RU2009127496A - Шипучие препараты флорфеникола для добавления в системы питьевой воды - Google Patents
Шипучие препараты флорфеникола для добавления в системы питьевой воды Download PDFInfo
- Publication number
- RU2009127496A RU2009127496A RU2009127496/15A RU2009127496A RU2009127496A RU 2009127496 A RU2009127496 A RU 2009127496A RU 2009127496/15 A RU2009127496/15 A RU 2009127496/15A RU 2009127496 A RU2009127496 A RU 2009127496A RU 2009127496 A RU2009127496 A RU 2009127496A
- Authority
- RU
- Russia
- Prior art keywords
- effervescent
- preparation
- effervescent preparation
- acid
- component
- Prior art date
Links
- AYIRNRDRBQJXIF-NXEZZACHSA-N (-)-Florfenicol Chemical compound CS(=O)(=O)C1=CC=C([C@@H](O)[C@@H](CF)NC(=O)C(Cl)Cl)C=C1 AYIRNRDRBQJXIF-NXEZZACHSA-N 0.000 title claims abstract 9
- 239000003651 drinking water Substances 0.000 title claims 2
- 235000020188 drinking water Nutrition 0.000 title claims 2
- 229940079593 drug Drugs 0.000 title abstract 3
- 239000003814 drug Substances 0.000 title abstract 3
- 239000002253 acid Substances 0.000 claims abstract 14
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims abstract 9
- 239000000203 mixture Substances 0.000 claims abstract 9
- 229960003760 florfenicol Drugs 0.000 claims abstract 8
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 claims abstract 4
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical group [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 claims abstract 4
- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 claims abstract 3
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 claims abstract 3
- 235000015165 citric acid Nutrition 0.000 claims abstract 3
- 238000005187 foaming Methods 0.000 claims abstract 3
- 239000011975 tartaric acid Substances 0.000 claims abstract 3
- 235000002906 tartaric acid Nutrition 0.000 claims abstract 3
- BJEPYKJPYRNKOW-REOHCLBHSA-N (S)-malic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O BJEPYKJPYRNKOW-REOHCLBHSA-N 0.000 claims abstract 2
- UIIMBOGNXHQVGW-DEQYMQKBSA-M Sodium bicarbonate-14C Chemical compound [Na+].O[14C]([O-])=O UIIMBOGNXHQVGW-DEQYMQKBSA-M 0.000 claims abstract 2
- BJEPYKJPYRNKOW-UHFFFAOYSA-N alpha-hydroxysuccinic acid Natural products OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 claims abstract 2
- 229910000019 calcium carbonate Inorganic materials 0.000 claims abstract 2
- 235000010216 calcium carbonate Nutrition 0.000 claims abstract 2
- 125000005587 carbonate group Chemical group 0.000 claims abstract 2
- BVKZGUZCCUSVTD-UHFFFAOYSA-N carbonic acid Chemical class OC(O)=O BVKZGUZCCUSVTD-UHFFFAOYSA-N 0.000 claims abstract 2
- 239000001630 malic acid Substances 0.000 claims abstract 2
- 235000011090 malic acid Nutrition 0.000 claims abstract 2
- 229910000028 potassium bicarbonate Inorganic materials 0.000 claims abstract 2
- 235000015497 potassium bicarbonate Nutrition 0.000 claims abstract 2
- 239000011736 potassium bicarbonate Substances 0.000 claims abstract 2
- TYJJADVDDVDEDZ-UHFFFAOYSA-M potassium hydrogencarbonate Chemical compound [K+].OC([O-])=O TYJJADVDDVDEDZ-UHFFFAOYSA-M 0.000 claims abstract 2
- 229910000030 sodium bicarbonate Inorganic materials 0.000 claims abstract 2
- 235000017557 sodium bicarbonate Nutrition 0.000 claims abstract 2
- 241001465754 Metazoa Species 0.000 claims 4
- MUBZPKHOEPUJKR-UHFFFAOYSA-N Oxalic acid Chemical compound OC(=O)C(O)=O MUBZPKHOEPUJKR-UHFFFAOYSA-N 0.000 claims 3
- 239000011230 binding agent Substances 0.000 claims 3
- 208000035143 Bacterial infection Diseases 0.000 claims 2
- VZCYOOQTPOCHFL-OWOJBTEDSA-N Fumaric acid Chemical compound OC(=O)\C=C\C(O)=O VZCYOOQTPOCHFL-OWOJBTEDSA-N 0.000 claims 2
- WNLRTRBMVRJNCN-UHFFFAOYSA-N adipic acid Chemical compound OC(=O)CCCCC(O)=O WNLRTRBMVRJNCN-UHFFFAOYSA-N 0.000 claims 2
