RU2012129418A - METHOD FOR MODELING CHRONIC INFLAMMATORY DISEASES OF FEMALE GENITAL ORGANS IN EXPERIMENT - Google Patents
METHOD FOR MODELING CHRONIC INFLAMMATORY DISEASES OF FEMALE GENITAL ORGANS IN EXPERIMENT Download PDFInfo
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- RU2012129418A RU2012129418A RU2012129418/14A RU2012129418A RU2012129418A RU 2012129418 A RU2012129418 A RU 2012129418A RU 2012129418/14 A RU2012129418/14 A RU 2012129418/14A RU 2012129418 A RU2012129418 A RU 2012129418A RU 2012129418 A RU2012129418 A RU 2012129418A
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Abstract
1. Способ моделирования хронических воспалительных заболеваний женских половых органов в эксперименте путем аутотрансплантации участков эндометрия, выделенных из маточного рога к париетальной брюшине, отличающийся тем, что для аутотрансплантации берут прямоугольные участки эндометрия размером 2×3 мм и подшивают их микрохирургическими инструментами атравматическим синтетическим нерассасывающимся монофиламентным шовным материалом 9/0 четырьмя швами по углам участка эндометрия двумя двойными узлами в каждом шве, проводят пред- и послеоперационную эстрогенизацию животного по следующей схеме: введение через день по 1,0 мл 0,1% синестрола внутримышечно один раз в день, начиная за 7 дней до аутотрансплантации (в 7-ой день, в 5-ый день, в 3-ий день, в день перед операцией) и в день операции, после операции синестрол вводят в той же дозе однократно на 2-й, 4-й и 6-й день.2. Способ моделирования хронических воспалительных заболеваний женских половых органов в эксперименте по п.1, отличающийся тем, что фиксацию участков эндометрия размером 2×3 мм к париетальной брюшине осуществляют общехирургическими инструментами синтетическим нерассасывающимся шовным материалом 4/0 четырьмя швами по углам участка эндометрия тремя узлами в каждом шве.1. A method for modeling chronic inflammatory diseases of the female genital organs in an experiment by means of autotransplantation of endometrial sites isolated from the uterine horn to the parietal peritoneum, characterized in that for autotransplantation, rectangular areas of the endometrium 2 × 3 mm in size are taken and the atraumatic synthetic non-absorbable monofilament is hemmed with microsurgical instruments material 9/0 with four sutures at the corners of the endometrial site with two double nodes in each suture, conduct pre- and last surgical estrogenization of the animal according to the following scheme: administration of 1.0 ml of 0.1% sinestrol intramuscularly once a day, starting 7 days before autotransplantation (on the 7th day, on the 5th day, on the 3rd day , on the day before surgery) and on the day of surgery, after surgery, sinestrol is administered in the same dose once on the 2nd, 4th and 6th day. 2. A method for modeling chronic inflammatory diseases of the female genital organs in the experiment according to claim 1, characterized in that the fixation of the endometrial portions of 2 × 3 mm to the parietal peritoneum is performed with general surgical instruments with synthetic non-absorbable suture material 4/0 with four sutures at the corners of the endometrial region with three nodes in each seam.
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RU2012129418/14A RU2533739C2 (en) | 2012-07-11 | 2012-07-11 | Method for simulating chronic inflammatory diseases of female genital organs experimentally |
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RU2012129418/14A RU2533739C2 (en) | 2012-07-11 | 2012-07-11 | Method for simulating chronic inflammatory diseases of female genital organs experimentally |
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RU2012129418A true RU2012129418A (en) | 2014-01-20 |
RU2533739C2 RU2533739C2 (en) | 2014-11-20 |
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Cited By (1)
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CN112164466A (en) * | 2020-09-17 | 2021-01-01 | 顺德职业技术学院 | Tissue inflammation overall process simulation method and system |
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RU2580986C1 (en) * | 2015-02-18 | 2016-04-10 | Государственное бюджетное образовательное учреждение высшего профессионального образования "Волгоградский государственный медицинский университет" Министерства здравоохранения Российской Федерации | Method for simulating experimental chronic inflammation of endometrium in rats |
RU2600926C2 (en) * | 2015-04-01 | 2016-10-27 | федеральное государственное бюджетное учреждение "Санкт-Петербургский научно-исследовательский институт фтизиопульмонологии" Министерства здравоохранения Российской Федерации | Method for modeling tuberculosis of female genital organs |
RU2740423C1 (en) * | 2020-07-22 | 2021-01-14 | федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр онкологии" Министерства здравоохранения Российской Федерации | Method of selecting optimal access for orthotopic transplantation of human ovarian cancer tumor into ovary of immune-deficient mouse |
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RU2142163C1 (en) * | 1996-07-17 | 1999-11-27 | Институт клинической и экспериментальной лимфологии СО РАМН | Method for modelling inflammatory diseases in female genital organs |
RU2224297C1 (en) * | 2002-06-28 | 2004-02-20 | Производственное учреждение системы высшего и послевузовского профессионального образования "Сибирский государственный медицинский университет" | Method for modeling chronic uterine appendages inflammation |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112164466A (en) * | 2020-09-17 | 2021-01-01 | 顺德职业技术学院 | Tissue inflammation overall process simulation method and system |
CN112164466B (en) * | 2020-09-17 | 2023-11-21 | 顺德职业技术学院 | Tissue inflammation overall process simulation method and system |
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