RU2015102002A - Композиции для лечения утомляемости, связанной с раковым заболеванием - Google Patents

Композиции для лечения утомляемости, связанной с раковым заболеванием Download PDF

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RU2015102002A
RU2015102002A RU2015102002A RU2015102002A RU2015102002A RU 2015102002 A RU2015102002 A RU 2015102002A RU 2015102002 A RU2015102002 A RU 2015102002A RU 2015102002 A RU2015102002 A RU 2015102002A RU 2015102002 A RU2015102002 A RU 2015102002A
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extract
ginsenoside
echinacea angustifolia
zingiber officinale
compositions
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RU2015102002A
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RU2631612C2 (ru
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Эцио БОМБАРДЕЛЛИ
Фабрицио КОРТИ
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Индена С.П.А.
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9068Zingiber, e.g. garden ginger
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/683Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2813Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00Preparations for use in therapy

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

1. Композиции, содержащие:а) экстракт женьшеня обыкновенного (Panax ginseng СА Mayer),б) экстракт имбиря аптечного (Zingiber officinale),в) экстракт эхинацеи узколистной (Echinacea angustifolia) иг) фосфолипидный комплекс силибина с фосфолипидамив качестве активных ингредиентов, в смеси с подходящими эксципиентами.2. Композиции по п. 1, где экстракты Zingiber officinale и Echinacea angustifolia представляют собой липофильные экстракты.3. Композиции по п. 1, где экстракт женьшеня имеет содержание гинзенозида 8% с отношением гинзенозид Rg1/гинзенозид Rb1, составляющим 0,5/1, экстракт Zingiber officinale имеет содержание гингерола 30%, и экстракт Echinacea angustifolia имеет содержание изобутиламида выше 20 мас.%.4. Композиции по п. 1 в форме таблеток, покрытых сахаром пилюль, мягких и твердых желатиновых капсул и целлюлозных капсул.5. Композиции по любому из пп. 1-4 для применения в лечении утомляемости, связанной с раковым заболеванием.

Claims (5)

1. Композиции, содержащие:
а) экстракт женьшеня обыкновенного (Panax ginseng СА Mayer),
б) экстракт имбиря аптечного (Zingiber officinale),
в) экстракт эхинацеи узколистной (Echinacea angustifolia) и
г) фосфолипидный комплекс силибина с фосфолипидами
в качестве активных ингредиентов, в смеси с подходящими эксципиентами.
2. Композиции по п. 1, где экстракты Zingiber officinale и Echinacea angustifolia представляют собой липофильные экстракты.
3. Композиции по п. 1, где экстракт женьшеня имеет содержание гинзенозида 8% с отношением гинзенозид Rg1/гинзенозид Rb1, составляющим 0,5/1, экстракт Zingiber officinale имеет содержание гингерола 30%, и экстракт Echinacea angustifolia имеет содержание изобутиламида выше 20 мас.%.
4. Композиции по п. 1 в форме таблеток, покрытых сахаром пилюль, мягких и твердых желатиновых капсул и целлюлозных капсул.
5. Композиции по любому из пп. 1-4 для применения в лечении утомляемости, связанной с раковым заболеванием.
RU2015102002A 2012-07-27 2013-07-11 Композиции для лечения утомляемости, связанной с раковым заболеванием RU2631612C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT001317A ITMI20121317A1 (it) 2012-07-27 2012-07-27 Composizioni per il trattamento della fatica oncologica
ITMI2012A001317 2012-07-27
PCT/EP2013/064711 WO2014016137A1 (en) 2012-07-27 2013-07-11 Compositions for treatment of cancer-related fatigue

Publications (2)

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RU2015102002A true RU2015102002A (ru) 2016-09-20
RU2631612C2 RU2631612C2 (ru) 2017-09-25

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RU2015102002A RU2631612C2 (ru) 2012-07-27 2013-07-11 Композиции для лечения утомляемости, связанной с раковым заболеванием

Country Status (22)

Country Link
US (1) US9566309B2 (ru)
EP (1) EP2877192B1 (ru)
JP (1) JP6129314B2 (ru)
KR (1) KR102091128B1 (ru)
CN (1) CN104540514B (ru)
AU (1) AU2013295227B2 (ru)
BR (1) BR112015001174B1 (ru)
CA (1) CA2879906A1 (ru)
DK (1) DK2877192T3 (ru)
ES (1) ES2590209T3 (ru)
HK (1) HK1209375A1 (ru)
HR (1) HRP20160774T1 (ru)
HU (1) HUE030002T2 (ru)
IL (1) IL236871B (ru)
IN (1) IN2015KN00222A (ru)
IT (1) ITMI20121317A1 (ru)
PL (1) PL2877192T3 (ru)
PT (1) PT2877192T (ru)
RU (1) RU2631612C2 (ru)
SG (1) SG11201500521XA (ru)
SI (1) SI2877192T1 (ru)
WO (1) WO2014016137A1 (ru)

