RU2016122123A - Устройство для доставки лекарственного средства - Google Patents
Устройство для доставки лекарственного средства Download PDFInfo
- Publication number
- RU2016122123A RU2016122123A RU2016122123A RU2016122123A RU2016122123A RU 2016122123 A RU2016122123 A RU 2016122123A RU 2016122123 A RU2016122123 A RU 2016122123A RU 2016122123 A RU2016122123 A RU 2016122123A RU 2016122123 A RU2016122123 A RU 2016122123A
- Authority
- RU
- Russia
- Prior art keywords
- drive unit
- unit according
- drum
- piston rod
- housing
- Prior art date
Links
- 239000002184 metal Substances 0.000 claims 4
- 238000012377 drug delivery Methods 0.000 claims 2
- 239000012530 fluid Substances 0.000 claims 1
- 230000003993 interaction Effects 0.000 claims 1
- 229920002994 synthetic fiber Polymers 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31501—Means for blocking or restricting the movement of the rod or piston
- A61M5/31505—Integral with the syringe barrel, i.e. connected to the barrel so as to make up a single complete piece or unit
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
- A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
- A61M5/31551—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe including axial movement of dose setting member
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
- A61M5/31578—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod
- A61M5/3158—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod performed by axially moving actuator operated by user, e.g. an injection button
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M2005/2485—Ampoule holder connected to rest of syringe
- A61M2005/2488—Ampoule holder connected to rest of syringe via rotation, e.g. threads or bayonet
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M2005/2485—Ampoule holder connected to rest of syringe
- A61M2005/2492—Ampoule holder connected to rest of syringe via snap connection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2207/00—Methods of manufacture, assembly or production
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/3146—Priming, e.g. purging, reducing backlash or clearance
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/3159—Dose expelling manners
- A61M5/31593—Multi-dose, i.e. individually set dose repeatedly administered from the same medicament reservoir
- A61M5/31595—Pre-defined multi-dose administration by repeated overcoming of means blocking the free advancing movement of piston rod, e.g. by tearing or de-blocking
Landscapes
- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361907577P | 2013-11-22 | 2013-11-22 | |
| US61/907,577 | 2013-11-22 | ||
| EP14165750.2 | 2014-04-24 | ||
| EP14165750 | 2014-04-24 | ||
| PCT/EP2014/074706 WO2015074981A2 (en) | 2013-11-22 | 2014-11-17 | Drug delivery device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2016122123A true RU2016122123A (ru) | 2017-12-27 |
Family
ID=50542895
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2016122123A RU2016122123A (ru) | 2013-11-22 | 2014-11-17 | Устройство для доставки лекарственного средства |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US10525204B2 (enExample) |
| EP (1) | EP3071261B1 (enExample) |
| JP (1) | JP6479795B2 (enExample) |
| KR (1) | KR20160088881A (enExample) |
| CN (1) | CN105744974B (enExample) |
| AU (1) | AU2014352061A1 (enExample) |
| IL (1) | IL245007A0 (enExample) |
| MX (1) | MX2016006672A (enExample) |
| RU (1) | RU2016122123A (enExample) |
| WO (1) | WO2015074981A2 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL3399214T3 (pl) * | 2017-05-05 | 2021-01-25 | Eppendorf Ag | Elektroniczny napęd dozujący |
| JP6847792B2 (ja) * | 2017-09-05 | 2021-03-24 | 株式会社デンテック | エキスパンションスクリュー |
| WO2025083461A1 (en) * | 2023-10-17 | 2025-04-24 | Parvizi Fardin | Pen-type substance delivering device |
Family Cites Families (56)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US533575A (en) * | 1895-02-05 | wilkens | ||
