RU2013139860A - Способ анализа микрочипа и устройство считывания микрочипа - Google Patents

Способ анализа микрочипа и устройство считывания микрочипа Download PDF

Info

Publication number
RU2013139860A
RU2013139860A RU2013139860/28A RU2013139860A RU2013139860A RU 2013139860 A RU2013139860 A RU 2013139860A RU 2013139860/28 A RU2013139860/28 A RU 2013139860/28A RU 2013139860 A RU2013139860 A RU 2013139860A RU 2013139860 A RU2013139860 A RU 2013139860A
Authority
RU
Russia
Prior art keywords
microchip
image data
substrate
light
probes
Prior art date
Application number
RU2013139860/28A
Other languages
English (en)
Russian (ru)
Inventor
Кумие ОЗАКИ
Хиромити САСАМОТО
Кунихиса НАГИНО
Original Assignee
Торэй Индастриз, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Торэй Индастриз, Инк. filed Critical Торэй Индастриз, Инк.
Publication of RU2013139860A publication Critical patent/RU2013139860A/ru

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6486Measuring fluorescence of biological material, e.g. DNA, RNA, cells
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G16B25/30Microarray design
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00Apparatus for enzymology or microbiology
    • C12M1/34Measuring or testing with condition measuring or sensing means, e.g. colony counters
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N21/6452Individual samples arranged in a regular 2D-array, e.g. multiwell plates
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • G01N33/54373Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N37/00Details not covered by any other group of this subclass
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00497Features relating to the solid phase supports
    • B01J2219/00527Sheets
    • B01J2219/00529DNA chips
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/0054Means for coding or tagging the apparatus or the reagents
    • B01J2219/00572Chemical means
    • B01J2219/00576Chemical means fluorophore
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/0068Means for controlling the apparatus of the process
    • B01J2219/00693Means for quality control
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B60/00Apparatus specially adapted for use in combinatorial chemistry or with libraries
    • C40B60/12Apparatus specially adapted for use in combinatorial chemistry or with libraries for screening libraries
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N21/6456Spatial resolved fluorescence measurements; Imaging

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biophysics (AREA)
  • Evolutionary Biology (AREA)
  • Medical Informatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Theoretical Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Sustainable Development (AREA)
  • General Engineering & Computer Science (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
RU2013139860/28A 2011-01-28 2011-12-26 Способ анализа микрочипа и устройство считывания микрочипа RU2013139860A (ru)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP2011016690 2011-01-28
JP2011-016690 2011-01-28
JP2011-205865 2011-09-21
JP2011205865A JP5817378B2 (ja) 2011-01-28 2011-09-21 マイクロアレイの解析方法および読取り装置
PCT/JP2011/080007 WO2012101943A1 (ja) 2011-01-28 2011-12-26 マイクロアレイの解析方法および読取り装置

Publications (1)

Publication Number Publication Date
RU2013139860A true RU2013139860A (ru) 2015-03-10

Family

ID=46580525

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2013139860/28A RU2013139860A (ru) 2011-01-28 2011-12-26 Способ анализа микрочипа и устройство считывания микрочипа

Country Status (9)

