RU2351337C1 - Способ уменьшения, стабилизации и предупреждения разрыва богатой липидами бляшки - Google Patents

Способ уменьшения, стабилизации и предупреждения разрыва богатой липидами бляшки Download PDF

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Publication number
RU2351337C1
RU2351337C1 RU2007125976/15A RU2007125976A RU2351337C1 RU 2351337 C1 RU2351337 C1 RU 2351337C1 RU 2007125976/15 A RU2007125976/15 A RU 2007125976/15A RU 2007125976 A RU2007125976 A RU 2007125976A RU 2351337 C1 RU2351337 C1 RU 2351337C1
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RU
Russia
Prior art keywords
pitavastatin
pharmaceutically acceptable
hydrate
acceptable salt
lipid
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RU2007125976/15A
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English (en)
Russian (ru)
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RU2007125976A (ru
Inventor
Хидеюки КОБАЯСИ (JP)
Хидеюки Кобаяси
Ясунобу ЙОСИНАКА (JP)
Ясунобу ЙОСИНАКА
Кимиюки СИБУЯ (JP)
Кимиюки Сибуя
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Кова Ко., Лтд.
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Publication of RU2007125976A publication Critical patent/RU2007125976A/ru
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Publication of RU2351337C1 publication Critical patent/RU2351337C1/ru

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965—Non-condensed pyrazines
    • A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
RU2007125976/15A 2004-12-10 2005-12-09 Способ уменьшения, стабилизации и предупреждения разрыва богатой липидами бляшки RU2351337C1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US63453204P 2004-12-10 2004-12-10
US60/634,532 2004-12-10

Publications (2)

Publication Number Publication Date
RU2007125976A RU2007125976A (ru) 2009-01-20
RU2351337C1 true RU2351337C1 (ru) 2009-04-10

Family

ID=36587943

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2007125976/15A RU2351337C1 (ru) 2004-12-10 2005-12-09 Способ уменьшения, стабилизации и предупреждения разрыва богатой липидами бляшки

Country Status (11)

Country Link
US (2) US20090275595A1 (https=)
EP (1) EP1827440A4 (https=)
JP (1) JP2008522955A (https=)
KR (1) KR100895031B1 (https=)
CN (1) CN101068548B (https=)
AU (1) AU2005314810B2 (https=)
CA (1) CA2590224C (https=)
NZ (1) NZ554924A (https=)
RU (1) RU2351337C1 (https=)
TW (1) TW200619204A (https=)
WO (1) WO2006064889A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20060111898A (ko) * 2003-08-29 2006-10-30 교와 가부시키가이샤 지질-풍부-플라크의 안정화 방법 및 파열 예방방법
US8048083B2 (en) * 2004-11-05 2011-11-01 Dfine, Inc. Bone treatment systems and methods
WO2011081118A1 (ja) * 2009-12-29 2011-07-07 興和株式会社 経口投与用医薬組成物
JPWO2011081117A1 (ja) * 2009-12-29 2013-05-09 興和株式会社 経口投与用固形医薬組成物

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6124309A (en) * 1995-11-02 2000-09-26 Warner-Lambert Company Method and pharmaceutical composition for regulating lipid concentration
RU2000101310A (ru) * 1997-06-16 2001-10-27 Байер Акциенгезелльшафт Способ получения лекарственных средств, содержащих ингибиторы гидроксиметилглютарил-соа-редуктазы
RU2198682C2 (ru) * 1995-06-20 2003-02-20 Такеда Кемикал Индастриз Лтд. Фармацевтическая композиция
RU2207341C2 (ru) * 1997-05-26 2003-06-27 Кова Компани, Лтд. Новые циклические соединения диамина, содержащие их лекарственные средства и способы лечения
RU2235483C2 (ru) * 1998-11-25 2004-09-10 Нутри Фарма Аса Композиция, фармацевтический препарат и способ для профилактики и/или лечения и/или ослабления сердечно-сосудистых заболеваний

