RU2016133463A3 - - Google Patents
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- RU2016133463A3 RU2016133463A3 RU2016133463A RU2016133463A RU2016133463A3 RU 2016133463 A3 RU2016133463 A3 RU 2016133463A3 RU 2016133463 A RU2016133463 A RU 2016133463A RU 2016133463 A RU2016133463 A RU 2016133463A RU 2016133463 A3 RU2016133463 A3 RU 2016133463A3
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- RU
- Russia
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39591—Stabilisation, fragmentation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3061—Blood cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/567—Framework region [FR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/71—Decreased effector function due to an Fc-modification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461953035P | 2014-03-14 | 2014-03-14 | |
| US61/953,035 | 2014-03-14 | ||
| PCT/EP2015/055224 WO2015136052A1 (en) | 2014-03-14 | 2015-03-12 | Humanized antibodies with increased stability |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| RU2016133463A RU2016133463A (ru) | 2018-04-16 |
| RU2016133463A3 true RU2016133463A3 (ru) | 2018-08-16 |
| RU2684703C2 RU2684703C2 (ru) | 2019-04-11 |
Family
ID=52649047
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2016133463A RU2684703C2 (ru) | 2014-03-14 | 2015-03-12 | Гуманизированные антитела с повышенной стабильностью |
Country Status (18)
| Country | Link |
|---|---|
| US (3) | US10280222B2 (ru) |
| EP (2) | EP3572431A1 (ru) |
| JP (1) | JP6722110B2 (ru) |
| KR (1) | KR102345173B1 (ru) |
| CN (1) | CN106132989B (ru) |
| AU (1) | AU2015228815B2 (ru) |
| BR (1) | BR112016021066B1 (ru) |
| CA (1) | CA2939204C (ru) |
| DK (1) | DK3116908T3 (ru) |
| ES (1) | ES2747799T3 (ru) |
| HU (1) | HUE046308T2 (ru) |
| IL (1) | IL247371B (ru) |
| MX (1) | MX2016011748A (ru) |
| PL (1) | PL3116908T3 (ru) |
| PT (1) | PT3116908T (ru) |
| RU (1) | RU2684703C2 (ru) |
| SG (1) | SG11201606789SA (ru) |
| WO (1) | WO2015136052A1 (ru) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2770399T3 (es) | 2012-09-19 | 2020-07-01 | Innate Pharma | Agentes de unión a KIR3DL2 |
| ES2730011T3 (es) | 2013-02-20 | 2019-11-07 | Innate Pharma | Un compuesto que se une específicamente a KIR3DL2 para el uso en el tratamiento de linfoma de células T periférico |
| MX2016011748A (es) | 2014-03-14 | 2016-12-12 | Innate Pharma | Anticuerpos humanizados con estabilidad incrementada. |
| US20190248895A1 (en) | 2016-10-21 | 2019-08-15 | Innate Pharma | Treatment with anti-kir3dl2 agents |
| CN111263769B (zh) * | 2017-07-10 | 2024-01-02 | 先天制药公司 | Siglec-9中和性抗体 |
| CN108279302B (zh) * | 2017-07-11 | 2020-05-26 | 深圳市伯劳特生物制品有限公司 | 一种用于酶联免疫试剂盒的组合物以及幽门螺旋杆菌抗体谱检测试剂盒及其制备方法 |
Family Cites Families (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5567610A (en) | 1986-09-04 | 1996-10-22 | Bioinvent International Ab | Method of producing human monoclonal antibodies and kit therefor |
| US5229275A (en) | 1990-04-26 | 1993-07-20 | Akzo N.V. | In-vitro method for producing antigen-specific human monoclonal antibodies |
| JP4124480B2 (ja) * | 1991-06-14 | 2008-07-23 | ジェネンテック・インコーポレーテッド | 免疫グロブリン変異体 |
| US5776427A (en) | 1992-03-05 | 1998-07-07 | Board Of Regents, The University Of Texas System | Methods for targeting the vasculature of solid tumors |
| US6277375B1 (en) | 1997-03-03 | 2001-08-21 | Board Of Regents, The University Of Texas System | Immunoglobulin-like domains with increased half-lives |
