RU2019101011A - Полимер желатина, полученный из морских природных источников, адаптированных к холоду, и его использование - Google Patents
Полимер желатина, полученный из морских природных источников, адаптированных к холоду, и его использование Download PDFInfo
- Publication number
- RU2019101011A RU2019101011A RU2019101011A RU2019101011A RU2019101011A RU 2019101011 A RU2019101011 A RU 2019101011A RU 2019101011 A RU2019101011 A RU 2019101011A RU 2019101011 A RU2019101011 A RU 2019101011A RU 2019101011 A RU2019101011 A RU 2019101011A
- Authority
- RU
- Russia
- Prior art keywords
- amino acid
- composition according
- relative
- acid chain
- solution
- Prior art date
Links
- 229920000642 polymer Polymers 0.000 title claims 11
- 108010010803 Gelatin Proteins 0.000 title claims 2
- 229920000159 gelatin Polymers 0.000 title claims 2
- 239000008273 gelatin Substances 0.000 title claims 2
- 235000019322 gelatine Nutrition 0.000 title claims 2
- 235000011852 gelatine desserts Nutrition 0.000 title claims 2
- 150000001413 amino acids Chemical group 0.000 claims 24
- 239000000203 mixture Substances 0.000 claims 17
- 238000004132 cross linking Methods 0.000 claims 7
- PMMYEEVYMWASQN-DMTCNVIQSA-N Hydroxyproline Chemical compound O[C@H]1CN[C@H](C(O)=O)C1 PMMYEEVYMWASQN-DMTCNVIQSA-N 0.000 claims 5
- ONIBWKKTOPOVIA-BYPYZUCNSA-N L-Proline Chemical compound OC(=O)[C@@H]1CCCN1 ONIBWKKTOPOVIA-BYPYZUCNSA-N 0.000 claims 5
- ONIBWKKTOPOVIA-UHFFFAOYSA-N Proline Natural products OC(=O)C1CCCN1 ONIBWKKTOPOVIA-UHFFFAOYSA-N 0.000 claims 5
- PMMYEEVYMWASQN-UHFFFAOYSA-N dl-hydroxyproline Natural products OC1C[NH2+]C(C([O-])=O)C1 PMMYEEVYMWASQN-UHFFFAOYSA-N 0.000 claims 5
- 229960002591 hydroxyproline Drugs 0.000 claims 5
- FGMPLJWBKKVCDB-UHFFFAOYSA-N trans-L-hydroxy-proline Natural products ON1CCCC1C(O)=O FGMPLJWBKKVCDB-UHFFFAOYSA-N 0.000 claims 5
- 239000013043 chemical agent Substances 0.000 claims 4
- 238000006116 polymerization reaction Methods 0.000 claims 4
- 241000277334 Oncorhynchus Species 0.000 claims 3
- 241000277263 Salmo Species 0.000 claims 3
- 238000004519 manufacturing process Methods 0.000 claims 3
- -1 methacryloyl groups Chemical group 0.000 claims 3
- 238000000034 method Methods 0.000 claims 3
- 125000003647 acryloyl group Chemical group O=C([*])C([H])=C([H])[H] 0.000 claims 2
- 238000007385 chemical modification Methods 0.000 claims 2
- 230000001939 inductive effect Effects 0.000 claims 2
- 239000003999 initiator Substances 0.000 claims 2
- DCUFMVPCXCSVNP-UHFFFAOYSA-N methacrylic anhydride Chemical compound CC(=C)C(=O)OC(=O)C(C)=C DCUFMVPCXCSVNP-UHFFFAOYSA-N 0.000 claims 2
- 239000003505 polymerization initiator Substances 0.000 claims 2
- 239000002904 solvent Substances 0.000 claims 2
- 239000000126 substance Substances 0.000 claims 2
- 239000004094 surface-active agent Substances 0.000 claims 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 2
- 238000010146 3D printing Methods 0.000 claims 1
- 239000000654 additive Substances 0.000 claims 1
- 238000007664 blowing Methods 0.000 claims 1
- 238000005266 casting Methods 0.000 claims 1
- 238000006243 chemical reaction Methods 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 238000001523 electrospinning Methods 0.000 claims 1
- 238000005516 engineering process Methods 0.000 claims 1
- 238000001125 extrusion Methods 0.000 claims 1
- 238000001914 filtration Methods 0.000 claims 1
- 235000013305 food Nutrition 0.000 claims 1
- 238000007306 functionalization reaction Methods 0.000 claims 1
- 238000001879 gelation Methods 0.000 claims 1
- 239000008187 granular material Substances 0.000 claims 1
- 125000003588 lysine group Chemical group [H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])(N([H])[H])C(*)=O 0.000 claims 1