- 208000022362 bacterial infectious disease Diseases 0.000 claims 2
- -1 flavorings Substances 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 2
- 239000005660 Abamectin Substances 0.000 claims 1
- 239000001361 adipic acid Substances 0.000 claims 1
- 235000011037 adipic acid Nutrition 0.000 claims 1
- 239000003963 antioxidant agent Substances 0.000 claims 1
- RRZXIRBKKLTSOM-XPNPUAGNSA-N avermectin B1a Chemical compound C1=C[C@H](C)[C@@H]([C@@H](C)CC)O[C@]11O[C@H](C\C=C(C)\[C@@H](O[C@@H]2O[C@@H](C)[C@H](O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](OC)C3)[C@@H](OC)C2)[C@@H](C)\C=C\C=C/2[C@]3([C@H](C(=O)O4)C=C(C)[C@@H](O)[C@H]3OC\2)O)C[C@H]4C1 RRZXIRBKKLTSOM-XPNPUAGNSA-N 0.000 claims 1
- 239000003086 colorant Substances 0.000 claims 1
- 229940111134 coxibs Drugs 0.000 claims 1
- 239000003255 cyclooxygenase 2 inhibitor Substances 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 239000000945 filler Substances 0.000 claims 1
- NOOCSNJCXJYGPE-UHFFFAOYSA-N flunixin Chemical compound C1=CC=C(C(F)(F)F)C(C)=C1NC1=NC=CC=C1C(O)=O NOOCSNJCXJYGPE-UHFFFAOYSA-N 0.000 claims 1
- 229960000588 flunixin Drugs 0.000 claims 1
- 235000003599 food sweetener Nutrition 0.000 claims 1
- 239000001530 fumaric acid Substances 0.000 claims 1
- 235000011087 fumaric acid Nutrition 0.000 claims 1
- LNOPIUAQISRISI-UHFFFAOYSA-N n'-hydroxy-2-propan-2-ylsulfonylethanimidamide Chemical compound CC(C)S(=O)(=O)CC(N)=NO LNOPIUAQISRISI-UHFFFAOYSA-N 0.000 claims 1
- 235000006408 oxalic acid Nutrition 0.000 claims 1
- 239000003755 preservative agent Substances 0.000 claims 1
- 239000002904 solvent Substances 0.000 claims 1
- 239000003381 stabilizer Substances 0.000 claims 1
- 239000004094 surface-active agent Substances 0.000 claims 1
- 239000003765 sweetening agent Substances 0.000 claims 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0007—Effervescent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87070506P | 2006-12-19 | 2006-12-19 | |
| US60/870,705 | 2006-12-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2009127496A true RU2009127496A (ru) | 2011-01-27 |
Family
ID=39496160
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2009127496/15A RU2009127496A (ru) | 2006-12-19 | 2007-12-17 | Шипучие препараты флорфеникола для добавления в системы питьевой воды |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20080145317A1 (enExample) |
| EP (1) | EP2120858A2 (enExample) |
| JP (1) | JP2010513487A (enExample) |
| KR (1) | KR20090090387A (enExample) |
| CN (1) | CN101600418A (enExample) |
| BR (1) | BRPI0720492A2 (enExample) |
| CA (1) | CA2672863A1 (enExample) |
| MX (1) | MX2009006714A (enExample) |
| RU (1) | RU2009127496A (enExample) |
| WO (1) | WO2008085310A2 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2744987C2 (ru) * | 2014-09-09 | 2021-03-17 | Сева Сантэ Анималь | Парентеральные композиции и их применение |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CL2004001293A1 (es) | 2003-05-29 | 2005-05-06 | Schering Plough Ltd | Composicion farmaceutica que comprende compuestos antibacterianos como florfenicol, tiamfenicol, cloramfenicol en combinacion con al menos un portador seleccionado de triacetina, dimetilacetamida o una mezcla de ellas; y su uso en el tratamiento de u |
| EP2102154A1 (en) * | 2006-12-13 | 2009-09-23 | Schering-Plough Ltd. | Water-soluble prodrugs of chloramphenicol, thiamphenicol, and analogs thereof |
| RU2010123282A (ru) * | 2007-11-09 | 2011-12-20 | Интэрвэт Интэрнэшнл Б.Ф. (NL) | Твердая лекарственная форма с быстрым высвобождением активного вещества, ее получение и применение |
| FR2925335B1 (fr) * | 2007-12-21 | 2010-03-19 | Ceva Sante Animale | Compositions orales liquides de florfenicol diluables dans l'eau de boisson |
| JP2011529895A (ja) * | 2008-07-30 | 2011-12-15 | インターベツト・インターナシヨナル・ベー・ベー | フロルフェニコール中間体として有用なオキサゾリン保護アミノジオール化合物を調製する方法 |
