RU2104266C1 - Карбаматы фенилалкиламиноспиртов и способы их получения - Google Patents

Карбаматы фенилалкиламиноспиртов и способы их получения Download PDF

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Publication number
RU2104266C1
RU2104266C1 RU96113126/04A RU96113126A RU2104266C1 RU 2104266 C1 RU2104266 C1 RU 2104266C1 RU 96113126/04 A RU96113126/04 A RU 96113126/04A RU 96113126 A RU96113126 A RU 96113126A RU 2104266 C1 RU2104266 C1 RU 2104266C1
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RU
Russia
Prior art keywords
structural formula
phenylalaninol
carbamoyl
compound
benzyloxycarbonyl
Prior art date
Application number
RU96113126/04A
Other languages
English (en)
Russian (ru)
Other versions
RU96113126A (ru
Inventor
Йонг Мун Чой
Us]
Яй Кук Бьюн
Kr]
Original Assignee
Юконг Лимитед
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Publication date
Application filed by Юконг Лимитед filed Critical Юконг Лимитед
Publication of RU96113126A publication Critical patent/RU96113126A/ru
Application granted granted Critical
Publication of RU2104266C1 publication Critical patent/RU2104266C1/ru

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/20—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by nitrogen atoms not being part of nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/12—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
RU96113126/04A 1994-09-09 1995-09-06 Карбаматы фенилалкиламиноспиртов и способы их получения RU2104266C1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR1019940022798A KR100197892B1 (ko) 1994-09-09 1994-09-09 신규한 페닐알킬아미노 카바메이트 화합물과 그의 제조방법
KR1994/22798 1994-09-09
PCT/KR1995/000114 WO1996007637A1 (en) 1994-09-09 1995-09-06 Novel phenylalkylaminoalcohol carbamates and process for preparing the same

Publications (2)

Publication Number Publication Date
RU96113126A RU96113126A (ru) 1998-01-10
RU2104266C1 true RU2104266C1 (ru) 1998-02-10

Family

ID=19392447

Family Applications (1)

Application Number Title Priority Date Filing Date
RU96113126/04A RU2104266C1 (ru) 1994-09-09 1995-09-06 Карбаматы фенилалкиламиноспиртов и способы их получения

Country Status (11)

