RU2012119249A - Соединения кумарина в качестве модуляторов рецепторов для терапевтического использования - Google Patents

Соединения кумарина в качестве модуляторов рецепторов для терапевтического использования Download PDF

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RU2012119249A
RU2012119249A RU2012119249/04A RU2012119249A RU2012119249A RU 2012119249 A RU2012119249 A RU 2012119249A RU 2012119249/04 A RU2012119249/04 A RU 2012119249/04A RU 2012119249 A RU2012119249 A RU 2012119249A RU 2012119249 A RU2012119249 A RU 2012119249A
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oxo
methoxy
chromene
carboxamide
propyl
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RU2012119249/04A
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Russian (ru)
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Тод М. ХЕЙДЕЛБАУ
Джон Р. КАППИЕЛЛО
Фонг НГУЕН
Дарио Г. ГОМЕЗ
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Аллерган, Инк.
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    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • A61K31/37—Coumarins, e.g. psoralen
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  • Communicable Diseases (AREA)
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  • Transplantation (AREA)
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
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RU2012119249/04A 2009-10-23 2010-10-20 Соединения кумарина в качестве модуляторов рецепторов для терапевтического использования RU2012119249A (ru)

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US25423609P 2009-10-23 2009-10-23
US61/254,236 2009-10-23
PCT/US2010/053363 WO2011050054A2 (en) 2009-10-23 2010-10-20 Coumarin compounds as receptor modulators with therapeutic utility

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EP (1) EP2491023B1 (enExample)
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CN (1) CN102686574A (enExample)
BR (1) BR112012009670A2 (enExample)
CA (1) CA2778611A1 (enExample)
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KR20120075481A (ko) * 2009-10-23 2012-07-06 알러간, 인코포레이티드 치료적 유용성을 갖는 수용체 조절제로서 쿠마린 화합물
CN107868069A (zh) * 2017-10-31 2018-04-03 山东新华制药股份有限公司 7‑羟基‑8‑甲基‑6‑硝基‑2‑氧‑2h‑苯并吡喃‑3‑羧酸的制备工艺
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MX2020007948A (es) 2018-02-02 2020-12-10 Univ Kyoto Medicamento para prevenir o tratar una enfermedad oftalmica asociada con neovascularizacion intraocular mejorada y/o permeabilidad vascular intraocular.
CN110713497A (zh) * 2019-10-30 2020-01-21 成都海杰亚医药科技有限公司 一种Brigatinib的中间体2-氨基苯基二甲基氧化膦制备方法
US12273086B2 (en) * 2022-08-31 2025-04-08 Apple Inc. Adjustable radio-frequency splitter-combiner
CN116478173B (zh) * 2023-04-20 2025-03-25 山西师范大学 一种靶向高尔基体监测极性的荧光探针及其制备与应用

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CN1506359A (zh) 2002-12-05 2004-06-23 �й�ҽѧ��ѧԺҩ���о��� 新的香豆素酰胺衍生物及其制法和其药物组合物与用途
AU2004234067B2 (en) * 2003-04-30 2008-02-28 Novartis Ag Aminopropanol derivatives as sphingosine-1-phosphate receptor modulators
AU2004234066B2 (en) * 2003-04-30 2008-02-21 Novartis Ag Amino-propanol derivatives as sphingosine-1-phosphate receptor modulator
GB0607389D0 (en) 2006-04-12 2006-05-24 Novartis Ag Organic compounds
KR20090114383A (ko) * 2007-02-02 2009-11-03 노파르티스 아게 크로멘 ｓ1ｐ1 수용체 길항제
US8399448B2 (en) 2007-08-08 2013-03-19 Merck Serono Sa 6-amino-pyrimidine-4-carboxamide derivatives and related compounds which bind to the sphingosine 1-phosphate (S1P) receptor for the treatment of multiple sclerosis
KR20120075481A (ko) * 2009-10-23 2012-07-06 알러간, 인코포레이티드 치료적 유용성을 갖는 수용체 조절제로서 쿠마린 화합물

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US9073888B2 (en) 2015-07-07
US20120328661A1 (en) 2012-12-27
WO2011050054A3 (en) 2011-06-09
WO2011050054A2 (en) 2011-04-28
EP2491023A2 (en) 2012-08-29
US9572792B2 (en) 2017-02-21
CA2778611A1 (en) 2011-04-28
BR112012009670A2 (pt) 2016-05-17
JP2013508385A (ja) 2013-03-07
US20150265573A1 (en) 2015-09-24
EP2491023B1 (en) 2014-12-31

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