RU2005108667A - Производные n-биарилметиламиноциклоалканкарбоксамида - Google Patents
Производные n-биарилметиламиноциклоалканкарбоксамида Download PDFInfo
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- RU2005108667A RU2005108667A RU2005108667/04A RU2005108667A RU2005108667A RU 2005108667 A RU2005108667 A RU 2005108667A RU 2005108667/04 A RU2005108667/04 A RU 2005108667/04A RU 2005108667 A RU2005108667 A RU 2005108667A RU 2005108667 A RU2005108667 A RU 2005108667A
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- optionally substituted
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- YXFVVABEGXRONW-UHFFFAOYSA-N Cc1ccccc1 Chemical compound Cc1ccccc1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 description 1
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- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US40674202P | 2002-08-29 | 2002-08-29 | |
| US60/406,742 | 2002-08-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2005108667A true RU2005108667A (ru) | 2005-08-27 |
Family
ID=31978351
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2005108667/04A RU2005108667A (ru) | 2002-08-29 | 2003-08-25 | Производные n-биарилметиламиноциклоалканкарбоксамида |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US7163951B2 (enExample) |
| EP (1) | EP1545538A2 (enExample) |
| JP (1) | JP2005537323A (enExample) |
| KR (1) | KR20050033660A (enExample) |
| CN (1) | CN1678320A (enExample) |
| AU (1) | AU2003265674B2 (enExample) |
| BR (1) | BR0313239A (enExample) |
| CA (1) | CA2495914A1 (enExample) |
| IL (1) | IL166426A0 (enExample) |
| MX (1) | MXPA05002245A (enExample) |
| NO (1) | NO20051539L (enExample) |
| PL (1) | PL374529A1 (enExample) |
| RU (1) | RU2005108667A (enExample) |
| WO (1) | WO2004019868A2 (enExample) |
| ZA (1) | ZA200500471B (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2866988C2 (ru) * | 2022-01-14 | 2026-07-27 | Ухань Хьюманвелл Инновейтив Драг Рисерч Энд Девелопмент Сентер Лимитед Компани | Диарильное соединение в качестве ингибитора для двух мишеней тубулина/src, соединение b, способ получения диарильного соединения, фармацевтическая композиция, применение диарильного соединения и способ ингибирования киназы src |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7332499B2 (en) * | 2003-08-07 | 2008-02-19 | Merck & Co., Inc. | Sulfonyl substituted n-(biarylmethyl) aminocyclopropanecarboxamides |
| CN1976915A (zh) | 2004-02-11 | 2007-06-06 | 史密丝克莱恩比彻姆公司 | Hiv整合酶抑制剂 |
| CA2557858A1 (en) * | 2004-03-02 | 2005-09-15 | Merck & Co., Inc. | Amino cyclopropane carboxamide derivatives as bradykinin antagonists |
| US7429604B2 (en) | 2004-06-15 | 2008-09-30 | Bristol Myers Squibb Company | Six-membered heterocycles useful as serine protease inhibitors |
| US20060217362A1 (en) * | 2004-12-29 | 2006-09-28 | Tung Jay S | Novel compounds useful for bradykinin B1 receptor antagonism |
| AU2006255642A1 (en) * | 2005-06-03 | 2006-12-14 | Merck Sharp & Dohme Corp. | 1-Hydroxycycloalkanecarboxamide derivatives as bradykinin antagonists |
| AU2006325746A1 (en) * | 2005-12-14 | 2007-06-21 | Bristol-Myers Squibb Company | Six-membered heterocycles useful as serine protease inhibitors |
| CL2008002545A1 (es) | 2007-08-29 | 2009-10-23 | Boehringer Ingelheim Int | Compuestos derivados de fenoxi-bencil-carbamoilo; composicion farmaceutica; procedimiento para preparar la composicion farmaceutica; y su uso en el tratamiento del dolor. |
| CA2722704A1 (en) * | 2008-04-28 | 2009-11-05 | Zalicus Pharmaceuticals Ltd. | Cyclylamine derivatives as calcium channel blockers |
| TW201024279A (en) * | 2008-09-18 | 2010-07-01 | Jerini Ag | Use of B1 receptor antagonists |
| WO2010097373A1 (de) * | 2009-02-26 | 2010-09-02 | Boehringer Ingelheim International Gmbh | Verbindungen als bradykinin b1 antagonisten |
| PT2401256E (pt) * | 2009-02-26 | 2013-05-13 | Boehringer Ingelheim Int | Compostos como antagonistas da bradicinina b1 |
| BRPI1012581A2 (pt) * | 2009-06-02 | 2016-03-29 | Boehringer Ingelheim Int | derivados de amidas de ácido 6, 7-di-hidro-5h-imidazol[1,2-a]imidazol-3-carboxílico |
| KR101628132B1 (ko) * | 2010-01-25 | 2016-06-08 | 주식회사 바이오씨에스 | 신규한 바이아릴아미드 유도체 및 이를 유효성분으로 함유하는 조성물 |
| MA34008B1 (fr) | 2010-02-23 | 2013-02-01 | Boehringer Ingelheim Int | Composes en tant qu'antagonistes de la bradykinine b1 |
