RU2260426C1 - Method for preventing obstetric-gynecological diseases in sows and increasing viability in piglets - Google Patents

Abstract

FIELD: veterinary science.

SUBSTANCE: one should apply a selenium-containing preparation named selecor: it should be introduced on the 80-90^th d of swine gestation twice at 10-15-d-long interval parenterally at the dosage of 20 mg/kg animal body weight. Application of low-toxic antioxidant as selecor enables to improve functional properties of cell membranes of placental system and endometrium and increase inspecific immune resistance in sows. It, also, enables to increase fertility in sows, values of uncomplicated deliveries and puerperal period.

EFFECT: higher viability of off-spring.

2 ex, 3 tbl

Description

The invention relates to the field of animal husbandry, in particular, can be used in pig farming for the prevention of obstetric and gynecological diseases in sows and increase the viability of piglets obtained from them.

The basis of good health and high productivity of farm animals is the optimal ratio of their metabolism. However, with intensive animal husbandry, the production technology of keeping and feeding does not in many respects correspond to the physiological needs of the body. Therefore, in the conditions of modern farms, the need for the use of biologically active substances that normalize metabolism, increase the resistance of the animal organism, and improve the viability and development of offspring is increasing.

It is known the use of bis (benzoylmethyl) selenide as a means for the treatment and prevention of infectious diseases and poisoning of animals and birds, increasing their productivity and safety / 1 //

The prototype of the invention is a method of growing piglets, comprising introducing into the main diet of piglets a preparation of selenium in the form of selenopyran at the rate of 0.1-0.3 mg of selenium per 1 kg of the main diet. This food is fed to piglets from the 1st day of weaning to 105 days of age. Selenopyran before introduction into the main diet is dissolved in fat in a ratio equal to 1: (1500-25000) / 2 /.

Common disadvantages of the analogue and prototype are:

- the complexity of the manufacturing technology and application of the tools used;

- the use of expensive fats;

- low efficiency;

- high toxicity.

The technical result of the invention is to increase efficiency, expand the arsenal of means for the prevention of obstetric and gynecological diseases in sows and increase the viability of piglets.

The technical result is achieved as follows.

On 80-90 days of gestation, sows are administered parenterally selector at a dose of 20 μg / kg body weight twice with an interval of 10-15 days.

Of the many selenium compounds, the most safe and effective are organic selenium compounds, due to their lower toxicity and better bioavailability, in particular, di (3-methylpyrazolyl-4) selenide (selecor, DPSD) / 3 /.

Selekor belongs to the new generation of organo-selenium preparations containing divalent selenium, while in the other compounds it is either 4 or 6 valence.

When using selecor, the toxicity is 3-4 times lower than when using selnopyran / 2 /, and 5-6 times in comparison with the use of bis (benzoylmethyl) selenide / 1 /.

The essence of the method is illustrated by examples.

Example 1. The effectiveness of the proposed method for the prevention of obstetric and gynecological diseases in sows.

The studies were carried out on sows of large white breed of 2-5 farrowing in the conditions of the pig-breeding complex LLC-special farm \ Vishnevsky \ (Verkhnekhavsky district of Voronezh region) with their year-round maintenance-free keeping. The animals of the experimental group were injected parenterally at a dose of 20 μg / kg body weight twice on an 80-90 day of gestation with an interval of 10-15 days, and nothing was introduced into the control. All sows were constantly monitored. Take into account the duration of pregnancy, the nature of the course of childbirth.

The results of the experiment are presented in table 1.

Table 1.
Duration of gestation and indicators of the course of labor in sows Group number Duration Including stage Primary weak birth Duration of gestation, days Farrowing, min Withdrawal, min Sequential, min Goals % Selector 6 113.80 ± 0.65 193.00 ± 12.76 * 120.83 ± 10.20 72.17 ± 5.45 * - - The control 8 111.86 ± 0.59 244.00 ± 7.57 144.57 ± 9.90 99.43 ± 3.62 2 25 * P <0.05 relative to control

In the conditions of industrial-type pig farms, the smallest incidence of postpartum diseases is recorded upon delivery on 114 days and increases both with a decrease and an increase in the duration of gestation. In intact animals, the average duration of pregnancy was 111.86 ± 0.59 days (table 1). In most sows (57.14%), labor occurred on 110-112 days and only 14.3% on 114 days. In the experimental group, the average duration of pregnancy was 113.8 ± 0.65 days with a maximum at 113 and 114 days (83.3%). That is, the appointment of the selector had a pronounced effect on the course of pregnancy and ensured biological readiness of the body for childbirth. Significant differences between the animals of the experimental and control groups were also noted in the dynamics of the birth act. Normally, the duration of labor in sows should not exceed 3.5 hours (210 minutes), including the stage of fruiting - 2 hours and the last - 1.5 hours.

In animals of the control group, the average farrowing time was 244.0 ± 7.57 minutes, including the stage of fruiting 114.57 ± 9.90 minutes, and the last 99.43 ± 3.62 minutes. Primary weakness of labor (breeding more than 3 hours) was recorded in 25% of sows. In the experimental group, the average farrowing time was 193.0 ± 12.76 minutes, including the stage of fruiting 120.83 ± 10.20 minutes, and the last 72.17 ± 5.45 minutes. Thus, the application of the proposed method to pregnant sows in comparison with the basic version prevents the primary weakness of labor, reduces the total duration of farrowing by 51 minutes, the duration of the removal of piglets by 23, 74 minutes, and the time of separation of the membranes by 27, 26 minutes.

