RU2007110174A - Детское питание, стимулирующее иммунитет - Google Patents
Детское питание, стимулирующее иммунитет Download PDFInfo
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- RU2007110174A RU2007110174A RU2007110174/13A RU2007110174A RU2007110174A RU 2007110174 A RU2007110174 A RU 2007110174A RU 2007110174/13 A RU2007110174/13 A RU 2007110174/13A RU 2007110174 A RU2007110174 A RU 2007110174A RU 2007110174 A RU2007110174 A RU 2007110174A
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- 235000008452 baby food Nutrition 0.000 title claims 3
- 230000036039 immunity Effects 0.000 title 1
- 230000004936 stimulating effect Effects 0.000 title 1
- 239000000203 mixture Substances 0.000 claims abstract 17
- MBMBGCFOFBJSGT-KUBAVDMBSA-N all-cis-docosa-4,7,10,13,16,19-hexaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCC(O)=O MBMBGCFOFBJSGT-KUBAVDMBSA-N 0.000 claims abstract 10
- YZXBAPSDXZZRGB-DOFZRALJSA-N arachidonic acid Chemical compound CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O YZXBAPSDXZZRGB-DOFZRALJSA-N 0.000 claims abstract 10
- 235000014113 dietary fatty acids Nutrition 0.000 claims abstract 10
- 229930195729 fatty acid Natural products 0.000 claims abstract 10
- 239000000194 fatty acid Substances 0.000 claims abstract 10
- 150000004665 fatty acids Chemical class 0.000 claims abstract 10
- 239000005862 Whey Substances 0.000 claims abstract 5
- 102000007544 Whey Proteins Human genes 0.000 claims abstract 5
- 108010046377 Whey Proteins Proteins 0.000 claims abstract 5
- 235000021342 arachidonic acid Nutrition 0.000 claims abstract 5
- 229940114079 arachidonic acid Drugs 0.000 claims abstract 5
- 235000020669 docosahexaenoic acid Nutrition 0.000 claims abstract 5
- 229940090949 docosahexaenoic acid Drugs 0.000 claims abstract 5
- 239000005018 casein Substances 0.000 claims abstract 4
- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 claims abstract 4
- 235000021240 caseins Nutrition 0.000 claims abstract 4
- 235000020978 long-chain polyunsaturated fatty acids Nutrition 0.000 claims abstract 4
- 235000004252 protein component Nutrition 0.000 claims abstract 4
- OYHQOLUKZRVURQ-HZJYTTRNSA-N Linoleic acid Chemical compound CCCCC\C=C/C\C=C/CCCCCCCC(O)=O OYHQOLUKZRVURQ-HZJYTTRNSA-N 0.000 claims abstract 3
- JAZBEHYOTPTENJ-JLNKQSITSA-N all-cis-5,8,11,14,17-icosapentaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O JAZBEHYOTPTENJ-JLNKQSITSA-N 0.000 claims abstract 3
- 150000001720 carbohydrates Chemical class 0.000 claims abstract 3
- 235000020673 eicosapentaenoic acid Nutrition 0.000 claims abstract 3
- 229960005135 eicosapentaenoic acid Drugs 0.000 claims abstract 3
- JAZBEHYOTPTENJ-UHFFFAOYSA-N eicosapentaenoic acid Natural products CCC=CCC=CCC=CCC=CCC=CCCCC(O)=O JAZBEHYOTPTENJ-UHFFFAOYSA-N 0.000 claims abstract 3
- 229920001542 oligosaccharide Polymers 0.000 claims abstract 3
- 150000002482 oligosaccharides Chemical class 0.000 claims abstract 3
- 239000004475 Arginine Substances 0.000 claims abstract 2
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 claims abstract 2
- 235000019197 fats Nutrition 0.000 claims abstract 2
- 235000020778 linoleic acid Nutrition 0.000 claims abstract 2
- OYHQOLUKZRVURQ-IXWMQOLASA-N linoleic acid Natural products CCCCC\C=C/C\C=C\CCCCCCCC(O)=O OYHQOLUKZRVURQ-IXWMQOLASA-N 0.000 claims abstract 2
