RU2415432C2 - Точный магнитный биодатчик - Google Patents

Точный магнитный биодатчик Download PDF

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Publication number
RU2415432C2
RU2415432C2 RU2008101786/14A RU2008101786A RU2415432C2 RU 2415432 C2 RU2415432 C2 RU 2415432C2 RU 2008101786/14 A RU2008101786/14 A RU 2008101786/14A RU 2008101786 A RU2008101786 A RU 2008101786A RU 2415432 C2 RU2415432 C2 RU 2415432C2
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RU
Russia
Prior art keywords
magnetic
measuring device
marks
concentration
binding
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RU2008101786/14A
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English (en)
Russian (ru)
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RU2008101786A (ru
Inventor
Менно В.Й. ПРИНС (NL)
Менно В.Й. ПРИНС
Альберт Х.Й. ИММИНК (NL)
Альберт Х.Й. ИММИНК
Original Assignee
Конинклейке Филипс Электроникс Н.В.
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G01N33/54333—Modification of conditions of immunological binding reaction, e.g. use of more than one type of particle, use of chemical agents to improve binding, choice of incubation time or application of magnetic field during binding reaction
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/72—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables
    • G01N27/74—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids
    • G01N27/745—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids for detecting magnetic beads used in biochemical assays
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing

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  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Electrochemistry (AREA)
  • Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
RU2008101786/14A 2005-06-17 2006-06-12 Точный магнитный биодатчик RU2415432C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05105361 2005-06-17
EP05105361.9 2005-06-17

Publications (2)

Publication Number Publication Date
RU2008101786A RU2008101786A (ru) 2009-07-27
RU2415432C2 true RU2415432C2 (ru) 2011-03-27

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Family Applications (1)

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RU2008101786/14A RU2415432C2 (ru) 2005-06-17 2006-06-12 Точный магнитный биодатчик

Country Status (7)

Country Link
US (1) US20080206104A1 (https=)
EP (1) EP1894009A2 (https=)
JP (1) JP2008544246A (https=)
CN (1) CN101198870A (https=)
BR (1) BRPI0612623A2 (https=)
RU (1) RU2415432C2 (https=)
WO (1) WO2006134546A2 (https=)

