RS57523B1 - Pirazolski derivati kao modulatori kalcijumskih kanala aktiviranih oslobađanjem kalcijuma - Google Patents

Pirazolski derivati kao modulatori kalcijumskih kanala aktiviranih oslobađanjem kalcijuma

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Publication number
RS57523B1
RS57523B1 RS20180824A RSP20180824A RS57523B1 RS 57523 B1 RS57523 B1 RS 57523B1 RS 20180824 A RS20180824 A RS 20180824A RS P20180824 A RSP20180824 A RS P20180824A RS 57523 B1 RS57523 B1 RS 57523B1
Authority
RS
Serbia
Prior art keywords
pyrazol
cyclopropyl
substituted
trifluoromethyl
unsubstituted
Prior art date
Application number
RS20180824A
Other languages
English (en)
Serbian (sr)
Inventor
Peyyappan Muthuppalaniappan
Srikant Viswanadha
Gayatri Swaroop Merikapudi
Swaroop Kumar V S Vakkalanka
Original Assignee
Rhizen Pharmaceuticals S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhizen Pharmaceuticals S A filed Critical Rhizen Pharmaceuticals S A
Publication of RS57523B1 publication Critical patent/RS57523B1/sr

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    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
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    • A61K31/415—1,2-Diazoles
    • A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • A61K31/5375—1,4-Oxazines, e.g. morpholine
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