- 239000003658 microfiber Substances 0.000 claims 1
- 239000002121 nanofiber Substances 0.000 claims 1
- 230000000379 polymerizing effect Effects 0.000 claims 1
- 238000009987 spinning Methods 0.000 claims 1
- 239000007921 spray Substances 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L89/00—Compositions of proteins; Compositions of derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L89/00—Compositions of proteins; Compositions of derivatives thereof
- C08L89/04—Products derived from waste materials, e.g. horn, hoof or hair
- C08L89/06—Products derived from waste materials, e.g. horn, hoof or hair derived from leather or skin, e.g. gelatin
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
- A23P20/00—Coating of foodstuffs; Coatings therefor; Making laminated, multi-layered, stuffed or hollow foodstuffs
- A23P20/10—Coating with edible coatings, e.g. with oils or fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/222—Gelatin
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B33—ADDITIVE MANUFACTURING TECHNOLOGY
- B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
- B33Y70/00—Materials specially adapted for additive manufacturing
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08H—DERIVATIVES OF NATURAL MACROMOLECULAR COMPOUNDS
- C08H1/00—Macromolecular products derived from proteins
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J3/00—Processes of treating or compounding macromolecular substances
- C08J3/02—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques
- C08J3/03—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques in aqueous media
- C08J3/075—Macromolecular gels
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K5/00—Use of organic ingredients
- C08K5/04—Oxygen-containing compounds
- C08K5/10—Esters; Ether-esters
- C08K5/101—Esters; Ether-esters of monocarboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L71/00—Compositions of polyethers obtained by reactions forming an ether link in the main chain; Compositions of derivatives of such polymers
- C08L71/02—Polyalkylene oxides
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L89/00—Compositions of proteins; Compositions of derivatives thereof
- C08L89/04—Products derived from waste materials, e.g. horn, hoof or hair
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09H—PREPARATION OF GLUE OR GELATINE
- C09H7/00—Preparation of water-insoluble gelatine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/461—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from fish
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2389/00—Characterised by the use of proteins; Derivatives thereof
- C08J2389/04—Products derived from waste materials, e.g. horn, hoof or hair
- C08J2389/06—Products derived from waste materials, e.g. horn, hoof or hair derived from leather or skin
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L2312/00—Crosslinking
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Manufacturing & Machinery (AREA)
- Dispersion Chemistry (AREA)
- Dermatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Food Science & Technology (AREA)
- Materials For Medical Uses (AREA)
- Medicinal Preparation (AREA)
- Artificial Filaments (AREA)
- Polymerisation Methods In General (AREA)
- Peptides Or Proteins (AREA)
- Macromonomer-Based Addition Polymer (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- General Preparation And Processing Of Foods (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Processes Of Treating Macromolecular Substances (AREA)
- Wood Science & Technology (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16175153.2 | 2016-06-17 | ||
| EP16175153 | 2016-06-17 | ||
