RU2391344C2 - ПРОИЗВОДНЫЕ 7Н-ПИРРОЛ[2,3-d]ПИРИМИДИНА, ИХ ФАРМАЦЕВТИЧЕСКИ ПРИЕМЛЕМЫЕ СОЛИ, СОДЕРЖАЩИЕ ИХ ФАРМАЦЕВТИЧЕСКИЕ КОМПОЗИЦИИ И СПОСОБ ИХ ПОЛУЧЕНИЯ - Google Patents

ПРОИЗВОДНЫЕ 7Н-ПИРРОЛ[2,3-d]ПИРИМИДИНА, ИХ ФАРМАЦЕВТИЧЕСКИ ПРИЕМЛЕМЫЕ СОЛИ, СОДЕРЖАЩИЕ ИХ ФАРМАЦЕВТИЧЕСКИЕ КОМПОЗИЦИИ И СПОСОБ ИХ ПОЛУЧЕНИЯ Download PDF

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RU2391344C2
RU2391344C2 RU2006141393/04A RU2006141393A RU2391344C2 RU 2391344 C2 RU2391344 C2 RU 2391344C2 RU 2006141393/04 A RU2006141393/04 A RU 2006141393/04A RU 2006141393 A RU2006141393 A RU 2006141393A RU 2391344 C2 RU2391344 C2 RU 2391344C2
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Russia
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carbon atoms
alkyl
formula
phenyl
optionally substituted
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RU2006141393/04A
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Russian (ru)
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RU2006141393A (ru
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Янош СЁЛЧАНЬИ (HU)
Янош СЁЛЧАНЬИ
Дьёрдь КЕРИ (HU)
Дьёрдь КЕРИ
Ласло ЭРФИ (HU)
Ласло ЭРФИ
Фридьёш ВАЦЕК (HU)
Фридьёш ВАЦЕК
Эрика ПИНТЕР (HU)
Эрика ПИНТЕР
Жужанна ХЕЛЙЕС (HU)
Жужанна ХЕЛЙЕС
Тамаш СЮТШ (HU)
Тамаш СЮТШ
Йожеф НЕМЕТ (HU)
Йожеф НЕМЕТ
Original Assignee
Янош СЁЛЧАНЬИ
Ласло ЭРФИ
Дьёрдь КЕРИ
Фридьёш ВАЦЕК
Эрика ПИНТЕР
Жужанна ХЕЛЙЕС
Тамаш СЮТШ
Йожеф НЕМЕТ
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
RU2006141393/04A 2004-04-29 2005-04-25 ПРОИЗВОДНЫЕ 7Н-ПИРРОЛ[2,3-d]ПИРИМИДИНА, ИХ ФАРМАЦЕВТИЧЕСКИ ПРИЕМЛЕМЫЕ СОЛИ, СОДЕРЖАЩИЕ ИХ ФАРМАЦЕВТИЧЕСКИЕ КОМПОЗИЦИИ И СПОСОБ ИХ ПОЛУЧЕНИЯ RU2391344C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HUP0400891 2004-04-29
HU0400891A HUP0400891A2 (en) 2004-04-29 2004-04-29 7h-pyrrolo[2,3-d]pyrimidine derivatives, their pharmaceutically acceptable salts, pharmaceutical compositions containing them and process for the production of the compounds

Publications (2)

Publication Number Publication Date
RU2006141393A RU2006141393A (ru) 2008-06-10
RU2391344C2 true RU2391344C2 (ru) 2010-06-10

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
RU2006141393/04A RU2391344C2 (ru) 2004-04-29 2005-04-25 ПРОИЗВОДНЫЕ 7Н-ПИРРОЛ[2,3-d]ПИРИМИДИНА, ИХ ФАРМАЦЕВТИЧЕСКИ ПРИЕМЛЕМЫЕ СОЛИ, СОДЕРЖАЩИЕ ИХ ФАРМАЦЕВТИЧЕСКИЕ КОМПОЗИЦИИ И СПОСОБ ИХ ПОЛУЧЕНИЯ

Country Status (13)

Country Link
US (1) US20080214583A1 (enExample)
EP (1) EP1756110B1 (enExample)
JP (1) JP2007534737A (enExample)
KR (1) KR20070047737A (enExample)
CN (1) CN1972946A (enExample)
AT (1) ATE462706T1 (enExample)
AU (1) AU2005238287A1 (enExample)
CA (1) CA2564277A1 (enExample)
DE (1) DE602005020281D1 (enExample)
HU (1) HUP0400891A2 (enExample)
IL (1) IL178906A0 (enExample)
RU (1) RU2391344C2 (enExample)
WO (1) WO2005105804A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2603770C2 (ru) * 2014-11-28 2016-11-27 Федеральное государственное автономное образовательное учреждение высшего образования "Белгородский государственный национальный исследовательский университет" (НИУ "БелГУ") Замещенные пиразинопиримидиноны как блокаторы trpa1 каналов, фармацевтическая композиция, способы их получения и применения

