RU2322053C2 - Agent for enhancing productivity and safety of agricultural animals and poultry - Google Patents

Abstract

FIELD: veterinary science.

SUBSTANCE: invention proposes an agent comprising, wt.-%: fumaric acid, 2.0-3.5, and montmorillonite clay, the balance. Proposed agent provides correction of metabolism, it acts as a protecting agent against stress, activates processes of aerobic oxidation, normalizes energy supplying in adaptation processes, adsorbs gases, alkaloids, heavy metals and poisons actively. Use of the agent in animal husbandry and poultry farming enhances productivity in average by 9.5% and 7.5% and safety of agricultural animals and poultry by 6.1% and 6.7%, respectively.

EFFECT: valuable properties and enhanced effectiveness of agent.

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Description

The present invention relates to veterinary medicine and can be used to increase the productivity and preservation of farm animals and poultry.

A means of activating metabolic processes containing succinic acid and its pharmaceutically acceptable salt, as well as substances with vitamin action in the following ratio of components, wt.%:

Succinic acid and its salt up to 99,998 Vitamin A Substances action rest

(RF patent No. 2143265, class 6 А61К 31/19, 45/06. Bull. No. 36 dated 12/27/99).

The closest composition to enhance metabolic processes is an agent containing succinic acid or its pharmaceutically acceptable carrier, as well as a substance with an adsorbing effect. White clay can be used as a substance with an adsorbing effect in the proposed preparation (RF Patent No. 2135171, 6 A61K 31/19, 47/00. Bull. No. 24 dated 08/27/99).

As a result of the correction of metabolic processes in animals and birds, metabolic orientation of the body occurs, which has a significant effect on the level of natural resistance. The consequence of this is the activation of metabolism, leading to an increase in the productive capacity of animals and birds, their safety and productivity.

However, the known compositions do not provide sufficient efficiency of productivity and preservation of farm animals and birds.

Tasks: increasing the productivity of farm animals and poultry, keeping livestock, timely correction of metabolism, immune status, increasing the biological value of feed.

The technical solution to the problem is to increase the productivity and safety of animals and birds by creating a tool that has a stimulating effect on the metabolic processes of the body.

The problem is achieved in that in a tool for increasing productivity and preservation of animals and birds, including organic acid and clay, according to the invention, fumaric acid and montmorillonite clay are used in the following ratio of components, wt.%:

Fumaric acid 2.0-3.5 Montmorillonite Clay rest

The technical result is justified by the fact that the claimed product for animals and birds differs from the closest analogue by the presence of fumaric acid in its composition, which, in addition to the properties characteristic of succinic acid, has an antimicrobial and fungicidal effect, which prevents the development of putrefactive and conditionally pathogenic microflora in the gastrointestinal tract. intestinal tract and, in turn, contributes to the vital functions of beneficial symbiont microorganisms, such as acidophils, lactobacilli and bifidobacteria. In addition, the product contains montmorillonite clay, which, in addition to sorption, has a number of unique properties due to its crystalline structure, namely, catalytic binding activity, ductility, thermal stability and permeability. Montmorillonite contains a large complex of macro- and microelements, which are biologically active substances.

Signs that distinguish the claimed technical solution from the closest analogue are aimed at achieving the task and have not been identified in the study of this and related fields of science and technology and, therefore, meet the criterion of "inventive step".

The production name of the means for the correction of the metabolism of animals and birds, increasing their productivity and preservation, is the word formed from the abbreviation of the word montmorillonite - "Morenit".

The claimed tool "Morenit" is a complex preparation and includes components that can have a positive effect on the body of animals and birds. Each of the components of the drug is capable of performing physiological functions in a living organism. So, fumaric acid takes an active part in key reactions of structural, enzymatic and energy support. Acting as a stress protector, it activates the processes of aerobic oxidation, normalizes the energy supply of adaptation processes, the content of glycogen, pyruvate, lactate in the liver and muscles, inhibits the stress activation of lipid peroxidation and at the same time mobilizes various parts of the antioxidant system. After absorption, fumaric acid increases the body's resistance, increasing its energy capabilities in adverse factors.

Montmorillonite clay, being an active sorbent, adsorbs gases, alkaloids, heavy metals, toxins of microorganisms and mycotoxins. Moreover, it itself lacks toxic substances - arsenic, mercury, bismuth, etc.