- 235000016709 nutrition Nutrition 0.000 claims abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 claims abstract 2
- 235000020777 polyunsaturated fatty acids Nutrition 0.000 claims abstract 2
- 235000018102 proteins Nutrition 0.000 claims abstract 2
- 102000004169 proteins and genes Human genes 0.000 claims abstract 2
- 108090000623 proteins and genes Proteins 0.000 claims abstract 2
- 208000027866 inflammatory disease Diseases 0.000 claims 2
- 229960004232 linoleic acid Drugs 0.000 claims 2
- 238000006116 polymerization reaction Methods 0.000 claims 2
- 201000004624 Dermatitis Diseases 0.000 claims 1
- 206010012438 Dermatitis atopic Diseases 0.000 claims 1
- 206010012735 Diarrhoea Diseases 0.000 claims 1
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical class OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 claims 1
- 206010020751 Hypersensitivity Diseases 0.000 claims 1
- 229920001202 Inulin Polymers 0.000 claims 1
- AYFVYJQAPQTCCC-UHFFFAOYSA-N Threonine Natural products CC(O)C(N)C(O)=O AYFVYJQAPQTCCC-UHFFFAOYSA-N 0.000 claims 1
- 239000004473 Threonine Substances 0.000 claims 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 claims 1
- 239000002253 acid Substances 0.000 claims 1
- 208000030961 allergic reaction Diseases 0.000 claims 1
- 201000008937 atopic dermatitis Diseases 0.000 claims 1
- 208000010668 atopic eczema Diseases 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 238000009776 industrial production Methods 0.000 claims 1
- JYJIGFIDKWBXDU-MNNPPOADSA-N inulin Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)OC[C@]1(OC[C@]2(OC[C@]3(OC[C@]4(OC[C@]5(OC[C@]6(OC[C@]7(OC[C@]8(OC[C@]9(OC[C@]%10(OC[C@]%11(OC[C@]%12(OC[C@]%13(OC[C@]%14(OC[C@]%15(OC[C@]%16(OC[C@]%17(OC[C@]%18(OC[C@]%19(OC[C@]%20(OC[C@]%21(OC[C@]%22(OC[C@]%23(OC[C@]%24(OC[C@]%25(OC[C@]%26(OC[C@]%27(OC[C@]%28(OC[C@]%29(OC[C@]%30(OC[C@]%31(OC[C@]%32(OC[C@]%33(OC[C@]%34(OC[C@]%35(OC[C@]%36(O[C@@H]%37[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O%37)O)[C@H]([C@H](O)[C@@H](CO)O%36)O)[C@H]([C@H](O)[C@@H](CO)O%35)O)[C@H]([C@H](O)[C@@H](CO)O%34)O)[C@H]([C@H](O)[C@@H](CO)O%33)O)[C@H]([C@H](O)[C@@H](CO)O%32)O)[C@H]([C@H](O)[C@@H](CO)O%31)O)[C@H]([C@H](O)[C@@H](CO)O%30)O)[C@H]([C@H](O)[C@@H](CO)O%29)O)[C@H]([C@H](O)[C@@H](CO)O%28)O)[C@H]([C@H](O)[C@@H](CO)O%27)O)[C@H]([C@H](O)[C@@H](CO)O%26)O)[C@H]([C@H](O)[C@@H](CO)O%25)O)[C@H]([C@H](O)[C@@H](CO)O%24)O)[C@H]([C@H](O)[C@@H](CO)O%23)O)[C@H]([C@H](O)[C@@H](CO)O%22)O)[C@H]([C@H](O)[C@@H](CO)O%21)O)[C@H]([C@H](O)[C@@H](CO)O%20)O)[C@H]([C@H](O)[C@@H](CO)O%19)O)[C@H]([C@H](O)[C@@H](CO)O%18)O)[C@H]([C@H](O)[C@@H](CO)O%17)O)[C@H]([C@H](O)[C@@H](CO)O%16)O)[C@H]([C@H](O)[C@@H](CO)O%15)O)[C@H]([C@H](O)[C@@H](CO)O%14)O)[C@H]([C@H](O)[C@@H](CO)O%13)O)[C@H]([C@H](O)[C@@H](CO)O%12)O)[C@H]([C@H](O)[C@@H](CO)O%11)O)[C@H]([C@H](O)[C@@H](CO)O%10)O)[C@H]([C@H](O)[C@@H](CO)O9)O)[C@H]([C@H](O)[C@@H](CO)O8)O)[C@H]([C@H](O)[C@@H](CO)O7)O)[C@H]([C@H](O)[C@@H](CO)O6)O)[C@H]([C@H](O)[C@@H](CO)O5)O)[C@H]([C@H](O)[C@@H](CO)O4)O)[C@H]([C@H](O)[C@@H](CO)O3)O)[C@H]([C@H](O)[C@@H](CO)O2)O)[C@@H](O)[C@H](O)[C@@H](CO)O1 JYJIGFIDKWBXDU-MNNPPOADSA-N 0.000 claims 1
- 229940029339 inulin Drugs 0.000 claims 1
- 239000002777 nucleoside Substances 0.000 claims 1