Country Link
US (1) US9719929B2 (https=)
EP (1) EP2669662B1 (https=)
JP (1) JP5817378B2 (https=)
KR (1) KR101885939B1 (https=)
CN (1) CN103339493B (https=)
BR (1) BR112013019162A2 (https=)
CA (1) CA2825727C (https=)
RU (1) RU2013139860A (https=)
WO (1) WO2012101943A1 (https=)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2908089B1 (en) * 2012-10-12 2022-04-13 Toray Industries, Inc. Height difference detection method, microarray analysis method and fluorescence reading device
DE102013211090A1 (de) * 2013-06-14 2014-12-18 Robert Bosch Gmbh Erfassungssystem zum Erfassen einer Lötverbindung
KR101594523B1 (ko) * 2013-09-02 2016-02-16 한국광기술원 가시광 광학영상 및 비가시광 형광영상의 동시구현이 가능한 광대역 영상 획득투사장치
JP2015194379A (ja) * 2014-03-31 2015-11-05 株式会社ニコン バイオチップ及びバイオチップにおけるアライメントマークの検出方法
JP6448933B2 (ja) * 2014-07-09 2019-01-09 日本板硝子株式会社 蛍光検出用光学装置
JP6534318B2 (ja) * 2015-09-02 2019-06-26 アズビル株式会社 蛍光粒子の計測方法
NL2018852B1 (en) 2017-05-05 2018-11-14 Illumina Inc Optical distortion correction for imaged samples
JP2018124289A (ja) * 2018-04-10 2018-08-09 株式会社ニコン バイオチップ及びバイオチップにおけるアライメントマークの検出方法
CN109003910B (zh) * 2018-06-06 2020-07-14 广东利扬芯片测试股份有限公司 基于全自动探针台的不规则晶圆测试方法及其计算机可读存储介质
JP7141102B2 (ja) * 2018-11-26 2022-09-22 株式会社マルコム Led装置の発光特性測定装置
JP6664462B2 (ja) * 2018-12-05 2020-03-13 日本板硝子株式会社 蛍光検出用光学装置
CN113227342A (zh) * 2019-01-09 2021-08-06 株式会社日立高新技术 核酸分析用基板、核酸分析用流动池以及图像分析方法
JP2020106535A (ja) * 2020-02-18 2020-07-09 日本板硝子株式会社 蛍光検出用光学装置
KR20240022445A (ko) 2021-06-18 2024-02-20 하마마츠 포토닉스 가부시키가이샤 측정 장치
JP7700234B2 (ja) * 2021-06-18 2025-06-30 浜松ホトニクス株式会社 測定装置
CN117351077B (zh) * 2023-09-14 2024-07-02 广东凯普科技智造有限公司 一种点样仪动态预测的视觉修正方法

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6309601B1 (en) 1993-11-01 2001-10-30 Nanogen, Inc. Scanning optical detection system
JP3879037B2 (ja) * 2001-11-22 2007-02-07 独立行政法人理化学研究所 生体分子マイクロアレイのデータ収集方法
WO2003044527A1 (en) 2001-11-22 2003-05-30 Riken Substrate for biomolecule microarray, process for producing the same, biomolecule microarray and method of collecting data on biomolecule microarray
JP3670260B2 (ja) * 2002-02-14 2005-07-13 日本碍子株式会社 プローブ反応性チップ
US7200254B2 (en) 2002-02-14 2007-04-03 Ngk Insulators, Ltd. Probe reactive chip, sample analysis apparatus, and method thereof
US20030152255A1 (en) 2002-02-14 2003-08-14 Ngk Insulators, Ltd. Probe reactive chip, apparatus for analyzing sample and method thereof
JP4280720B2 (ja) 2002-02-14 2009-06-17 日本碍子株式会社 試料解析装置および試料解析方法
US7689022B2 (en) * 2002-03-15 2010-03-30 Affymetrix, Inc. System, method, and product for scanning of biological materials
JP4464664B2 (ja) 2003-06-13 2010-05-19 独立行政法人理化学研究所 生体分子マイクロアレイ用基板、生体分子マイクロアレイ、相互作用促進用装置および方法、ならびに、相互作用の検出方法
JP2005049282A (ja) * 2003-07-30 2005-02-24 Hamamatsu Photonics Kk 蛍光観察装置及びレーザ光照射装置
WO2008104922A1 (en) 2007-03-01 2008-09-04 Koninklijke Philips Electronics N.V. Grid pattern determination system
FR2916051A1 (fr) * 2007-05-07 2008-11-14 Beamind Soc Par Actions Simpli Procede et dispositif d'alignement d'un systeme de test avec un element electrique a tester
JP2009068995A (ja) * 2007-09-13 2009-04-02 Panasonic Corp マイクロアレイ装置
US20100204057A1 (en) 2009-02-10 2010-08-12 Samsung Electronics Co., Ltd. Substrate for microarray, method of manufacturing microarray using the same and method of obtaining light data from microarray
KR101513602B1 (ko) * 2009-02-11 2015-04-22 삼성전자주식회사 바이오칩 스캐닝 방법
JP5728381B2 (ja) * 2009-06-16 2015-06-03 東洋鋼鈑株式会社 マイクロアレイにおけるプローブ位置決定の方法
JP5409237B2 (ja) * 2009-09-28 2014-02-05 キヤノン株式会社 パターン検出装置、その処理方法及びプログラム
JP2011182705A (ja) * 2010-03-09 2011-09-22 Toray Ind Inc Dnaチップ解析方法および解析装置

