RU2013107451A - Комбинация силоксана и активного ингредиента для лечения стоматологических заболеваний - Google Patents
Комбинация силоксана и активного ингредиента для лечения стоматологических заболеваний Download PDFInfo
- Publication number
- RU2013107451A RU2013107451A RU2013107451/04A RU2013107451A RU2013107451A RU 2013107451 A RU2013107451 A RU 2013107451A RU 2013107451/04 A RU2013107451/04 A RU 2013107451/04A RU 2013107451 A RU2013107451 A RU 2013107451A RU 2013107451 A RU2013107451 A RU 2013107451A
- Authority
- RU
- Russia
- Prior art keywords
- composition
- active ingredient
- pharmacologically active
- composition according
- antibiotic
- Prior art date
Links
- 208000014151 Stomatognathic disease Diseases 0.000 title claims abstract 4
- -1 SILOXAN Chemical class 0.000 title 1
- 239000004480 active ingredient Substances 0.000 title 1
- 239000000203 mixture Substances 0.000 claims abstract 30
- 239000002831 pharmacologic agent Substances 0.000 claims abstract 17
- KPUWHANPEXNPJT-UHFFFAOYSA-N disiloxane Chemical class [SiH3]O[SiH3] KPUWHANPEXNPJT-UHFFFAOYSA-N 0.000 claims abstract 9
- 230000003115 biocidal effect Effects 0.000 claims abstract 8
- 239000008194 pharmaceutical composition Substances 0.000 claims abstract 7
- 208000018035 Dental disease Diseases 0.000 claims abstract 3
- 239000003242 anti bacterial agent Substances 0.000 claims abstract 2
- 229960003722 doxycycline Drugs 0.000 claims abstract 2
- XQTWDDCIUJNLTR-CVHRZJFOSA-N doxycycline monohydrate Chemical compound O.O=C1C2=C(O)C=CC=C2[C@H](C)[C@@H]2C1=C(O)[C@]1(O)C(=O)C(C(N)=O)=C(O)[C@@H](N(C)C)[C@@H]1[C@H]2O XQTWDDCIUJNLTR-CVHRZJFOSA-N 0.000 claims abstract 2
- 229940124307 fluoroquinolone Drugs 0.000 claims abstract 2
- 239000002271 gyrase inhibitor Substances 0.000 claims abstract 2
- HMMGMWAXVFQUOA-UHFFFAOYSA-N octamethylcyclotetrasiloxane Chemical group C[Si]1(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O1 HMMGMWAXVFQUOA-UHFFFAOYSA-N 0.000 claims abstract 2
- 230000035515 penetration Effects 0.000 claims abstract 2
- 230000002265 prevention Effects 0.000 claims abstract 2
- 208000002925 dental caries Diseases 0.000 claims 2
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 239000002552 dosage form Substances 0.000 claims 1
- 229960004023 minocycline Drugs 0.000 claims 1
- DYKFCLLONBREIL-KVUCHLLUSA-N minocycline Chemical compound C([C@H]1C2)C3=C(N(C)C)C=CC(O)=C3C(=O)C1=C(O)[C@@]1(O)[C@@H]2[C@H](N(C)C)C(O)=C(C(N)=O)C1=O DYKFCLLONBREIL-KVUCHLLUSA-N 0.000 claims 1
- FABPRXSRWADJSP-MEDUHNTESA-N moxifloxacin Chemical compound COC1=C(N2C[C@H]3NCCC[C@H]3C2)C(F)=CC(C(C(C(O)=O)=C2)=O)=C1N2C1CC1 FABPRXSRWADJSP-MEDUHNTESA-N 0.000 claims 1
- 229960003702 moxifloxacin Drugs 0.000 claims 1
- 208000028169 periodontal disease Diseases 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/695—Silicon compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K6/00—Preparations for dentistry
- A61K6/50—Preparations specially adapted for dental root treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K6/00—Preparations for dentistry
- A61K6/60—Preparations for dentistry comprising organic or organo-metallic additives
