RU2015106742A - Композиции, содержащие химерные молекулы ospa и способы их применения - Google Patents

Композиции, содержащие химерные молекулы ospa и способы их применения Download PDF

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Publication number
RU2015106742A
RU2015106742A RU2015106742A RU2015106742A RU2015106742A RU 2015106742 A RU2015106742 A RU 2015106742A RU 2015106742 A RU2015106742 A RU 2015106742A RU 2015106742 A RU2015106742 A RU 2015106742A RU 2015106742 A RU2015106742 A RU 2015106742A
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RU
Russia
Prior art keywords
borrelia
composition
composition according
bacteria
standard dose
Prior art date
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RU2015106742A
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English (en)
Russian (ru)
Inventor
Ноэль П. БАРРЕТТ
Геральд АЙХИНГЕР
Брайан А. КРОУ
Иан ЛИВИ
Нина Вресснигг
Original Assignee
Бакстер Интернэшнл Инк.
Бакстер Хелткэр Са
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Application filed by Бакстер Интернэшнл Инк., Бакстер Хелткэр Са filed Critical Бакстер Интернэшнл Инк.
Publication of RU2015106742A publication Critical patent/RU2015106742A/ru

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/0225—Spirochetes, e.g. Treponema, Leptospira, Borrelia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Gram-negative bacteria
    • C07K16/1207—Gram-negative bacteria from Spirochaetales (O), e.g. Treponema, Leptospira
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/58—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
RU2015106742A 2012-07-27 2013-07-11 Композиции, содержащие химерные молекулы ospa и способы их применения RU2015106742A (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261676668P 2012-07-27 2012-07-27
US61/676,668 2012-07-27
PCT/US2013/050058 WO2014018274A1 (en) 2012-07-27 2013-07-11 Compositions comprising chimeric ospa molecules and methods of use thereof

Publications (1)

Publication Number Publication Date
RU2015106742A true RU2015106742A (ru) 2016-09-20

Family

ID=48901170

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2015106742A RU2015106742A (ru) 2012-07-27 2013-07-11 Композиции, содержащие химерные молекулы ospa и способы их применения

Country Status (11)

Country Link
US (1) US9023367B2 (https=)
EP (2) EP2877206B1 (https=)
JP (1) JP2015524802A (https=)
KR (2) KR20200068756A (https=)
CN (1) CN104640563A (https=)
AU (3) AU2013293448A1 (https=)
CA (1) CA2879689A1 (https=)
PL (1) PL2877206T3 (https=)
RU (1) RU2015106742A (https=)
SI (1) SI2877206T1 (https=)
WO (1) WO2014018274A1 (https=)

Families Citing this family (8)

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Publication number Priority date Publication date Assignee Title
AU2011252844B2 (en) * 2010-05-14 2014-07-03 Baxalta GmbH Chimeric OspA genes, proteins, and methods of use thereof
JP6405103B2 (ja) * 2014-03-18 2018-10-17 日本製粉株式会社 ソバアレルゲン特異的モノクローナル抗体
CZ2014320A3 (cs) * 2014-05-09 2015-11-18 VÝZKUMNÝ ÚSTAV VETERINÁRNÍHO LÉKAŘSTVÍ, v.v.i. Polyepitopový antigen, vakcinační konstrukt a vakcína pro prevenci lymeské boreliózy
CN106771250B (zh) * 2017-01-06 2018-08-21 杭州京北生物科技有限公司 一种用于检测哺乳动物莱姆病的荧光素酶免疫共沉淀试剂盒
EP4132950A1 (en) * 2020-04-09 2023-02-15 Valneva Austria GmbH Compositions comprising three ospa fusion proteins for medical use
CN119173446A (zh) 2022-03-08 2024-12-20 赤盾医疗有限公司 机器人药物制备系统中的流体转移站
WO2025015042A1 (en) 2023-07-10 2025-01-16 Dynavax Technologies Corporation Lyme disease vaccines comprising an adjuvant and a borrelia outer surface protein a antigen
WO2025015077A1 (en) 2023-07-10 2025-01-16 Dynavax Technologies Corporation Lyme disease vaccines comprising an adjuvant and borrelia outer surface protein a and c antigens

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Also Published As

Publication number Publication date
CA2879689A1 (en) 2014-01-30
US20140030284A1 (en) 2014-01-30
AU2018203336B2 (en) 2019-10-31
JP2015524802A (ja) 2015-08-27
CN104640563A (zh) 2015-05-20
AU2020200708A1 (en) 2020-02-20
EP3682897A1 (en) 2020-07-22
AU2018203336A1 (en) 2018-05-31
PL2877206T3 (pl) 2020-12-14
WO2014018274A1 (en) 2014-01-30
US9023367B2 (en) 2015-05-05
HK1208627A1 (en) 2016-03-11
EP2877206A1 (en) 2015-06-03
SI2877206T1 (sl) 2020-07-31
EP2877206B1 (en) 2019-11-27
KR20150038380A (ko) 2015-04-08
KR20200068756A (ko) 2020-06-15
WO2014018274A8 (en) 2015-03-12
AU2013293448A1 (en) 2015-02-05

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