RU2375047C2 - Фармацевтическая лекарственная форма, устойчивая к действию желудочного сока, включающая n-(2-(2-фталимидоэтокси)ацетил)-l-аланил-d-глутаминовую кислоту (lk 423) - Google Patents

Фармацевтическая лекарственная форма, устойчивая к действию желудочного сока, включающая n-(2-(2-фталимидоэтокси)ацетил)-l-аланил-d-глутаминовую кислоту (lk 423) Download PDF

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Publication number
RU2375047C2
RU2375047C2 RU2006137660/15A RU2006137660A RU2375047C2 RU 2375047 C2 RU2375047 C2 RU 2375047C2 RU 2006137660/15 A RU2006137660/15 A RU 2006137660/15A RU 2006137660 A RU2006137660 A RU 2006137660A RU 2375047 C2 RU2375047 C2 RU 2375047C2
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RU
Russia
Prior art keywords
coated
dosage form
pharmaceutical dosage
coating
group
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RU2006137660/15A
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English (en)
Russian (ru)
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RU2006137660A (ru
Inventor
Мария БОГАТАЙ (SI)
Мария БОГАТАЙ
Алес МРХАР (SI)
Алес МРХАР
Антон ЛАВРИЦ (SI)
Антон ЛАВРИЦ
Маница ЦЕРНЕ (SI)
Маница ЦЕРНЕ
Дорис ТИБАУТ (SI)
Дорис ТИБАУТ
Антон СТАЛЦ (SI)
Антон СТАЛЦ
Урос УРЛЕБ (SI)
Урос УРЛЕБ
Татьяна МАТЕОВИЦ (SI)
Татьяна МАТЕОВИЦ
Грета ЦОФ (SI)
Грета ЦОФ
Янез КЕРК (SI)
Янез КЕРК
Рок ДРЕУ (SI)
Рок Дреу
Фумио ЙОНЕДА (JP)
Фумио ЙОНЕДА
Шизуко МУРАОКА (JP)
Шизуко МУРАОКА
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Лек Фармасьютиклз Д.Д.
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Publication of RU2006137660A publication Critical patent/RU2006137660A/ru
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
RU2006137660/15A 2004-03-26 2005-03-24 Фармацевтическая лекарственная форма, устойчивая к действию желудочного сока, включающая n-(2-(2-фталимидоэтокси)ацетил)-l-аланил-d-глутаминовую кислоту (lk 423) RU2375047C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SIP200400094 2004-03-26
SI200400094 2004-03-26

Publications (2)

Publication Number Publication Date
RU2006137660A RU2006137660A (ru) 2008-05-10
RU2375047C2 true RU2375047C2 (ru) 2009-12-10

Family

ID=34964906

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2006137660/15A RU2375047C2 (ru) 2004-03-26 2005-03-24 Фармацевтическая лекарственная форма, устойчивая к действию желудочного сока, включающая n-(2-(2-фталимидоэтокси)ацетил)-l-аланил-d-глутаминовую кислоту (lk 423)

Country Status (15)

