RU2003126447A - Вакцины на основе субъединиц с супермотивами а2 - Google Patents
Вакцины на основе субъединиц с супермотивами а2 Download PDFInfo
- Publication number
- RU2003126447A RU2003126447A RU2003126447/15A RU2003126447A RU2003126447A RU 2003126447 A RU2003126447 A RU 2003126447A RU 2003126447/15 A RU2003126447/15 A RU 2003126447/15A RU 2003126447 A RU2003126447 A RU 2003126447A RU 2003126447 A RU2003126447 A RU 2003126447A
- Authority
- RU
- Russia
- Prior art keywords
- epitope
- subsequence
- indicated
- hla
- peptide
- Prior art date
Links
- 229960005486 vaccine Drugs 0.000 title 1
- 238000000034 method Methods 0.000 claims 29
- 150000001413 amino acids Chemical class 0.000 claims 25
- 108090000765 processed proteins & peptides Proteins 0.000 claims 21
- 239000000427 antigen Substances 0.000 claims 13
- 108091007433 antigens Proteins 0.000 claims 13
- 102000036639 antigens Human genes 0.000 claims 13
- 102000025850 HLA-A2 Antigen Human genes 0.000 claims 12
- 108010074032 HLA-A2 Antigen Proteins 0.000 claims 12
- 239000012634 fragment Substances 0.000 claims 11
- 108700028369 Alleles Proteins 0.000 claims 4
- 125000003275 alpha amino acid group Chemical group 0.000 claims 4
- 125000000539 amino acid group Chemical group 0.000 claims 4
- 230000028993 immune response Effects 0.000 claims 4
- 230000001939 inductive effect Effects 0.000 claims 4
- 210000001151 cytotoxic T lymphocyte Anatomy 0.000 claims 2
- 230000005867 T cell response Effects 0.000 claims 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6806—Determination of free amino acids
- G01N33/6812—Assays for specific amino acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Pathology (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Biophysics (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26496901P | 2001-01-29 | 2001-01-29 | |
| US60/264,969 | 2001-01-29 | ||
| US09/935,476 US20040096445A1 (en) | 1999-06-30 | 2001-08-22 | Subunit vaccines with A2 supermotifs |
| US09/935,476 | 2001-08-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2003126447A true RU2003126447A (ru) | 2005-02-27 |
Family
ID=26950859
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2003126447/15A RU2003126447A (ru) | 2001-01-29 | 2002-01-29 | Вакцины на основе субъединиц с супермотивами а2 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20040096445A1 (enExample) |
| EP (1) | EP1368659A2 (enExample) |
| JP (1) | JP2005512016A (enExample) |
| KR (1) | KR20040052475A (enExample) |
| CN (1) | CN1653337A (enExample) |
| AU (1) | AU2002243730B2 (enExample) |
| CA (1) | CA2432995C (enExample) |
| CZ (1) | CZ20032054A3 (enExample) |
| IL (1) | IL156660A0 (enExample) |
| MX (1) | MXPA03006581A (enExample) |
| NZ (1) | NZ526860A (enExample) |
| RU (1) | RU2003126447A (enExample) |
| SK (1) | SK9512003A3 (enExample) |
| WO (1) | WO2002061435A2 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7611713B2 (en) * | 1993-03-05 | 2009-11-03 | Pharmexa Inc. | Inducing cellular immune responses to hepatitis B virus using peptide compositions |
| US20110097352A9 (en) * | 1992-01-29 | 2011-04-28 | Pharmexa Inc. | Inducing cellular immune responses to hepatitis B virus using peptide and nucleic acid compositions |
