RU2018136877A - Способы раннего вмешательства для профилактики или улучшения состояния токсичности - Google Patents
Способы раннего вмешательства для профилактики или улучшения состояния токсичности Download PDFInfo
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- RU2018136877A RU2018136877A RU2018136877A RU2018136877A RU2018136877A RU 2018136877 A RU2018136877 A RU 2018136877A RU 2018136877 A RU2018136877 A RU 2018136877A RU 2018136877 A RU2018136877 A RU 2018136877A RU 2018136877 A RU2018136877 A RU 2018136877A
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- RU
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- Prior art keywords
- therapy
- treatment
- individual
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- Prior art date
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/03—Fusion polypeptide containing a localisation/targetting motif containing a transmembrane segment
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Dermatology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662311906P | 2016-03-22 | 2016-03-22 | |
| US62/311,906 | 2016-03-22 | ||
| US201662417287P | 2016-11-03 | 2016-11-03 | |
| US62/417,287 | 2016-11-03 | ||
| US201662429722P | 2016-12-02 | 2016-12-02 | |
| US62/429,722 | 2016-12-02 | ||
| PCT/US2017/023676 WO2017165571A1 (en) | 2016-03-22 | 2017-03-22 | Early intervention methods to prevent or ameliorate toxicity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2018136877A true RU2018136877A (ru) | 2020-04-22 |
Family
ID=58609964
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2018136877A RU2018136877A (ru) | 2016-03-22 | 2017-03-22 | Способы раннего вмешательства для профилактики или улучшения состояния токсичности |
Country Status (13)
| Country | Link |
|---|---|
| US (5) | US11518814B2 (enExample) |
| EP (3) | EP4545143A3 (enExample) |
| JP (3) | JP7048571B2 (enExample) |
| KR (1) | KR20190021200A (enExample) |
| CN (1) | CN109476743A (enExample) |
| AU (2) | AU2017238218B2 (enExample) |
| BR (1) | BR112018069251A2 (enExample) |
| CA (1) | CA3018588A1 (enExample) |
| ES (1) | ES2907557T3 (enExample) |
| MA (2) | MA71266A (enExample) |
| MX (1) | MX2018011480A (enExample) |
| RU (1) | RU2018136877A (enExample) |
| WO (1) | WO2017165571A1 (enExample) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4282419A1 (en) | 2012-12-20 | 2023-11-29 | Purdue Research Foundation | Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics |
| CN117427091A (zh) | 2014-10-20 | 2024-01-23 | 朱诺治疗学股份有限公司 | 用于过继细胞治疗中的给药的组合物和方法 |
| MA43377A (fr) | 2015-12-04 | 2021-05-19 | Hutchinson Fred Cancer Res | Méthodes et compositions liées à la toxicité associée à la thérapie cellulaire |
| RU2018136877A (ru) | 2016-03-22 | 2020-04-22 | СИЭТЛ ЧИЛДРЕН'С ХОСПИТАЛ (ДиБиЭй СИЭТЛ ЧИЛДРЕН'С РИСЕРЧ ИНСТИТЬЮТ) | Способы раннего вмешательства для профилактики или улучшения состояния токсичности |
| US12144850B2 (en) | 2016-04-08 | 2024-11-19 | Purdue Research Foundation | Methods and compositions for car T cell therapy |
| US20200078400A1 (en) * | 2016-12-03 | 2020-03-12 | Juno Therapeutics, Inc. | Methods for determining car-t cells dosing |
| AU2018219226B2 (en) | 2017-02-07 | 2024-12-19 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Phospholipid ether (PLE) CAR T cell tumor targeting (CTCT) agents |
| CA3053539A1 (en) | 2017-02-27 | 2018-08-30 | Juno Therapeutics, Inc. | Compositions, articles of manufacture and methods related to dosing in cell therapy |
| ES3010559T3 (en) | 2017-02-28 | 2025-04-03 | Endocyte Inc | Compositions and methods for car t cell therapy |
| WO2019089848A1 (en) | 2017-11-01 | 2019-05-09 | Juno Therapeutics, Inc. | Methods associated with tumor burden for assessing response to a cell therapy |
| KR20200116081A (ko) * | 2017-12-01 | 2020-10-08 | 주노 쎄러퓨티크스 인코퍼레이티드 | 유전자 조작된 세포의 투약 및 조절 방법 |
| US11311576B2 (en) | 2018-01-22 | 2022-04-26 | Seattle Children's Hospital | Methods of use for CAR T cells |
| WO2019156795A1 (en) | 2018-02-06 | 2019-08-15 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Fluorescein-specific cars exhibiting optimal t cell function against fl-ple labelled tumors |
| UA127519C2 (uk) * | 2018-02-16 | 2023-09-20 | Інсайт Корпорейшн | Інгібітори шляху jak1, призначені для лікування порушень, пов'язаних із цитокінами |
| CA3091674A1 (en) | 2018-02-23 | 2019-08-29 | Endocyte, Inc. | Sequencing method for car t cell therapy |