Also Published As

Publication number Publication date
CN103339493A (zh) 2013-10-02
BR112013019162A2 (pt) 2018-06-05
CA2825727A1 (en) 2012-08-02
EP2669662A4 (en) 2017-12-27
CA2825727C (en) 2019-03-19
EP2669662B1 (en) 2019-02-20
CN103339493B (zh) 2015-06-10
EP2669662A1 (en) 2013-12-04
US9719929B2 (en) 2017-08-01
KR20130142179A (ko) 2013-12-27
JP5817378B2 (ja) 2015-11-18
KR101885939B1 (ko) 2018-08-06
WO2012101943A1 (ja) 2012-08-02
US20130303403A1 (en) 2013-11-14
JP2012168159A (ja) 2012-09-06

Similar Documents

Publication Publication Date Title
RU2013139860A (ru) Способ анализа микрочипа и устройство считывания микрочипа
JP2012168159A5 (https=)
AU2018369859B2 (en) Sample carrier for optical measurements
MX2021000993A (es) Sistema y metodo para medir una superficie en láminas de vidrio contorneado.
CN107077732A (zh) 用于对数字显微镜计算聚焦变化的系统及方法
JP2020514751A (ja) ラテラルフロー試験システム
ATE513202T1 (de) Verfahren und vorrichtung zur dreidimensionalen rekonstruktion der verteilung von fluoreszierenden elementen
EP2784480A3 (en) Blood cell analyzer and blood cell analyzing method
JP2011149822A (ja) 光学的測定装置及び光学的測定方法
KR20150064067A (ko) 검출 방법, 마이크로어레이의 해석 방법 및 형광 판독 장치
MX2017007791A (es) Metodo y dispositivo para determinar el tiempo de coagulacion de una muestra de sangre, y recipiente de reaccion.
EP4220158A3 (en) Urine specimen analysis device and urine specimen analysis method
EP2669739A3 (en) Measuring method, and exposure method and apparatus
CN109844606B (zh) 试样观察装置及试样观察方法
US20150277092A1 (en) Phase mask imaging
EP2784479A3 (en) Blood cell analyzer and blood cell analyzing method
ATE447355T1 (de) Kombiniertes gerät zum messen von blutzucker aus augenflüssigkeit
BR112018017312A2 (pt) método e aparelho para detecção de precursores de acrilamida em batatas cruas, máquina de classificação, e, meio legível por computador
EP3276388A1 (en) Light sheet microscope and control method of light sheet microscope
FR3013128B1 (fr) Dispositif et methode de mise au point tridimensionnelle pour microscope
JP2019522797A (ja) 貫通孔の幾何学的パラメータ測定方法およびシステム
JP2009162660A (ja) 検出方法及び検出装置
JPWO2004095009A1 (ja) 光学検査装置
EP4671760A3 (en) Simultaneous measurement of multiple analytes of a liquid assay
JP2018533014A (ja) 試料媒質の波長依存性屈折率を決定するための光学顕微鏡及び方法

Legal Events

Date Code Title Description
FA93 Acknowledgement of application withdrawn (no request for examination)

Effective date: 20141229