Country Link
US (1) US20100183714A1 (https=)
EP (1) EP1734933B1 (https=)
JP (1) JP2007530492A (https=)
CN (1) CN1956707B (https=)
AR (1) AR048342A1 (https=)
AT (1) ATE468846T1 (https=)
AU (1) AU2005226927B2 (https=)
BR (1) BRPI0509271A (https=)
CA (1) CA2559685A1 (https=)
DE (1) DE602005021475D1 (https=)
MY (1) MY145329A (https=)
PE (1) PE20051163A1 (https=)
RU (1) RU2375047C2 (https=)
TW (1) TW200600121A (https=)
WO (1) WO2005092295A1 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8273376B2 (en) 2006-11-17 2012-09-25 Da Volterra Colonic delivery of metallo-dependent enzymes
WO2008059062A1 (en) * 2006-11-17 2008-05-22 Da Volterra Colonic delivery using zn/pectin beads with a eudragit coating.
US20100239682A1 (en) * 2007-09-17 2010-09-23 Antoine Andremont Colonic delivery of antimicrobial agents
RU2593939C2 (ru) 2008-11-13 2016-08-10 Ногра Фарма Лимитед Антисмысловые композиции и способы их получения и применения
CA2987863A1 (en) * 2015-06-01 2016-12-08 Xeno Biosciences Inc. Methods and compositions to modulate the gut microbiota and to manage weight
CN109562158A (zh) * 2016-06-23 2019-04-02 纽特莱特公司 在动物中促进生长和提高饲料转化率的方法
EP3538659A4 (en) * 2016-11-09 2020-07-15 Engene, Inc. INTESTINAL EXPRESSION OF THE SCHEDULED DEATH LIGAND 1
JP2020502126A (ja) 2016-12-14 2020-01-23 プロジェニティ， インコーポレイテッド 消化管疾病のｊａｋ阻害薬による治療
CN110430801B (zh) * 2016-12-14 2024-04-30 比奥拉治疗股份有限公司 使用tnf抑制剂治疗胃肠道疾病
US20200253506A1 (en) * 2016-12-14 2020-08-13 Progenity, Inc. Treatment of a disease of the gastrointestinal tract with an integrin inhibitor
CN108968074B (zh) * 2018-06-06 2021-09-28 福建省农业科学院农业工程技术研究所 一种结肠靶向递送的银耳糖醛酸多糖-芙蓉李花青素复合物及其制备方法
KR102104507B1 (ko) * 2019-08-23 2020-04-24 브릿지바이오테라퓨틱스(주) 팔미토일-l-프롤릴-l-프롤릴-글리실-l-타이로신 나트륨을 포함하는 약제학적 제제 및 이의 제조방법
ES3014076T3 (en) 2020-03-26 2025-04-16 Nutrivert Inc Lipophilic enantiomers of desacetylglucosamine muramyl dipeptide with anti-inflammatory and growth promoting activity

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2113221C1 (ru) * 1990-05-04 1998-06-20 Ииссум Рисерч Дивелопмент Компани оф дзе Хебрю Юниверсити оф Иеруcалим Фармацевтическая форма для введения лекарственного средства в ободочную кишку, способ введения лекарственного препарата и способ получения матриц для такой формы

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2773959B2 (ja) * 1990-07-10 1998-07-09 信越化学工業株式会社 大腸内放出性固形製剤
SI9011830B (sl) * 1990-09-27 1999-12-31 Univerza V Ljubljani, Fakulteta Za Farmacijo Novi N-acildipeptidi, postopki za njihovo pripravo in farmacevtski pripravki, ki jih vsebujejo
DE19732903A1 (de) * 1997-07-30 1999-02-04 Falk Pharma Gmbh Pellet-Formulierung zur Behandlung des Intestinaltraktes
UA73092C2 (uk) * 1998-07-17 2005-06-15 Брістол-Майерс Сквібб Компані Таблетка з ентеросолюбільним покриттям і спосіб її приготування
US6627223B2 (en) * 2000-02-11 2003-09-30 Eurand Pharmaceuticals Ltd. Timed pulsatile drug delivery systems

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2113221C1 (ru) * 1990-05-04 1998-06-20 Ииссум Рисерч Дивелопмент Компани оф дзе Хебрю Юниверсити оф Иеруcалим Фармацевтическая форма для введения лекарственного средства в ободочную кишку, способ введения лекарственного препарата и способ получения матриц для такой формы

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Moriguchi M et al: "Therapeutic effects of LK 423, a phthalimido-desmuramyl-dipeptide compound, on dextran sulfate sodium inducted colitis in rodents through restoring their interleukin-10 producing capacity" ARZNEIMITTEL FORSCHUNG. DRUG RESEARCH, EDITIO CANTOR VERLAG, AULENDORF, DE, vol.49, no.1, 1999, pages 184-192. ShinEtsu NF Hypromellose Phthalate, Enteric Coating Material, http://www.metolose.jp. *

Also Published As

Publication number Publication date
EP1734933B1 (en) 2010-05-26
AR048342A1 (es) 2006-04-19
US20100183714A1 (en) 2010-07-22
WO2005092295A1 (en) 2005-10-06
CA2559685A1 (en) 2005-10-06
CN1956707A (zh) 2007-05-02
EP1734933A1 (en) 2006-12-27
BRPI0509271A (pt) 2007-09-04
ATE468846T1 (de) 2010-06-15
MY145329A (en) 2012-01-31
AU2005226927B2 (en) 2010-09-23
DE602005021475D1 (de) 2010-07-08
PE20051163A1 (es) 2006-02-21
TW200600121A (en) 2006-01-01
RU2006137660A (ru) 2008-05-10
AU2005226927A1 (en) 2005-10-06
CN1956707B (zh) 2010-12-29
JP2007530492A (ja) 2007-11-01

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Effective date: 20110325