ATE462706T1 - 7h-pyrroloä2,3-düpyrimidinderivate sowie deren therapeutisch annehmbare salze, pharmazeutische zubereitungen, die diese enthalten, und verfahren zur herstellung des wirkstoffs - Google Patents
7h-pyrroloä2,3-düpyrimidinderivate sowie deren therapeutisch annehmbare salze, pharmazeutische zubereitungen, die diese enthalten, und verfahren zur herstellung des wirkstoffsInfo
- Publication number
- ATE462706T1 ATE462706T1 AT05739554T AT05739554T ATE462706T1 AT E462706 T1 ATE462706 T1 AT E462706T1 AT 05739554 T AT05739554 T AT 05739554T AT 05739554 T AT05739554 T AT 05739554T AT E462706 T1 ATE462706 T1 AT E462706T1
- Authority
- AT
- Austria
- Prior art keywords
- producing
- acceptable salts
- pharmaceutical preparations
- preparations containing
- derivatives
- Prior art date
Links
- 239000000825 pharmaceutical preparation Substances 0.000 title abstract 3
- 239000013543 active substance Substances 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
- 238000002360 preparation method Methods 0.000 abstract 2
- JJTNLWSCFYERCK-UHFFFAOYSA-N 7h-pyrrolo[2,3-d]pyrimidine Chemical class N1=CN=C2NC=CC2=C1 JJTNLWSCFYERCK-UHFFFAOYSA-N 0.000 abstract 1
- 241000206576 Chondrus Species 0.000 abstract 1
- 201000004624 Dermatitis Diseases 0.000 abstract 1
- 208000004454 Hyperalgesia Diseases 0.000 abstract 1
- 208000035154 Hyperesthesia Diseases 0.000 abstract 1
- 201000004681 Psoriasis Diseases 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 239000002260 anti-inflammatory agent Substances 0.000 abstract 1
- 230000001741 anti-phlogistic effect Effects 0.000 abstract 1
- 208000006673 asthma Diseases 0.000 abstract 1
- 208000010668 atopic eczema Diseases 0.000 abstract 1
- 210000000988 bone and bone Anatomy 0.000 abstract 1
- 230000006378 damage Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000002981 neuropathic effect Effects 0.000 abstract 1
- 201000003068 rheumatic fever Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pain & Pain Management (AREA)
- Dermatology (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU0400891A HUP0400891A2 (en) | 2004-04-29 | 2004-04-29 | 7h-pyrrolo[2,3-d]pyrimidine derivatives, their pharmaceutically acceptable salts, pharmaceutical compositions containing them and process for the production of the compounds |
| PCT/HU2005/000040 WO2005105804A1 (en) | 2004-04-29 | 2005-04-25 | 7H-PYRROLO[2,3-d]PYRIMIDINE DERIVATIVES, AS WELL AS THEIR THERAPEUTICALLY ACCEPTABLE SALTS, PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND PROCESS FOR PRODUCTION THE ACTIVE AGENT |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE462706T1 true ATE462706T1 (de) | 2010-04-15 |
Family
ID=89982174
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05739554T ATE462706T1 (de) | 2004-04-29 | 2005-04-25 | 7h-pyrroloä2,3-düpyrimidinderivate sowie deren therapeutisch annehmbare salze, pharmazeutische zubereitungen, die diese enthalten, und verfahren zur herstellung des wirkstoffs |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20080214583A1 (de) |
| EP (1) | EP1756110B1 (de) |
| JP (1) | JP2007534737A (de) |
| KR (1) | KR20070047737A (de) |
| CN (1) | CN1972946A (de) |
| AT (1) | ATE462706T1 (de) |
| AU (1) | AU2005238287A1 (de) |
| CA (1) | CA2564277A1 (de) |
