RU2016135555A3 - - Google Patents

Download PDF

Info

Publication number
RU2016135555A3
RU2016135555A3 RU2016135555A RU2016135555A RU2016135555A3 RU 2016135555 A3 RU2016135555 A3 RU 2016135555A3 RU 2016135555 A RU2016135555 A RU 2016135555A RU 2016135555 A RU2016135555 A RU 2016135555A RU 2016135555 A3 RU2016135555 A3 RU 2016135555A3
Authority
RU
Russia
Application number
RU2016135555A
Other languages
Russian (ru)
Other versions
RU2713179C2 (ru
RU2016135555A (ru
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of RU2016135555A publication Critical patent/RU2016135555A/ru
Publication of RU2016135555A3 publication Critical patent/RU2016135555A3/ru
Application granted granted Critical
Publication of RU2713179C2 publication Critical patent/RU2713179C2/ru

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41781,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4409Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 4, e.g. isoniazid, iproniazid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00Preparations for use in therapy

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
RU2016135555A 2014-02-21 2015-02-20 Антимитотические амиды для лечения рака и пролиферативных заболеваний RU2713179C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461942956P 2014-02-21 2014-02-21
US61/942,956 2014-02-21
PCT/US2015/016928 WO2015127284A2 (en) 2014-02-21 2015-02-20 Antimitotic amides for the treatment of cancer and proliferative disorders

Publications (3)

Publication Number Publication Date
RU2016135555A RU2016135555A (ru) 2018-03-28
RU2016135555A3 true RU2016135555A3 (OSRAM) 2018-10-05
RU2713179C2 RU2713179C2 (ru) 2020-02-04

Family

ID=52684675

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2016135555A RU2713179C2 (ru) 2014-02-21 2015-02-20 Антимитотические амиды для лечения рака и пролиферативных заболеваний

Country Status (15)

Country Link
US (4) US10016398B2 (OSRAM)
EP (1) EP3107909B1 (OSRAM)
JP (1) JP6506313B2 (OSRAM)
KR (1) KR102420508B1 (OSRAM)
CN (2) CN114634483B (OSRAM)
AU (1) AU2015218775C1 (OSRAM)
BR (1) BR112016019161B1 (OSRAM)
CA (1) CA2940237C (OSRAM)
ES (1) ES2893374T3 (OSRAM)
IL (1) IL247293B (OSRAM)
MX (1) MX390530B (OSRAM)
RU (1) RU2713179C2 (OSRAM)
SG (2) SG10202000590SA (OSRAM)
WO (1) WO2015127284A2 (OSRAM)
ZA (1) ZA201606471B (OSRAM)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6420622B1 (en) 1997-08-01 2002-07-16 3M Innovative Properties Company Medical article having fluid control film
JP6506313B2 (ja) * 2014-02-21 2019-04-24 フロスト バイオロジック,インコーポレーテッド 癌及び増殖性疾患の治療のための抗有糸分裂性アミド
CN106727583A (zh) * 2016-12-12 2017-05-31 范旭升 一种治疗舒张性心衰的药物组合物
US11377436B2 (en) * 2017-07-12 2022-07-05 The Brigham And Women's Hospital, Inc. EAAT2 enhancing molecules
US11760701B2 (en) 2018-02-27 2023-09-19 The Research Foundation For The State University Of New Yrok Difluoromethoxylation and trifluoromethoxylation compositions and methods for synthesizing same
WO2025248483A1 (ko) * 2024-05-30 2025-12-04 삼진제약주식회사 Nr2f6 억제제 및 이의 용도