Country Link
US (1) US5955499A (e)
EP (1) EP0728129B1 (e)
JP (1) JP2680478B2 (e)
KR (1) KR100197892B1 (e)
CN (1) CN1069635C (e)
AU (1) AU700544B2 (e)
CA (1) CA2176012C (e)
DE (1) DE69513140T2 (e)
ES (1) ES2140703T3 (e)
RU (1) RU2104266C1 (e)
WO (1) WO1996007637A1 (e)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR0173862B1 (ko) * 1995-02-11 1999-04-01 조규향 O-카바모일-(d)-페닐알라닌올 화합물과 그의 약제학적으로 유용한 염 및 이들의 제조방법
US20030069630A1 (en) * 2001-03-02 2003-04-10 Robert Burgermeister Stent with radiopaque markers incorporated thereon
KR20070083826A (ko) * 2004-10-28 2007-08-24 에스케이 주식회사 우울증을 위한 부가 요법
CN101217949B (zh) 2005-06-08 2012-10-17 爱思开生物制药株式会社 治疗睡眠-清醒病症
JP5298334B2 (ja) * 2005-06-22 2013-09-25 エスケー ホルディングス カンパニー リミテッド 性機能障害を治療する方法
EA200970377A1 (ru) * 2006-10-13 2009-10-30 Янссен Фармацевтика Нв Композиции фенилалкиламинокарбамата
US8642772B2 (en) 2008-10-14 2014-02-04 Sk Biopharmaceuticals Co., Ltd. Piperidine compounds, pharmaceutical composition comprising the same and its use
BRPI1015233A2 (pt) * 2009-06-22 2018-02-20 Sk Biopharmaceuticals Co Ltd métodos para tratar ou prevenir a fadiga
US8232315B2 (en) * 2009-06-26 2012-07-31 Sk Biopharmaceuticals Co., Ltd. Methods for treating drug addiction and improving addiction-related behavior
EP2496227B1 (en) 2009-11-06 2019-05-22 SK Biopharmaceuticals Co., Ltd. Methods for treating fibromyalgia syndrome
JP5836280B2 (ja) * 2009-11-06 2015-12-24 エスケー バイオファーマスティカルズ カンパニー リミテッド 注意欠陥／多動性障害（ａｄｈｄ）の治療方法
US8623913B2 (en) * 2010-06-30 2014-01-07 Sk Biopharmaceuticals Co., Ltd. Methods for treating restless legs syndrome
US9610274B2 (en) 2010-06-30 2017-04-04 Sk Biopharmaceuticals Co., Ltd. Methods for treating bipolar disorder
CA2905457A1 (en) 2013-03-13 2014-10-09 Aerial Biopharma, Llc Treatment of cataplexy
KR102309836B1 (ko) 2013-07-18 2021-10-12 에스케이바이오팜 주식회사 비만의 치료
TWI655179B (zh) * 2014-02-28 2019-04-01 南韓商愛思開生物製藥股份有限公司 胺基羰基胺基甲酸酯化合物
US10888542B2 (en) 2014-02-28 2021-01-12 Sk Biopharmaceuticals Co., Ltd. Aminocarbonylcarbamate compounds
WO2018048871A1 (en) * 2016-09-06 2018-03-15 Jazz Pharmaceuticals International Iii Limited Solvate form of (r)-2-amino-3-phenylpropyl carbamate
US10195151B2 (en) 2016-09-06 2019-02-05 Jazz Pharmaceuticals International Iii Limited Formulations of (R)-2-amino-3-phenylpropyl carbamate
EP4316592A3 (en) 2016-10-06 2024-05-01 Axsome Malta Ltd. Carbamoyl phenylalaninol compounds and uses thereof
WO2018133703A1 (zh) * 2017-01-20 2018-07-26 苏州科睿思制药有限公司 R228060 盐酸盐的晶型及其制备方法和用途
BR112019025286A2 (pt) 2017-06-02 2020-06-23 Jazz Pharmaceuticals Ireland Limited Métodos e composições para tratamento de sonolência excessiva
AU2018312328B2 (en) 2017-07-31 2022-12-15 Jazz Pharmaceuticals Ireland Limited Carbamoyl phenylalaninol analogs and uses thereof
US11447448B2 (en) 2018-08-14 2022-09-20 Glenmark Life Sciences Limited Process for the preparation of solriamfetol and salt thereof
WO2021001457A1 (en) 2019-07-04 2021-01-07 Sandoz Ag Crystalline (r)-2-amino-3-phenylpropylcarbamate acid addition salts
US10940133B1 (en) 2020-03-19 2021-03-09 Jazz Pharmaceuticals Ireland Limited Methods of providing solriamfetol therapy to subjects with impaired renal function
IT202000013855A1 (it) 2020-06-10 2021-12-10 Flamma Spa Un processo per la purificazione del (r)-2-ammino-3-fenilpropil carbammato
KR102390194B1 (ko) 2020-08-03 2022-04-25 셀라이온바이오메드 주식회사 페닐알킬 카바메이트 화합물을 포함하는 Kca3.1채널 매개질환 치료용 조성물

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1434826A (en) * 1973-11-14 1976-05-05 Gallardo Antonio Sa Esters and carbamates of aminoalkanols

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
GB, патент, 1434826, кл. C 2 C, 1976. *

Also Published As

Publication number Publication date
AU3485695A (en) 1996-03-27
JPH09503231A (ja) 1997-03-31
EP0728129B1 (en) 1999-11-03
AU700544B2 (en) 1999-01-07
EP0728129A1 (en) 1996-08-28
CA2176012C (en) 1999-01-05
KR960010617A (ko) 1996-04-20
DE69513140T2 (de) 2000-08-17
US5955499A (en) 1999-09-21
CA2176012A1 (en) 1996-03-14
WO1996007637A1 (en) 1996-03-14
ES2140703T3 (es) 2000-03-01
DE69513140D1 (de) 1999-12-09
CN1135209A (zh) 1996-11-06
JP2680478B2 (ja) 1997-11-19
KR100197892B1 (ko) 1999-06-15
CN1069635C (zh) 2001-08-15

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Effective date: 20120425