BRPI0817260A2 - Ácidos nucleicos de ligação a c5a - Google Patents

Ácidos nucleicos de ligação a c5a

Info

Publication number
BRPI0817260A2
BRPI0817260A2 BRPI0817260-9A2A BRPI0817260A BRPI0817260A2 BR PI0817260 A2 BRPI0817260 A2 BR PI0817260A2 BR PI0817260 A BRPI0817260 A BR PI0817260A BR PI0817260 A2 BRPI0817260 A2 BR PI0817260A2
Authority
BR
Brazil
Prior art keywords
nucleating
acids
nucleating acids
Prior art date
Application number
BRPI0817260-9A2A
Other languages
English (en)
Portuguese (pt)
Inventor
Werner Purschke
Florian Jarosch
Dirk Eulberg
Sven Klussmann
Klaus Buchner
Christian Maasch
Original Assignee
Noxxon Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Noxxon Pharma Ag filed Critical Noxxon Pharma Ag
Publication of BRPI0817260A2 publication Critical patent/BRPI0817260A2/pt

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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/713—Double-stranded nucleic acids or oligonucleotides
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    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/16—Aptamers
    • C—CHEMISTRY; METALLURGY
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    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/30—Chemical structure
    • C12N2310/31—Chemical structure of the backbone
    • C12N2310/318—Chemical structure of the backbone where the PO2 is completely replaced, e.g. MMI or formacetal
    • C12N2310/3183—Diol linkers, e.g. glycols or propanediols
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    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/30—Chemical structure
    • C12N2310/32—Chemical structure of the sugar
    • C12N2310/323—Chemical structure of the sugar modified ring structure
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]

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  • Health & Medical Sciences (AREA)
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  • Engineering & Computer Science (AREA)
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  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Diabetes (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Pulmonology (AREA)
  • Neurology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biochemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Neurosurgery (AREA)
  • Biophysics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Endocrinology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
BRPI0817260-9A2A 2007-09-24 2008-09-24 Ácidos nucleicos de ligação a c5a BRPI0817260A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07018750 2007-09-24
PCT/EP2008/008097 WO2009040113A2 (en) 2007-09-24 2008-09-24 C5a BINDING NUCLEIC ACIDS

Publications (1)

Publication Number Publication Date
BRPI0817260A2 true BRPI0817260A2 (pt) 2014-10-14

Family

ID=40174751

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0817260-9A2A BRPI0817260A2 (pt) 2007-09-24 2008-09-24 Ácidos nucleicos de ligação a c5a

Country Status (11)

Country Link
US (1) US8507456B2 (enExample)
EP (2) EP2562256A3 (enExample)
JP (1) JP5798320B2 (enExample)
KR (1) KR20100072185A (enExample)
CN (1) CN101809154A (enExample)
AU (1) AU2008303775A1 (enExample)
BR (1) BRPI0817260A2 (enExample)
CA (1) CA2700441A1 (enExample)
MX (1) MX2010003109A (enExample)
RU (1) RU2010116245A (enExample)
WO (1) WO2009040113A2 (enExample)

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WO2012168803A2 (en) 2011-06-07 2012-12-13 Koninklijke Philips Electronics N.V. Providing nucleotide sequence data
US10531655B2 (en) 2011-12-02 2020-01-14 The Regents Of The University Of California Reperfusion protection solution and uses thereof
BR112014016877B1 (pt) * 2012-01-10 2022-03-15 Aptarion Biotech Ag Molécula de l-ácido nucleico capaz de se ligar a c5a humana, seus usos, bem como composição farmacêutica, complexo, método para a seleção de um antagonista de uma atividade mediada por c5a e kit para a detecção de c5a
CN105849323A (zh) 2013-10-28 2016-08-10 多茨设备公司 过敏原检测
US10238700B2 (en) 2014-01-02 2019-03-26 Genelux Corporation Oncolytic virus adjunct therapy with agents that increase virus infectivity
CN106860867A (zh) * 2017-02-23 2017-06-20 中山大学 己糖激酶2特异性抑制剂在急性中枢神经系统损伤疾病中的应用
EP3553521A1 (en) * 2018-04-12 2019-10-16 Koninklijke Philips N.V. Gingivitis diagnostic methods, uses and kits
WO2025196240A1 (en) 2024-03-20 2025-09-25 Aptarion Biotech Ag Method of treating a disorder with a c5a inhibitor
EP4620474A1 (en) 2024-03-20 2025-09-24 APTARION biotech AG Method of treating a disorder with a c5a inhibitor

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CN101809154A (zh) 2010-08-18
WO2009040113A2 (en) 2009-04-02
MX2010003109A (es) 2010-04-01
EP2205734A2 (en) 2010-07-14
AU2008303775A1 (en) 2009-04-02
JP2010539893A (ja) 2010-12-24
RU2010116245A (ru) 2011-11-10
JP5798320B2 (ja) 2015-10-21
EP2562256A3 (en) 2013-06-19
US20110046207A1 (en) 2011-02-24
EP2562256A2 (en) 2013-02-27
US8507456B2 (en) 2013-08-13
CA2700441A1 (en) 2009-04-02
WO2009040113A3 (en) 2009-06-11

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