| BRPI1002023A2 (pt) * | 2010-03-01 | 2011-10-25 | Nanocore Biotecnologia S A | forma farmacêutica sólida de dissolução rápida para tratamento de infecções bacterianas |
| CN101966200A (zh) * | 2010-07-26 | 2011-02-09 | 天津生机集团股份有限公司 | 用于治疗禽消化道细菌感染的组合物及其制备方法 |
| CN101972237A (zh) * | 2010-08-14 | 2011-02-16 | 格特生物制药（天津）有限公司 | 一种畜禽用泡腾片的制备方法 |
| EP2491920A1 (en) * | 2011-02-25 | 2012-08-29 | Deva Holding Anonim Sirketi | Effervescent tablet, sachet and dry syrup of gemifloxacin |
| WO2014174405A1 (en) * | 2013-04-22 | 2014-10-30 | Webb Johannes Arnoldus Vosloo | Pharmaceutical preparation |
| CN103550755B (zh) * | 2013-11-04 | 2015-05-20 | 河南牧翔动物药业有限公司 | 一种氟苯尼考硫酸粘菌素可溶性粉及其制备方法 |
| CN105640889A (zh) * | 2014-11-11 | 2016-06-08 | 天津嘉创生物科技有限公司 | 氟苯尼考可溶性粉及其制备方法 |
| CN114917193B (zh) * | 2022-05-07 | 2023-05-30 | 广东温氏大华农生物科技有限公司 | 一种适应复杂水质的盐酸金霉素可溶性粉及其制备方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1276839A (en) * | 1968-08-02 | 1972-06-07 | Sandoz Products Ltd | Antibiotic compositions |
| US4655782A (en) * | 1985-12-06 | 1987-04-07 | Lever Brothers Company | Bleach composition of detergent base powder and agglomerated manganese-alluminosilicate catalyst having phosphate salt distributed therebetween |
| DE69102900T3 (de) * | 1990-02-14 | 1998-04-09 | Otsuka Pharma Co Ltd | Brausemischung, deren Herstellung sowie Verwendung. |
| GB9009473D0 (en) * | 1990-04-27 | 1990-06-20 | Beecham Group Plc | Pharmaceutical formulation |
| US6121215A (en) * | 1999-08-27 | 2000-09-19 | Phyzz, Inc. | Foaming effervescent bath product |
| US6503927B1 (en) * | 1999-10-28 | 2003-01-07 | Pentech Pharmaceuticals, Inc. | Amorphous paroxetine composition |
| GB0205253D0 (en) * | 2002-03-06 | 2002-04-17 | Univ Gent | Immediate release pharmaceutical granule compositions and a continuous process for making them |
| US6790867B2 (en) * | 2002-05-20 | 2004-09-14 | Schering-Plough Animal Health Corporation | Compositions and method for treating infection in cattle and swine |
| CL2004001293A1 (es) * | 2003-05-29 | 2005-05-06 | Schering Plough Ltd | Composicion farmaceutica que comprende compuestos antibacterianos como florfenicol, tiamfenicol, cloramfenicol en combinacion con al menos un portador seleccionado de triacetina, dimetilacetamida o una mezcla de ellas; y su uso en el tratamiento de u |
-
2007
- 2007-12-17 US US11/957,668 patent/US20080145317A1/en not_active Abandoned
- 2007-12-17 WO PCT/US2007/025669 patent/WO2008085310A2/en not_active Ceased
- 2007-12-17 EP EP07862951A patent/EP2120858A2/en not_active Withdrawn
- 2007-12-17 BR BRPI0720492-2A patent/BRPI0720492A2/pt not_active IP Right Cessation
- 2007-12-17 CA CA002672863A patent/CA2672863A1/en not_active Abandoned
- 2007-12-17 CN CNA2007800470236A patent/CN101600418A/zh active Pending
- 2007-12-17 JP JP2009542824A patent/JP2010513487A/ja not_active Withdrawn
- 2007-12-17 RU RU2009127496/15A patent/RU2009127496A/ru not_active Application Discontinuation
- 2007-12-17 MX MX2009006714A patent/MX2009006714A/es unknown
- 2007-12-17 KR KR1020097014679A patent/KR20090090387A/ko not_active Withdrawn
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2744987C2 (ru) * | 2014-09-09 | 2021-03-17 | Сева Сантэ Анималь | Парентеральные композиции и их применение |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2010513487A (ja) | 2010-04-30 |
| KR20090090387A (ko) | 2009-08-25 |
| MX2009006714A (es) | 2009-08-31 |
| US20080145317A1 (en) | 2008-06-19 |
| CN101600418A (zh) | 2009-12-09 |
| WO2008085310A3 (en) | 2008-08-21 |
| EP2120858A2 (en) | 2009-11-25 |
| BRPI0720492A2 (pt) | 2014-02-04 |
| WO2008085310A2 (en) | 2008-07-17 |
| CA2672863A1 (en) | 2008-07-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA92 | Acknowledgement of application withdrawn (lack of supplementary materials submitted) |
Effective date: 20120222 |