- 125000003835 nucleoside group Chemical group 0.000 claims 1
- 239000002773 nucleotide Substances 0.000 claims 1
- 125000003729 nucleotide group Chemical group 0.000 claims 1
- 229920001277 pectin Polymers 0.000 claims 1
- 239000001814 pectin Substances 0.000 claims 1
- 235000010987 pectin Nutrition 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 239000011701 zinc Substances 0.000 claims 1
- 229910052725 zinc Inorganic materials 0.000 claims 1
- DTOSIQBPPRVQHS-PDBXOOCHSA-N alpha-linolenic acid Chemical compound CC\C=C/C\C=C/C\C=C/CCCCCCCC(O)=O DTOSIQBPPRVQHS-PDBXOOCHSA-N 0.000 abstract 2
- 235000020661 alpha-linolenic acid Nutrition 0.000 abstract 1
- 235000013350 formula milk Nutrition 0.000 abstract 1
- 229960004488 linolenic acid Drugs 0.000 abstract 1
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- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/201—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having one or two double bonds, e.g. oleic, linoleic acids
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- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
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Claims (11)
1. Питательная или фармацевтическая композиция в виде детского питания, содержащая жировой компонент, белковый компонент и углеводный компонент и включающая молочную сыворотку и казеин, отличающаяся тем, что весовое соотношение казеина к молочной сыворотке составляет от 1:1 до 1:2,4, при этом композиция содержит
a) по меньшей мере 3 г аргинина на 100 г белка;
b) по меньшей мере 10 вес.% линолевой кислоты от общего содержания жирных кислот;
с) по меньшей мере 1 вес.% альфа-линолевой кислоты от общего содержания жирных кислот;
d) по меньшей мере одну длинноцепочечную полиненасыщенную жирную кислоту в количестве, превышающем 0,1 вес.%, от общего содержания жирных кислот, причем указанная длинноцепочечная полиненасыщенная жирная кислота выбрана из группы, состоящей из докозагексаеновой кислоты, арахидоновой кислоты и эйкозапентаеновой кислоты;
e) 5-25 вес.% по меньшей мере одной полиненасыщенной жирной кислоты от общего содержания жирных кислот;
f) 2-12 г неусвояемых олигосахаридов, имеющих степень полимеризации от 2 до 100 на 100 г сухого веса данной композиции и
g) кислые олигосахариды со степенью полимеризации от 2 до 100.
2. Композиция по п.1, отличающаяся тем, что содержит трансгалактоолигосахариды, пектиновый гидролизат и по меньшей мере один компонент, выбранный из группы, состоящей из фруктоолигосахариды и инулина.
3. Композиция по п.1, отличающаяся тем, что содержит докозагексаеновую кислоту, арахидоновую кислоту и эйкозапентаеновую кислоту.
4. Композиция по любому из пп.1-3, отличающаяся тем, что содержит 2-100 мг цинка на 100 г сухого веса данной композиции.
5. Композиция по любому из пп.1-3, отличающаяся тем, что белковый компонент составляет 5-15 эн.%, жировой компонент составляет 30-60 эн.%, а углеводный компонент составляет 25-75 эн.%.
6. Композиция по любому из пп.1-3, отличающаяся тем, что она дополнительно содержит между 5 и 100 мг нуклеотидов и/или между 5 и 100 мг нуклеозидов на 100 г сухого веса данной композиции.
7. Композиция по любому из пп.1-3, отличающаяся тем, что содержит 2-6 г треонина на 100 г белкового компонента.
