RU2018110055A3 - - Google Patents

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Publication number
RU2018110055A3
RU2018110055A3 RU2018110055A RU2018110055A RU2018110055A3 RU 2018110055 A3 RU2018110055 A3 RU 2018110055A3 RU 2018110055 A RU2018110055 A RU 2018110055A RU 2018110055 A RU2018110055 A RU 2018110055A RU 2018110055 A3 RU2018110055 A3 RU 2018110055A3
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RU
Russia
Application number
RU2018110055A
Other languages
Russian (ru)
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RU2721419C2 (ru
RU2018110055A (ru
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed filed Critical
Publication of RU2018110055A publication Critical patent/RU2018110055A/ru
Publication of RU2018110055A3 publication Critical patent/RU2018110055A3/ru
Application granted granted Critical
Publication of RU2721419C2 publication Critical patent/RU2721419C2/ru

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/041Heterocyclic compounds
    • A61K51/044Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0455Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/041Heterocyclic compounds
    • A61K51/044Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0459Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/002Heterocyclic compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/12Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains three hetero rings
    • C07D513/14Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/05Isotopically modified compounds, e.g. labelled

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Physics & Mathematics (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nuclear Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
RU2018110055A 2015-08-28 2016-08-26 Зонды визуализации белка гентингтина RU2721419C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562211118P 2015-08-28 2015-08-28
US62/211,118 2015-08-28
PCT/US2016/049112 WO2017040336A1 (en) 2015-08-28 2016-08-26 Probes for imaging huntingtin protein

Publications (3)

Publication Number Publication Date
RU2018110055A RU2018110055A (ru) 2019-09-30
RU2018110055A3 true RU2018110055A3 (OSRAM) 2019-10-28
RU2721419C2 RU2721419C2 (ru) 2020-05-19

Family

ID=58103449

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2018110055A RU2721419C2 (ru) 2015-08-28 2016-08-26 Зонды визуализации белка гентингтина

Country Status (18)

Country Link
US (3) US10137211B2 (OSRAM)
EP (1) EP3340796B1 (OSRAM)
JP (1) JP6944929B2 (OSRAM)
CN (1) CN108135172B (OSRAM)
AU (1) AU2016315648B2 (OSRAM)
BR (1) BR112018003331B1 (OSRAM)
CA (1) CA2995847C (OSRAM)
DK (1) DK3340796T3 (OSRAM)
ES (1) ES2885053T3 (OSRAM)
HR (1) HRP20211156T1 (OSRAM)
HU (1) HUE056509T2 (OSRAM)
IL (1) IL257537B (OSRAM)
MX (1) MX382156B (OSRAM)
PL (1) PL3340796T4 (OSRAM)
PT (1) PT3340796T (OSRAM)
RU (1) RU2721419C2 (OSRAM)
SI (1) SI3340796T1 (OSRAM)
WO (1) WO2017040336A1 (OSRAM)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA037275B1 (ru) 2014-08-29 2021-03-03 Сиэйчдиай Фаундэйшн, Инк. Зонды для визуализации белка хантингтина
EP3190888B1 (en) 2014-08-29 2020-06-10 CHDI Foundation, Inc. Probes for imaging huntingtin protein
WO2016033440A1 (en) 2014-08-29 2016-03-03 Chdi Foundation, Inc. Probes for imaging huntingtin protein
EA035646B1 (ru) 2014-08-29 2020-07-21 Сиэйчдиай Фаундэйшн, Инк. Зонды для визуализации белка хантингтина
CN108135172B (zh) 2015-08-28 2021-03-30 Chdi基金会股份有限公司 用于成像亨廷顿蛋白的探针
WO2019157272A1 (en) * 2018-02-08 2019-08-15 Phraxis Inc. One piece anastomotic connector
US11389438B2 (en) 2019-02-25 2022-07-19 Chdi Foundation, Inc. Compounds for targeting mutant huntingtin protein and uses thereof
MX2022015829A (es) * 2020-06-11 2023-04-05 Chdi Foundation Inc Compuestos heterocíclicos y agentes formadores de imágenes para formar la imagen de la proteína huntingtina.

