HRP20160774T1 - Pripravci za liječenje umora povezanog s karcinomom - Google Patents
Pripravci za liječenje umora povezanog s karcinomom Download PDFInfo
- Publication number
- HRP20160774T1 HRP20160774T1 HRP20160774TT HRP20160774T HRP20160774T1 HR P20160774 T1 HRP20160774 T1 HR P20160774T1 HR P20160774T T HRP20160774T T HR P20160774TT HR P20160774 T HRP20160774 T HR P20160774T HR P20160774 T1 HRP20160774 T1 HR P20160774T1
- Authority
- HR
- Croatia
- Prior art keywords
- extract
- ginsenoside
- cancer
- zingiber officinale
- treatment
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title claims 2
- 201000011510 cancer Diseases 0.000 title claims 2
- 239000000203 mixture Substances 0.000 title claims 2
- 239000000284 extract Substances 0.000 claims 5
- 238000002360 preparation method Methods 0.000 claims 4
- 244000273928 Zingiber officinale Species 0.000 claims 3
- 235000006886 Zingiber officinale Nutrition 0.000 claims 3
- 235000008397 ginger Nutrition 0.000 claims 3
- 239000001841 zingiber officinale Substances 0.000 claims 3
- 229940089161 ginsenoside Drugs 0.000 claims 2
- 229930182494 ginsenoside Natural products 0.000 claims 2
- 150000003904 phospholipids Chemical class 0.000 claims 2
- 244000133098 Echinacea angustifolia Species 0.000 claims 1
- UFNDONGOJKNAES-UHFFFAOYSA-N Ginsenoside Rb1 Natural products CC(=CCCC(C)(OC1OC(COC2OC(CO)C(O)C(O)C2O)C(O)C(O)C1O)C3CCC4(C)C3C(O)CC5C6(C)CCC(OC7OC(CO)C(O)C(O)C7OC8OC(CO)C(O)C(O)C8O)C(C)(C)C6CC(O)C45C)C UFNDONGOJKNAES-UHFFFAOYSA-N 0.000 claims 1
- 240000004371 Panax ginseng Species 0.000 claims 1
- 235000002789 Panax ginseng Nutrition 0.000 claims 1
- 239000013543 active substance Substances 0.000 claims 1
- 239000002775 capsule Substances 0.000 claims 1
- 229920002678 cellulose Polymers 0.000 claims 1
- 239000001913 cellulose Substances 0.000 claims 1
- 239000008298 dragée Substances 0.000 claims 1
- 235000014134 echinacea Nutrition 0.000 claims 1
- 229940064972 echinacea angustifolia extract Drugs 0.000 claims 1
- 235000020694 echinacea extract Nutrition 0.000 claims 1
- 239000007903 gelatin capsule Substances 0.000 claims 1
- NLDDIKRKFXEWBK-AWEZNQCLSA-N gingerol Chemical compound CCCCC[C@H](O)CC(=O)CCC1=CC=C(O)C(OC)=C1 NLDDIKRKFXEWBK-AWEZNQCLSA-N 0.000 claims 1
- JZLXEKNVCWMYHI-UHFFFAOYSA-N gingerol Natural products CCCCC(O)CC(=O)CCC1=CC=C(O)C(OC)=C1 JZLXEKNVCWMYHI-UHFFFAOYSA-N 0.000 claims 1
- 235000002780 gingerol Nutrition 0.000 claims 1
- 235000008434 ginseng Nutrition 0.000 claims 1
- 235000020710 ginseng extract Nutrition 0.000 claims 1
- GZYPWOGIYAIIPV-JBDTYSNRSA-N ginsenoside Rb1 Chemical compound C([C@H]1O[C@H]([C@@H]([C@@H](O)[C@@H]1O)O)O[C@@](C)(CCC=C(C)C)[C@@H]1[C@@H]2[C@@]([C@@]3(CC[C@H]4C(C)(C)[C@@H](O[C@H]5[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O5)O[C@H]5[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O5)O)CC[C@]4(C)[C@H]3C[C@H]2O)C)(C)CC1)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O GZYPWOGIYAIIPV-JBDTYSNRSA-N 0.000 claims 1
- TXEWRVNOAJOINC-UHFFFAOYSA-N ginsenoside Rb2 Natural products CC(=CCCC(OC1OC(COC2OCC(O)C(O)C2O)C(O)C(O)C1O)C3CCC4(C)C3C(O)CC5C6(C)CCC(OC7OC(CO)C(O)C(O)C7OC8OC(CO)C(O)C(O)C8O)C(C)(C)C6CCC45C)C TXEWRVNOAJOINC-UHFFFAOYSA-N 0.000 claims 1
- WFKAJVHLWXSISD-UHFFFAOYSA-N isobutyramide Chemical compound CC(C)C(N)=O WFKAJVHLWXSISD-UHFFFAOYSA-N 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9068—Zingiber, e.g. garden ginger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2813—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Inorganic Chemistry (AREA)
- Medicines Containing Plant Substances (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Claims (5)
1. Pripravci koji sadrže sljedeće:
(a) ekstrakt Panax ginseng CA Mayer,
(b) ekstrakt Zingiber officinale,
(c) ekstrakt Echinacea angustifolia te
(d) fosfolipidni kompleks silbina s fosfolipidima kao aktivnim tvarima, u smjesi s pogodnim ekscipijenioma.
