CA2700441A1 - C5a binding nucleic acids - Google Patents
C5a binding nucleic acids Download PDFInfo
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- CA2700441A1 CA2700441A1 CA2700441A CA2700441A CA2700441A1 CA 2700441 A1 CA2700441 A1 CA 2700441A1 CA 2700441 A CA2700441 A CA 2700441A CA 2700441 A CA2700441 A CA 2700441A CA 2700441 A1 CA2700441 A1 CA 2700441A1
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| EP07018750 | 2007-09-24 | ||
| EP07018750.5 | 2007-09-24 | ||
| PCT/EP2008/008097 WO2009040113A2 (en) | 2007-09-24 | 2008-09-24 | C5a BINDING NUCLEIC ACIDS |
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| CA2700441A1 true CA2700441A1 (en) | 2009-04-02 |
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| US20120065254A1 (en) * | 2009-03-23 | 2012-03-15 | Noxxon Pharma Ag | C5A binding nucleic acids and the use thereof |
| EP3187877A1 (en) * | 2009-09-25 | 2017-07-05 | XOMA Technology Ltd. | Screening methods |
| CN103608042A (zh) * | 2011-04-26 | 2014-02-26 | 雷加多生物科学公司 | 生产peg化的寡核苷酸的方法 |
| WO2012168803A2 (en) | 2011-06-07 | 2012-12-13 | Koninklijke Philips Electronics N.V. | Providing nucleotide sequence data |
| US10531655B2 (en) | 2011-12-02 | 2020-01-14 | The Regents Of The University Of California | Reperfusion protection solution and uses thereof |
| BR112014016877B1 (pt) * | 2012-01-10 | 2022-03-15 | Aptarion Biotech Ag | Molécula de l-ácido nucleico capaz de se ligar a c5a humana, seus usos, bem como composição farmacêutica, complexo, método para a seleção de um antagonista de uma atividade mediada por c5a e kit para a detecção de c5a |
| CN105849323A (zh) | 2013-10-28 | 2016-08-10 | 多茨设备公司 | 过敏原检测 |
| US10238700B2 (en) | 2014-01-02 | 2019-03-26 | Genelux Corporation | Oncolytic virus adjunct therapy with agents that increase virus infectivity |
| CN106860867A (zh) * | 2017-02-23 | 2017-06-20 | 中山大学 | 己糖激酶2特异性抑制剂在急性中枢神经系统损伤疾病中的应用 |
| EP3553521A1 (en) * | 2018-04-12 | 2019-10-16 | Koninklijke Philips N.V. | Gingivitis diagnostic methods, uses and kits |
| WO2025196240A1 (en) | 2024-03-20 | 2025-09-25 | Aptarion Biotech Ag | Method of treating a disorder with a c5a inhibitor |
| EP4620474A1 (en) | 2024-03-20 | 2025-09-24 | APTARION biotech AG | Method of treating a disorder with a c5a inhibitor |
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| US6395888B1 (en) * | 1996-02-01 | 2002-05-28 | Gilead Sciences, Inc. | High affinity nucleic acid ligands of complement system proteins |
| US6011020A (en) | 1990-06-11 | 2000-01-04 | Nexstar Pharmaceuticals, Inc. | Nucleic acid ligand complexes |
| US6395029B1 (en) | 1999-01-19 | 2002-05-28 | The Children's Hospital Of Philadelphia | Sustained delivery of polyionic bioactive agents |
| US6652886B2 (en) | 2001-02-16 | 2003-11-25 | Expression Genetics | Biodegradable cationic copolymers of poly (alkylenimine) and poly (ethylene glycol) for the delivery of bioactive agents |
| EP1306382A1 (de) | 2001-10-26 | 2003-05-02 | Noxxon Pharma AG | Modifizierte L-Nukleinsäure |
| EP2138575B8 (en) | 2002-02-20 | 2013-07-24 | Mersana Therapeutics, Inc. | Conjugates comprising a biodegradable polymer and uses therefor |
