RU2018101449A - Адгезивный препарат, содержащий бисопролол - Google Patents

Адгезивный препарат, содержащий бисопролол Download PDF

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Publication number
RU2018101449A
RU2018101449A RU2018101449A RU2018101449A RU2018101449A RU 2018101449 A RU2018101449 A RU 2018101449A RU 2018101449 A RU2018101449 A RU 2018101449A RU 2018101449 A RU2018101449 A RU 2018101449A RU 2018101449 A RU2018101449 A RU 2018101449A
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RU
Russia
Prior art keywords
component
preparation containing
bisoprolol
adhesive preparation
pressure
Prior art date
Application number
RU2018101449A
Other languages
English (en)
Other versions
RU2018101449A3 (ru
RU2725071C2 (ru
Inventor
Эрико АБЕ
Ю Татикава
Сатоси АМЕЯМА
Наоко УРУСИХАРА
Дзун ИСИКУРА
Тецуя НАКАМУРА
Акира ЙОКОУТИ
Йоситака ИНОУЕ
Кадзухиро АОЯГИ
Томоя ТАНАКА
Наохиро НИСИДА
Кунихиро МИНАМИ
Original Assignee
Тоа Эйо Лтд.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Тоа Эйо Лтд. filed Critical Тоа Эйо Лтд.
Publication of RU2018101449A publication Critical patent/RU2018101449A/ru
Publication of RU2018101449A3 publication Critical patent/RU2018101449A3/ru
Application granted granted Critical
Publication of RU2725071C2 publication Critical patent/RU2725071C2/ru

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09J—ADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
    • C09J133/00—Adhesives based on homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides, or nitriles thereof; Adhesives based on derivatives of such polymers
    • C09J133/04—Homopolymers or copolymers of esters
    • C09J133/06—Homopolymers or copolymers of esters of esters containing only carbon, hydrogen and oxygen, the oxygen atom being present only as part of the carboxyl radical
    • C09J133/10—Homopolymers or copolymers of methacrylic acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09J—ADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
    • C09J11/00—Features of adhesives not provided for in group C09J9/00, e.g. additives
    • C09J11/02—Non-macromolecular additives
    • C09J11/06—Non-macromolecular additives organic
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09J—ADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
    • C09J7/00—Adhesives in the form of films or foils
    • C09J7/30—Adhesives in the form of films or foils characterised by the adhesive composition
    • C09J7/38—Pressure-sensitive adhesives [PSA]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Materials For Medical Uses (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Claims (6)

1. Адгезивный препарат, содержащий бисопролол, содержащий подложку и чувствительный к давлению адгезивный слой, сформированный на одной стороне подложки, причем чувствительный к давлению адгезивный слой содержит следующие компоненты (А) - (С):
компонент (А): полимер, полученный сополимеризацией мономерных компонентов, включая мономер, содержащий гидроксильную группу, и мономер алкил(мет)акрилата;
компонент (B): полимер, полученный сополимеризацией мономерных компонентов , включая мономер метилметакрилата и мономер бутилметакрилата; и
компонент (C): бисопролол.
2. Адгезивный препарат, содержащий бисопролол по п.1, где чувствительный к давлению адгезивный слой дополнительно содержит органический жидкий компонент.
3. Адгезивный препарат, содержащий бисопролол по п.1 или 2, где отношение содержания компонента (А) к компоненту (В) (компонент (А)/компонент (В)) составляет от 1/0,05 до 1/1 по массе.
RU2018101449A 2015-06-17 2016-06-17 Адгезивный препарат, содержащий бисопролол RU2725071C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2015-122405 2015-06-17
JP2015122405 2015-06-17
PCT/JP2016/068036 WO2016204260A1 (ja) 2015-06-17 2016-06-17 ビソプロロール含有貼付製剤

Publications (3)

Publication Number Publication Date
RU2018101449A true RU2018101449A (ru) 2019-07-18
RU2018101449A3 RU2018101449A3 (ru) 2019-10-04
RU2725071C2 RU2725071C2 (ru) 2020-06-29

Family

ID=57545924

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2018101449A RU2725071C2 (ru) 2015-06-17 2016-06-17 Адгезивный препарат, содержащий бисопролол

Country Status (10)

Country Link
US (1) US10717904B2 (ru)
EP (1) EP3311808B1 (ru)
JP (1) JP6118978B2 (ru)
CN (2) CN107921012A (ru)
CA (1) CA2989397C (ru)
ES (1) ES2899250T3 (ru)
PH (1) PH12017502296B1 (ru)
RU (1) RU2725071C2 (ru)
TW (1) TWI703196B (ru)
WO (1) WO2016204260A1 (ru)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020066188A1 (ja) * 2018-09-26 2020-04-02 ニチバン株式会社 含水系貼付剤

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2967788B2 (ja) 1990-10-15 1999-10-25 日東電工株式会社 医療用粘着テープおよび疾患治療用テープ製剤
DE10200578A1 (de) 2002-01-09 2003-07-10 Roehm Gmbh Haft- und Bindemittel für dermale oder transdermale Therapiesysteme
JP4478757B2 (ja) 2002-04-19 2010-06-09 日東電工株式会社 ビソプロロール含有貼付剤
JP4792193B2 (ja) 2002-08-28 2011-10-12 久光製薬株式会社 貼付剤
EP1652508B1 (en) 2003-07-31 2013-12-04 Hisamitsu Pharmaceutical Co., Inc. Adhesive patch
US20070158227A1 (en) * 2004-01-30 2007-07-12 Satoshi Amano Plaster enclosing packaging bag
JP5632577B2 (ja) 2005-01-31 2014-11-26 久光製薬株式会社 貼付剤
US20070140991A1 (en) 2005-12-21 2007-06-21 Prithwiraj Maitra Pressure sensitive adhesives for cosmetic applications
US8524273B2 (en) * 2006-02-28 2013-09-03 Hisamitsu Pharmaceutical Co., Inc. Transdermal absorption preparation
US20110104247A1 (en) * 2008-03-25 2011-05-05 Takeshi Ito Composition for stabilizing beta-blocker and transdermally absorbable preparation comprising the same
EP2298277A1 (en) * 2009-09-09 2011-03-23 Labtec GmbH Transdermal patch formulation
JP5665116B2 (ja) * 2009-11-20 2015-02-04 日東電工株式会社 貼付剤および貼付製剤
JP5652867B2 (ja) * 2009-11-20 2015-01-14 日東電工株式会社 医療用粘着剤組成物
WO2011118683A1 (ja) * 2010-03-25 2011-09-29 東洋化学株式会社 医用貼付剤
JP2014105205A (ja) * 2012-11-30 2014-06-09 Medical Front Co Ltd 医用貼付剤

Also Published As

Publication number Publication date
CA2989397A1 (en) 2016-12-22
CN107921012A (zh) 2018-04-17
RU2018101449A3 (ru) 2019-10-04
JP2017008037A (ja) 2017-01-12
EP3311808A1 (en) 2018-04-25
CA2989397C (en) 2023-08-01
TWI703196B (zh) 2020-09-01
EP3311808A4 (en) 2019-01-16
US10717904B2 (en) 2020-07-21
US20180194977A1 (en) 2018-07-12
CN116036049A (zh) 2023-05-02
PH12017502296A1 (en) 2018-06-11
WO2016204260A1 (ja) 2016-12-22
PH12017502296B1 (en) 2018-06-11
RU2725071C2 (ru) 2020-06-29
EP3311808B1 (en) 2021-11-10
TW201710430A (zh) 2017-03-16
ES2899250T3 (es) 2022-03-10
JP6118978B2 (ja) 2017-04-26

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