RU2283130C2 - Днк, кодирующая новый пептид rg1 - Google Patents

Днк, кодирующая новый пептид rg1 Download PDF

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Publication number
RU2283130C2
RU2283130C2 RU2002119208/15A RU2002119208A RU2283130C2 RU 2283130 C2 RU2283130 C2 RU 2283130C2 RU 2002119208/15 A RU2002119208/15 A RU 2002119208/15A RU 2002119208 A RU2002119208 A RU 2002119208A RU 2283130 C2 RU2283130 C2 RU 2283130C2
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RU
Russia
Prior art keywords
polypeptide
antibody
seq
amino acid
cells
Prior art date
Application number
RU2002119208/15A
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English (en)
Russian (ru)
Other versions
RU2002119208A (ru
Inventor
Ричард ХАРКИНЗ (US)
Ричард ХАРКИНЗ
Дебора ПАРКЕЗ (US)
Дебора ПАРКЕЗ
Гордон ПАРРИ (US)
Гордон ПАРРИ
Дуглас У. ШНЕЙДЕР (US)
Дуглас У. ШНЕЙДЕР
Ренате ШТАЙНБРЕХЕР (US)
Ренате ШТАЙНБРЕХЕР
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Шеринг Акциенгезельшафт
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Publication of RU2002119208A publication Critical patent/RU2002119208A/ru
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Publication of RU2283130C2 publication Critical patent/RU2283130C2/ru

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/08Drugs for disorders of the urinary system of the prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
RU2002119208/15A 1999-12-16 2000-12-15 Днк, кодирующая новый пептид rg1 RU2283130C2 (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US17237099P 1999-12-16 1999-12-16
US60/172,370 1999-12-16
US09/732,357 US6682902B2 (en) 1999-12-16 2000-12-07 DNA encoding a novel RG1 polypeptide
US09/732,357 2000-12-07

Publications (2)

Publication Number Publication Date
RU2002119208A RU2002119208A (ru) 2004-02-27
RU2283130C2 true RU2283130C2 (ru) 2006-09-10

Family

ID=26868022

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2002119208/15A RU2283130C2 (ru) 1999-12-16 2000-12-15 Днк, кодирующая новый пептид rg1

Country Status (32)

Country Link
US (5) US6682902B2 (https=)
EP (2) EP2048157B1 (https=)
JP (1) JP4979867B2 (https=)
KR (1) KR100752434B1 (https=)
CN (1) CN1297566C (https=)
AT (1) ATE440862T1 (https=)
AU (1) AU784674B2 (https=)
BG (1) BG65898B1 (https=)
BR (1) BR0017022A (https=)
CA (1) CA2394574A1 (https=)
CZ (1) CZ299232B6 (https=)
DE (1) DE60042836D1 (https=)
DK (1) DK1237915T3 (https=)
EE (1) EE05293B1 (https=)
ES (1) ES2331106T3 (https=)
HR (1) HRP20020549B1 (https=)
HU (1) HU229001B1 (https=)
IL (2) IL150115A0 (https=)
LT (1) LT5046B (https=)
ME (1) MEP37808A (https=)
MX (1) MXPA02005914A (https=)
NO (1) NO330924B1 (https=)
NZ (1) NZ519598A (https=)
PL (1) PL207634B1 (https=)
PT (1) PT1237915E (https=)
RO (1) RO122543B1 (https=)
RS (1) RS50831B (https=)
RU (1) RU2283130C2 (https=)
SI (2) SI1237915T1 (https=)
SK (2) SK286384B6 (https=)
WO (1) WO2001044291A2 (https=)
ZA (1) ZA200205638B (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2464275C2 (ru) * 2007-02-21 2012-10-20 Онкотерапи Сайенс, Инк. Пептидные вакцины для раков, экспрессирующих опухолеспецифические антигены
US8383590B2 (en) 2007-02-21 2013-02-26 Oncotherapy Science, Inc. Peptide vaccines for cancers expressing tumor-associated antigens