| US20210046159A1 (en) * | 2018-03-09 | 2021-02-18 | Ospedale San Raffaele S.R.L. | Il-1 antagonist and toxicity induced by cell therapy |
| KR20210013013A (ko) * | 2018-03-09 | 2021-02-03 | 카르스젠 테라퓨틱스 리미티드 | 종양 치료 방법 및 조성물 |
| US20210263045A1 (en) * | 2018-04-06 | 2021-08-26 | The Board Of Regents Of The University Of Texas System | Prediction and treatment of immunotherapeutic toxicity |
| WO2021028469A1 (en) * | 2019-08-12 | 2021-02-18 | Sitokine Limited | Compositions and methods for treating cytokine release syndrome and neurotoxicity |
| WO2021030526A1 (en) * | 2019-08-14 | 2021-02-18 | Rigel Pharmaceuticals, Inc. | Method of blocking or ameliorating cytokine release syndrome |
| KR20220163940A (ko) | 2020-02-04 | 2022-12-12 | 시애틀 칠드런즈 호스피탈 디/비/에이 시애틀 칠드런즈 리서치 인스티튜트 | 항-디니트로페놀 키메라 항원 수용체 |
| US11045546B1 (en) | 2020-03-30 | 2021-06-29 | Cytodyn Inc. | Methods of treating coronavirus infection |
| US20230366893A1 (en) * | 2020-09-29 | 2023-11-16 | Washington University | Methods to determine risk of neurotoxicity |
| JP2023552452A (ja) | 2020-12-08 | 2023-12-15 | インサイト・コーポレイション | 白斑治療用のjak1経路阻害薬 |
| EP4696710A3 (en) | 2021-05-03 | 2026-05-06 | Incyte Corporation | Jak1 pathway inhibitors for the treatment of prurigo nodularis |
| WO2026092543A1 (en) * | 2024-10-29 | 2026-05-07 | Shenzhen Genocury Biotech Co., Ltd | Methods and compositions of prophylactic therapy for preventing crs |
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| RU2018136877A (ru) | 2016-03-22 | 2020-04-22 | СИЭТЛ ЧИЛДРЕН'С ХОСПИТАЛ (ДиБиЭй СИЭТЛ ЧИЛДРЕН'С РИСЕРЧ ИНСТИТЬЮТ) | Способы раннего вмешательства для профилактики или улучшения состояния токсичности |
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-
2017
- 2017-03-22 RU RU2018136877A patent/RU2018136877A/ru not_active Application Discontinuation
- 2017-03-22 MA MA71266A patent/MA71266A/fr unknown
- 2017-03-22 CN CN201780031706.6A patent/CN109476743A/zh active Pending
- 2017-03-22 EP EP24221056.5A patent/EP4545143A3/en active Pending
- 2017-03-22 US US16/087,488 patent/US11518814B2/en active Active
- 2017-03-22 EP EP17719044.4A patent/EP3433276B1/en not_active Revoked
- 2017-03-22 MA MA044486A patent/MA44486A/fr unknown
- 2017-03-22 BR BR112018069251A patent/BR112018069251A2/pt not_active IP Right Cessation
- 2017-03-22 ES ES17719044T patent/ES2907557T3/es active Active
- 2017-03-22 WO PCT/US2017/023676 patent/WO2017165571A1/en not_active Ceased
- 2017-03-22 AU AU2017238218A patent/AU2017238218B2/en active Active
- 2017-03-22 EP EP21207779.6A patent/EP4015536A1/en active Pending
- 2017-03-22 KR KR1020187030514A patent/KR20190021200A/ko not_active Withdrawn
- 2017-03-22 JP JP2019500746A patent/JP7048571B2/ja active Active
- 2017-03-22 MX MX2018011480A patent/MX2018011480A/es unknown
- 2017-03-22 CA CA3018588A patent/CA3018588A1/en active Pending
-
2022
- 2022-03-24 JP JP2022047991A patent/JP7528143B2/ja active Active
- 2022-12-02 US US18/061,196 patent/US11760804B2/en active Active
- 2022-12-05 US US18/061,939 patent/US20230212298A1/en active Pending
-
2023
- 2023-06-06 US US18/329,987 patent/US12098208B2/en active Active
-
2024
- 2024-07-24 AU AU2024205049A patent/AU2024205049A1/en active Pending
- 2024-07-24 JP JP2024118592A patent/JP2024156736A/ja active Pending
- 2024-09-09 US US18/828,243 patent/US20240425608A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP4015536A1 (en) | 2022-06-22 |
| US20230322937A1 (en) | 2023-10-12 |
| JP2022088489A (ja) | 2022-06-14 |
| JP2019509351A (ja) | 2019-04-04 |
| MA44486A (fr) | 2019-01-30 |
| US20190112379A1 (en) | 2019-04-18 |
| ES2907557T3 (es) | 2022-04-25 |
| AU2024205049A1 (en) | 2024-08-15 |
| EP3433276B1 (en) | 2021-12-22 |
| AU2017238218A1 (en) | 2018-10-11 |
| WO2017165571A1 (en) | 2017-09-28 |
| CA3018588A1 (en) | 2017-09-28 |
| JP7048571B2 (ja) | 2022-04-05 |
| JP7528143B2 (ja) | 2024-08-05 |
| US20230212298A1 (en) | 2023-07-06 |
| EP4545143A2 (en) | 2025-04-30 |
| US11518814B2 (en) | 2022-12-06 |
| MA71266A (fr) | 2025-04-30 |
| KR20190021200A (ko) | 2019-03-05 |
| US20240425608A1 (en) | 2024-12-26 |
| JP2024156736A (ja) | 2024-11-06 |
| EP4545143A3 (en) | 2025-07-23 |
| EP3433276A1 (en) | 2019-01-30 |
| US12098208B2 (en) | 2024-09-24 |
| CN109476743A (zh) | 2019-03-15 |
| MX2018011480A (es) | 2019-03-28 |
| BR112018069251A2 (pt) | 2019-01-22 |
| US20230091447A1 (en) | 2023-03-23 |
| AU2017238218B2 (en) | 2024-05-02 |
| US11760804B2 (en) | 2023-09-19 |
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