| DE8804656U1 (de) * | 1988-04-08 | 1988-08-04 | Bader, Mohandes, 2350 Neumünster | Medizinische Spritze |
| US5127906A (en) * | 1989-04-28 | 1992-07-07 | Flp Enterprises, Inc. | Non-reusable syringe |
| US5226895A (en) * | 1989-06-05 | 1993-07-13 | Eli Lilly And Company | Multiple dose injection pen |
| GB9007113D0 (en) * | 1990-03-29 | 1990-05-30 | Sams Bernard | Dispensing device |
| DE59202070D1 (de) * | 1991-07-24 | 1995-06-08 | Medico Dev Investment Co | Injektor. |
| DK175491D0 (da) * | 1991-10-18 | 1991-10-18 | Novo Nordisk As | Apparat |
| US5279585A (en) * | 1992-02-04 | 1994-01-18 | Becton, Dickinson And Company | Medication delivery pen having improved dose delivery features |
| US5320609A (en) * | 1992-12-07 | 1994-06-14 | Habley Medical Technology Corporation | Automatic pharmaceutical dispensing syringe |
| US5383865A (en) * | 1993-03-15 | 1995-01-24 | Eli Lilly And Company | Medication dispensing device |
| ZA941881B (en) * | 1993-04-02 | 1995-09-18 | Lilly Co Eli | Manifold medication injection apparatus and method |
| US5582598A (en) * | 1994-09-19 | 1996-12-10 | Becton Dickinson And Company | Medication delivery pen with variable increment dose scale |
| NZ302558A (en) * | 1995-03-07 | 1999-11-29 | Lilly Co Eli | Dispensing apparatus with a medication cartridge with a manually adjustable metering mechanism |
| US5688251A (en) * | 1995-09-19 | 1997-11-18 | Becton Dickinson And Company | Cartridge loading and priming mechanism for a pen injector |
| US5674204A (en) * | 1995-09-19 | 1997-10-07 | Becton Dickinson And Company | Medication delivery pen cap actuated dose delivery clutch |
| US5648238A (en) | 1996-06-18 | 1997-07-15 | Incyte Pharmaceuticals, Inc. | Human protein kinase C inhibitor homolog |
| DE19730999C1 (de) * | 1997-07-18 | 1998-12-10 | Disetronic Licensing Ag | Dosierknopfsicherung an einer Vorrichtung zur dosierten Verabreichung eines injizierbaren Produkts |
| US5921966A (en) * | 1997-08-11 | 1999-07-13 | Becton Dickinson And Company | Medication delivery pen having an improved clutch assembly |
| KR100574630B1 (ko) | 1998-01-30 | 2006-04-27 | 노보 노르디스크 에이/에스 | 주입 주사기 |
| US6221053B1 (en) | 1998-02-20 | 2001-04-24 | Becton, Dickinson And Company | Multi-featured medication delivery pen |
| US5961495A (en) * | 1998-02-20 | 1999-10-05 | Becton, Dickinson And Company | Medication delivery pen having a priming mechanism |
| US6248095B1 (en) * | 1998-02-23 | 2001-06-19 | Becton, Dickinson And Company | Low-cost medication delivery pen |
| CA2378325C (en) | 1999-08-05 | 2008-09-30 | Becton, Dickinson And Company | Medication delivery pen |
| GB0007071D0 (en) * | 2000-03-24 | 2000-05-17 | Sams Bernard | One-way clutch mechanisms and injector devices |
| US6663602B2 (en) * | 2000-06-16 | 2003-12-16 | Novo Nordisk A/S | Injection device |
| US6899699B2 (en) * | 2001-01-05 | 2005-05-31 | Novo Nordisk A/S | Automatic injection device with reset feature |
| JP4283545B2 (ja) * | 2001-05-16 | 2009-06-24 | イーライ リリー アンド カンパニー | リセット簡易化式駆動アセンブリー付きの薬物注射装置 |
| GB0304823D0 (en) | 2003-03-03 | 2003-04-09 | Dca Internat Ltd | Improvements in and relating to a pen-type injector |
| GB0304822D0 (en) | 2003-03-03 | 2003-04-09 | Dca Internat Ltd | Improvements in and relating to a pen-type injector |
| SI1656170T1 (sl) * | 2003-08-12 | 2019-05-31 | Eli Lilly And Company | Oprema za izdajanje zdravil s trojnim vijačnim navojem za mehanski pospešek |
| DE102004063645A1 (de) * | 2004-12-31 | 2006-07-20 | Tecpharma Licensing Ag | Vorrichtung zur dosierten Verabreichung eines fluiden Produkts mit Entkopplung für einen Behältniswechsel |
| US8992484B2 (en) * | 2008-01-23 | 2015-03-31 | Novo Nordisk A/S | Device for injecting apportioned doses of liquid drug |
| US8647309B2 (en) * | 2008-05-02 | 2014-02-11 | Sanofi-Aventis Deutschland Gmbh | Medication delivery device |
| US8475414B2 (en) * | 2008-12-02 | 2013-07-02 | Sanofi-Aventis Deutschland Gmbh | Medication delivery device and method for operating a medication delivery device |
