JP2010502591A - プログラム可能な浮揚性送達技術 - Google Patents

プログラム可能な浮揚性送達技術 Download PDF

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Publication number
JP2010502591A
JP2010502591A JP2009526263A JP2009526263A JP2010502591A JP 2010502591 A JP2010502591 A JP 2010502591A JP 2009526263 A JP2009526263 A JP 2009526263A JP 2009526263 A JP2009526263 A JP 2009526263A JP 2010502591 A JP2010502591 A JP 2010502591A
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Prior art keywords
active agent
core
polymer layer
polymer
layer
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Pending
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JP2009526263A
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Japanese (ja)
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JP2010502591A5 (enExample
Inventor
アマルジット シン
サラブジット シン
シヴァナンド プスリ
ラジェンドラ タンダル
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パナセア バイオテック リミテッド
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Publication of JP2010502591A publication Critical patent/JP2010502591A/ja
Publication of JP2010502591A5 publication Critical patent/JP2010502591A5/ja
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0065Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2095Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Inorganic Chemistry (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2009526263A 2006-09-04 2007-09-03 プログラム可能な浮揚性送達技術 Pending JP2010502591A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1411MU2006 2006-09-04
PCT/IN2007/000392 WO2008062440A2 (en) 2006-09-04 2007-09-03 Programmable buoyant delivery technology

Publications (2)

Publication Number Publication Date
JP2010502591A true JP2010502591A (ja) 2010-01-28
JP2010502591A5 JP2010502591A5 (enExample) 2010-10-14

Family

ID=39430167

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009526263A Pending JP2010502591A (ja) 2006-09-04 2007-09-03 プログラム可能な浮揚性送達技術

Country Status (16)

Country Link
US (1) US8277843B2 (enExample)
EP (1) EP2068844A4 (enExample)
JP (1) JP2010502591A (enExample)
KR (1) KR20090065524A (enExample)
CN (1) CN101511346B (enExample)
AR (1) AR062644A1 (enExample)
AU (1) AU2007323018B2 (enExample)
BR (1) BRPI0716481A2 (enExample)
CA (1) CA2661172A1 (enExample)
CL (1) CL2007002562A1 (enExample)
IL (1) IL197121A0 (enExample)
MX (1) MX2009002371A (enExample)
NO (1) NO20090807A (enExample)
RU (1) RU2420268C2 (enExample)
WO (1) WO2008062440A2 (enExample)
ZA (1) ZA200901162B (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013535477A (ja) * 2010-08-03 2013-09-12 ラシオファルム ゲーエムベーハー プレガバリンの経口投与剤形
JP2019116435A (ja) * 2017-12-27 2019-07-18 日本化薬株式会社 ダサチニブを有効成分とする医薬組成物
JP2019529467A (ja) * 2016-10-06 2019-10-17 スキャンポ・アーゲーSucampo AG 医薬品用途のための多層ビーズ

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US7201920B2 (en) 2003-11-26 2007-04-10 Acura Pharmaceuticals, Inc. Methods and compositions for deterring abuse of opioid containing dosage forms
WO2009153635A1 (en) * 2008-06-19 2009-12-23 University Of Witwatersrand, Johannesburg A chronotherapeutic pharmaceutical dosage form
ZA200903858B (en) * 2008-06-19 2013-10-30 Univ Of Witwatesrand Johannesburg Pharmaceutical dosage form
CA2638240C (en) * 2008-08-29 2010-02-02 Alexander Macgregor Method of treating dysglycemia and glucose excursions
CA2767143A1 (en) * 2009-07-06 2011-01-13 Kyorin Pharmaceutical Co., Ltd. Tablet having hollow structure
US8901113B2 (en) 2009-09-30 2014-12-02 Acura Pharmaceuticals, Inc. Methods and compositions for deterring abuse
US20110177231A1 (en) * 2010-01-16 2011-07-21 Alexander Grinberg Nano-, Micro-, Macro- Encapsulation And Release Of Materials
US20110200671A1 (en) * 2010-02-17 2011-08-18 Sun Pharma Advanced Research Company Ltd. Method of treating a disease condition susceptible to baclofen therapy
GB201102148D0 (en) 2011-02-08 2011-03-23 Ucl Business Plc Layered bodies, compositions containing them and processes for producing them
BR112014000773A8 (pt) * 2011-07-14 2017-10-03 Apet Holding B V Composições de nicotinamida e uso terapêutico das mesmas
ES2691982T3 (es) 2012-11-30 2018-11-29 Acura Pharmaceuticals, Inc. Liberación autorregulada de un principio activo farmacéutico
US8859005B2 (en) 2012-12-03 2014-10-14 Intercontinental Great Brands Llc Enteric delivery of functional ingredients suitable for hot comestible applications
KR102241487B1 (ko) 2013-02-20 2021-04-16 주식회사 종근당 제어방출 펠릿으로 된 약제학적 조성물
US20160242632A1 (en) * 2013-10-22 2016-08-25 Ganyu Lu System and Method for Capsule Device with Multiple Phases of Density
WO2015145461A1 (en) 2014-03-26 2015-10-01 Sun Pharma Advanced Research Company Ltd. Abuse deterrent immediate release biphasic matrix solid dosage form
CN106714893B (zh) 2014-06-11 2021-01-01 麻省理工学院 自组装的驻留装置及相关方法
US20170266112A1 (en) 2014-06-11 2017-09-21 Massachusetts Institute Of Technology Residence structures and related methods
WO2017040607A1 (en) 2015-08-31 2017-03-09 Acura Pharmaceuticals, Inc. Methods and compositions for self-regulated release of active pharmaceutical ingredient
HK1258050A1 (zh) 2015-10-23 2019-11-01 Lyndra Therapeutics, Inc. 用於治疗剂缓释的胃驻留系统及其使用方法
WO2017100367A1 (en) 2015-12-08 2017-06-15 Lyndra, Inc. Geometric configurations for gastric residence systems
AU2017268840B2 (en) 2016-05-27 2022-02-10 Lyndra Therapeutics, Inc. Materials architecture for gastric residence systems
WO2018064630A1 (en) 2016-09-30 2018-04-05 Lyndra, Inc. Gastric residence systems for sustained delivery of adamantane-class drugs
CA3066658A1 (en) 2017-06-09 2018-12-13 Lyndra, Inc. Gastric residence systems with release rate-modulating films
WO2019025869A1 (en) * 2017-07-31 2019-02-07 Teva Pharmaceutical Industries Limited GALENIC FORMS WITH CONTROLLED RELEASE MANUFACTURED IN ADDITIVE MANNER
CA3086153A1 (en) 2017-12-18 2019-06-27 Tris Pharma, Inc. Modified release drug powder composition comprising gastro-retentive raft forming systems having trigger pulse drug release
US11337920B2 (en) 2017-12-18 2022-05-24 Tris Pharma, Inc. Pharmaceutical composition comprising GHB gastro-retentive raft forming systems having trigger pulse drug release
CA3085941A1 (en) 2017-12-18 2019-06-27 Tris Pharma, Inc. Ghb pharmaceutical compositions comprising a floating interpenetrating polymer network forming system
EP4013401A4 (en) 2019-08-12 2023-07-12 Massachusetts Institute of Technology Articles and methods for administration of therapeutic agents
TWI763036B (zh) * 2020-09-14 2022-05-01 王子賓 可膨脹微膠囊
BR112023018524A2 (pt) 2021-03-15 2023-11-21 Epitomee Medical Ltd Dispositivos expansíveis para entrega de agentes ativos aos tecidos
KR20250112750A (ko) 2022-09-21 2025-07-24 이피토미 메디칼 엘티디 제어 가능하게 붕해될 수 있는 자체-확장가능한 섭취형 디바이스
NL2033549B1 (en) * 2022-11-17 2024-05-28 Taiwan Mercury Medical Corp Metformin tablet for relieving pain and reducing inflammation and manufacturing method thereof
AU2024265092A1 (en) * 2023-05-03 2025-11-20 Dark Canyon Laboratories, Llc A floating drug delivery system for solid forms of salts used in bowel cleansing products

