RU2010116245A - НУКЛЕИНОВЫЕ КИСЛОТЫ, СВЯЗЫВАЮЩИЕ C5a - Google Patents
НУКЛЕИНОВЫЕ КИСЛОТЫ, СВЯЗЫВАЮЩИЕ C5a Download PDFInfo
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- RU2010116245A RU2010116245A RU2010116245/10A RU2010116245A RU2010116245A RU 2010116245 A RU2010116245 A RU 2010116245A RU 2010116245/10 A RU2010116245/10 A RU 2010116245/10A RU 2010116245 A RU2010116245 A RU 2010116245A RU 2010116245 A RU2010116245 A RU 2010116245A
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
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- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/713—Double-stranded nucleic acids or oligonucleotides
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/16—Aptamers
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/31—Chemical structure of the backbone
- C12N2310/318—Chemical structure of the backbone where the PO2 is completely replaced, e.g. MMI or formacetal
- C12N2310/3183—Diol linkers, e.g. glycols or propanediols
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- C12N2310/00—Structure or type of the nucleic acid
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- C12N2310/32—Chemical structure of the sugar
- C12N2310/323—Chemical structure of the sugar modified ring structure
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
- Y10T436/143333—Saccharide [e.g., DNA, etc.]
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Diabetes (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Pulmonology (AREA)
- Neurology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Hematology (AREA)
- Dermatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Biochemistry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Neurosurgery (AREA)
- Biophysics (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Endocrinology (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07018750 | 2007-09-24 | ||
| EP07018750.5 | 2007-09-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2010116245A true RU2010116245A (ru) | 2011-11-10 |
Family
ID=40174751
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2010116245/10A RU2010116245A (ru) | 2007-09-24 | 2008-09-24 | НУКЛЕИНОВЫЕ КИСЛОТЫ, СВЯЗЫВАЮЩИЕ C5a |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US8507456B2 (enExample) |
| EP (2) | EP2562256A3 (enExample) |
| JP (1) | JP5798320B2 (enExample) |
| KR (1) | KR20100072185A (enExample) |
| CN (1) | CN101809154A (enExample) |
| AU (1) | AU2008303775A1 (enExample) |
| BR (1) | BRPI0817260A2 (enExample) |
| CA (1) | CA2700441A1 (enExample) |
| MX (1) | MX2010003109A (enExample) |
| RU (1) | RU2010116245A (enExample) |
| WO (1) | WO2009040113A2 (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2564855C2 (ru) * | 2011-04-26 | 2015-10-10 | ОБЩЕСТВО С ОГРАНИЧЕННОЙ ОТВЕТСТВЕННОСТЬЮ "НоваМедика" | Способ получения пэгилированных олигонуклеотидов |
| RU2736499C1 (ru) * | 2017-02-23 | 2020-11-17 | Гуанчжоу Селлпротек Фармасьютикал Ко., Лтд | Специфические ингибиторы гексокиназы-2 для применения при остром повреждении центральной нервной системы |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8066757B2 (en) | 2007-10-17 | 2011-11-29 | Mindframe, Inc. | Blood flow restoration and thrombus management methods |
| US20120065254A1 (en) * | 2009-03-23 | 2012-03-15 | Noxxon Pharma Ag | C5A binding nucleic acids and the use thereof |
| EP3187877A1 (en) * | 2009-09-25 | 2017-07-05 | XOMA Technology Ltd. | Screening methods |
| WO2012168803A2 (en) | 2011-06-07 | 2012-12-13 | Koninklijke Philips Electronics N.V. | Providing nucleotide sequence data |
| US10531655B2 (en) | 2011-12-02 | 2020-01-14 | The Regents Of The University Of California | Reperfusion protection solution and uses thereof |
| BR112014016877B1 (pt) * | 2012-01-10 | 2022-03-15 | Aptarion Biotech Ag | Molécula de l-ácido nucleico capaz de se ligar a c5a humana, seus usos, bem como composição farmacêutica, complexo, método para a seleção de um antagonista de uma atividade mediada por c5a e kit para a detecção de c5a |
| CN105849323A (zh) | 2013-10-28 | 2016-08-10 | 多茨设备公司 | 过敏原检测 |
| US10238700B2 (en) | 2014-01-02 | 2019-03-26 | Genelux Corporation | Oncolytic virus adjunct therapy with agents that increase virus infectivity |
| EP3553521A1 (en) * | 2018-04-12 | 2019-10-16 | Koninklijke Philips N.V. | Gingivitis diagnostic methods, uses and kits |
| WO2025196240A1 (en) | 2024-03-20 | 2025-09-25 | Aptarion Biotech Ag | Method of treating a disorder with a c5a inhibitor |