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EP1251139A3 (en) * 1998-04-08 2002-12-18 Genentech, Inc. Human mindin-like protein and nucleic acids encoding it
US20020161199A1 (en) * 1998-04-08 2002-10-31 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumor
US6960433B1 (en) 1998-10-19 2005-11-01 Diadexus, Inc. Method of diagnosing, monitoring, staging, imaging and treating prostate cancer
US20070031901A1 (en) * 1999-03-08 2007-02-08 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumor
US6682902B2 (en) * 1999-12-16 2004-01-27 Schering Aktiengesellschaft DNA encoding a novel RG1 polypeptide
GT200400138A (es) * 2003-07-22 2005-03-22 Anticuerpos rgi y uso de los mismos.
US7294704B2 (en) * 2003-08-15 2007-11-13 Diadexus, Inc. Pro108 antibody compositions and methods of use and use of Pro108 to assess cancer risk
US7785591B2 (en) 2004-10-14 2010-08-31 Morphosys Ag Identification and characterization of function-blocking anti-ED-B-fibronectin antibodies
BRPI0819765A2 (pt) * 2007-11-30 2015-05-05 Bristol Myers Squibb Co Conjugados de anticorpos anti-rg-1
CN102346184B (zh) * 2010-08-03 2014-03-26 中国人民解放军军事医学科学院生物工程研究所 Spon2的新用途
DE102012016127A1 (de) 2011-08-31 2013-02-28 Daniel Elias Bioaktive, regenerative Mischung zur Herstellung eines Ergänzungsnahrungsmittels

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US5206344A (en) 1985-06-26 1993-04-27 Cetus Oncology Corporation Interleukin-2 muteins and polymer conjugation thereof
US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
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US6150584A (en) * 1990-01-12 2000-11-21 Abgenix, Inc. Human antibodies derived from immunized xenomice
US5877397A (en) 1990-08-29 1999-03-02 Genpharm International Inc. Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
ATE300615T1 (de) 1990-08-29 2005-08-15 Genpharm Int Transgene mäuse fähig zur produktion heterologer antikörper
JPH08502950A (ja) 1992-05-14 1996-04-02 リボザイム・ファーマシューティカルズ・インコーポレイテッド 癌増殖を抑制する方法及び試薬
US5871969A (en) 1996-02-12 1999-02-16 Human Genome Sciences, Inc. Nucleic acids encoding human neuronal attachment factor-1
US6287777B1 (en) * 1996-05-10 2001-09-11 Beth Israel Deaconess Medical Center NPG-1 gene that is differentially expressed in prostate tumors
US6177244B1 (en) * 1996-05-10 2001-01-23 Beth Israel Deaconess Medical Center Inc. NPG-1 gene that is differentially expressed in prostate tumors
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JP3494529B2 (ja) * 1996-06-06 2004-02-09 Ykk株式会社 一体成形面ファスナー
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WO1998045442A2 (en) 1997-04-10 1998-10-15 Zymogenetics, Inc. Secreted f-spondin homologs
CA2289116A1 (en) * 1997-05-06 1998-11-12 Human Genome Sciences, Inc. Enterococcus faecalis polynucleotides and polypeptides
JP2001500386A (ja) 1997-05-09 2001-01-16 スミスクライン ビーチャム コーポレーション インテグリンリガンドであるヒトMindin
JP3868740B2 (ja) 1998-03-10 2007-01-17 ジェネンテック・インコーポレーテッド 新規なポリペプチド及びそれをコードする核酸
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US6960433B1 (en) * 1998-10-19 2005-11-01 Diadexus, Inc. Method of diagnosing, monitoring, staging, imaging and treating prostate cancer
EP1126877A4 (en) * 1998-10-19 2003-05-28 Diadexus Inc METHOD OF DIAGNOSIS, MONITORING, STADIUM CLASSIFICATION, VISUALIZATION AND TREATMENT OF PROSTATE CANCER
US6682736B1 (en) * 1998-12-23 2004-01-27 Abgenix, Inc. Human monoclonal antibodies to CTLA-4
US6824780B1 (en) * 1999-10-29 2004-11-30 Genentech, Inc. Anti-tumor antibody compositions and methods of use
US6682902B2 (en) * 1999-12-16 2004-01-27 Schering Aktiengesellschaft DNA encoding a novel RG1 polypeptide