2. Pripravci prema patentnom zahtjevu 1, naznačeni time da su ekstrakti Zingiber officinale i Echinacea angustifolia lipofilni ekstrakti.
3. Pripravci prema patentnom zahtjevu 1 ili 2, naznačeni time da je u ekstraktu ginsenga sadržaj ginsenozida 8%, a omjer ginsenozida Rgl/ginsenozida Rb1 jest 0.5/1, da je u ekstraktu Zingiber officinale sadržaj gingerola 30% te da je u ekstraktu Echinacea angustifolia sadržaj izobutilamida veći od 20% po masi.
4. Pripravci prema jednom ili više patentnih zahtjeva 1 do 3 u obliku tableta, pilula sa šećernom ovojnicom, mekih i tvrdih želatinskih kapsula ili celuloznih kapsula.
5. Pripravci prema patentnim zahtjevima 1-4 za upotrebu u liječenju umora povezanog s karcinomom.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT001317A ITMI20121317A1 (it) | 2012-07-27 | 2012-07-27 | Composizioni per il trattamento della fatica oncologica |
| EP13744458.4A EP2877192B1 (en) | 2012-07-27 | 2013-07-11 | Compositions for treatment of cancer-related fatigue |
| PCT/EP2013/064711 WO2014016137A1 (en) | 2012-07-27 | 2013-07-11 | Compositions for treatment of cancer-related fatigue |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20160774T1 true HRP20160774T1 (hr) | 2016-08-12 |
Family
ID=46939795
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20160774TT HRP20160774T1 (hr) | 2012-07-27 | 2016-07-01 | Pripravci za liječenje umora povezanog s karcinomom |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US9566309B2 (hr) |
| EP (1) | EP2877192B1 (hr) |
| JP (1) | JP6129314B2 (hr) |
| KR (1) | KR102091128B1 (hr) |
| CN (1) | CN104540514B (hr) |
| AU (1) | AU2013295227B2 (hr) |
| BR (1) | BR112015001174B1 (hr) |
| CA (1) | CA2879906A1 (hr) |
| DK (1) | DK2877192T3 (hr) |
| ES (1) | ES2590209T3 (hr) |
| HK (1) | HK1209375A1 (hr) |
| HR (1) | HRP20160774T1 (hr) |
| HU (1) | HUE030002T2 (hr) |
| IL (1) | IL236871B (hr) |
| IN (1) | IN2015KN00222A (hr) |
| IT (1) | ITMI20121317A1 (hr) |
| PL (1) | PL2877192T3 (hr) |
| PT (1) | PT2877192T (hr) |
| RU (1) | RU2631612C2 (hr) |
| SG (1) | SG11201500521XA (hr) |
| SI (1) | SI2877192T1 (hr) |
| WO (1) | WO2014016137A1 (hr) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015030283A1 (ko) | 2013-08-30 | 2015-03-05 | 주식회사 녹십자에이치에스 | 진세노사이드 성분이 증가된 가공인삼분말 또는 가공인삼추출물을 함유하는 암 관련 피로의 예방 및 치료용 조성물 |
| CN108366974A (zh) * | 2015-12-16 | 2018-08-03 | 维韦克·阿南德·帕拉库尔 | 天然化合物的三分子复合物 |
| EP3335716A1 (en) * | 2016-12-15 | 2018-06-20 | Indena S.p.A. | Process for the preparation of powder compositions |
| EP4340826A1 (en) | 2021-05-18 | 2024-03-27 | Prostasis, LLC | Compositions comprising mixtures of compounds and uses thereof |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1215291B (it) * | 1985-07-17 | 1990-01-31 | Inverni Della Beffa Spa | Complessi di flavanolignani con fosfolipidi, loro preparazione e relative composizioni farmaceutiche. |
| EP0464298B1 (en) | 1990-07-05 | 1995-06-21 | INDENA S.p.A. | Echinacea extracts, a process for the preparation thereof and formulations containing them |
| CZ292832B6 (cs) * | 2001-08-30 | 2003-12-17 | Ivax Pharmaceuticals S.R.O. | Způsob přípravy silymarinu se zvýšenou rozpustností |
| US20030206978A1 (en) * | 2001-11-29 | 2003-11-06 | Bob Sherwood | Agglomerated particles including an active agent coprocessed with silicified microcrystalline cellulose |
| AU2004231997A1 (en) * | 2003-04-16 | 2004-11-04 | The University Of Mississippi | Immunostimulatory agents in botanicals |