- A61K6/69—Medicaments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Dental Preparations (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10007536A EP2409702A1 (en) | 2010-07-21 | 2010-07-21 | Combination of siloxane and active ingredient for treating dental disorder of hard tissues |
| EP10007536.5 | 2010-07-21 | ||
| PCT/EP2011/061953 WO2012010478A1 (en) | 2010-07-21 | 2011-07-13 | Combination of siloxane and active ingredient for treating dental disorder |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2013107451A true RU2013107451A (ru) | 2014-08-27 |
Family
ID=43038027
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2013107451/04A RU2013107451A (ru) | 2010-07-21 | 2011-07-13 | Комбинация силоксана и активного ингредиента для лечения стоматологических заболеваний |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20130184239A1 (enExample) |
| EP (2) | EP2409702A1 (enExample) |
| JP (1) | JP2013531048A (enExample) |
| KR (1) | KR20130043203A (enExample) |
| CN (1) | CN103096890A (enExample) |
| AU (1) | AU2011281719A1 (enExample) |
| BR (1) | BR112013001492A2 (enExample) |
| CA (1) | CA2805980A1 (enExample) |
| MX (1) | MX2013000800A (enExample) |
| RU (1) | RU2013107451A (enExample) |
| WO (1) | WO2012010478A1 (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2699371C1 (ru) * | 2018-12-06 | 2019-09-05 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Кубанский государственный медицинский университет" Министерства здравоохранения Российской Федерации (ФГБОУ ВО КубГМУ Минздрава России) | Стоматологическая паста для временного пломбирования каналов корней зубов при лечении хронического деструктивного периодонтита |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH11180841A (ja) * | 1997-12-15 | 1999-07-06 | Lion Corp | 口腔用組成物 |
| DE19962470A1 (de) * | 1999-12-22 | 2001-07-12 | Schulz Hans Herrmann | Verwendung von Chemotherapeutika |
| JP2001354535A (ja) * | 2000-06-13 | 2001-12-25 | Lion Corp | 口腔用組成物 |
| JP2002179569A (ja) | 2000-12-12 | 2002-06-26 | Lion Corp | 口腔用組成物 |
| ES2272814T3 (es) | 2001-11-13 | 2007-05-01 | GE BAYER SILICONES GMBH & CO. KG | Empleo de siloxanos como soportes evaporables. |
| CA2467244C (en) | 2001-11-15 | 2011-01-04 | Laboratorios Miret S.A. | Use of cationic surfactant as antimicrobial activity enhancer in deodorants and oral care |
| JP2004107310A (ja) * | 2002-09-13 | 2004-04-08 | Lion Corp | 口腔用組成物 |
| WO2007013175A1 (ja) | 2005-07-29 | 2007-02-01 | Takeshi Tanaka | 歯用漂白剤 |
| GB0518769D0 (en) | 2005-09-14 | 2005-10-19 | Medpharm Ltd | Topical formulations |
-
2010
- 2010-07-21 EP EP10007536A patent/EP2409702A1/en not_active Withdrawn
-
2011
- 2011-07-13 KR KR1020137004211A patent/KR20130043203A/ko not_active Withdrawn
- 2011-07-13 BR BR112013001492A patent/BR112013001492A2/pt not_active IP Right Cessation
- 2011-07-13 US US13/811,140 patent/US20130184239A1/en not_active Abandoned
- 2011-07-13 CN CN2011800454969A patent/CN103096890A/zh active Pending
- 2011-07-13 MX MX2013000800A patent/MX2013000800A/es not_active Application Discontinuation
- 2011-07-13 RU RU2013107451/04A patent/RU2013107451A/ru not_active Application Discontinuation
- 2011-07-13 AU AU2011281719A patent/AU2011281719A1/en not_active Abandoned
- 2011-07-13 WO PCT/EP2011/061953 patent/WO2012010478A1/en not_active Ceased
- 2011-07-13 CA CA2805980A patent/CA2805980A1/en not_active Abandoned
