RU2017134418A3 - - Google Patents

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Publication number
RU2017134418A3
RU2017134418A3 RU2017134418A RU2017134418A RU2017134418A3 RU 2017134418 A3 RU2017134418 A3 RU 2017134418A3 RU 2017134418 A RU2017134418 A RU 2017134418A RU 2017134418 A RU2017134418 A RU 2017134418A RU 2017134418 A3 RU2017134418 A3 RU 2017134418A3
Authority
RU
Russia
Application number
RU2017134418A
Other languages
Russian (ru)
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RU2017134418A (ru
RU2762685C2 (ru
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed filed Critical
Publication of RU2017134418A publication Critical patent/RU2017134418A/ru
Publication of RU2017134418A3 publication Critical patent/RU2017134418A3/ru
Application granted granted Critical
Publication of RU2762685C2 publication Critical patent/RU2762685C2/ru

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1037Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/005Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies constructed by phage libraries
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1096Processes for the isolation, preparation or purification of DNA or RNA cDNA Synthesis; Subtracted cDNA library construction, e.g. RT, RT-PCR
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/51Complete heavy chain or Fd fragment, i.e. VH + CH1
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/515Complete light chain, i.e. VL + CL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
RU2017134418A 2011-07-12 2012-07-12 Выявление аффинно-зрелых человеческих антител RU2762685C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161506749P 2011-07-12 2011-07-12
US61/506,749 2011-07-12

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
RU2014102617A Division RU2636045C2 (ru) 2011-07-12 2012-07-12 Выявление аффинно-зрелых человеческих антител

Publications (3)

Publication Number Publication Date
RU2017134418A RU2017134418A (ru) 2019-02-07
RU2017134418A3 true RU2017134418A3 (https=) 2021-06-10
RU2762685C2 RU2762685C2 (ru) 2021-12-22

Family

ID=47506915

Family Applications (2)

Application Number Title Priority Date Filing Date
RU2014102617A RU2636045C2 (ru) 2011-07-12 2012-07-12 Выявление аффинно-зрелых человеческих антител
RU2017134418A RU2762685C2 (ru) 2011-07-12 2012-07-12 Выявление аффинно-зрелых человеческих антител

Family Applications Before (1)

Application Number Title Priority Date Filing Date
RU2014102617A RU2636045C2 (ru) 2011-07-12 2012-07-12 Выявление аффинно-зрелых человеческих антител

Country Status (11)

Country Link
US (6) US9234030B2 (https=)
EP (2) EP2731965A4 (https=)
JP (1) JP6731702B2 (https=)
KR (1) KR102139388B1 (https=)
CN (2) CN103687873B (https=)
AU (2) AU2012281078B2 (https=)
CA (1) CA2841475C (https=)
IL (2) IL230358B (https=)
MX (2) MX361600B (https=)
RU (2) RU2636045C2 (https=)
WO (1) WO2013009967A2 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103687873B (zh) * 2011-07-12 2016-10-19 埃克斯生物科技公司 鉴定亲和力成熟的人类抗体
GB2525568B (en) 2013-03-15 2020-10-14 Abvitro Llc Single cell barcoding for antibody discovery
GB201316644D0 (en) * 2013-09-19 2013-11-06 Kymab Ltd Expression vector production & High-Throughput cell screening
US10533204B2 (en) 2014-05-30 2020-01-14 National University Corporatlon University of Toyama Method for amplifying a T cell receptor (TCR) cDNA
WO2015187779A1 (en) 2014-06-03 2015-12-10 Xbiotech, Inc. Compositions and methods for treating and preventing staphylococcus aureus infections
EP3950944A1 (en) 2014-09-15 2022-02-09 AbVitro LLC High-throughput nucleotide library sequencing
US10975146B2 (en) 2018-06-29 2021-04-13 Cedars-Sinai Medical Center Interleukin-1 inhibition for combination treatment of pancreatic cancer
US20200392578A1 (en) * 2019-06-14 2020-12-17 The Regents Of The University Of California Methods of sequencing antibody chains from hybridomas and kits for practicing same

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE284897T1 (de) * 2000-03-10 2005-01-15 Large Scale Biology Corp Selfantigen-impfstoffe zur behandlung von b-zell lymphomen und sonstigen krebsen
AU2002953381A0 (en) * 2002-12-18 2003-01-09 Diatech Pty Ltd In vivo affinity maturation scheme
US20050032130A1 (en) * 2003-07-29 2005-02-10 Genentech, Inc. Neutralizing antibody assay and uses therefor
TWI333977B (en) 2003-09-18 2010-12-01 Symphogen As Method for linking sequences of interest
PE20071101A1 (es) 2005-08-31 2007-12-21 Amgen Inc Polipeptidos y anticuerpos
JP5205597B2 (ja) * 2007-06-01 2013-06-05 静岡県 1細胞レベルでの抗体遺伝子の解析・同定方法
NZ591543A (en) * 2008-09-30 2012-11-30 Abbott Lab Improved antibody libraries
ES2570460T3 (es) 2009-02-20 2016-05-18 Hoffmann La Roche Método de obtención de ácido nucleico que codifica inmunoglobulina
CN103687873B (zh) * 2011-07-12 2016-10-19 埃克斯生物科技公司 鉴定亲和力成熟的人类抗体

Also Published As

Publication number Publication date
US9670483B2 (en) 2017-06-06
EP3034513A2 (en) 2016-06-22
IL262977A (en) 2018-12-31
EP3034513B1 (en) 2020-09-02
WO2013009967A3 (en) 2013-04-04
RU2014102617A (ru) 2015-08-20
AU2012281078A1 (en) 2014-01-23
JP2014521316A (ja) 2014-08-28
US9453217B2 (en) 2016-09-27
US20160060618A1 (en) 2016-03-03
US9234030B2 (en) 2016-01-12
CN107090459A (zh) 2017-08-25
CA2841475C (en) 2021-02-09
US20200071388A1 (en) 2020-03-05
MX361600B (es) 2018-12-11
CN103687873A (zh) 2014-03-26
US20170233457A1 (en) 2017-08-17
MX2018015450A (es) 2021-11-16
KR102139388B1 (ko) 2020-07-30
US9394536B2 (en) 2016-07-19
RU2017134418A (ru) 2019-02-07
US20160362679A1 (en) 2016-12-15
EP3034513A3 (en) 2016-08-10
EP2731965A4 (en) 2015-06-03
IL262977B (en) 2020-07-30
CA2841475A1 (en) 2013-01-17
AU2012281078B2 (en) 2017-05-04
RU2762685C2 (ru) 2021-12-22
KR20140044905A (ko) 2014-04-15
IL230358B (en) 2018-11-29
AU2017210585B2 (en) 2019-07-25
WO2013009967A2 (en) 2013-01-17
AU2017210585A1 (en) 2017-08-24
RU2636045C2 (ru) 2017-11-17
EP2731965A2 (en) 2014-05-21
US20160060619A1 (en) 2016-03-03
CN103687873B (zh) 2016-10-19
JP6731702B2 (ja) 2020-07-29
US20130018173A1 (en) 2013-01-17
MX2014000431A (es) 2014-09-04

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