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PL3040078T3 (pl) * 2013-08-30 2021-11-02 Green Cross Wellbeing Corporation Kompozycja do zapobiegania i leczenia zmęczenia związanego z nowotworem, zawierająca przetworzony proszek z żeń-szenia lub przetworzony ekstrakt z żeń-szenia o zwiększonej zawartości ginsenozydu
CA3005700A1 (en) * 2015-12-16 2017-06-22 Vivek Anand PARACHUR Tri-molecular complex of natural compounds
EP3335716A1 (en) * 2016-12-15 2018-06-20 Indena S.p.A. Process for the preparation of powder compositions
WO2022245923A1 (en) 2021-05-18 2022-11-24 Prostasis, Llc Compositions comprising mixtures of compounds and uses thereof

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IT1215291B (it) * 1985-07-17 1990-01-31 Inverni Della Beffa Spa Complessi di flavanolignani con fosfolipidi, loro preparazione e relative composizioni farmaceutiche.
EP0464298B1 (en) 1990-07-05 1995-06-21 INDENA S.p.A. Echinacea extracts, a process for the preparation thereof and formulations containing them
CZ292832B6 (cs) * 2001-08-30 2003-12-17 Ivax Pharmaceuticals S.R.O. Způsob přípravy silymarinu se zvýšenou rozpustností
US20030206978A1 (en) * 2001-11-29 2003-11-06 Bob Sherwood Agglomerated particles including an active agent coprocessed with silicified microcrystalline cellulose
EP1613206A2 (en) * 2003-04-16 2006-01-11 The University Of Mississippi Immunostimulatory agents in botanicals
US20050031710A1 (en) * 2003-08-08 2005-02-10 D'adamo Peter James Method of personal care and cosmetic product preparation and composition using human blood type
RU2277927C2 (ru) * 2004-09-15 2006-06-20 Наталья Ивановна Весельева Лечебно-профилактический комплекс "бальзам долголетие" общеукрепляющего и тонизирующего действия (варианты)
ITMI20090049A1 (it) * 2009-01-20 2010-07-21 Indena Spa Composizioni a base di estratti lipofili di zingiber officinale e di echinacea angustifolia per la prevenzione e il trattamento del riflusso gastro-esofageo e dell'emesi indotta da chemioterapici
CN101502320B (zh) * 2009-03-11 2012-09-05 王越 一种参姜红枣饮料冲剂的生产方法
IT1401141B1 (it) * 2010-07-26 2013-07-12 Indena Spa Formulazioni contenenti estratti di echinacea angustifolia e di zingiber officinale utili nella riduzione dell'infiammazione e del dolore periferico

Also Published As

Publication number Publication date
ITMI20121317A1 (it) 2014-01-28
US20150202246A1 (en) 2015-07-23
AU2013295227A1 (en) 2015-02-19
IN2015KN00222A (ru) 2015-06-12
EP2877192B1 (en) 2016-06-08
KR102091128B1 (ko) 2020-03-20
BR112015001174A2 (pt) 2017-06-27
JP2015522631A (ja) 2015-08-06
RU2631612C2 (ru) 2017-09-25
SI2877192T1 (sl) 2016-09-30
CN104540514A (zh) 2015-04-22
HUE030002T2 (en) 2017-04-28
PT2877192T (pt) 2016-09-13
CN104540514B (zh) 2020-03-27
SG11201500521XA (en) 2015-02-27
PL2877192T3 (pl) 2016-12-30
BR112015001174B1 (pt) 2021-02-02
HK1209375A1 (en) 2016-04-01
WO2014016137A1 (en) 2014-01-30
US9566309B2 (en) 2017-02-14
JP6129314B2 (ja) 2017-05-17
ES2590209T3 (es) 2016-11-18
DK2877192T3 (en) 2016-09-05
KR20150037890A (ko) 2015-04-08
EP2877192A1 (en) 2015-06-03
CA2879906A1 (en) 2014-01-30
AU2013295227B2 (en) 2017-04-27
IL236871B (en) 2018-01-31
HRP20160774T1 (hr) 2016-08-12

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