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JPH03101615A (ja) * 1989-09-14 1991-04-26 Sumitomo Pharmaceut Co Ltd 胃内滞留型持続性製剤
JPH05506217A (ja) * 1990-04-17 1993-09-16 ユーランド・インターナショナル・ソシエタ・ペル・アチオニ 制御放出薬剤処方
JP2002370970A (ja) * 2001-06-12 2002-12-24 Sanwa Kagaku Kenkyusho Co Ltd 胃内浮遊型固形製剤及びその製造方法

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SE9702533D0 (sv) * 1997-07-01 1997-07-01 Astra Ab New oral formulation
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JP4426286B2 (ja) * 2001-07-10 2010-03-03 テバ ファーマシューティカル インダストリーズ リミティド 0次、0次−二相性、上昇型又は下降型薬物放出のための薬物送達システム
US7763663B2 (en) * 2001-12-19 2010-07-27 University Of Massachusetts Polysaccharide-containing block copolymer particles and uses thereof
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Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03101615A (ja) * 1989-09-14 1991-04-26 Sumitomo Pharmaceut Co Ltd 胃内滞留型持続性製剤
JPH05506217A (ja) * 1990-04-17 1993-09-16 ユーランド・インターナショナル・ソシエタ・ペル・アチオニ 制御放出薬剤処方
JP2002370970A (ja) * 2001-06-12 2002-12-24 Sanwa Kagaku Kenkyusho Co Ltd 胃内浮遊型固形製剤及びその製造方法

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013535477A (ja) * 2010-08-03 2013-09-12 ラシオファルム ゲーエムベーハー プレガバリンの経口投与剤形
JP2019529467A (ja) * 2016-10-06 2019-10-17 スキャンポ・アーゲーSucampo AG 医薬品用途のための多層ビーズ
JP2019116435A (ja) * 2017-12-27 2019-07-18 日本化薬株式会社 ダサチニブを有効成分とする医薬組成物
JP7000148B2 (ja) 2017-12-27 2022-01-19 日本化薬株式会社 ダサチニブを有効成分とする医薬組成物

Also Published As

Publication number Publication date
BRPI0716481A2 (pt) 2014-03-18
WO2008062440A3 (en) 2008-07-31
RU2009112396A (ru) 2010-10-20
CL2007002562A1 (es) 2008-02-08
KR20090065524A (ko) 2009-06-22
NO20090807A (no) 2009-06-04
CN101511346A (zh) 2009-08-19
MX2009002371A (es) 2009-03-12
AU2007323018B2 (en) 2011-02-03
CA2661172A1 (en) 2008-05-29
AU2007323018A1 (en) 2008-05-29
CN101511346B (zh) 2012-07-04
EP2068844A4 (en) 2013-01-23
WO2008062440A2 (en) 2008-05-29
IL197121A0 (en) 2009-11-18
AR062644A1 (es) 2008-11-19
EP2068844A2 (en) 2009-06-17
US20100015224A1 (en) 2010-01-21
US8277843B2 (en) 2012-10-02
RU2420268C2 (ru) 2011-06-10
ZA200901162B (en) 2010-06-30

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