RU2012134369A - Биомаркеры иммуномодулирующих эффектов у людей, подвергнутых лечению антиметаллами против cd200 - Google Patents

Биомаркеры иммуномодулирующих эффектов у людей, подвергнутых лечению антиметаллами против cd200 Download PDF

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Publication number
RU2012134369A
RU2012134369A RU2012134369/15A RU2012134369A RU2012134369A RU 2012134369 A RU2012134369 A RU 2012134369A RU 2012134369/15 A RU2012134369/15 A RU 2012134369/15A RU 2012134369 A RU2012134369 A RU 2012134369A RU 2012134369 A RU2012134369 A RU 2012134369A
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antibody
cancer
binding fragment
patient
seq
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RU2012134369/15A
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Russian (ru)
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МАКНАЙТ Сьюзан ФААС
Роксанне КОФИЛЛ
Ян Ян
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Алексион Фармасьютикалз, Инк
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    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57492—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds localized on the membrane of tumor or cancer cells
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  • Orthopedic Medicine & Surgery (AREA)
  • Pulmonology (AREA)
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  • Rheumatology (AREA)
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RU2012134369/15A 2010-01-11 2011-01-11 Биомаркеры иммуномодулирующих эффектов у людей, подвергнутых лечению антиметаллами против cd200 RU2012134369A (ru)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US29406610P 2010-01-11 2010-01-11
US61/294,066 2010-01-11
US33799710P 2010-02-11 2010-02-11
US61/337,997 2010-02-11
US40144210P 2010-08-12 2010-08-12
US61/401,442 2010-08-12
US41697410P 2010-11-24 2010-11-24
US61/416,974 2010-11-24
PCT/US2011/020750 WO2011085343A1 (en) 2010-01-11 2011-01-11 Biomarkers of immunomodulatory effects in humans treated with anti-cd200 antibodies

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RU2012134369A true RU2012134369A (ru) 2014-02-20

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US (2) US9180186B2 (OSRAM)
EP (1) EP2523976B1 (OSRAM)
JP (2) JP6012473B2 (OSRAM)
KR (1) KR20130005264A (OSRAM)
CN (1) CN102906115A (OSRAM)
AU (1) AU2011203879A1 (OSRAM)
CA (1) CA2786692A1 (OSRAM)
IN (1) IN2012DN06309A (OSRAM)
MX (1) MX2012008108A (OSRAM)
NZ (1) NZ601111A (OSRAM)
RU (1) RU2012134369A (OSRAM)
SG (1) SG182408A1 (OSRAM)
WO (1) WO2011085343A1 (OSRAM)

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CN102698266A (zh) * 2012-05-15 2012-10-03 中国医学科学院北京协和医院 Cd200在制备系统性红斑狼疮治疗药物中的应用
AU2013285355A1 (en) 2012-07-06 2015-01-29 Genmab B.V. Dimeric protein with triple mutations
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WO2017124001A2 (en) * 2016-01-14 2017-07-20 Memorial Sloan-Kettering Cancer Center T cell receptor-like antibodies specific for foxp3-derived peptides
GB201608197D0 (en) * 2016-05-10 2016-06-22 Ducentis Biotherapeutics Ltd Novel proteins
WO2018075408A1 (en) 2016-10-17 2018-04-26 Alexion Pharmaceuticals, Inc. Methods of treating acute myeloid leukemia (aml) with combinations of anti-cd200 antibodies, cytarabine, and daunorubicin
WO2018102594A1 (en) * 2016-12-01 2018-06-07 Alexion Pharmaceuticals, Inc. Methods of treating solid tumors with anti-cd200 antibodies
AU2018266711B2 (en) * 2017-05-08 2025-02-06 Adimab, Llc Anti-CD3-binding domains and antibodies comprising them, and methods for their generation and use
US11761963B2 (en) 2017-09-27 2023-09-19 Alexion Pharmaceuticals, Inc. Biomarker signature for predicting tumor response to anti-CD200 therapy
WO2019126133A1 (en) 2017-12-20 2019-06-27 Alexion Pharmaceuticals, Inc. Liquid formulations of anti-cd200 antibodies
US11802154B2 (en) 2017-12-20 2023-10-31 Alexion Pharmaceuticals, Inc. Humanized anti-CD200 antibodies and uses thereof
TWI749367B (zh) * 2018-09-14 2021-12-11 美商美國禮來大藥廠 Cd200r促效劑抗體及其用途
AU2024237816A1 (en) * 2023-03-10 2025-09-18 Ultragenyx Pharmaceutical Inc. Human fgf23-binding antibodies with improved affinity and efficacy

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