RU2015137615A3 - - Google Patents
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- RU2015137615A3 RU2015137615A3 RU2015137615A RU2015137615A RU2015137615A3 RU 2015137615 A3 RU2015137615 A3 RU 2015137615A3 RU 2015137615 A RU2015137615 A RU 2015137615A RU 2015137615 A RU2015137615 A RU 2015137615A RU 2015137615 A3 RU2015137615 A3 RU 2015137615A3
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361786288P | 2013-03-14 | 2013-03-14 | |
| US61/786,288 | 2013-03-14 | ||
| PCT/US2014/021426 WO2014158998A1 (en) | 2013-03-14 | 2014-03-06 | Substituted pyridine and pyrazine compounds as pde4 inhibitors |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2018130876A Division RU2802185C2 (ru) | 2013-03-14 | 2014-03-06 | Замещенные пиридиновые и пиразиновые соединения в качестве ингибиторов pde4 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| RU2015137615A RU2015137615A (ru) | 2017-04-19 |
| RU2015137615A3 true RU2015137615A3 (enExample) | 2018-01-29 |
| RU2668073C2 RU2668073C2 (ru) | 2018-09-26 |
Family
ID=51530139
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2015137615A RU2668073C2 (ru) | 2013-03-14 | 2014-03-06 | Замещенные пиридиновые и пиразиновые соединения в качестве ингибиторов pde4 |
Country Status (17)
| Country | Link |
|---|---|
| US (8) | US20160009691A1 (enExample) |
| EP (2) | EP2970212B1 (enExample) |
| JP (2) | JP6282721B2 (enExample) |
| KR (1) | KR102232221B1 (enExample) |
| CN (2) | CN105143207B (enExample) |
| AU (2) | AU2014241430B2 (enExample) |
| BR (1) | BR112015022474B1 (enExample) |
| CA (1) | CA2895209C (enExample) |
| DK (1) | DK3345902T3 (enExample) |
| ES (1) | ES2769181T3 (enExample) |
| IL (1) | IL240804B (enExample) |
| MX (1) | MX370188B (enExample) |
| NZ (1) | NZ711587A (enExample) |
| RU (1) | RU2668073C2 (enExample) |
| SG (2) | SG11201504709PA (enExample) |
| TW (2) | TWI623523B (enExample) |
| WO (1) | WO2014158998A1 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2014241430B2 (en) * | 2013-03-14 | 2018-04-26 | Dart Neuroscience (Cayman) Ltd. | Substituted pyridine and pyrazine compounds as PDE4 inhibitors |
| EP3519816A4 (en) * | 2016-09-29 | 2020-05-06 | The Regents of the University of California | CONNECTIONS FOR INCREASING NEURONAL PLASTICITY |
| CA3135420A1 (en) * | 2018-04-05 | 2019-10-10 | Universiteit Hasselt | Selective pde4d inhibitors against demyelinating diseases |
| CN109438434B (zh) * | 2018-11-19 | 2021-05-04 | 华南农业大学 | 一种含噁唑环的2-氰基亚氨基噻唑烷类化合物及其制备方法和应用 |
| WO2020176597A1 (en) | 2019-02-27 | 2020-09-03 | The Regents Of The University Of California | N-substituted indoles and other heterocycles for treating brain disorders |
| KR102946120B1 (ko) | 2019-02-27 | 2026-03-30 | 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 | 뇌 장애를 치료하기 위한 아제피노-인돌 및 다른 헤테로사이클 |
| JP2022531129A (ja) * | 2019-04-23 | 2022-07-06 | テトラ ディスカバリー パートナーズ インコーポレイテッド | Ｐｄｅ４ｄ阻害剤としての３－ヒドロキシ－２－フェニル－６－（ピラゾール－４－イルメチル）ピリジン誘導体 |
| WO2020227312A1 (en) * | 2019-05-06 | 2020-11-12 | Calcimedica, Inc. | Synthesis of crac channel inhibitors |
| HRP20220797T1 (hr) * | 2019-11-07 | 2022-10-14 | Small Pharma Ltd | Spojevi |
| EP4192828A1 (en) | 2020-08-04 | 2023-06-14 | Nura Bio, Inc. | Substituted pyridine derivatives as sarm1 inhibitors |
| CN111995585B (zh) * | 2020-08-04 | 2022-01-25 | 常州大学 | 嘧啶乙酰胺类化合物及其作为磷酸二酯酶pde2活性抑制剂的应用 |
| WO2022060812A1 (en) | 2020-09-16 | 2022-03-24 | Nura Bio, Inc. | Substituted pyridine derivatives as sarm1 inhibitors |
| JP7791898B2 (ja) | 2020-11-13 | 2025-12-24 | カルシメディカ，インク． | Ｃｒａｃチャネル阻害剤の合成の改善 |