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CN101438142B (zh) 2006-05-10 2013-10-30 皇家飞利浦电子股份有限公司 快速磁生物传感器
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CN101490528A (zh) * 2006-07-17 2009-07-22 皇家飞利浦电子股份有限公司 将可磁化对象磁吸引到传感器表面和磁排斥离开传感器表面
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WO2008102218A1 (en) * 2007-02-23 2008-08-28 Koninklijke Philips Electronics N.V. A sensor device for and a method of sensing magnetic particles
WO2008102299A1 (en) * 2007-02-23 2008-08-28 Koninklijke Philips Electronics N.V. Magnetic sensor device with field generator and sensor element
DE102007015543A1 (de) * 2007-03-30 2008-10-09 Siemens Ag Verfahren und Anordnung zur Detektion biologischer Reaktionsprodukte
EP2017619A1 (en) * 2007-07-20 2009-01-21 Koninklijke Philips Electronics N.V. Magnetic sensor device
EP2017618A1 (en) * 2007-07-20 2009-01-21 Koninklijke Philips Electronics N.V. Methods and systems for detecting
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EP2028491A1 (en) * 2007-08-22 2009-02-25 Koninklijke Philips Electronics N.V. Method of directing magnetic or magnetisable objects to prepare bio-sensor device
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CN101932937A (zh) * 2007-12-04 2010-12-29 皇家飞利浦电子股份有限公司 使用标记粒子测量流体中分子的方法
EP2073016A1 (en) * 2007-12-20 2009-06-24 Koninklijke Philips Electronics N.V. Magnetic label based detection
CA2711956A1 (en) 2008-01-17 2009-07-23 The Regents Of The University Of California Integrated magnetic field generation and detection platform
JP5628784B2 (ja) * 2008-03-17 2014-11-19 コーニンクレッカ フィリップス エヌ ヴェ 磁性粒子によるアッセイ用カートリッジ
US8053250B2 (en) * 2008-06-27 2011-11-08 Rex Chin-Yih Hong Method and system for suppressing bindings on magnetic particles
EP2340434B1 (en) 2008-10-17 2014-03-19 Koninklijke Philips N.V. Pulsed magnetic actuation for sensitive assays
EP2208531A1 (en) 2008-12-30 2010-07-21 Atonomics A/S Distribution of particles in capillary channel by application of magnetic field
US8993236B2 (en) * 2009-04-17 2015-03-31 California Institute Of Technology Electromagnetic molecular sensors and methods of using same
US9599591B2 (en) 2009-03-06 2017-03-21 California Institute Of Technology Low cost, portable sensor for molecular assays
US20120208296A1 (en) 2009-08-19 2012-08-16 Koninklijke Philips Electronics N.V. Detection of different target components by cluster formation
US9772272B2 (en) 2009-09-28 2017-09-26 Koninklijke Philips N.V. Substance determining apparatus
RU2595843C2 (ru) 2009-10-16 2016-08-27 Омик Аб Способ анализа и устройства с применением магнитных частиц
JPWO2011049044A1 (ja) * 2009-10-19 2013-03-14 国立大学法人東京工業大学 磁性微粒子を用いるバイオセンサ
CN102656443B (zh) 2009-12-18 2016-01-20 皇家飞利浦电子股份有限公司 物质确定设备
EP2362219A1 (en) * 2010-02-19 2011-08-31 Nxp B.V. Sensor measuring method and sensing apparatus
US9778225B2 (en) 2010-11-15 2017-10-03 Regents Of The University Of Minnesota Magnetic search coil for measuring real-time brownian relaxation of magnetic nanoparticles
US9304130B2 (en) * 2010-12-16 2016-04-05 International Business Machines Corporation Trenched sample assembly for detection of analytes with electromagnetic read-write heads
US9040311B2 (en) 2011-05-03 2015-05-26 International Business Machines Corporation Calibration assembly for aide in detection of analytes with electromagnetic read-write heads
US8855957B2 (en) 2011-05-03 2014-10-07 International Business Machines Corporation Method for calibrating read sensors of electromagnetic read-write heads
US9977015B2 (en) * 2012-05-15 2018-05-22 Massachusetts Institute Of Technology Systems and methods for detecting molecular interactions using magnetic beads
BR112015004406A2 (pt) * 2012-09-04 2017-07-04 Koninklijke Philips Nv método de amostragem e dispositivo sensor
US9435800B2 (en) 2012-09-14 2016-09-06 International Business Machines Corporation Sample assembly with an electromagnetic field to accelerate the bonding of target antigens and nanoparticles
KR101517594B1 (ko) 2013-10-16 2015-05-04 (주)타스컴 바이오 센서
WO2015173729A1 (en) * 2014-05-12 2015-11-19 Qi, Huan Method and system for analyte sensing
JP6594995B2 (ja) * 2015-03-26 2019-10-23 コーニンクレッカ フィリップス エヌ ヴェ バイオセンサカートリッジの製造
EP3290938A1 (en) 2016-09-05 2018-03-07 Industrial Technology Research Institute Biomolecule magnetic sensor
US20180266991A1 (en) * 2017-03-15 2018-09-20 Qualcomm Incorporated Magneto-impedance (mi) sensors employing current confinement and exchange bias layer(s) for increased sensitivity
GB201720162D0 (en) * 2017-12-04 2018-01-17 Univ Oxford Innovation Ltd Method
AU2019310601A1 (en) 2018-07-27 2021-02-04 Zepto Life Technology, Inc. System and method for sensing analytes in GMR-based detection of biomarkers
EP4087625A4 (en) 2020-01-08 2024-03-13 Zepto Life Technology, LLC POLYMER COMPOSITIONS AND BIOSURFACES INCLUDING THEM ON SENSORS
EP4592678A1 (en) 2024-01-26 2025-07-30 Technische Universität München Method and device for detecting a concentration of at least one analyte in a sample

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Publication number Priority date Publication date Assignee Title
WO2013078332A1 (en) * 2011-11-23 2013-05-30 The General Hospital Corporation Analyte detection using magnetic hall effect
US9958416B2 (en) 2011-11-23 2018-05-01 The General Hospital Corporation Analyte detection using magnetic hall effect

Also Published As

Publication number Publication date
RU2008101786A (ru) 2009-07-27
JP2008544246A (ja) 2008-12-04
US20080206104A1 (en) 2008-08-28
WO2006134546A3 (en) 2007-03-08
EP1894009A2 (en) 2008-03-05
CN101198870A (zh) 2008-06-11
BRPI0612623A2 (pt) 2016-11-29
WO2006134546A2 (en) 2006-12-21

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Effective date: 20110613