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2126636T3 (es) 1992-05-19 1999-04-01 Adir Derivados del bencimidazol con actividad antidiabetica y antiagregante plaquetaria.
AU2241400A (en) * 1999-04-06 2000-10-12 Yamanouchi Pharmaceutical Co., Ltd. Novel thiazolobenzoimidazole derivative
JP2000351782A (ja) * 1999-04-06 2000-12-19 Yamanouchi Pharmaceut Co Ltd メタボトロピックグルタメート受容体作用薬及び新規チアゾロベンゾイミダゾール誘導体
UY27003A1 (es) * 2000-11-06 2002-07-31 Schering Ag Productos radiofarmacéuticos para el diagnóstico de la enfermedad de alzheimer
US7750160B2 (en) * 2003-11-13 2010-07-06 Ambit Biosciences Corporation Isoxazolyl urea derivatives as kinase modulators
TW201018678A (en) * 2006-01-27 2010-05-16 Astrazeneca Ab Novel heteroaryl substituted benzothiazoles
FR2919610B1 (fr) * 2007-08-02 2009-10-16 Sanofi Aventis Sa Derives de n-heteroaryl-carboxamides tricycliques,leur preparation et leur application en therapeutique
EP2323697A2 (en) * 2008-07-24 2011-05-25 Siemens Medical Solutions USA, Inc. Imaging agents useful for identifying ad pathology
EP2218464A1 (en) * 2009-02-11 2010-08-18 Technische Universität München Compounds for non-invasive measurement of aggregates of amyloid peptides
JP2012521988A (ja) * 2009-03-23 2012-09-20 シーメンス メディカル ソリューションズ ユーエスエー インコーポレイテッド 神経学的障害を検知するためのイメージング剤
HK1210732A1 (en) 2012-07-11 2016-05-06 Nimbus Iris, Inc. Irak inhibitors and uses thereof
US9902702B2 (en) * 2014-07-15 2018-02-27 Bristol-Myers Squibb Company Spirocycloheptanes as inhibitors of rock
EA037275B1 (ru) 2014-08-29 2021-03-03 Сиэйчдиай Фаундэйшн, Инк. Зонды для визуализации белка хантингтина
EP3190888B1 (en) 2014-08-29 2020-06-10 CHDI Foundation, Inc. Probes for imaging huntingtin protein
WO2016033440A1 (en) 2014-08-29 2016-03-03 Chdi Foundation, Inc. Probes for imaging huntingtin protein
EA035646B1 (ru) 2014-08-29 2020-07-21 Сиэйчдиай Фаундэйшн, Инк. Зонды для визуализации белка хантингтина
CN108135172B (zh) 2015-08-28 2021-03-30 Chdi基金会股份有限公司 用于成像亨廷顿蛋白的探针

Also Published As

Publication number Publication date
RU2721419C2 (ru) 2020-05-19
BR112018003331B1 (pt) 2022-05-10
MX382156B (es) 2025-03-13
CN108135172A (zh) 2018-06-08
SI3340796T1 (sl) 2022-02-28
RU2018110055A (ru) 2019-09-30
US20190167821A1 (en) 2019-06-06
BR112018003331A2 (pt) 2018-11-06
WO2017040336A1 (en) 2017-03-09
US11344637B2 (en) 2022-05-31
JP2018531897A (ja) 2018-11-01
HRP20211156T1 (hr) 2021-12-24
ES2885053T3 (es) 2021-12-13
AU2016315648B2 (en) 2021-04-01
PT3340796T (pt) 2021-07-28
DK3340796T3 (da) 2021-07-26
CN108135172B (zh) 2021-03-30
HUE056509T2 (hu) 2022-02-28
AU2016315648A1 (en) 2018-03-29
US20170056535A1 (en) 2017-03-02
IL257537A (en) 2018-04-30
EP3340796A4 (en) 2019-05-15
US10137211B2 (en) 2018-11-27
US10765764B2 (en) 2020-09-08
IL257537B (en) 2020-08-31
PL3340796T3 (pl) 2022-02-21
CA2995847A1 (en) 2017-03-09
EP3340796B1 (en) 2021-04-21
JP6944929B2 (ja) 2021-10-06
PL3340796T4 (pl) 2022-02-21
EP3340796A1 (en) 2018-07-04
MX2018002338A (es) 2018-07-06
CA2995847C (en) 2024-05-28
US20210060187A1 (en) 2021-03-04

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