| PCT/IB2017/053637 WO2017216780A1 (en) | 2016-06-17 | 2017-06-19 | Gelatin polymer derived from natural sources of cold-adapted marine species and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2019101011A true RU2019101011A (ru) | 2020-07-17 |
| RU2019101011A3 RU2019101011A3 (enExample) | 2020-10-06 |
Family
ID=56368780
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2019101011A RU2019101011A (ru) | 2016-06-17 | 2017-06-19 | Полимер желатина, полученный из морских природных источников, адаптированных к холоду, и его использование |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US11566133B2 (enExample) |
| EP (1) | EP3472229B1 (enExample) |
| JP (1) | JP2019525990A (enExample) |
| KR (1) | KR20190086655A (enExample) |
| CN (1) | CN109952341A (enExample) |
| AU (1) | AU2017285384A1 (enExample) |
| CA (1) | CA3028114A1 (enExample) |
| CL (3) | CL2018003648A1 (enExample) |
| IL (1) | IL263733A (enExample) |
| RU (1) | RU2019101011A (enExample) |
| WO (1) | WO2017216780A1 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018131003A1 (en) | 2017-01-16 | 2018-07-19 | Cells For Cells, S.A | Composition comprising a substantially pure population of multipotent stromal cells encapsulated in platelet-poor plasma (ppp) |
| IL280880B2 (en) | 2018-08-27 | 2025-04-01 | Regeneron Pharma | Using Raman Spectroscopy in Downstream Purification |
| EP3719057A1 (en) | 2019-04-03 | 2020-10-07 | Tessenderlo Group NV | A gelatin and uses thereof |
| US12180374B2 (en) | 2019-06-18 | 2024-12-31 | University Of Washington | Protein-based resins for additive manufacturing |
| US20220331477A1 (en) * | 2019-09-18 | 2022-10-20 | National Institute For Materials Science | Biological tissue adhesive sheet, biological tissue reinforcement material kit, and method for producing biological tissue adhesive sheet |
| JP7604801B2 (ja) * | 2019-12-19 | 2024-12-24 | ａｒｔｉｅｎｃｅ株式会社 | 細胞培養用インクジェットインキ、細胞培養用部材及びその製造方法、細胞培養パターンの形成方法 |
| KR102463107B1 (ko) * | 2020-07-14 | 2022-11-03 | 바오밥헬스케어 주식회사 | 줄기세포 대량생산용 배양배드 및 이의 제조 방법 |
| CN112071660B (zh) * | 2020-08-03 | 2021-08-24 | 陕西国防工业职业技术学院 | 一种超长聚吡咯纳米线型电极材料的制备方法 |
| CN112679593B (zh) * | 2020-12-28 | 2023-01-03 | 华中农业大学 | 酸处理结合壳聚糖絮凝回收鱼糜漂洗液中的肌浆蛋白的方法及应用 |
| US20240368447A1 (en) * | 2021-07-16 | 2024-11-07 | The Regents Of The University Of California | Reusable environmentally friendly food cooling technology |
| EP4582439A1 (en) | 2022-09-01 | 2025-07-09 | Cells For Cells S.A. | Method for obtainingmethod for obtaining a porous injectable scaffold based on similar biopolymers with different melting temperatures |
| WO2024113021A1 (en) * | 2022-12-02 | 2024-06-06 | Gelomics Pty Ltd | Modified gelatins, hydrogels, and processes for their production |
| DE102023120769A1 (de) | 2023-08-04 | 2025-02-06 | Cellbricks Gmbh | Verfahren zur herstellung einer tinte für den 3d-druck unter verwendung eines polypeptids auf basis von menschlichem kollagen mit reduziertem hydroxyprolin-anteil |
| CN117045846A (zh) * | 2023-08-21 | 2023-11-14 | 天津工业大学 | 一种高分子量壳聚糖皮芯结构微纳米纤维敷料 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2124537C1 (ru) | 1996-07-04 | 1999-01-10 | Научно-исследовательский институт военной медицины | Композиция и способ изготовления контактной линзы |
| JPH10195169A (ja) | 1997-01-13 | 1998-07-28 | Showa Denko Kk | 重合性を付与した天然有機高分子化合物の製造方法 |
| US6458386B1 (en) | 1997-06-03 | 2002-10-01 | Innogenetics N.V. | Medicaments based on polymers composed of methacrylamide-modified gelatin |
| FR2839658B1 (fr) * | 2002-05-17 | 2004-08-06 | Protex | Nouveau procede de preparation de microcapsules a base de gelatine, contenant un liquide hydrophobe et microcapsules obtenues |
| CA2393720C (en) | 2002-07-12 | 2010-09-14 | Eli Lilly And Company | Crystalline 2,5-dione-3-(1-methyl-1h-indol-3-yl)-4-[1-(pyridin-2-ylmethyl)piperidin-4-yl]-1h-indol-3-yl]-1h-pyrrole mono-hydrochloride |