| WO2022221415A2 (en) | 2021-04-13 | 2022-10-20 | The Regents Of The University Of California | Tetracyclic compounds for treating brain disorders |
| KR20240041987A (ko) | 2021-07-28 | 2024-04-01 | 누라 바이오, 인크. | Sarm1 억제제로서 치환된 피리딘 유도체 |
| JP2025502615A (ja) | 2021-12-15 | 2025-01-28 | デリックス セラピューティクス，インク． | フェノキシおよびベンジルオキシ置換サイコプラストゲンならびにその使用 |
| CN116265440B (zh) * | 2021-12-16 | 2024-09-27 | 贵州大学 | 一种水杨酮拼接吡啶酮类化合物及其制备方法及应用 |
| EP4562001A4 (en) * | 2022-07-27 | 2026-08-19 | Nura Bio Inc | Substituted pyridine derivatives as sarm1 inhibitors |
| EP4596554A4 (en) | 2022-09-29 | 2025-12-10 | Suzhou Arkbiopharmaceutical Co Ltd | Fused AZA Cyclic Compound, its Preparation Process and its Use in Medicine |
| CN116082254B (zh) * | 2022-12-28 | 2025-04-11 | 浙江永太科技股份有限公司 | 一种1-烷基-1,2,4-三氮唑-3-甲醇的制备方法 |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4938949A (en) | 1988-09-12 | 1990-07-03 | University Of New York | Treatment of damaged bone marrow and dosage units therefor |
| AU1504599A (en) | 1997-12-17 | 1999-07-05 | Shionogi & Co., Ltd. | Novel pyridine compounds |
| US7868015B2 (en) | 2000-08-10 | 2011-01-11 | Cold Spring Harbor Laboratory | Phosphodiesesterase 4 inhibitors for the treatment of a cognitive deficit |
| US7947731B2 (en) | 2000-08-10 | 2011-05-24 | Cold Spring Harbor Laboratory | Augmented cognitive training |
| US9931318B2 (en) | 2003-04-08 | 2018-04-03 | Dart Neuroscience (Cayman) Ltd. | Phosphodiesterase 4 inhibitors for cognitive and motor rehabilitation |
| GB0111078D0 (en) | 2001-05-04 | 2001-06-27 | Novartis Ag | Organic compounds |
| AR037517A1 (es) | 2001-11-05 | 2004-11-17 | Novartis Ag | Derivados de naftiridinas, un proceso para su preparacion, composicion farmaceutica y el uso de los mismos para la preparacion de un medicamento para el tratamiento de una enfermedad inflamatoria |
| TW200304375A (en) | 2001-12-06 | 2003-10-01 | Maxia Pharmaceuticals Inc | 2-Substituted thiazolidinone and oxazolidinone derivatives for the inhibition of phosphatases and the treatment of cancer |
| RU2356893C2 (ru) | 2002-11-19 | 2009-05-27 | Мемори Фармасьютиклз Корпорейшн | Ингибиторы фосфодиэстеразы 4 |
| GB0229281D0 (en) | 2002-12-16 | 2003-01-22 | Novartis Ag | Organic compounds |
| US20050020587A1 (en) | 2003-07-25 | 2005-01-27 | Pfizer Inc | Nicotinamide derivatives useful as PDE4 inhibitors |
| MY141255A (en) * | 2003-12-11 | 2010-03-31 | Memory Pharm Corp | Phosphodiesterase 4 inhibitors, including n-substituted diarylamine analogs |
| KR101267392B1 (ko) * | 2004-06-30 | 2013-05-23 | 주식회사 씨앤드씨신약연구소 | 피리딘 유도체 및 그의 제조방법 |
| GB0425572D0 (en) | 2004-11-19 | 2004-12-22 | Glaxo Group Ltd | 1,7-Naphthyridines |
| WO2006124874A2 (en) * | 2005-05-12 | 2006-11-23 | Kalypsys, Inc. | Inhibitors of b-raf kinase |
| US7829713B2 (en) | 2006-02-28 | 2010-11-09 | Helicon Therapeutics, Inc. | Therapeutic piperazines |
| EP2465850B1 (en) | 2006-02-28 | 2016-11-23 | Dart Neuroscience (Cayman) Ltd | Therapeutic compounds |
| HRP20090395T1 (hr) | 2006-04-19 | 2009-08-31 | Boehringer Ingelheim International Gmbh | Dihidrotienpirimidini za liječenje upalnih bolesti |
| WO2007123953A2 (en) * | 2006-04-19 | 2007-11-01 | Memory Pharmaceuticals Corporation | Phosphodiesterase 4 inhibitors |
| WO2007135026A2 (de) | 2006-05-24 | 2007-11-29 | Boehringer Ingelheim International Gmbh | Substituierte pteridine als therapeutika |
| EP2074096B1 (en) * | 2006-10-04 | 2012-06-27 | F. Hoffmann-La Roche AG | 3-pyridinecarboxamide and 2-pyrazinecarboxamide derivatives as hdl-cholesterol raising agents |