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2464275C2 (ru) * 2007-02-21 2012-10-20 Онкотерапи Сайенс, Инк. Пептидные вакцины для раков, экспрессирующих опухолеспецифические антигены
US8383590B2 (en) 2007-02-21 2013-02-26 Oncotherapy Science, Inc. Peptide vaccines for cancers expressing tumor-associated antigens
US8623829B2 (en) 2007-02-21 2014-01-07 Oncotherapy Science, Inc. Peptide vaccines for cancers expressing tumor-associated antigens
US8759481B2 (en) 2007-02-21 2014-06-24 Oncotherapy Science, Inc. Peptide vaccines for cancers expressing tumor-associated antigens
US9067973B2 (en) 2007-02-21 2015-06-30 Oncotherapy Science, Inc. Peptide vaccines for cancers expressing tumor-associated antigens
US9284349B2 (en) 2007-02-21 2016-03-15 Oncotherapy Science, Inc. Peptide vaccines for cancers expressing tumor-associated antigens

Also Published As

Publication number Publication date
EP2048157B1 (en) 2012-10-10
CA2394574A1 (en) 2001-06-21
HU229001B1 (en) 2013-07-29
HUP0204224A2 (hu) 2003-03-28
IL150115A (en) 2013-11-28
NO330924B1 (no) 2011-08-22
BG106823A (bg) 2003-04-30
HRP20020549B1 (hr) 2013-09-30
RO122543B1 (ro) 2009-08-28
BR0017022A (pt) 2002-11-05
CZ299232B6 (cs) 2008-05-21
SK288147B6 (sk) 2013-12-02
SI1237915T1 (sl) 2009-12-31
US7893217B2 (en) 2011-02-22
EP1237915A2 (en) 2002-09-11
PL207634B1 (pl) 2011-01-31
US20090214422A1 (en) 2009-08-27
LT5046B (lt) 2003-08-25
EP1237915B1 (en) 2009-08-26
WO2001044291A2 (en) 2001-06-21
PL356220A1 (en) 2004-06-28
RU2002119208A (ru) 2004-02-27
US7307154B2 (en) 2007-12-11
HUP0204224A3 (en) 2004-12-28
US20020004047A1 (en) 2002-01-10
SK286384B6 (sk) 2008-08-05
ZA200205638B (en) 2003-10-15
US20040023307A1 (en) 2004-02-05
DK1237915T3 (da) 2009-11-16
KR100752434B1 (ko) 2007-08-27
YU44602A (sh) 2005-06-10
NO20022836D0 (no) 2002-06-14
DE60042836D1 (de) 2009-10-08
ATE440862T1 (de) 2009-09-15
NO20022836L (no) 2002-08-15
EP2048157A1 (en) 2009-04-15
US20090292112A1 (en) 2009-11-26
SI21140A (sl) 2003-08-31
CN1434832A (zh) 2003-08-06
BG65898B1 (bg) 2010-04-30
KR20020065575A (ko) 2002-08-13
AU3074601A (en) 2001-06-25
SK8482002A3 (en) 2003-02-04
US20040152139A1 (en) 2004-08-05
EE200200323A (et) 2003-10-15
IL150115A0 (en) 2002-12-01
EE05293B1 (et) 2010-04-15
CN1297566C (zh) 2007-01-31
US6682902B2 (en) 2004-01-27
JP4979867B2 (ja) 2012-07-18
HRP20020549A2 (en) 2004-04-30
MXPA02005914A (es) 2003-02-27
WO2001044291A3 (en) 2002-01-17
MEP37808A (en) 2011-05-10
LT2002070A (en) 2003-04-25
JP2003521244A (ja) 2003-07-15
NZ519598A (en) 2004-03-26
PT1237915E (pt) 2009-11-04
RS50831B (sr) 2010-08-31
AU784674B2 (en) 2006-05-25
ES2331106T3 (es) 2009-12-22
US7887804B2 (en) 2011-02-15

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Effective date: 20141216