| PT1071700E (pt) | 1998-04-20 | 2010-04-23 | Glycart Biotechnology Ag | Modificação por glicosilação de anticorpos para melhorar a citotoxicidade celular dependente de anticorpos |
| ES2694002T3 (es) | 1999-01-15 | 2018-12-17 | Genentech, Inc. | Polipéptido que comprende una región Fc de IgG1 humana variante |
| US7183387B1 (en) | 1999-01-15 | 2007-02-27 | Genentech, Inc. | Polypeptide variants with altered effector function |
| US6737056B1 (en) | 1999-01-15 | 2004-05-18 | Genentech, Inc. | Polypeptide variants with altered effector function |
| PT1914244E (pt) | 1999-04-09 | 2013-07-26 | Kyowa Hakko Kirin Co Ltd | Processo para regular a actividade de moléculas funcionais sob o ponto de vista imunológico |
| US7399595B2 (en) * | 2000-12-18 | 2008-07-15 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Means for the diagnosis and therapy of CTCL |
| EP1443961B1 (en) | 2001-10-25 | 2009-05-06 | Genentech, Inc. | Glycoprotein compositions |
| US20040132101A1 (en) | 2002-09-27 | 2004-07-08 | Xencor | Optimized Fc variants and methods for their generation |
| CA2495251C (en) | 2002-08-14 | 2018-03-06 | Macrogenics, Inc. | Fc.gamma.riib-specific antibodies and methods of use thereof |
| AU2003304145A1 (en) | 2002-10-18 | 2004-12-13 | Macrogenics, Inc. | Methods and compositions for vaccination comprising nucleic acid and/or polypeptide sequences of the genus borrelia |
| US7960512B2 (en) | 2003-01-09 | 2011-06-14 | Macrogenics, Inc. | Identification and engineering of antibodies with variant Fc regions and methods of using same |
| JP2006524039A (ja) | 2003-01-09 | 2006-10-26 | マクロジェニクス，インコーポレーテッド | 変異型Ｆｃ領域を含む抗体の同定および作製ならびにその利用法 |
| ES2619171T3 (es) * | 2003-07-24 | 2017-06-23 | Innate Pharma S.A. | Métodos y composiciones para aumentar la eficacia de anticuerpos terapéuticos utilizando compuestos para la potenciación de linfocitos NK |
| EP1697415A1 (en) | 2003-11-12 | 2006-09-06 | Biogen Idec MA Inc. | NEONATAL Fc RECEPTOR (FcRn)-BINDING POLYPEPTIDE VARIANTS, DIMERIC Fc BINDING PROTEINS AND METHODS RELATED THERETO |
| KR20070038453A (ko) | 2004-04-16 | 2007-04-10 | 마크로제닉스, 인크. | ＦｃγＲＩＩＢ-특이적 항체 및 그의 사용 방법 |
| KR101297146B1 (ko) | 2004-05-10 | 2013-08-21 | 마크로제닉스, 인크. | 인간화 ＦｃγＲＩＩＢ 특이적 항체 및 그의 사용 방법 |
| AU2005335714B2 (en) | 2004-11-10 | 2012-07-26 | Macrogenics, Inc. | Engineering Fc antibody regions to confer effector function |
| EP1888638A2 (en) | 2005-06-03 | 2008-02-20 | Genentech, Inc. | Method of producing antibodies with modified fucosylation level |
| DK1919503T3 (en) | 2005-08-10 | 2014-12-15 | Macrogenics Inc | Identification and preparation of antibodies with variant fc regions and methods of use thereof |
| AU2006301163B2 (en) * | 2005-10-14 | 2012-02-23 | Innate Pharma | Compositions and methods for treating proliferative disorders |
| AU2007226752A1 (en) | 2006-03-10 | 2007-09-20 | Macrogenics, Inc. | Identification and engineering of antibodies with variant heavy chains and methods of using same |
| EP2021029B1 (en) | 2006-05-26 | 2014-06-11 | MacroGenics, Inc. | Humanized fc gamma riib-specific antibodies and methods of use thereof |
| WO2008002933A2 (en) | 2006-06-26 | 2008-01-03 | Macrogenics, Inc. | Combination of fcgammariib antibodies and cd20-specific antibodies and methods of use thereof |
| EP2379598B1 (en) * | 2009-01-19 | 2015-03-11 | Innate Pharma | Anti-kir3d antibodies |