The animals were monitored during the postpartum period, incidence and fertility were taken into account.

The results are presented in table 2.

Table 2.
Incidence of sows in the early postpartum period Group number Incidence MMA Endometritis Subclinical mastitis Goals % Goals % Goals % Selector 6 - - - - 3 fifty The control 8 1 12.5 3 37.5 5 62.5

In the early postpartum period (first 72 hours), no clinical signs of diseases of the genital organs and mammary gland were found among the animals of the experimental group. However, somatic cell counts in milk indicated a latent course of mastitis in 50% of sows (Table 2).

In the control group, a pathological course of the postpartum period was observed in half of the animals. Endometritis was found in 37.5%, and MMA syndrome in 12.5% of sows. At the same time, 62.5% of sows in the mammary gland had lobes affected by subclinical mastitis.

Consequently, the use of organosulfur sows in deep-sows during vaccination normalizes metabolism and creates optimal conditions for the course of the birth act and the postpartum period.

Analysis of the final data on reproduction confirmed the high prophylactic effectiveness of the proposed method. Its positive influence affected the subsequent reproductive cycle. Within 6 days after weaning, the reproductive cycle showed and inseminated 100% of the sows of the experimental group and only 85.7% of the control. Moreover, in the group where the claimed method was applied, all sows were fertilized, while in the control group 16.66% remained single. Thus, the use of the proposed method helps to reduce infertility by 28.6%.

Example 2. The influence of the proposed method on the viability of piglets.

Normalizing the metabolism of sows in the last third of gestation, the use of the proposed method has a beneficial effect on the intrauterine development and viability of the offspring (table 3).

Table 3.
Productive qualities of piglets Group Received piglets per 1 sow, goals Of these hypotrophic,% The average weight of a pig at birth, kg Daily gain Preservation,% 1-3 weeks 4-6 week Selector 9.67 ± 1.54 - 1.4 ± 0.03 * 160,4 138.0 86.21 The control 11.88 ± 0.83 13.7 1.18 ± 0.06 138.6 106.8 78.94 * P <0.05 relative to control

Despite the fact that the average number of piglets obtained from one sow in the experimental group was slightly lower than in the control (9.67 ± 0.54 versus 11.88 ± 0.83), their quality was better, or rather - the average weight of a pig at birth was 1.4 ± 0.03 kg in the experimental group and 1.18 ± 0.06 kg in the control, with 13.7% of piglets in the control group weighing below 0.8 kg, while in the group piglets whose mothers received a selenium-containing preparation were not.

It should be noted that among the piglets from the experimental group of large there were 34.5%, medium - 63.8% and only 1.7% small, while in the control group there were no large piglets, and there were 63.2% of medium and 36.8% small. Thus, the introduction of DPSD contributed to the increase in large-fruited.

The appointment of a selector to sows also contributed to the growth of suckling piglets. The average daily gain of piglets in 1-3 weeks was 160.4 g in the experimental group and 138.6 g in the control group, which is 13.6% lower. During the 4th - 6th week, the growth dynamics of the piglets of the experimental group continued to exceed that in the control by 1.3 times. Their average daily gain amounted to 138.0 g in the experiment against 106.8 g in the control. Moreover, it should be noted that after weaning 60% of the piglets in the control group weighed below 8 kg, while in the experimental piglets there were only 16.6%.

DPSD administered to mothers also affects piglet resistance to disease. During the suckling period, 16.6% of piglets fell ill with gastrointestinal diseases in the control group, and no piglet-suckling diseases were observed in the experimental group.

The safety of piglets during the suckling period was: 86.21% in the experimental group and 78.94% in the control group, and among them, more piglets died and were crushed by the uterus.

Based on the foregoing, it can be concluded that the double use of the antioxidant selector enhances immunity and allows to achieve a positive effect on the reproductive function of sows, which is associated both with an improvement in the functional properties of the membranes of the cells of the placental system and myometrium, and with an indirect effect on the reproductive system through improved metabolism and increased nonspecific resistance of the body.

The application of the proposed method allows to prevent primary weakness of childbirth by 25% due to the normalization of the onset of labor, the duration of farrowing and thereby prevents the incidence of endometritis by 37.5%, MMA by 12.5%, subclinical mastitis - by 12.5% and helps to reduce infertility by 28.6%. In addition, it provides a decrease in the number of hypotrophy in the offspring by 13.7%, and during weaning by 33.4%, the incidence of gastroenteritis by 16.6% and an increase in the business yield of piglets by 7.3%, which makes it possible to increase the growth rate of suckling pigs by 13.6%, and after weaning by 22.6%.

Studies have shown the high efficiency of the proposed method for the prevention of postpartum diseases in sows. The application of the proposed method has a positive effect on the quality of the resulting offspring and ultimately determines the intensity of growth, development of animals, health status, productivity and quality of livestock products.

Sources of information taken into account

1. Patent RU 2171110 C2, 7 IPC A 61 K 33/04, publication date 2001.07.27.

2. Patent RU 2045200 C1, 6 IPC A 23 K 1/16, publication date 1995.10.10.

3. Sanotsky I.V. Essential Selenium // Essential Selenium. Prevention and treatment of diseases. - M., 2001. - S.3-12.

Claims (1)

A method for the prevention of obstetric and gynecological diseases in sows and increasing the viability of piglets, including the use of a selenium-containing preparation, characterized in that selector is used as such a preparation according to the following scheme: sows are parenterally introduced into the sows for 80-90 days of gestation twice with an interval of 10-15 days dose of 20 mg / kg body weight.