| KR20060015505A (ko) | 2003-04-13 | 2006-02-17 | 엔존 파마슈티컬즈, 인코포레이티드 | 올리고뉴클레오타이드 전구약물 |
| GB0314472D0 (en) | 2003-06-20 | 2003-07-23 | Warwick Effect Polymers Ltd | Polymer |
| US20070116710A1 (en) * | 2004-02-03 | 2007-05-24 | Leonard Bell | Methods of treating hemolytic anemia |
| US20090281296A1 (en) | 2004-02-09 | 2009-11-12 | Supramol Parenteral Colloid Gmbh | Process for the production of conjugates from polysaccharides and polynucelotides |
| US7803931B2 (en) | 2004-02-12 | 2010-09-28 | Archemix Corp. | Aptamer therapeutics useful in the treatment of complement-related disorders |
| PL3385384T3 (pl) * | 2004-02-12 | 2021-03-08 | Archemix Llc | Aptamerowe środki terapeutyczne użyteczne w leczeniu zaburzeń powiązanych z dopełniaczem |
| ES2741524T3 (es) | 2004-03-23 | 2020-02-11 | Ascendis Pharma Gmbh | Profármaco polimérico con un enlazador autoinmolador |
| WO2006052790A2 (en) | 2004-11-05 | 2006-05-18 | The Children's Hospital Of Philadelphia | Biodegradable linkers for molecular therapies |
| HUE026496T2 (en) * | 2006-03-08 | 2016-06-28 | Archemix Llc | Complement-binding aptamers and anti-C5 agents for treating eye diseases |
| CN101534643A (zh) | 2006-09-15 | 2009-09-16 | 安佐制药股份有限公司 | 用于递送寡核苷酸的基于位阻酯的生物可降解连接体 |
| EP2407558A1 (en) | 2006-10-31 | 2012-01-18 | Noxxon Pharma AG | Methods for the detection of a single- or double-stranded nucleic acid molecule |
| US20120065254A1 (en) * | 2009-03-23 | 2012-03-15 | Noxxon Pharma Ag | C5A binding nucleic acids and the use thereof |
-
2008
- 2008-09-24 RU RU2010116245/10A patent/RU2010116245A/ru not_active Application Discontinuation
- 2008-09-24 US US12/679,307 patent/US8507456B2/en not_active Expired - Fee Related
- 2008-09-24 EP EP12006735.0A patent/EP2562256A3/en not_active Withdrawn
- 2008-09-24 BR BRPI0817260-9A2A patent/BRPI0817260A2/pt not_active IP Right Cessation
- 2008-09-24 KR KR1020107005454A patent/KR20100072185A/ko not_active Withdrawn
- 2008-09-24 CN CN200880108439A patent/CN101809154A/zh active Pending
- 2008-09-24 CA CA2700441A patent/CA2700441A1/en not_active Abandoned
- 2008-09-24 WO PCT/EP2008/008097 patent/WO2009040113A2/en not_active Ceased
- 2008-09-24 MX MX2010003109A patent/MX2010003109A/es not_active Application Discontinuation
- 2008-09-24 JP JP2010525273A patent/JP5798320B2/ja not_active Expired - Fee Related
- 2008-09-24 EP EP08834443A patent/EP2205734A2/en not_active Withdrawn
- 2008-09-24 AU AU2008303775A patent/AU2008303775A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| KR20100072185A (ko) | 2010-06-30 |
| CN101809154A (zh) | 2010-08-18 |
| WO2009040113A2 (en) | 2009-04-02 |
| BRPI0817260A2 (pt) | 2014-10-14 |
| MX2010003109A (es) | 2010-04-01 |
| EP2205734A2 (en) | 2010-07-14 |
| AU2008303775A1 (en) | 2009-04-02 |
| JP2010539893A (ja) | 2010-12-24 |
| RU2010116245A (ru) | 2011-11-10 |
| JP5798320B2 (ja) | 2015-10-21 |
| EP2562256A3 (en) | 2013-06-19 |
| US20110046207A1 (en) | 2011-02-24 |
| EP2562256A2 (en) | 2013-02-27 |
| US8507456B2 (en) | 2013-08-13 |
| WO2009040113A3 (en) | 2009-06-11 |
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