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2873971A1 (en) * 2012-05-21 2013-11-28 Bayer Pharma Aktiengesellschaft Substituted pyrrolopyrimidines
WO2014145576A2 (en) * 2013-03-15 2014-09-18 Northwestern University Substituted pyrrolo(2,3-d)pyrimidines for the treatment of cancer
EP3194399B1 (en) 2014-09-17 2019-04-10 Pécsi Tudományegyetem New agents for treating neurogenic inflammation and neuropathic hyperalgesia related disorders
CN110483526B (zh) * 2019-09-09 2021-10-01 辽宁大学 含芳基腙结构的吡唑并[1,5-a]嘧啶类衍生物及其应用
CN119613409A (zh) * 2024-12-05 2025-03-14 浙江工业大学 吡咯并[2,3-d]嘧啶衍生物及其在制备抗炎药物中的应用

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4229453A (en) * 1978-04-27 1980-10-21 Bayer Aktiengesellschaft Substituted 5,6-dimethylpyrrolo[2,3-d]pyrimidine compounds, their production and their medicinal use
EP1081149A1 (en) * 1998-05-19 2001-03-07 Otsuka Pharmaceutical Factory, Inc. PYRAZOLO 1,5-a]PYRIMIDINE DERIVATIVES
WO2001042246A2 (en) * 1999-12-10 2001-06-14 Pfizer Products Inc. PYRROLO[2,3-d]PYRIMIDINE COMPOUNDS
RU2001111033A (ru) * 1998-09-18 2003-05-20 Басф Акциенгезелльшафт (De) Пирролопиримидины в качестве ингибиторов протеинкиназ

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2007001399A (es) * 2004-08-02 2007-04-18 Osi Pharm Inc Compuestos que inhiben pirrolopirimidina multi-cinasa aril-amino sustituidas.

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4229453A (en) * 1978-04-27 1980-10-21 Bayer Aktiengesellschaft Substituted 5,6-dimethylpyrrolo[2,3-d]pyrimidine compounds, their production and their medicinal use
EP1081149A1 (en) * 1998-05-19 2001-03-07 Otsuka Pharmaceutical Factory, Inc. PYRAZOLO 1,5-a]PYRIMIDINE DERIVATIVES
RU2001111033A (ru) * 1998-09-18 2003-05-20 Басф Акциенгезелльшафт (De) Пирролопиримидины в качестве ингибиторов протеинкиназ
WO2001042246A2 (en) * 1999-12-10 2001-06-14 Pfizer Products Inc. PYRROLO[2,3-d]PYRIMIDINE COMPOUNDS

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
BASYOUNI W.M.; HOSNI H.M.; EL-BAYOUKI K.A. M., JOURNAL OF CHEMICAL RESEARCH. MINIPRINT, 1997, Vol:12, Page(s):2771-2789. TRAXLER P.M. ET AL. JOURNAL OF MEDICINAL CHEMISTRY, 1996, Vol:39, Nr:12, Page(s):2285-2292. *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2603770C2 (ru) * 2014-11-28 2016-11-27 Федеральное государственное автономное образовательное учреждение высшего образования "Белгородский государственный национальный исследовательский университет" (НИУ "БелГУ") Замещенные пиразинопиримидиноны как блокаторы trpa1 каналов, фармацевтическая композиция, способы их получения и применения

Also Published As

Publication number Publication date
RU2006141393A (ru) 2008-06-10
CN1972946A (zh) 2007-05-30
WO2005105804A1 (en) 2005-11-10
CA2564277A1 (en) 2005-11-10
EP1756110B1 (en) 2010-03-31
DE602005020281D1 (de) 2010-05-12
EP1756110A1 (en) 2007-02-28
JP2007534737A (ja) 2007-11-29
US20080214583A1 (en) 2008-09-04
HUP0400891A2 (en) 2006-04-28
HU0400891D0 (en) 2004-07-28
IL178906A0 (en) 2007-03-08
AU2005238287A1 (en) 2005-11-10
ATE462706T1 (de) 2010-04-15
KR20070047737A (ko) 2007-05-07

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Effective date: 20110426