| US9340577B2 (en) | 1992-08-07 | 2016-05-17 | Epimmune Inc. | HLA binding motifs and peptides and their uses |
| EP1078092B1 (en) * | 1998-05-13 | 2011-08-03 | Epimmune Inc. | Expression vectors for stimulating an immune response and methods of using the same |
| JP2003509465A (ja) * | 1999-07-19 | 2003-03-11 | エピミューン， インコーポレイテッド | ペプチドおよび核酸組成物を使用する、ｃ型肝炎ウイルスに対する細胞性免疫応答の誘導 |
| US7026443B1 (en) * | 1999-12-10 | 2006-04-11 | Epimmune Inc. | Inducing cellular immune responses to human Papillomavirus using peptide and nucleic acid compositions |
| US7462354B2 (en) * | 1999-12-28 | 2008-12-09 | Pharmexa Inc. | Method and system for optimizing minigenes and peptides encoded thereby |
| US20040248113A1 (en) * | 1999-12-28 | 2004-12-09 | Alessandro Sette | Method and system for optimizing multi-epitope nucleic acid constructs and peptides encoded thereby |
| WO2005012502A2 (en) * | 2003-03-28 | 2005-02-10 | Idm Pharma, Inc. | Methods of identifying optimal variants of peptide epitopes |
| EP2391635B1 (en) | 2009-01-28 | 2017-04-26 | Epimmune Inc. | Pan-dr binding polypeptides and uses thereof |
| CN110214275B (zh) * | 2016-12-01 | 2022-12-06 | 南托米克斯有限责任公司 | 肿瘤抗原性加工和呈递 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2370413A1 (en) * | 1999-06-29 | 2001-01-04 | Epimmune Inc. | Hla binding peptides and their uses |
| AU2605501A (en) * | 1999-12-21 | 2001-07-03 | Epimmune, Inc. | Inducing cellular immune responses to prostate cancer antigens using peptide andnucleic acid compositions |
-
2001
- 2001-08-22 US US09/935,476 patent/US20040096445A1/en not_active Abandoned
-
2002
- 2002-01-29 IL IL15666002A patent/IL156660A0/xx unknown
- 2002-01-29 SK SK951-2003A patent/SK9512003A3/sk not_active Application Discontinuation
- 2002-01-29 AU AU2002243730A patent/AU2002243730B2/en not_active Ceased
- 2002-01-29 CN CNA028042484A patent/CN1653337A/zh active Pending
- 2002-01-29 MX MXPA03006581A patent/MXPA03006581A/es not_active Application Discontinuation
- 2002-01-29 NZ NZ526860A patent/NZ526860A/en unknown
- 2002-01-29 CA CA2432995A patent/CA2432995C/en not_active Expired - Fee Related
- 2002-01-29 JP JP2002561950A patent/JP2005512016A/ja active Pending
- 2002-01-29 WO PCT/US2002/002708 patent/WO2002061435A2/en not_active Ceased
- 2002-01-29 EP EP02709233A patent/EP1368659A2/en not_active Withdrawn
- 2002-01-29 KR KR10-2003-7010024A patent/KR20040052475A/ko not_active Ceased
- 2002-01-29 CZ CZ20032054A patent/CZ20032054A3/cs unknown
- 2002-01-29 RU RU2003126447/15A patent/RU2003126447A/ru not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1368659A2 (en) | 2003-12-10 |
| CA2432995A1 (en) | 2002-08-08 |
| NZ526860A (en) | 2007-03-30 |
| KR20040052475A (ko) | 2004-06-23 |
| SK9512003A3 (en) | 2003-12-02 |
| IL156660A0 (en) | 2004-01-04 |
| AU2002243730B2 (en) | 2007-07-12 |
| JP2005512016A (ja) | 2005-04-28 |
| WO2002061435A3 (en) | 2003-07-10 |
| WO2002061435A2 (en) | 2002-08-08 |
| US20040096445A1 (en) | 2004-05-20 |
| CA2432995C (en) | 2011-07-26 |
| CN1653337A (zh) | 2005-08-10 |
| CZ20032054A3 (cs) | 2003-12-17 |
| MXPA03006581A (es) | 2004-06-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA92 | Acknowledgement of application withdrawn (lack of supplementary materials submitted) |
Effective date: 20060818 |