RU2020139283A - Стабильная композиция белка иммуноглобулина с двойными вариабельными доменами - Google Patents

Стабильная композиция белка иммуноглобулина с двойными вариабельными доменами Download PDF

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RU2020139283A
RU2020139283A RU2020139283A RU2020139283A RU2020139283A RU 2020139283 A RU2020139283 A RU 2020139283A RU 2020139283 A RU2020139283 A RU 2020139283A RU 2020139283 A RU2020139283 A RU 2020139283A RU 2020139283 A RU2020139283 A RU 2020139283A
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dvd
protein
composition
composition according
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RU2020139283A
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Михаэль ЗИДЛЕР
Винеет Кумар
Рави Чари
Сонал САЛУЙА
Вишвеш ПАТИЛ
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Эббви Инк.
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C07K16/245—IL-1
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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39591—Stabilisation, fragmentation
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
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    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
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    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
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    • C07K16/2875—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154
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  • Molecular Biology (AREA)
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  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Oncology (AREA)
  • Rheumatology (AREA)
  • Inorganic Chemistry (AREA)
  • Endocrinology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hematology (AREA)
  • Transplantation (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
RU2020139283A 2012-11-01 2013-11-01 Стабильная композиция белка иммуноглобулина с двойными вариабельными доменами RU2020139283A (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201261721364P 2012-11-01 2012-11-01
US61/721,364 2012-11-01
US201361794231P 2013-03-15 2013-03-15
US61/794,231 2013-03-15

Related Parent Applications (1)

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RU2015120605A Division RU2015120605A (ru) 2012-11-01 2013-11-01 Стабильная композиция белка иммуноглобулина с двойными вариабельными доменами

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RU2020139283A true RU2020139283A (ru) 2020-12-10

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RU2015120605A RU2015120605A (ru) 2012-11-01 2013-11-01 Стабильная композиция белка иммуноглобулина с двойными вариабельными доменами
RU2020139283A RU2020139283A (ru) 2012-11-01 2013-11-01 Стабильная композиция белка иммуноглобулина с двойными вариабельными доменами

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US (3) US20140161817A1 (OSRAM)
EP (2) EP3466973A1 (OSRAM)
JP (3) JP2016513069A (OSRAM)
KR (1) KR20150079866A (OSRAM)
CN (1) CN105431453A (OSRAM)
AU (3) AU2013337644A1 (OSRAM)
BR (1) BR112015009924A2 (OSRAM)
CA (1) CA2889488A1 (OSRAM)
HK (1) HK1213204A1 (OSRAM)
IL (2) IL238264A0 (OSRAM)
MX (2) MX2015005495A (OSRAM)
RU (2) RU2015120605A (OSRAM)
SG (2) SG11201503324WA (OSRAM)
TW (3) TW202033215A (OSRAM)
WO (1) WO2014071212A2 (OSRAM)

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