| AU2008254907A1 (en) | 2007-05-15 | 2008-11-27 | Helicon Therapeutics, Inc. | Methods of identifying genes involved in memory formation using small interfering RNA(siRNA) |
| US8222243B2 (en) | 2007-08-27 | 2012-07-17 | Dart Neuroscience (Cayman) Ltd | Therapeutic isoxazole compounds |
| JP5529746B2 (ja) | 2007-11-21 | 2014-06-25 | デコード ジェネティクス イーエイチエフ | 炎症性疾患、心臓血管疾患及び中枢神経系障害を治療するための置換されたベンゾアゾールｐｄｅ４阻害剤 |
| WO2009067597A1 (en) | 2007-11-21 | 2009-05-28 | Decode Genetics Ehf | 4- (or 5-) substituted catechol derivatives |
| CN103351390A (zh) * | 2007-11-21 | 2013-10-16 | 解码遗传Ehf公司 | 用于治疗肺部和心血管病症的联芳基pde4 抑制剂 |
| EP2222638A2 (en) * | 2007-11-21 | 2010-09-01 | Decode Genetics EHF | Biaryl pde4 inhibitors for treating inflammation |
| WO2010003084A2 (en) | 2008-07-02 | 2010-01-07 | Memory Pharmaceuticals Corporation | Phosphodiesterase 4 inhibitors |
| WO2010056195A1 (en) | 2008-11-14 | 2010-05-20 | Astrazeneca Ab | New compounds 575 |
| WO2010059836A1 (en) | 2008-11-20 | 2010-05-27 | Decode Genetics Ehf | Substituted aza-bridged bicyclics for cardiovascular and cns disease |
| JP2013540145A (ja) * | 2010-10-21 | 2013-10-31 | ウニベルシテート デス ザールランデス | コルチゾール依存性疾患の治療用の選択的ｃｙｐ１１ｂ１阻害剤 |
| AU2014241430B2 (en) * | 2013-03-14 | 2018-04-26 | Dart Neuroscience (Cayman) Ltd. | Substituted pyridine and pyrazine compounds as PDE4 inhibitors |
-
2014
- 2014-03-06 AU AU2014241430A patent/AU2014241430B2/en active Active
- 2014-03-06 KR KR1020157029168A patent/KR102232221B1/ko active Active
- 2014-03-06 CN CN201480022741.8A patent/CN105143207B/zh active Active
- 2014-03-06 US US14/770,759 patent/US20160009691A1/en not_active Abandoned
- 2014-03-06 EP EP14776154.8A patent/EP2970212B1/en active Active
- 2014-03-06 EP EP18155385.0A patent/EP3345902B1/en active Active
- 2014-03-06 JP JP2016500760A patent/JP6282721B2/ja active Active
- 2014-03-06 WO PCT/US2014/021426 patent/WO2014158998A1/en not_active Ceased
- 2014-03-06 BR BR112015022474-1A patent/BR112015022474B1/pt active IP Right Grant
- 2014-03-06 MX MX2015011140A patent/MX370188B/es active IP Right Grant
- 2014-03-06 CN CN201810235079.4A patent/CN108299400B/zh active Active
- 2014-03-06 SG SG11201504709PA patent/SG11201504709PA/en unknown
- 2014-03-06 CA CA2895209A patent/CA2895209C/en active Active
- 2014-03-06 RU RU2015137615A patent/RU2668073C2/ru active
- 2014-03-06 ES ES18155385T patent/ES2769181T3/es active Active
- 2014-03-06 NZ NZ711587A patent/NZ711587A/en unknown
- 2014-03-06 SG SG10201703405PA patent/SG10201703405PA/en unknown
- 2014-03-06 DK DK18155385T patent/DK3345902T3/da active
- 2014-03-11 US US14/204,934 patent/US9120770B2/en active Active
- 2014-03-11 US US14/205,033 patent/US9040692B2/en active Active
- 2014-03-14 TW TW103109304A patent/TWI623523B/zh active
- 2014-03-14 TW TW107111344A patent/TWI672292B/zh active
-
2015
- 2015-05-22 US US14/720,321 patent/US9573937B2/en active Active
- 2015-08-25 IL IL24080415A patent/IL240804B/en active IP Right Grant
-
2018
- 2018-01-24 JP JP2018009464A patent/JP6505878B2/ja active Active
- 2018-03-26 AU AU2018202148A patent/AU2018202148B2/en active Active
- 2018-06-06 US US16/001,883 patent/US20180346448A1/en not_active Abandoned
-
2019
- 2019-05-28 US US16/424,366 patent/US11279691B2/en active Active
-
2022
- 2022-03-15 US US17/695,252 patent/US20230075774A1/en not_active Abandoned
-
2024
- 2024-05-10 US US18/661,369 patent/US20250122172A1/en active Pending
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