| US20050031710A1 (en) * | 2003-08-08 | 2005-02-10 | D'adamo Peter James | Method of personal care and cosmetic product preparation and composition using human blood type |
| RU2277927C2 (ru) * | 2004-09-15 | 2006-06-20 | Наталья Ивановна Весельева | Лечебно-профилактический комплекс "бальзам долголетие" общеукрепляющего и тонизирующего действия (варианты) |
| ITMI20090049A1 (it) * | 2009-01-20 | 2010-07-21 | Indena Spa | Composizioni a base di estratti lipofili di zingiber officinale e di echinacea angustifolia per la prevenzione e il trattamento del riflusso gastro-esofageo e dell'emesi indotta da chemioterapici |
| CN101502320B (zh) * | 2009-03-11 | 2012-09-05 | 王越 | 一种参姜红枣饮料冲剂的生产方法 |
| IT1401141B1 (it) * | 2010-07-26 | 2013-07-12 | Indena Spa | Formulazioni contenenti estratti di echinacea angustifolia e di zingiber officinale utili nella riduzione dell'infiammazione e del dolore periferico |
-
2012
- 2012-07-27 IT IT001317A patent/ITMI20121317A1/it unknown
-
2013
- 2013-07-11 CA CA2879906A patent/CA2879906A1/en not_active Abandoned
- 2013-07-11 BR BR112015001174-8A patent/BR112015001174B1/pt not_active IP Right Cessation
- 2013-07-11 DK DK13744458.4T patent/DK2877192T3/en active
- 2013-07-11 HU HUE13744458A patent/HUE030002T2/en unknown
- 2013-07-11 IN IN222KON2015 patent/IN2015KN00222A/en unknown
- 2013-07-11 PT PT137444584T patent/PT2877192T/pt unknown
- 2013-07-11 SG SG11201500521XA patent/SG11201500521XA/en unknown
- 2013-07-11 JP JP2015523483A patent/JP6129314B2/ja active Active
- 2013-07-11 SI SI201330255A patent/SI2877192T1/sl unknown
- 2013-07-11 AU AU2013295227A patent/AU2013295227B2/en not_active Ceased
- 2013-07-11 WO PCT/EP2013/064711 patent/WO2014016137A1/en active Application Filing
- 2013-07-11 CN CN201380039163.4A patent/CN104540514B/zh not_active Expired - Fee Related
- 2013-07-11 US US14/416,346 patent/US9566309B2/en active Active
- 2013-07-11 PL PL13744458.4T patent/PL2877192T3/pl unknown
- 2013-07-11 EP EP13744458.4A patent/EP2877192B1/en active Active
- 2013-07-11 ES ES13744458.4T patent/ES2590209T3/es active Active
- 2013-07-11 RU RU2015102002A patent/RU2631612C2/ru active
- 2013-07-11 KR KR1020157001976A patent/KR102091128B1/ko active IP Right Grant
-
2015
- 2015-01-22 IL IL236871A patent/IL236871B/en active IP Right Grant
- 2015-10-20 HK HK15110306.1A patent/HK1209375A1/xx unknown
-
2016
- 2016-07-01 HR HRP20160774TT patent/HRP20160774T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL236871B (en) | 2018-01-31 |
| DK2877192T3 (en) | 2016-09-05 |
| AU2013295227B2 (en) | 2017-04-27 |
| WO2014016137A1 (en) | 2014-01-30 |
| AU2013295227A1 (en) | 2015-02-19 |
| EP2877192A1 (en) | 2015-06-03 |
| CA2879906A1 (en) | 2014-01-30 |
| HK1209375A1 (en) | 2016-04-01 |
| EP2877192B1 (en) | 2016-06-08 |
| BR112015001174A2 (pt) | 2017-06-27 |
| ES2590209T3 (es) | 2016-11-18 |
| JP6129314B2 (ja) | 2017-05-17 |
| PL2877192T3 (pl) | 2016-12-30 |
| US9566309B2 (en) | 2017-02-14 |
| BR112015001174B1 (pt) | 2021-02-02 |
| CN104540514A (zh) | 2015-04-22 |
| CN104540514B (zh) | 2020-03-27 |
| JP2015522631A (ja) | 2015-08-06 |
| SI2877192T1 (sl) | 2016-09-30 |
| RU2631612C2 (ru) | 2017-09-25 |
| KR102091128B1 (ko) | 2020-03-20 |
| ITMI20121317A1 (it) | 2014-01-28 |
| IN2015KN00222A (hr) | 2015-06-12 |
| KR20150037890A (ko) | 2015-04-08 |
| SG11201500521XA (en) | 2015-02-27 |
| RU2015102002A (ru) | 2016-09-20 |
| HUE030002T2 (en) | 2017-04-28 |
| PT2877192T (pt) | 2016-09-13 |
| US20150202246A1 (en) | 2015-07-23 |
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