| US8937073B2 (en) * | 2010-08-20 | 2015-01-20 | Boehringer Ingelheim International Gmbh | Disubstituted tetrahydrofuranyl compounds and their use as B1-receptor antagonists |
| HUP1000598A2 (en) * | 2010-11-05 | 2012-09-28 | Richter Gedeon Nyrt | Indole derivatives |
| US8912221B2 (en) * | 2010-12-27 | 2014-12-16 | Hoffmann-La Roche Inc. | Biaryl amide derivatives |
| US8592426B2 (en) * | 2011-01-24 | 2013-11-26 | Hoffmann—La Roche Inc. | Aryl-benzocycloalkyl amide derivatives |
| NO2686520T3 (enExample) * | 2011-06-06 | 2018-03-17 | ||
| HUE066123T2 (hu) | 2013-06-13 | 2024-07-28 | Akebia Therapeutics Inc | Készítmények és módszerek anémia kezelésére |
| CA2974691A1 (en) | 2015-01-23 | 2016-07-28 | Akebia Therapeutics, Inc. | Solid forms of 2-(5-(3-fluorophenyl)-3-hydroxypicolinamido)acetic acid, compositions, and uses thereof |
| NZ735973A (en) | 2015-04-01 | 2023-06-30 | Akebia Therapeutics Inc | Compositions and methods for treating anemia |
| US11713298B2 (en) | 2018-05-09 | 2023-08-01 | Akebia Therapeutics, Inc. | Process for preparing 2-[[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino]acetic acid |
| US12612367B2 (en) | 2019-12-10 | 2026-04-28 | Akebia Therapeutics, Inc. | Method for producing nitrogen-containing heteroarylcarboxamide acetic acid derivative |
| WO2021216530A1 (en) | 2020-04-20 | 2021-10-28 | Akebia Therapeutics, Inc. | Treatment of viral infections, of organ injury, and of related conditions using a hif prolyl hydroxylase inhibitor or a hif-alpha stabilizer |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5023265A (en) * | 1990-06-01 | 1991-06-11 | Schering Corporation | Substituted 1-H-pyrrolopyridine-3-carboxamides |
| IL99372A0 (en) | 1990-09-10 | 1992-08-18 | Ciba Geigy Ag | Azacyclic compounds |
| TWI259079B (en) | 2002-02-08 | 2006-08-01 | Merck & Co Inc | N-biphenyl(substituted methyl)aminocycloalkanecarboxamide derivatives |
| DE60303441T2 (de) | 2002-02-08 | 2006-09-21 | Merck & Co., Inc. | N-biphenylmethylaminocycloalkancarboxamid-derivative |
-
2003
- 2003-08-25 IL IL16642603A patent/IL166426A0/xx unknown
- 2003-08-25 US US10/523,911 patent/US7163951B2/en not_active Expired - Fee Related
- 2003-08-25 KR KR1020057003550A patent/KR20050033660A/ko not_active Withdrawn
- 2003-08-25 WO PCT/US2003/026628 patent/WO2004019868A2/en not_active Ceased
- 2003-08-25 PL PL03374529A patent/PL374529A1/xx not_active Application Discontinuation
- 2003-08-25 MX MXPA05002245A patent/MXPA05002245A/es not_active Application Discontinuation
- 2003-08-25 BR BR0313239-0A patent/BR0313239A/pt not_active Application Discontinuation
- 2003-08-25 RU RU2005108667/04A patent/RU2005108667A/ru not_active Application Discontinuation
- 2003-08-25 JP JP2004532994A patent/JP2005537323A/ja active Pending
- 2003-08-25 AU AU2003265674A patent/AU2003265674B2/en not_active Ceased
- 2003-08-25 EP EP03791763A patent/EP1545538A2/en not_active Withdrawn
- 2003-08-25 CN CNA03820293XA patent/CN1678320A/zh active Pending
- 2003-08-25 CA CA002495914A patent/CA2495914A1/en not_active Abandoned
-
2005
- 2005-01-18 ZA ZA2005/00471A patent/ZA200500471B/en unknown
- 2005-03-23 NO NO20051539A patent/NO20051539L/no unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2866988C2 (ru) * | 2022-01-14 | 2026-07-27 | Ухань Хьюманвелл Инновейтив Драг Рисерч Энд Девелопмент Сентер Лимитед Компани | Диарильное соединение в качестве ингибитора для двух мишеней тубулина/src, соединение b, способ получения диарильного соединения, фармацевтическая композиция, применение диарильного соединения и способ ингибирования киназы src |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2495914A1 (en) | 2004-03-11 |
| WO2004019868A2 (en) | 2004-03-11 |
| WO2004019868A3 (en) | 2004-04-29 |
| MXPA05002245A (es) | 2005-06-08 |
| IL166426A0 (en) | 2006-01-15 |
| NO20051539L (no) | 2005-05-25 |
| ZA200500471B (en) | 2006-07-26 |
| US7163951B2 (en) | 2007-01-16 |
| KR20050033660A (ko) | 2005-04-12 |
| AU2003265674A1 (en) | 2004-03-19 |
| US20050288305A1 (en) | 2005-12-29 |
| EP1545538A2 (en) | 2005-06-29 |
| AU2003265674B2 (en) | 2008-12-11 |
| JP2005537323A (ja) | 2005-12-08 |
| CN1678320A (zh) | 2005-10-05 |
| BR0313239A (pt) | 2005-06-14 |
| PL374529A1 (en) | 2005-10-31 |
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| FA92 | Acknowledgement of application withdrawn (lack of supplementary materials submitted) |
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