RU2016118802A - Наносимый распылением перевязочный материал для ожогов - Google Patents

Наносимый распылением перевязочный материал для ожогов Download PDF

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RU2016118802A
RU2016118802A RU2016118802A RU2016118802A RU2016118802A RU 2016118802 A RU2016118802 A RU 2016118802A RU 2016118802 A RU2016118802 A RU 2016118802A RU 2016118802 A RU2016118802 A RU 2016118802A RU 2016118802 A RU2016118802 A RU 2016118802A
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Prior art keywords
dressing
approximately
copolymer
burn
microparticles
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RU2016118802A
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English (en)
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RU2016118802A3 (ru
Inventor
Карл Джей ФРИР
Джозеф Мэтью МАРТЕН
Стефен Джон КЭРРОЛЛ
Жи-лонг ШИ
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Адвансд Фёрст Аид Рисёрч Пте. Лтд.
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Publication of RU2016118802A publication Critical patent/RU2016118802A/ru
Publication of RU2016118802A3 publication Critical patent/RU2016118802A3/ru

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061Use of materials characterised by their function or physical properties
    • A61L26/0076Sprayable compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/727Heparin; Heparan
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/08Oxides; Hydroxides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/12Aerosols; Foams
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0004Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing inorganic materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0014Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0023Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061Use of materials characterised by their function or physical properties
    • A61L26/0066Medicaments; Biocides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/23Carbohydrates
    • A61L2300/236Glycosaminoglycans, e.g. heparin, hyaluronic acid, chondroitin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00Materials characterised by their function or physical properties
    • A61L2400/12Nanosized materials, e.g. nanofibres, nanoparticles, nanowires, nanotubes; Nanostructured surfaces

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thermotherapy And Cooling Therapy Devices (AREA)

Claims (10)

1. Наносимый распылением перевязочный материал для ожогов, содержащий пленкообразующий полимер и частицы оксида алюминия.
2. Перевязочный материал по п. 1, дополнительно содержащий растворитель.
3. Перевязочный материал по п. 2, дополнительно содержащий гепарансульфат.
4. Перевязочный материал по п. 1, в котором указанным пленкообразующим полимером является сополимер метилвинилового эфира и малеиновой кислоты, при этом частицы указанного оксида алюминия имеют диаметры от приблизительно 5 до приблизительно 100 нанометров, и дополнительно содержатся изопропанол и вода.
5. Способ лечения ожога, предусматривающий применение теплопроводной композиции по отношению к ожогу, при этом указанная композиция содержит пленкообразующий полимер с частицами оксида алюминия.
6. Способ по п. 5, при котором композицию применяют посредством аэрозольного распылителя.
7. Композиция перевязочного материала для ожогов, содержащая от приблизительно 1% до приблизительно 20% сополимера метилвинилового эфира и малеиновой кислоты, от приблизительно 10% до приблизительно 90% изопропанола, от приблизительно 10% до приблизительно 40% воды и от приблизительно 10% до приблизительно 30% микрочастиц оксида алюминия.
8. Перевязочный материал для ожогов по п. 7, содержащих приблизительно 2% сополимера метилвинилового эфира и малеиновой кислоты, приблизительно 50% изопропанола, приблизительно 28% воды и приблизительно 20% микрочастиц оксида алюминия.
9. Перевязочный материал для ожогов по п. 8, в котором указанные микрочастицы оксида алюминия имеют средний размер приблизительно 10 микрометров.
10. Способ заживления обожженной кожи, при этом способ предусматривает применение перевязочного материала по отношению к обожженной коже, при этом перевязочный материал получают по любому из пп. 1-9, и улучшение рассеивания тепла от обожженной кожи.
RU2016118802A 2013-10-21 2014-10-20 Наносимый распылением перевязочный материал для ожогов RU2016118802A (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361893355P 2013-10-21 2013-10-21
US61/893,355 2013-10-21
PCT/SG2014/000494 WO2015060786A1 (en) 2013-10-21 2014-10-20 Spray-on burn dressing

Publications (2)

Publication Number Publication Date
RU2016118802A true RU2016118802A (ru) 2017-11-28
RU2016118802A3 RU2016118802A3 (ru) 2018-07-18

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Family Applications (1)

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RU2016118802A RU2016118802A (ru) 2013-10-21 2014-10-20 Наносимый распылением перевязочный материал для ожогов

Country Status (11)

Country Link
US (1) US20160250378A1 (ru)
EP (1) EP3060267A4 (ru)
JP (1) JP2016533792A (ru)
KR (1) KR20160075673A (ru)
CN (2) CN105828845A (ru)
AU (2) AU2014337758B2 (ru)
MX (1) MX2016005211A (ru)
PH (2) PH12016500751A1 (ru)
RU (1) RU2016118802A (ru)
SG (1) SG11201603176WA (ru)
WO (1) WO2015060786A1 (ru)

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CN108785737A (zh) * 2018-06-20 2018-11-13 北京点域科技有限公司 一种医用伤口快封液的制备方法
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Publication number Publication date
EP3060267A4 (en) 2017-05-31
PH12017500908A1 (en) 2017-11-27
JP2016533792A (ja) 2016-11-04
WO2015060786A1 (en) 2015-04-30
EP3060267A1 (en) 2016-08-31
AU2015337128A1 (en) 2017-06-08
CN105828845A (zh) 2016-08-03
AU2014337758B2 (en) 2018-01-18
SG11201603176WA (en) 2016-05-30
KR20160075673A (ko) 2016-06-29
CN107106726A (zh) 2017-08-29
RU2016118802A3 (ru) 2018-07-18
PH12016500751A1 (en) 2016-06-13
US20160250378A1 (en) 2016-09-01
MX2016005211A (es) 2016-08-08

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