- 2011-07-13 EP EP11730703.3A patent/EP2595626A1/en not_active Withdrawn
- 2011-07-13 JP JP2013520068A patent/JP2013531048A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2013531048A (ja) | 2013-08-01 |
| WO2012010478A1 (en) | 2012-01-26 |
| EP2409702A1 (en) | 2012-01-25 |
| CN103096890A (zh) | 2013-05-08 |
| AU2011281719A1 (en) | 2013-02-21 |
| KR20130043203A (ko) | 2013-04-29 |
| CA2805980A1 (en) | 2012-01-26 |
| BR112013001492A2 (pt) | 2016-05-31 |
| US20130184239A1 (en) | 2013-07-18 |
| MX2013000800A (es) | 2013-02-27 |
| EP2595626A1 (en) | 2013-05-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| RU2012146986A (ru) | Цефемовые соединения, содержащие катехольную группу | |
| MY151430A (en) | Anti-caries oral care compositions with xylitol | |
| RU2014141362A (ru) | Комбинированная терапия пролиферативных нарушений | |
| EA200700099A1 (ru) | Производные пиридина | |
| EA201201414A1 (ru) | КОМБИНАЦИИ, СОДЕРЖАЩИЕ ЗАМЕЩЕННЫЕ 2,3-ДИГИДРОИМИДАЗО[1,2-c]ХИНАЗОЛИНЫ | |
| RU2013111077A (ru) | Дипептидное пролекарство, его применение и лекарственное средство | |
| ATE517882T1 (de) | Chinolinderivate | |
| EA200600811A1 (ru) | НОВЫЕ ПРОИЗВОДНЫЕ ТЕТРАГИДРОСПИРО {ПИПЕРИДИН-2,7'-ПИРРОЛО [3,2-b]ПИРИДИНА} И НОВЫЕ ПРОИЗВОДНЫЕ ИНДОЛА, ПРИМЕНЕНИЕ ДЛЯ ЛЕЧЕНИЯ РАССТРОЙСТВ, СВЯЗАННЫХ С 5-HT-РЕЦЕПТОРОМ | |
| RU2014111069A (ru) | Лекарственные формы ингибитора гистондиацетилазы в комбинации с бендамутином и их применение | |
| CO5590918A2 (es) | Formulaciones | |
| MX2013003695A (es) | Combinaciones que contienen n-(2-arilamino) arilsulfonamida sustituida. | |
| RU2013127655A (ru) | Фармацевтическая комбинация паклитаксела и ингибитора cdk | |
| RU2006144069A (ru) | Режим приема контрацептива с антагонистом рецептора прогестерона и набор для приема | |
| RU2011112684A (ru) | АГЕНТ, СПОСОБСТВУЮЩИЙ РОСТУ ВОЛОС, СОДЕРЖАЩИЙ В КАЧЕСТВЕ АКТИВНОГО ИНГРЕДИЕНТА ПРОИЗВОДНОЕ 15,15-ДИФТОРПРОСТАГЛАНДИНА F2α | |
| RU99101081A (ru) | Режим введения ингибиторов н+, к+-атфазы | |
| EA201071352A1 (ru) | Трициклические азотсодержащие соединения и их применение в качестве бактерицидных средств | |
| RU2009128970A (ru) | Производные изосорбидмононитрата для лечения кишечных заболеваний | |
| AR045939A1 (es) | Derivados de bencimidazolona y quinazolinona como agonistas de los receptores orl 1 humanos | |
| RU2013107451A (ru) | Комбинация силоксана и активного ингредиента для лечения стоматологических заболеваний | |
| RU2013148627A (ru) | Производные тиено [2, 3-d] пиримидина и их применение для лечения аритмии | |
| RU2010129038A (ru) | Соединения, предназначенные для лечения рака | |
| RU2012106827A (ru) | Применение производных 5н-дибенз/в, f/азепин-5-карбоксамида для лечения фибромиалгии | |
| DK2091520T3 (da) | Oral doseringsform omfattende trisubstituerede glycerol-forbindelser | |
| DE602005017629D1 (de) | Pharmazeutische zusammensetzungen zur behandlung von leishmaniasis | |
| RU2008102912A (ru) | Сочетание ингибиторов бетта-лактазмы бициклического 6-алкилиденпенема с бетта-лактанным антибиотиком: антибиотик широкого спектра |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA92 | Acknowledgement of application withdrawn (lack of supplementary materials submitted) |
Effective date: 20151109 |