CA2432995C - Immunogenic hla-a2 supermotif-restricted peptides - Google Patents

Immunogenic hla-a2 supermotif-restricted peptides Download PDF

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Publication number
CA2432995C
CA2432995C CA2432995A CA2432995A CA2432995C CA 2432995 C CA2432995 C CA 2432995C CA 2432995 A CA2432995 A CA 2432995A CA 2432995 A CA2432995 A CA 2432995A CA 2432995 C CA2432995 C CA 2432995C
Authority
CA
Canada
Prior art keywords
peptide
antigen
amino acids
xaa
peptides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2432995A
Other languages
English (en)
French (fr)
Other versions
CA2432995A1 (en
Inventor
John Sidney
Alessandro Sette
Howard M. Grey
Scott Southwood
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmexa Inc
Original Assignee
Pharmexa Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmexa Inc filed Critical Pharmexa Inc
Publication of CA2432995A1 publication Critical patent/CA2432995A1/en
Application granted granted Critical
Publication of CA2432995C publication Critical patent/CA2432995C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6806Determination of free amino acids
    • G01N33/6812Assays for specific amino acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • G01N2500/04Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biophysics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CA2432995A 2001-01-29 2002-01-29 Immunogenic hla-a2 supermotif-restricted peptides Expired - Fee Related CA2432995C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US26496901P 2001-01-29 2001-01-29
US60/264,969 2001-01-29
US09/935,476 US20040096445A1 (en) 1999-06-30 2001-08-22 Subunit vaccines with A2 supermotifs
US09/935,476 2001-08-22
PCT/US2002/002708 WO2002061435A2 (en) 2001-01-29 2002-01-29 Subunit vaccines with a2 supermotifs

Publications (2)

Publication Number Publication Date
CA2432995A1 CA2432995A1 (en) 2002-08-08
CA2432995C true CA2432995C (en) 2011-07-26

Family

ID=26950859

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2432995A Expired - Fee Related CA2432995C (en) 2001-01-29 2002-01-29 Immunogenic hla-a2 supermotif-restricted peptides

Country Status (14)

Country Link
US (1) US20040096445A1 (enExample)
EP (1) EP1368659A2 (enExample)
JP (1) JP2005512016A (enExample)
KR (1) KR20040052475A (enExample)
CN (1) CN1653337A (enExample)
AU (1) AU2002243730B2 (enExample)
CA (1) CA2432995C (enExample)
CZ (1) CZ20032054A3 (enExample)
IL (1) IL156660A0 (enExample)
MX (1) MXPA03006581A (enExample)
NZ (1) NZ526860A (enExample)
RU (1) RU2003126447A (enExample)
SK (1) SK9512003A3 (enExample)
WO (1) WO2002061435A2 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7611713B2 (en) * 1993-03-05 2009-11-03 Pharmexa Inc. Inducing cellular immune responses to hepatitis B virus using peptide compositions
US20110097352A9 (en) * 1992-01-29 2011-04-28 Pharmexa Inc. Inducing cellular immune responses to hepatitis B virus using peptide and nucleic acid compositions
US9340577B2 (en) 1992-08-07 2016-05-17 Epimmune Inc. HLA binding motifs and peptides and their uses
EP1078092B1 (en) * 1998-05-13 2011-08-03 Epimmune Inc. Expression vectors for stimulating an immune response and methods of using the same
JP2003509465A (ja) * 1999-07-19 2003-03-11 エピミューン, インコーポレイテッド ペプチドおよび核酸組成物を使用する、c型肝炎ウイルスに対する細胞性免疫応答の誘導
US7026443B1 (en) * 1999-12-10 2006-04-11 Epimmune Inc. Inducing cellular immune responses to human Papillomavirus using peptide and nucleic acid compositions
US7462354B2 (en) * 1999-12-28 2008-12-09 Pharmexa Inc. Method and system for optimizing minigenes and peptides encoded thereby
US20040248113A1 (en) * 1999-12-28 2004-12-09 Alessandro Sette Method and system for optimizing multi-epitope nucleic acid constructs and peptides encoded thereby
WO2005012502A2 (en) * 2003-03-28 2005-02-10 Idm Pharma, Inc. Methods of identifying optimal variants of peptide epitopes
EP2391635B1 (en) 2009-01-28 2017-04-26 Epimmune Inc. Pan-dr binding polypeptides and uses thereof
CN110214275B (zh) * 2016-12-01 2022-12-06 南托米克斯有限责任公司 肿瘤抗原性加工和呈递

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2370413A1 (en) * 1999-06-29 2001-01-04 Epimmune Inc. Hla binding peptides and their uses
AU2605501A (en) * 1999-12-21 2001-07-03 Epimmune, Inc. Inducing cellular immune responses to prostate cancer antigens using peptide andnucleic acid compositions

Also Published As

Publication number Publication date
EP1368659A2 (en) 2003-12-10
CA2432995A1 (en) 2002-08-08
NZ526860A (en) 2007-03-30
KR20040052475A (ko) 2004-06-23
SK9512003A3 (en) 2003-12-02
IL156660A0 (en) 2004-01-04
AU2002243730B2 (en) 2007-07-12
JP2005512016A (ja) 2005-04-28
WO2002061435A3 (en) 2003-07-10
WO2002061435A2 (en) 2002-08-08
US20040096445A1 (en) 2004-05-20
RU2003126447A (ru) 2005-02-27
CN1653337A (zh) 2005-08-10
CZ20032054A3 (cs) 2003-12-17
MXPA03006581A (es) 2004-06-25

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Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed

Effective date: 20130129