| CA2791658C (en) | 2010-03-04 | 2019-10-01 | Macrogenics, Inc. | Antibodies reactive with b7-h3, immunologically active fragments thereof and uses thereof |
| AU2012260601B2 (en) * | 2011-05-25 | 2018-02-01 | Innate Pharma, S.A. | Anti-KIR antibodies for the treatment of inflammatory disorders |
| AU2013320355B2 (en) | 2012-09-19 | 2018-06-14 | Innate Pharma | KIR3DL2 binding agents |
| ES2770399T3 (es) * | 2012-09-19 | 2020-07-01 | Innate Pharma | Agentes de unión a KIR3DL2 |
| ES2730011T3 (es) * | 2013-02-20 | 2019-11-07 | Innate Pharma | Un compuesto que se une específicamente a KIR3DL2 para el uso en el tratamiento de linfoma de células T periférico |
| MX2016011748A (es) | 2014-03-14 | 2016-12-12 | Innate Pharma | Anticuerpos humanizados con estabilidad incrementada. |
| US20190248895A1 (en) | 2016-10-21 | 2019-08-15 | Innate Pharma | Treatment with anti-kir3dl2 agents |
-
2015
- 2015-03-12 MX MX2016011748A patent/MX2016011748A/es unknown
- 2015-03-12 ES ES15709212T patent/ES2747799T3/es active Active
- 2015-03-12 EP EP19181885.5A patent/EP3572431A1/en active Pending
- 2015-03-12 BR BR112016021066-2A patent/BR112016021066B1/pt active IP Right Grant
- 2015-03-12 RU RU2016133463A patent/RU2684703C2/ru active
- 2015-03-12 DK DK15709212.3T patent/DK3116908T3/da active
- 2015-03-12 PT PT157092123T patent/PT3116908T/pt unknown
- 2015-03-12 SG SG11201606789SA patent/SG11201606789SA/en unknown
- 2015-03-12 HU HUE15709212A patent/HUE046308T2/hu unknown
- 2015-03-12 AU AU2015228815A patent/AU2015228815B2/en active Active
- 2015-03-12 KR KR1020167023648A patent/KR102345173B1/ko active IP Right Grant
- 2015-03-12 US US15/125,216 patent/US10280222B2/en active Active
- 2015-03-12 WO PCT/EP2015/055224 patent/WO2015136052A1/en active Application Filing
- 2015-03-12 CA CA2939204A patent/CA2939204C/en active Active
- 2015-03-12 JP JP2016556773A patent/JP6722110B2/ja active Active
- 2015-03-12 PL PL15709212T patent/PL3116908T3/pl unknown
- 2015-03-12 CN CN201580011578.XA patent/CN106132989B/zh active Active
- 2015-03-12 EP EP15709212.3A patent/EP3116908B1/en active Active
-
2016
- 2016-08-21 IL IL247371A patent/IL247371B/en active IP Right Grant
-
2019
- 2019-04-30 US US16/398,472 patent/US11066470B2/en active Active
-
2021
- 2021-07-15 US US17/376,314 patent/US20210340254A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20190276536A1 (en) | 2019-09-12 |
| CN106132989B (zh) | 2020-06-19 |
| BR112016021066B1 (pt) | 2024-01-02 |
| EP3572431A1 (en) | 2019-11-27 |
| US11066470B2 (en) | 2021-07-20 |
| BR112016021066A2 (pt) | 2018-01-23 |
| PL3116908T3 (pl) | 2020-01-31 |
| AU2015228815A1 (en) | 2016-09-01 |
| IL247371B (en) | 2021-06-30 |
| US10280222B2 (en) | 2019-05-07 |
| AU2015228815B2 (en) | 2020-08-27 |
| CA2939204A1 (en) | 2015-09-17 |
| RU2016133463A (ru) | 2018-04-16 |
| JP6722110B2 (ja) | 2020-07-15 |
| IL247371A0 (en) | 2016-11-30 |
| DK3116908T3 (da) | 2019-10-07 |
| MX2016011748A (es) | 2016-12-12 |
| PT3116908T (pt) | 2019-10-09 |
| ES2747799T3 (es) | 2020-03-11 |
| JP2017510569A (ja) | 2017-04-13 |
| KR20170002368A (ko) | 2017-01-06 |
| US20170158763A1 (en) | 2017-06-08 |
| HUE046308T2 (hu) | 2020-02-28 |
| EP3116908A1 (en) | 2017-01-18 |
| US20210340254A1 (en) | 2021-11-04 |
| CA2939204C (en) | 2023-06-27 |
| CN106132989A (zh) | 2016-11-16 |
| KR102345173B1 (ko) | 2021-12-29 |
| WO2015136052A1 (en) | 2015-09-17 |
| SG11201606789SA (en) | 2016-09-29 |
| EP3116908B1 (en) | 2019-06-26 |
| RU2684703C2 (ru) | 2019-04-11 |