8. Композиция по любому из пп.1-3, отличающаяся тем, что содержит докозагексаеновую кислоту в количестве, превышающем 0,1 вес.% от общего содержания жирных кислот, и арахидоновую кислоту в количестве, превышающем 0,1 вес.% от общего содержания жирных кислот, и тем, что весовое соотношение арахидоновая кислота/докозагексаеновая кислота составляет от 0,25 до 25.
9. Применение композиции по любому из пп.1-8 при промышленном производстве детского питания или лекарственного средства, применяемого для младенца при лечении и/или профилактике воспалительного заболевания, диареи, экземы и/или атопического дерматита.
10. Применение по п.9, в котором воспалительное заболевание представляет собой аллергическую реакцию.
11. Применение по п.9 или 10, в котором данная композиция вводится в организм энтерально или перорально.
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| EP04019856A EP1634599A1 (en) | 2004-08-20 | 2004-08-20 | Iimmune stimulatory infant nutrition |
| EP04019856.6 | 2004-08-20 |
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| RU2007110173/15A RU2404785C2 (ru) | 2004-08-20 | 2005-08-22 | Детское питание |
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| EP (3) | EP1634599A1 (ru) |
| JP (2) | JP4965444B2 (ru) |
| CN (3) | CN101766228B (ru) |
| AT (1) | ATE427112T1 (ru) |
| AU (2) | AU2005274266B2 (ru) |
| BR (2) | BRPI0514526A (ru) |
| CA (2) | CA2576042C (ru) |
| DE (1) | DE602005013679D1 (ru) |
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| RU (2) | RU2426549C2 (ru) |
| UA (1) | UA88918C2 (ru) |
| WO (2) | WO2006018314A2 (ru) |
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| US10435427B2 (en) | 2013-10-04 | 2019-10-08 | Jennewein Biotechnologie Gmbh | Process for purification of neutral human milk oligosaccharide using simulated moving bed chromatography |
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2004
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- 2005-08-19 PL PL05777309T patent/PL1781307T3/pl unknown
- 2005-08-19 EP EP05777309A patent/EP1781307B1/en not_active Revoked
- 2005-08-19 UA UAA200702905A patent/UA88918C2/ru unknown
- 2005-08-19 RU RU2007110174/10A patent/RU2426549C2/ru not_active IP Right Cessation
- 2005-08-19 AT AT05777309T patent/ATE427112T1/de not_active IP Right Cessation
- 2005-08-19 JP JP2007526399A patent/JP4965444B2/ja active Active
- 2005-08-19 US US11/660,594 patent/US8114441B2/en not_active Expired - Fee Related
- 2005-08-19 DE DE602005013679T patent/DE602005013679D1/de active Active
- 2005-08-19 BR BRPI0514526-0A patent/BRPI0514526A/pt not_active Application Discontinuation
- 2005-08-19 CN CNA2005800281714A patent/CN101048167A/zh active Pending
- 2005-08-19 NZ NZ553248A patent/NZ553248A/en not_active IP Right Cessation
- 2005-08-19 CA CA2576042A patent/CA2576042C/en not_active Expired - Fee Related
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- 2005-08-22 WO PCT/NL2005/000609 patent/WO2006019300A2/en active Application Filing
- 2005-08-22 CA CA002577698A patent/CA2577698A1/en not_active Abandoned
- 2005-08-22 EP EP05775170A patent/EP1781306A2/en not_active Withdrawn
- 2005-08-22 AU AU2005273099A patent/AU2005273099B2/en not_active Ceased
- 2005-08-22 NZ NZ553299A patent/NZ553299A/en not_active Application Discontinuation
- 2005-08-22 BR BRPI0514498-1A patent/BRPI0514498A/pt not_active IP Right Cessation
- 2005-08-22 US US11/573,939 patent/US20080125346A1/en not_active Abandoned
- 2005-08-22 CN CNA2005800351685A patent/CN101039686A/zh active Pending
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10435427B2 (en) | 2013-10-04 | 2019-10-08 | Jennewein Biotechnologie Gmbh | Process for purification of neutral human milk oligosaccharide using simulated moving bed chromatography |
| US11168105B2 (en) | 2013-10-04 | 2021-11-09 | Jennewein Biotechnologie Gmbh | Process for purification of neutral human milk oligosaccharide using simulated moving bed chromatography |
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