| DE (1) | DE602005020281D1 (de) |
| HU (1) | HUP0400891A2 (de) |
| IL (1) | IL178906A0 (de) |
| RU (1) | RU2391344C2 (de) |
| WO (1) | WO2005105804A1 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2852593A1 (de) * | 2012-05-21 | 2015-04-01 | Bayer Pharma Aktiengesellschaft | Substituierte pyrrolopyrimidine |
| WO2014145576A2 (en) | 2013-03-15 | 2014-09-18 | Northwestern University | Substituted pyrrolo(2,3-d)pyrimidines for the treatment of cancer |
| US10344032B2 (en) | 2014-09-17 | 2019-07-09 | Pécsi Tudományegyetem | Agents for treating neurogenic inflammation and neuropathic hyperalgesia related disorders |
| RU2603770C2 (ru) * | 2014-11-28 | 2016-11-27 | Федеральное государственное автономное образовательное учреждение высшего образования "Белгородский государственный национальный исследовательский университет" (НИУ "БелГУ") | Замещенные пиразинопиримидиноны как блокаторы trpa1 каналов, фармацевтическая композиция, способы их получения и применения |
| CN110483526B (zh) * | 2019-09-09 | 2021-10-01 | 辽宁大学 | 含芳基腙结构的吡唑并[1,5-a]嘧啶类衍生物及其应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2818676A1 (de) * | 1978-04-27 | 1979-11-08 | Troponwerke Gmbh & Co Kg | Substituierte 5,6-dimethylpyrrolo 2,3-d pyrimidine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| EP1081149B1 (de) * | 1998-05-19 | 2003-04-02 | Otsuka Pharmaceutical Factory, Inc. | PYRAZOLO[1,5-a]PYRIMIDINE |
| KR100477818B1 (ko) * | 1999-12-10 | 2005-03-22 | 화이자 프로덕츠 인코포레이티드 | 피롤로[2,3-ｄ] 피리미딘 화합물 |
| US7465726B2 (en) * | 2004-08-02 | 2008-12-16 | Osi Pharmaceuticals, Inc. | Substituted pyrrolo[2.3-B]pyridines |
-
2004
- 2004-04-29 HU HU0400891A patent/HUP0400891A2/hu unknown
-
2005
- 2005-04-25 WO PCT/HU2005/000040 patent/WO2005105804A1/en active Application Filing
- 2005-04-25 JP JP2007510131A patent/JP2007534737A/ja not_active Withdrawn
- 2005-04-25 EP EP05739554A patent/EP1756110B1/de active Active
- 2005-04-25 CA CA002564277A patent/CA2564277A1/en not_active Abandoned
- 2005-04-25 DE DE602005020281T patent/DE602005020281D1/de not_active Expired - Fee Related
- 2005-04-25 AT AT05739554T patent/ATE462706T1/de not_active IP Right Cessation
- 2005-04-25 KR KR1020067025009A patent/KR20070047737A/ko not_active Application Discontinuation
- 2005-04-25 US US11/587,851 patent/US20080214583A1/en not_active Abandoned
- 2005-04-25 RU RU2006141393/04A patent/RU2391344C2/ru not_active IP Right Cessation
- 2005-04-25 CN CNA2005800206893A patent/CN1972946A/zh active Pending
- 2005-04-25 AU AU2005238287A patent/AU2005238287A1/en not_active Abandoned
-
2006
- 2006-10-26 IL IL178906A patent/IL178906A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR20070047737A (ko) | 2007-05-07 |
| DE602005020281D1 (de) | 2010-05-12 |
| US20080214583A1 (en) | 2008-09-04 |
| EP1756110B1 (de) | 2010-03-31 |
| EP1756110A1 (de) | 2007-02-28 |
| HU0400891D0 (en) | 2004-07-28 |
| CN1972946A (zh) | 2007-05-30 |
| CA2564277A1 (en) | 2005-11-10 |
| IL178906A0 (en) | 2007-03-08 |
| WO2005105804A1 (en) | 2005-11-10 |
| JP2007534737A (ja) | 2007-11-29 |
| AU2005238287A1 (en) | 2005-11-10 |
| HUP0400891A2 (en) | 2006-04-28 |
| RU2006141393A (ru) | 2008-06-10 |
| RU2391344C2 (ru) | 2010-06-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |