Путхли
Раджендра ТАНДАЛЕ (IN)
Раджендра ТАНДАЛЕ
Original Assignee
Панацея Биотек Лимитед
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Панацея Биотек Лимитед filed Critical Панацея Биотек Лимитед
Publication of RU2009112396A publication Critical patent/RU2009112396A/ru
Application granted granted Critical
Publication of RU2420268C2 publication Critical patent/RU2420268C2/ru

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0065—Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Inorganic Chemistry (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Emergency Medicine (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Vascular Medicine (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
RU2009112396/15A 2006-09-04 2007-09-03 Способ программируемой плавучей доставки RU2420268C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1411/MUM/2006 2006-09-04
IN1411MU2006 2006-09-04

Publications (2)

Publication Number Publication Date
RU2009112396A RU2009112396A (ru) 2010-10-20
RU2420268C2 true RU2420268C2 (ru) 2011-06-10

Family

ID=39430167

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2009112396/15A RU2420268C2 (ru) 2006-09-04 2007-09-03 Способ программируемой плавучей доставки

Country Status (16)

Country Link
US (1) US8277843B2 (enExample)
EP (1) EP2068844A4 (enExample)
JP (1) JP2010502591A (enExample)
KR (1) KR20090065524A (enExample)
CN (1) CN101511346B (enExample)
AR (1) AR062644A1 (enExample)
AU (1) AU2007323018B2 (enExample)
BR (1) BRPI0716481A2 (enExample)
CA (1) CA2661172A1 (enExample)
CL (1) CL2007002562A1 (enExample)
IL (1) IL197121A0 (enExample)
MX (1) MX2009002371A (enExample)
NO (1) NO20090807A (enExample)
RU (1) RU2420268C2 (enExample)
WO (1) WO2008062440A2 (enExample)
ZA (1) ZA200901162B (enExample)

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WO2009153635A1 (en) * 2008-06-19 2009-12-23 University Of Witwatersrand, Johannesburg A chronotherapeutic pharmaceutical dosage form
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CA2767143A1 (en) * 2009-07-06 2011-01-13 Kyorin Pharmaceutical Co., Ltd. Tablet having hollow structure
EP3064064A1 (en) 2009-09-30 2016-09-07 Acura Pharmaceuticals, Inc. Methods and compositions for deterring abuse
US20110177231A1 (en) * 2010-01-16 2011-07-21 Alexander Grinberg Nano-, Micro-, Macro- Encapsulation And Release Of Materials
WO2011101866A2 (en) * 2010-02-17 2011-08-25 Sun Pharma Advanced Research Company Ltd., A method of treating a disease condition susceptible to baclofen therapy
EP2415460A1 (de) * 2010-08-03 2012-02-08 ratiopharm GmbH Orale Darreichungsform von Pregabalin
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WO2013009186A1 (en) * 2011-07-14 2013-01-17 APET Holding B.V. Nicotinamide compositions and the therapeutic use thereof
AU2013290875A1 (en) 2012-07-16 2015-02-05 APET Holding B.V. Gastro-retentive drug delivery system
CN104968333B (zh) 2012-11-30 2018-07-10 阿库拉制药公司 活性药物成分的自调节释放
US8859005B2 (en) 2012-12-03 2014-10-14 Intercontinental Great Brands Llc Enteric delivery of functional ingredients suitable for hot comestible applications
KR102241487B1 (ko) 2013-02-20 2021-04-16 주식회사 종근당 제어방출 펠릿으로 된 약제학적 조성물
JP2016533864A (ja) * 2013-10-22 2016-11-04 キャプソ・ヴィジョン・インコーポレーテッド マルチ密度相を有するカプセル装置に用いられるシステム及び方法
JP6510628B2 (ja) 2014-03-26 2019-05-15 サン・ファーマ・アドバンスト・リサーチ・カンパニー・リミテッド 乱用防止即時放出性被覆リザーバ固体剤形
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MX2016016406A (es) 2014-06-11 2017-10-12 Massachusetts Inst Technology Estructuras de permanencia, y métodos relacionados.
WO2017040607A1 (en) 2015-08-31 2017-03-09 Acura Pharmaceuticals, Inc. Methods and compositions for self-regulated release of active pharmaceutical ingredient
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KR102796240B1 (ko) 2015-12-08 2025-04-16 린드라 테라퓨틱스 인코퍼레이티드 위 체류 시스템을 위한 기하 구성형태
US12109305B2 (en) 2016-05-27 2024-10-08 Lyndra Therapeutics, Inc. Materials architecture for gastric residence systems
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US11534404B2 (en) * 2016-10-06 2022-12-27 Sucampo Ag Multilayer beads for pharmaceutical use
TWI811221B (zh) 2017-06-09 2023-08-11 美商萊恩卓治療公司 具有釋放速率調節膜之胃的滯留系統
WO2019025869A1 (en) * 2017-07-31 2019-02-07 Teva Pharmaceutical Industries Limited GALENIC FORMS WITH CONTROLLED RELEASE MANUFACTURED IN ADDITIVE MANNER
AU2018388577B2 (en) 2017-12-18 2024-06-06 Tris Pharma, Inc. Modified release drug powder composition comprising gastro-retentive raft forming systems having trigger pulse drug release
US12514818B2 (en) 2017-12-18 2026-01-06 Tris Pharma, Inc. Pharmaceutical compositions comprising a floating interpenetrating polymer network forming system
US11337920B2 (en) 2017-12-18 2022-05-24 Tris Pharma, Inc. Pharmaceutical composition comprising GHB gastro-retentive raft forming systems having trigger pulse drug release
US11666546B2 (en) 2017-12-18 2023-06-06 Tris Pharma, Inc GHB pharmaceutical compositions comprising a floating interpenetrating polymer network forming system
JP7000148B2 (ja) * 2017-12-27 2022-01-19 日本化薬株式会社 ダサチニブを有効成分とする医薬組成物
US20210046011A1 (en) 2019-08-12 2021-02-18 Massachusetts Institute Of Technology Articles and methods for administration of therapeutic agents
TWI763036B (zh) * 2020-09-14 2022-05-01 王子賓 可膨脹微膠囊
MX2023010744A (es) 2021-03-15 2023-11-28 Epitomee Medical Ltd Dispositivos expandibles para la administracion de agentes activos a tejidos.
KR20250112750A (ko) 2022-09-21 2025-07-24 이피토미 메디칼 엘티디 제어 가능하게 붕해될 수 있는 자체-확장가능한 섭취형 디바이스
NL2033549B1 (en) * 2022-11-17 2024-05-28 Taiwan Mercury Medical Corp Metformin tablet for relieving pain and reducing inflammation and manufacturing method thereof
CN121358468A (zh) * 2023-05-03 2026-01-16 黑暗峡谷实验室有限责任公司 用于肠道清洁产品中的固体形式的盐的漂浮药物递送系统
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WO2001058424A1 (en) * 2000-02-09 2001-08-16 West Pharmaceutical Services Drug Delivery & Clinical Research Centre Limited Floating drug delivery composition
EP1574534A1 (en) * 2004-03-11 2005-09-14 Rohm And Haas Company Polymer carriers and process

Also Published As

Publication number Publication date
AU2007323018B2 (en) 2011-02-03
RU2009112396A (ru) 2010-10-20
NO20090807A (no) 2009-06-04
US20100015224A1 (en) 2010-01-21
WO2008062440A3 (en) 2008-07-31
AR062644A1 (es) 2008-11-19
CN101511346B (zh) 2012-07-04
CL2007002562A1 (es) 2008-02-08
IL197121A0 (en) 2009-11-18
EP2068844A2 (en) 2009-06-17
CA2661172A1 (en) 2008-05-29
CN101511346A (zh) 2009-08-19
JP2010502591A (ja) 2010-01-28
EP2068844A4 (en) 2013-01-23
ZA200901162B (en) 2010-06-30
BRPI0716481A2 (pt) 2014-03-18
MX2009002371A (es) 2009-03-12
WO2008062440A2 (en) 2008-05-29
KR20090065524A (ko) 2009-06-22
US8277843B2 (en) 2012-10-02
AU2007323018A1 (en) 2008-05-29

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Effective date: 20130904