| AT501700B1 (de) | 2005-04-14 | 2011-03-15 | Univ Wien Tech | Mit strahlung härtbare, biologisch abbaubare zusammensetzungen und deren verwendung als stützmaterialien für den knochenersatz |
| EP2120971B1 (en) | 2006-12-04 | 2017-10-04 | Johns Hopkins University | Imidated biopolymer adhesive and hydrogel |
| EP1961414A1 (en) | 2007-02-21 | 2008-08-27 | FUJIFILM Manufacturing Europe B.V. | A controlled release composition comprising a recombinant gelatin |
| EP1961411A1 (en) | 2007-02-21 | 2008-08-27 | FUJIFILM Manufacturing Europe B.V. | A controlled release composition |
| CA2728187C (en) | 2008-06-18 | 2014-04-29 | Lifebond Ltd | Improved cross-linked compositions |
| GB0907323D0 (en) | 2009-04-29 | 2009-06-10 | Dynea Oy | Composite material comprising crosslinkable resin of proteinous material |
| US8658711B2 (en) * | 2010-09-29 | 2014-02-25 | Rutgers, The State University Of New Jersey | Process for the synthesis of methacrylate-derivatized type-1 collagen and derivatives thereof |
| GB201305281D0 (en) * | 2013-03-22 | 2013-05-01 | Univ Leeds | Improvements in and relating to collagen based materials |
| CN103319729B (zh) * | 2013-06-04 | 2015-10-28 | 武汉工程大学 | 一种功能明胶改性的方法 |
| RU2564824C1 (ru) | 2014-07-11 | 2015-10-10 | Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Мордовский государственный университет им. Н.П. Огарёва" | Биоразлагаемая пленка |
| CN104448161B (zh) * | 2014-12-05 | 2017-02-22 | 四川大学 | 一种改性明胶纳米微球交联的有机复合水凝胶及其制备方法 |
| AU2016337557A1 (en) | 2015-10-13 | 2018-05-31 | Francisca ALCAYAGA | Anti-angiogenic therapy based on exosomes derived from menstrual stem cells |
| EP3361986B1 (en) | 2015-10-14 | 2021-01-06 | Universidad de los Andes | Automated fabrication of layer-by-layer tissue engineered complex tubes |
| WO2017064670A2 (en) | 2015-10-14 | 2017-04-20 | Cells For Cells, S.P.A. | Treatment for infection composed of menstrual stem cells |
| WO2018131003A1 (en) | 2017-01-16 | 2018-07-19 | Cells For Cells, S.A | Composition comprising a substantially pure population of multipotent stromal cells encapsulated in platelet-poor plasma (ppp) |
-
2017
- 2017-06-19 KR KR1020197001664A patent/KR20190086655A/ko not_active Ceased
- 2017-06-19 AU AU2017285384A patent/AU2017285384A1/en not_active Abandoned
- 2017-06-19 US US16/310,780 patent/US11566133B2/en active Active
- 2017-06-19 RU RU2019101011A patent/RU2019101011A/ru not_active Application Discontinuation
- 2017-06-19 WO PCT/IB2017/053637 patent/WO2017216780A1/en not_active Ceased
- 2017-06-19 EP EP17734143.5A patent/EP3472229B1/en active Active
- 2017-06-19 JP JP2019518590A patent/JP2019525990A/ja active Pending
- 2017-06-19 CA CA3028114A patent/CA3028114A1/en not_active Abandoned
- 2017-06-19 CN CN201780050860.8A patent/CN109952341A/zh active Pending
-
2018
- 2018-12-16 IL IL263733A patent/IL263733A/en unknown
- 2018-12-17 CL CL2018003648A patent/CL2018003648A1/es unknown
-
2021
- 2021-03-26 CL CL2021000763A patent/CL2021000763A1/es unknown
- 2021-03-26 CL CL2021000762A patent/CL2021000762A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CL2021000763A1 (es) | 2021-10-22 |
| US20190194460A1 (en) | 2019-06-27 |
| AU2017285384A1 (en) | 2019-02-07 |
| CA3028114A1 (en) | 2017-12-21 |
| KR20190086655A (ko) | 2019-07-23 |
| CN109952341A (zh) | 2019-06-28 |
| EP3472229A1 (en) | 2019-04-24 |
| CL2021000762A1 (es) | 2021-10-22 |
| US11566133B2 (en) | 2023-01-31 |
| RU2019101011A3 (enExample) | 2020-10-06 |
| CL2018003648A1 (es) | 2019-05-31 |
| WO2017216780A1 (en) | 2017-12-21 |
| IL263733A (en) | 2019-01-31 |
| EP3472229B1 (en) | 2022-02-16 |
| JP2019525990A (ja) | 2019-09-12 |
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