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4444784A (en) * 1980-08-05 1984-04-24 Merck & Co., Inc. Antihypercholesterolemic compounds
DK149080C (da) * 1980-06-06 1986-07-28 Sankyo Co Fremgangsmaade til fremstilling af derivater af ml-236b-carboxylsyre
JP2569746B2 (ja) * 1987-08-20 1997-01-08 日産化学工業株式会社 キノリン系メバロノラクトン類
US5177080A (en) * 1990-12-14 1993-01-05 Bayer Aktiengesellschaft Substituted pyridyl-dihydroxy-heptenoic acid and its salts
US5491172A (en) * 1993-05-14 1996-02-13 Warner-Lambert Company N-acyl sulfamic acid esters (or thioesters), N-acyl sulfonamides, and N-sulfonyl carbamic acid esters (or thioesters) as hypercholesterolemic agents
US6969711B2 (en) * 1997-05-26 2005-11-29 Kowa Company, Ltd. Cyclic diamine compounds and medicine containing the same
WO2001022962A1 (en) * 1999-09-30 2001-04-05 Merck & Co., Inc. Anti-hypercholesterolemic drug combination
AU2001269516B2 (en) * 2000-07-13 2006-09-14 Takeda Pharmaceutical Company Limited Lipid-rich plaque regressing agents
WO2002020009A1 (en) * 2000-09-01 2002-03-14 Sankyo Company, Limited Medicinal compositions
US20060165605A1 (en) * 2001-12-28 2006-07-27 Ye-Mon Chen Process to regenerate fcc spent catalyst
MY140618A (en) * 2003-02-28 2009-12-31 Kowa Co Method for preparing acid addition salts of polyacidic basic compounds
US20060046996A1 (en) * 2004-08-31 2006-03-02 Kowa Co., Ltd. Method for treating hyperlipidemia

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2198682C2 (ru) * 1995-06-20 2003-02-20 Такеда Кемикал Индастриз Лтд. Фармацевтическая композиция
US6124309A (en) * 1995-11-02 2000-09-26 Warner-Lambert Company Method and pharmaceutical composition for regulating lipid concentration
RU2207341C2 (ru) * 1997-05-26 2003-06-27 Кова Компани, Лтд. Новые циклические соединения диамина, содержащие их лекарственные средства и способы лечения
RU2000101310A (ru) * 1997-06-16 2001-10-27 Байер Акциенгезелльшафт Способ получения лекарственных средств, содержащих ингибиторы гидроксиметилглютарил-соа-редуктазы
RU2235483C2 (ru) * 1998-11-25 2004-09-10 Нутри Фарма Аса Композиция, фармацевтический препарат и способ для профилактики и/или лечения и/или ослабления сердечно-сосудистых заболеваний

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
реферат базы данных PubMed: Llaverias G. et al. Avasimibeand atorvastatin synergistically reduce cholesteryl ester contene in THP-1 macrophages. Eur. J.Pharmacol. 2002 Sep 6; 451(1):11-7 [on line} PMID: 12223223 [найдено 12.09.2008]. *

Also Published As

Publication number Publication date
KR20070085508A (ko) 2007-08-27
EP1827440A1 (en) 2007-09-05
CA2590224A1 (en) 2006-06-22
WO2006064889A1 (en) 2006-06-22
AU2005314810B2 (en) 2010-08-26
NZ554924A (en) 2010-09-30
RU2007125976A (ru) 2009-01-20
CA2590224C (en) 2011-12-20
KR100895031B1 (ko) 2009-04-24
US20090275595A1 (en) 2009-11-05
CN101068548B (zh) 2010-12-08
JP2008522955A (ja) 2008-07-03
EP1827440A4 (en) 2010-12-08
US20110207742A1 (en) 2011-08-25
AU2005314810A1 (en) 2006-06-22
HK1111356A1 (en) 2008-08-08
CN101068548A (zh) 2007-11-07
TW200619204A (en) 2006-06-16

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MM4A The patent is invalid due to non-payment of fees

Effective date: 20121210