RU2183959C2 - Применение производных к-252а для лечения расстройств периферической или центральной нервной системы и избыточной выработки цитокина - Google Patents

Применение производных к-252а для лечения расстройств периферической или центральной нервной системы и избыточной выработки цитокина Download PDF

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RU2183959C2
RU2183959C2 RU99101117/14A RU99101117A RU2183959C2 RU 2183959 C2 RU2183959 C2 RU 2183959C2 RU 99101117/14 A RU99101117/14 A RU 99101117/14A RU 99101117 A RU99101117 A RU 99101117A RU 2183959 C2 RU2183959 C2 RU 2183959C2
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compound
neurons
mammal
disease
administering
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RU99101117A (ru
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Томас М. Энгбер
Форрест А. Хаун
Майкл С. Сапорито
Лайза Д. Эймон
Мэттью С. Миллер
Эрнест мл. Найт
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Сефалон, Инк.
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
    • A—HUMAN NECESSITIES
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
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  • Immunology (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Otolaryngology (AREA)
  • Psychology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
RU99101117/14A 1996-06-25 1997-06-24 Применение производных к-252а для лечения расстройств периферической или центральной нервной системы и избыточной выработки цитокина RU2183959C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2040696P 1996-06-25 1996-06-25
US60/020,406 1996-06-25

Publications (2)

Publication Number Publication Date
RU99101117A RU99101117A (ru) 2000-12-10
RU2183959C2 true RU2183959C2 (ru) 2002-06-27

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RU99101117/14A RU2183959C2 (ru) 1996-06-25 1997-06-24 Применение производных к-252а для лечения расстройств периферической или центральной нервной системы и избыточной выработки цитокина

Country Status (16)

Country Link
US (1) US6184217B1 (https=)
EP (1) EP0912184B1 (https=)
JP (2) JP2000514420A (https=)
CN (1) CN1108799C (https=)
AT (1) ATE224718T1 (https=)
AU (1) AU721942B2 (https=)
BR (1) BR9710693A (https=)
DE (1) DE69715862T2 (https=)
DK (1) DK0912184T3 (https=)
ES (1) ES2184106T3 (https=)
NO (1) NO317335B1 (https=)
NZ (1) NZ333441A (https=)
PT (1) PT912184E (https=)
RU (1) RU2183959C2 (https=)
UA (1) UA65542C2 (https=)
WO (1) WO1997049406A1 (https=)

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KR20010083884A (ko) 1998-10-13 2001-09-03 세파론, 인코포레이티드 눈 질환 치료제
JP2000290184A (ja) * 1999-04-01 2000-10-17 Kyowa Hakko Kogyo Co Ltd 経鼻投与製剤
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JP2018504400A (ja) 2015-01-08 2018-02-15 バイオジェン・エムエイ・インコーポレイテッドＢｉｏｇｅｎ ＭＡ Ｉｎｃ． Ｌｉｎｇｏ‐１拮抗薬及び脱髄障害の治療のための使用

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US4877776A (en) * 1987-12-24 1989-10-31 Kyowa Hakko Kogyo Co., Ltd. K-252 compounds
RU2045575C1 (ru) * 1992-01-29 1995-10-10 Государственный научно-исследовательский институт генетики и селекции промышленных микроорганизмов Рекомбинатная плазмидная днк ppr - tgatg - hil - 1 beta - tsr, обеспечивающая синтез рекомбинантного интерлейкина-1 и штамм escherichia coli - продуцент рекомбинантного интерлейкина-1 бета человека
US5461146A (en) * 1992-07-24 1995-10-24 Cephalon, Inc. Selected protein kinase inhibitors for the treatment of neurological disorders

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PT912184E (pt) 2002-12-31
UA65542C2 (uk) 2004-04-15
HK1018745A1 (en) 2000-01-07
AU3409097A (en) 1998-01-14
ES2184106T3 (es) 2003-04-01
EP0912184A1 (en) 1999-05-06
JP2000514420A (ja) 2000-10-31
ATE224718T1 (de) 2002-10-15
NO317335B1 (no) 2004-10-11
CN1108799C (zh) 2003-05-21
JP4767982B2 (ja) 2011-09-07
AU721942B2 (en) 2000-07-20
EP0912184B1 (en) 2002-09-25
NO986111D0 (no) 1998-12-23
NZ333441A (en) 1999-05-28
CN1228024A (zh) 1999-09-08
DE69715862D1 (de) 2002-10-31
DK0912184T3 (da) 2002-11-25
BR9710693A (pt) 2000-01-11
WO1997049406A1 (en) 1997-12-31
DE69715862T2 (de) 2003-04-10
JP2008189676A (ja) 2008-08-21
NO986111L (no) 1999-02-23
US6184217B1 (en) 2001-02-06

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