| EP2196233A1 (en) * | 2008-12-12 | 2010-06-16 | Sanofi-Aventis Deutschland GmbH | Resettable drive mechanism for a medication delivery device and medication delivery device |
| DE102009003721A1 (de) * | 2009-04-01 | 2010-10-07 | Medimatik Gmbh | Applikationsgerät |
| US9402960B2 (en) * | 2009-09-30 | 2016-08-02 | Sanofi-Aventis Deutschland Gmbh | Drive mechanism for a drug delivery device and use of a reset member for a drive mechanism |
| US10010678B2 (en) * | 2010-03-31 | 2018-07-03 | Emperra Gmbh E-Health Technologies | Assembly to administer insulin from a cartridge |
| US8986259B2 (en) * | 2010-03-31 | 2015-03-24 | Sanofi-Aventis Deutschland Gmbh | Piston rod assembly for a drug delivery device |
| EP2438944A1 (en) * | 2010-10-08 | 2012-04-11 | Sanofi-Aventis Deutschland GmbH | Auto-injector |
| EP2452710A1 (en) * | 2010-11-12 | 2012-05-16 | Sanofi-Aventis Deutschland GmbH | Assembly for a drug delivery device and piston rod |
| US20160287802A1 (en) * | 2011-04-24 | 2016-10-06 | Sanofi-Aventis Deutschland Gmbh | Drug delivery device with dose delivery clicker |
| CA2833744A1 (en) * | 2011-05-13 | 2012-11-22 | Sanofi-Aventis Deutschland Gmbh | An assembly for a drug delivery device |
| CN104203316A (zh) * | 2012-04-19 | 2014-12-10 | 赛诺菲-安万特德国有限公司 | 用于药物输送装置的组件和药物输送装置 |
| CN104955506B (zh) * | 2013-02-04 | 2018-09-14 | 赛诺菲-安万特德国有限公司 | 用于药物输送装置的组件 |
| TW201507749A (zh) * | 2013-03-11 | 2015-03-01 | Sanofi Aventis Deutschland | 用於藥物輸送裝置之組件 |
| EP3035985A1 (en) * | 2013-08-22 | 2016-06-29 | Sanofi-Aventis Deutschland GmbH | Assembly for a drug delivery device and use of an attenuation member |
| JP2016529008A (ja) * | 2013-08-28 | 2016-09-23 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | 薬物送達デバイスのためのアセンブリ |
| JP6518246B2 (ja) * | 2013-11-22 | 2019-05-22 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | ばね支援薬物送達デバイス |
| WO2015074984A1 (en) * | 2013-11-22 | 2015-05-28 | Sanofi-Aventis Deutschland Gmbh | Drug delivery device with dose knob clutch |
| JP6815198B2 (ja) * | 2013-11-22 | 2021-01-20 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | 一方向カップリングを有する薬物送達デバイス |
| JP6566946B2 (ja) * | 2013-11-22 | 2019-08-28 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | 偽造防止機能を有する薬物送達デバイス |
| EP3071268B1 (en) * | 2013-11-22 | 2019-04-03 | Sanofi-Aventis Deutschland GmbH | Assembly for a drug delivery device |
| EP3071265B1 (en) * | 2013-11-22 | 2023-04-26 | Sanofi-Aventis Deutschland GmbH | Spring assisted drug delivery device |
| EP3082910B1 (en) * | 2013-12-20 | 2020-03-04 | Sanofi-Aventis Deutschland GmbH | Assembly for a drug delivery device and drug delivery device |
| EP2891503A1 (en) * | 2014-01-02 | 2015-07-08 | Sanofi-Aventis Deutschland GmbH | Assembly for a drug delivery device |
-
2014
- 2014-11-17 AU AU2014352061A patent/AU2014352061A1/en not_active Abandoned
- 2014-11-17 EP EP14799435.4A patent/EP3071261B1/en active Active
- 2014-11-17 MX MX2016006672A patent/MX2016006672A/es unknown
- 2014-11-17 RU RU2016122123A patent/RU2016122123A/ru unknown
- 2014-11-17 US US15/037,338 patent/US10525204B2/en active Active
- 2014-11-17 WO PCT/EP2014/074706 patent/WO2015074981A2/en not_active Ceased
- 2014-11-17 JP JP2016530904A patent/JP6479795B2/ja active Active
- 2014-11-17 CN CN201480063666.XA patent/CN105744974B/zh active Active
- 2014-11-17 KR KR1020167014618A patent/KR20160088881A/ko not_active Withdrawn
-
2016
- 2016-04-10 IL IL245007A patent/IL245007A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP3071261A2 (en) | 2016-09-28 |
| AU2014352061A1 (en) | 2016-05-19 |
| EP3071261B1 (en) | 2019-05-08 |
| MX2016006672A (es) | 2016-09-06 |
| CN105744974A (zh) | 2016-07-06 |
| CN105744974B (zh) | 2019-12-10 |
| WO2015074981A3 (en) | 2015-11-19 |
| IL245007A0 (en) | 2016-05-31 |
| WO2015074981A2 (en) | 2015-05-28 |
| JP6479795B2 (ja) | 2019-03-06 |
| KR20160088881A (ko) | 2016-07-26 |
| US20160296709A1 (en) | 2016-10-13 |
| US10525204B2 (en) | 2020-01-07 |
| JP2016537094A (ja) | 2016-12-01 |
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