| EP4620474A1 (en) | 2024-03-20 | 2025-09-24 | APTARION biotech AG | Method of treating a disorder with a c5a inhibitor |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6395888B1 (en) * | 1996-02-01 | 2002-05-28 | Gilead Sciences, Inc. | High affinity nucleic acid ligands of complement system proteins |
| US6011020A (en) | 1990-06-11 | 2000-01-04 | Nexstar Pharmaceuticals, Inc. | Nucleic acid ligand complexes |
| US6395029B1 (en) | 1999-01-19 | 2002-05-28 | The Children's Hospital Of Philadelphia | Sustained delivery of polyionic bioactive agents |
| US6652886B2 (en) | 2001-02-16 | 2003-11-25 | Expression Genetics | Biodegradable cationic copolymers of poly (alkylenimine) and poly (ethylene glycol) for the delivery of bioactive agents |
| EP1306382A1 (de) | 2001-10-26 | 2003-05-02 | Noxxon Pharma AG | Modifizierte L-Nukleinsäure |
| EP2138575B8 (en) | 2002-02-20 | 2013-07-24 | Mersana Therapeutics, Inc. | Conjugates comprising a biodegradable polymer and uses therefor |
| KR20060015505A (ko) | 2003-04-13 | 2006-02-17 | 엔존 파마슈티컬즈, 인코포레이티드 | 올리고뉴클레오타이드 전구약물 |
| GB0314472D0 (en) | 2003-06-20 | 2003-07-23 | Warwick Effect Polymers Ltd | Polymer |
| US20070116710A1 (en) * | 2004-02-03 | 2007-05-24 | Leonard Bell | Methods of treating hemolytic anemia |
| US20090281296A1 (en) | 2004-02-09 | 2009-11-12 | Supramol Parenteral Colloid Gmbh | Process for the production of conjugates from polysaccharides and polynucelotides |
| US7803931B2 (en) | 2004-02-12 | 2010-09-28 | Archemix Corp. | Aptamer therapeutics useful in the treatment of complement-related disorders |
| PL3385384T3 (pl) * | 2004-02-12 | 2021-03-08 | Archemix Llc | Aptamerowe środki terapeutyczne użyteczne w leczeniu zaburzeń powiązanych z dopełniaczem |
| ES2741524T3 (es) | 2004-03-23 | 2020-02-11 | Ascendis Pharma Gmbh | Profármaco polimérico con un enlazador autoinmolador |
| WO2006052790A2 (en) | 2004-11-05 | 2006-05-18 | The Children's Hospital Of Philadelphia | Biodegradable linkers for molecular therapies |
| HUE026496T2 (en) * | 2006-03-08 | 2016-06-28 | Archemix Llc | Complement-binding aptamers and anti-C5 agents for treating eye diseases |
| CN101534643A (zh) | 2006-09-15 | 2009-09-16 | 安佐制药股份有限公司 | 用于递送寡核苷酸的基于位阻酯的生物可降解连接体 |
| EP2407558A1 (en) | 2006-10-31 | 2012-01-18 | Noxxon Pharma AG | Methods for the detection of a single- or double-stranded nucleic acid molecule |
| US20120065254A1 (en) * | 2009-03-23 | 2012-03-15 | Noxxon Pharma Ag | C5A binding nucleic acids and the use thereof |
-
2008
- 2008-09-24 RU RU2010116245/10A patent/RU2010116245A/ru not_active Application Discontinuation
- 2008-09-24 US US12/679,307 patent/US8507456B2/en not_active Expired - Fee Related
- 2008-09-24 EP EP12006735.0A patent/EP2562256A3/en not_active Withdrawn
- 2008-09-24 BR BRPI0817260-9A2A patent/BRPI0817260A2/pt not_active IP Right Cessation
- 2008-09-24 KR KR1020107005454A patent/KR20100072185A/ko not_active Withdrawn
- 2008-09-24 CN CN200880108439A patent/CN101809154A/zh active Pending
- 2008-09-24 CA CA2700441A patent/CA2700441A1/en not_active Abandoned
- 2008-09-24 WO PCT/EP2008/008097 patent/WO2009040113A2/en not_active Ceased
- 2008-09-24 MX MX2010003109A patent/MX2010003109A/es not_active Application Discontinuation
- 2008-09-24 JP JP2010525273A patent/JP5798320B2/ja not_active Expired - Fee Related
- 2008-09-24 EP EP08834443A patent/EP2205734A2/en not_active Withdrawn
- 2008-09-24 AU AU2008303775A patent/AU2008303775A1/en not_active Abandoned
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2564855C2 (ru) * | 2011-04-26 | 2015-10-10 | ОБЩЕСТВО С ОГРАНИЧЕННОЙ ОТВЕТСТВЕННОСТЬЮ "НоваМедика" | Способ получения пэгилированных олигонуклеотидов |
| RU2736499C1 (ru) * | 2017-02-23 | 2020-11-17 | Гуанчжоу Селлпротек Фармасьютикал Ко., Лтд | Специфические ингибиторы гексокиназы-2 для применения при остром повреждении центральной нервной системы |
Also Published As
| Publication number | Publication date |
|---|---|
| KR20100072185A (ko) | 2010-06-30 |
| CN101809154A (zh) | 2010-08-18 |
| WO2009040113A2 (en) | 2009-04-02 |
| BRPI0817260A2 (pt) | 2014-10-14 |
| MX2010003109A (es) | 2010-04-01 |
| EP2205734A2 (en) | 2010-07-14 |
| AU2008303775A1 (en) | 2009-04-02 |
| JP2010539893A (ja) | 2010-12-24 |
| JP5798320B2 (ja) | 2015-10-21 |
| EP2562256A3 (en) | 2013-06-19 |
| US20110046207A1 (en) | 2011-02-24 |
| EP2562256A2 (en) | 2013-02-27 |
| US8507456B2 (en) | 2013-08-13 |
| CA2700441A1 (en) | 2009-04-02 |
| WO2009040113A3 (en) | 2009-06-11 |
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