The high absorption capacity of montmorillonite has a beneficial effect on digestion and absorption, normalizes intestinal motility and rumen functioning in ruminants. At the same time, he is able to increase the biological value of feed, “breeding” them, making feed more accessible for digestion under the influence of digestive juices, increasing the contact surface at which the catalytic activity of enzymes and the contact area of the mucous membranes of the gastrointestinal tract with chyme are enhanced. In addition, montmorillonite has a wide range of mineral composition and, acting as an active donor of macro- and microelements, not only normalizes mineral metabolism in animals and birds, but also intensifies the course of all metabolic processes due to the catalytic activity of enzyme systems, since microelements included in the composition of montmorillonite clay, they act as cofactors of many enzymes.

Directly or indirectly influencing the metabolic processes of the body, montmorillonite enhances the immunobiological reactivity of animals and birds, increasing their productivity and safety.

Morenite is obtained by mechanical mixing of its constituent components. In this case, standard fumaric acid is used, which is a white or slightly yellow, odorless crystalline powder made according to TU 2431-001-48426412-99 (LLC Rosplast Russia) and PBN grade bentonite clay powder (TU 2164-002-00136716-2001) received at OJSC Ilsky Plant Weighting - NPO Burenie.

The effectiveness of using fumaric acid and montmorillonite clay is presented in the table.

Table Justification of the content of the proposed ingredients №№ p.p. dose of fumaric acid Productivity,% Preservation,% the control experience The control Experience alive. bird alive. bird alive. Bird alive. birds one 1,0 3,1 3,5 6.8 4.6 1,5 0.9 3.2 4.0 2 1,5 3.4 2.9 6.9 5,0 1.65 1,2 3.3 4.7 3 2.0 4.0 3.4 8.5 6.7 2,3 1,5 5.5 6.0 four 2,5 3.2 4.1 9,4 7.3 2.0 1,1 5.9 6.2 5 3.0 4,5 4.0 9.8 7.7 2.0 1.4 6.4 7, C 6 3,5 3.6 2,8 10.6 8.5 1.7 1.8 6.7 7.5 7 4.0 4.0 3,5 10.5 8.0 2,4 2.2 6.7 7.2 8 4,5 3.8 4.2 10.0 7.9 2.6 1.9 5.5 6.1 Note: the control group included animals and poultry to which montmorillonite and fumaric acid were not added to the feed.

According to claim 1-8, the rest is montmorillonite, up to 100%.

Examples for receiving funds:

Example 1

They took 2.0% fumaric acid and gradually mixed with 98.0% montmorillonite clay.

Example 2

3.5% of fumaric acid was taken and mixed in stages with 96.5% of montmorillonite clay.

The proposed tool is tested on piglets.

Piglets of the control group received the main diet; in the second and third groups, in addition to food, moreton was added in the amount of 2% and 3.5% within 30 days from the moment of formation of the groups.

The results are shown in the table.

The dynamics of changes in body weight of piglets Group Number of animals, goal. Body weight at the beginning of the experiment, kg Body weight after 15 days, kg Body weight at the end of the experiment, kg The gain per experience, kg Daily average gain for experience, g % to control The control 22 20.5 ± 18 23.1 ± 0.32 29.3 ± 0.54 6.8 293 one hundred Experience (RR + 1% moraine) 23 19.9 ± 0.21 24.8 ± 0.35 30.0 ± 0.64 10.1 337 115.0 Experience (RR + 3% moraine) 23 20.7 ± 0.24 26.1 ± 0.28 32.0 ± 0.45 11.3 377 128.7

Morphological and biochemical studies of the blood of piglets found an increase in metabolic processes in the body of experimental animals, characterized by an increase in the level of total protein, glucose, calcium and phosphorus; an increase in albumin and γ-globulins towards the physiological norm.

The proposed drug has a pronounced pharmacological activity, increasing the main indicators of protein, carbohydrate, mineral metabolism, activating erythro- and hematopoiesis. Physico-chemical characteristics of moraine contribute to the intensification of metabolic processes, which has a positive effect on the productivity and preservation of animals and birds and expands the arsenal of technical means for these purposes.

Claims (1)

Means for increasing the productivity and preservation of farm animals and poultry, including organic acid and clay, characterized in that as the target ingredients the composition includes, wt.%: fumaric acid 2.0-3.5 montmorillonite clay rest