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0001930D0 (en) * 2000-01-27 2000-03-22 Novartis Ag Organic compounds
BR0111280A (pt) * 2000-06-05 2003-06-10 Dong A Pharm Co Ltd Novos derivados de oxazolidinona e um processo para a preparação dos mesmos
US6995162B2 (en) * 2001-01-12 2006-02-07 Amgen Inc. Substituted alkylamine derivatives and methods of use
GB0209715D0 (en) * 2002-04-27 2002-06-05 Astrazeneca Ab Chemical compounds
MXPA06015106A (es) * 2004-06-30 2007-02-08 Novartis Ag Metodo para aumentar la susceptibilidad de los inhibidores de la peptidil-desformilasa mediante la utilizacion de inhibidores de la bomba de eflujo.
US20090156646A1 (en) * 2005-08-11 2009-06-18 Takeda Pharmaceutical Company Limited Pyridylphenol compound and use thereof
PL1984338T3 (pl) * 2006-01-31 2013-06-28 Synta Pharmaceuticals Corp Związki pirydylofenylowe do zastosowań związanych z zapaleniami i odpornością
JP2010510191A (ja) 2006-11-17 2010-04-02 スミスクライン ビーチャム コーポレーション 抗ウイルス剤としての2−カルボキシチオフェン誘導体
DE602008004650D1 (de) * 2007-04-12 2011-03-03 Hoffmann La Roche Pyrimidinderivate als inhibitoren von phosphatidylinositol-3-kinase
US20110118281A9 (en) * 2008-10-01 2011-05-19 Gary Bohnert Compounds for inflammation and immune-related uses
WO2010100475A1 (en) * 2009-03-02 2010-09-10 Astrazeneca Ab Hydroxamic acid derivatives as gram-negative antibacterial agents
ES2528485T3 (es) * 2009-09-11 2015-02-10 Amgen, Inc N-(4-((3-(2-amino-4-pirimidinil)-2-piridinil)oxi)fenil)-4-(4-metil-2-tienil)-1-ftalazinamina para su uso en el tratamiento del cáncer resistente a agentes antimitóticos
PT2563776T (pt) * 2010-04-27 2016-09-19 Calcimedica Inc Compostos que modulam o cálcio intracelular
US20130063385A1 (en) * 2010-05-14 2013-03-14 Sharp Kabushiki Kaisha Portable information terminal and method for controlling same
TWI541243B (zh) * 2010-09-10 2016-07-11 拜耳知識產權公司 經取代咪唑并嗒
JP2014503000A (ja) * 2011-01-21 2014-02-06 アッヴィ・インコーポレイテッド キナーゼのピコリンアミド阻害剤
US8748432B2 (en) * 2011-02-10 2014-06-10 Syngenta Participations Ag Microbiocidal pyrazole derivatives
JP5985611B2 (ja) * 2011-05-03 2016-09-06 シンタ ファーマシューティカルズ コーポレーション 炎症および免疫関連用途のための化合物
CA2853485A1 (en) * 2011-10-28 2013-05-02 Synta Pharmaceuticals Corp. Compounds for inflammation and immune-related uses
JP6506313B2 (ja) * 2014-02-21 2019-04-24 フロスト バイオロジック,インコーポレーテッド 癌及び増殖性疾患の治療のための抗有糸分裂性アミド

Also Published As

Publication number Publication date
CN114634483B (zh) 2024-08-13
US20200397758A1 (en) 2020-12-24
IL247293B (en) 2021-01-31
CA2940237A1 (en) 2015-08-27
IL247293A0 (en) 2016-09-29
JP2017506267A (ja) 2017-03-02
ES2893374T3 (es) 2022-02-08
WO2015127284A2 (en) 2015-08-27
EP3107909B1 (en) 2021-07-14
US20220008395A1 (en) 2022-01-13
AU2015218775A1 (en) 2016-08-25
RU2713179C2 (ru) 2020-02-04
JP6506313B2 (ja) 2019-04-24
AU2015218775C1 (en) 2020-01-16
BR112016019161A2 (OSRAM) 2017-08-15
US12383533B2 (en) 2025-08-12
CA2940237C (en) 2023-03-07
US20180325871A1 (en) 2018-11-15
CN114634483A (zh) 2022-06-17
WO2015127284A3 (en) 2015-10-15
BR112016019161B1 (pt) 2022-12-20
MX2016010877A (es) 2017-05-04
SG11201606869TA (en) 2016-09-29
US11129813B2 (en) 2021-09-28
KR20160116009A (ko) 2016-10-06
ZA201606471B (en) 2025-06-25
KR102420508B1 (ko) 2022-07-13
EP3107909A2 (en) 2016-12-28
AU2015218775B2 (en) 2019-06-20
US10016398B2 (en) 2018-07-10
US10772872B2 (en) 2020-09-15
SG10202000590SA (en) 2020-03-30
CN106068263A (zh) 2016-11-02
RU2016135555A (ru) 2018-03-28
MX390530B (es) 2025-03-20
US20170172984A1 (en) 2017-06-22

Similar Documents

Publication Publication Date Title
BR112016016552A2 (OSRAM)
BR112016017979A2 (OSRAM)
BR112016017278A2 (OSRAM)
BR112016016225A2 (OSRAM)
BR112016016602A2 (OSRAM)
BR112016016245A2 (OSRAM)
BR112016018948A2 (OSRAM)
BR112016016708A2 (OSRAM)
BR112016017337A2 (OSRAM)
BR112016013761A2 (OSRAM)
BR112016016612A2 (OSRAM)
BR112016018580A2 (OSRAM)
BR112016016689A2 (OSRAM)
BR112016018369A2 (OSRAM)
BR112016017083A2 (OSRAM)
BR112016016451A2 (OSRAM)
BR112016011585A2 (OSRAM)
BR112016019248A2 (OSRAM)
BR112016016823A2 (OSRAM)
BR112016018564A2 (OSRAM)
BR112016015666A2 (OSRAM)
BR112016017660A2 (OSRAM)
BR112016015243A2 (OSRAM)
BR112016016992A2 (OSRAM)
BR112016016268A2 (OSRAM)